chr3:14,272,392–14,272,931

chr3 : 14,272,392 – 14,272,931

539 bp 132 TFs 6 linked genes

This 539 bp open chromatin element is linked to 6 target genes and is bound by 132 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LSM3		93.9 kb	Distal	Multiome
XPC		94.1 kb	Distal	Multiome
SLC6A6		129.8 kb	Distal	Multiome
TMEM43		147.7 kb	Distal	Multiome
CHCHD4		147.9 kb	Distal	Multiome
GRIP2		283.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

132 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

ChIP K562 ENCFF817JQF 409 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BACH1 1 dataset

ChIP K562 ENCFF419VIM 408 bp overlap

BCOR 3 datasets

ChIP K562 ENCFF343XWA 52 bp overlap

ChIP K562 ENCFF343XWA 253 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap

CAVIN1 1 dataset

ChIP K562 ENCFF731YBD 129 bp overlap

ChIP K562 ENCFF933NKI 78 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCFF432ZEW 305 bp overlap

CREB3 2 datasets

ChIP K562 ENCFF985QJI 271 bp overlap

ChIP K562 ENCFF985QJI 63 bp overlap

ChIP K562 ENCFF902MYN 341 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 217 bp overlap

DDX20 1 dataset

ChIP K562 ENCFF373BEC 237 bp overlap

DMBX1 2 datasets

ChIP K562 ENCFF972HXB 211 bp overlap

ChIP K562 ENCFF972HXB 73 bp overlap

ChIP K562 ENCFF922ILX 301 bp overlap

ChIP K562 ENCFF688PUB 382 bp overlap

ChIP K562 ENCFF622HMZ 385 bp overlap

ChIP K562 ENCFF235VCG 261 bp overlap

ChIP K562 ENCFF626IQJ 293 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 171 bp overlap

ChIP K562 ENCFF389WTI 123 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 391 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 248 bp overlap

ChIP DE DE-GATA6-2 508 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 441 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 434 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 499 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 462 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 392 bp overlap

GMEB1 1 dataset

ChIP K562 ENCFF679VBB 253 bp overlap

GTF2A2 1 dataset

ChIP K562 ENCFF041WRN 391 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HDAC8 2 datasets

ChIP K562 ENCFF784HCJ 281 bp overlap

ChIP K562 ENCFF784HCJ 78 bp overlap

HIF1A 1 dataset

Motif DE_12h DE_12h-HIF1A_MA1106.2 6 bp overlap

HINFP 1 dataset

ChIP K562 ENCFF361QXJ 269 bp overlap

HIVEP1 1 dataset

ChIP K562 ENCFF983WKN 214 bp overlap

ChIP K562 ENCFF158CQE 209 bp overlap

ChIP K562 ENCFF170RNI 267 bp overlap

ChIP K562 ENCFF055LPP 229 bp overlap

IRF1 3 datasets

ChIP K562 ENCFF277KTJ 336 bp overlap

ChIP K562 ENCFF277KTJ 132 bp overlap

ChIP WTC11 ENCFF506LYD 377 bp overlap

ChIP K562 ENCFF346PQL 86 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 539 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 539 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 539 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 485 bp overlap

KDM1A 3 datasets

ChIP H1 ENCFF696SGD 309 bp overlap

ChIP K562 ENCFF128TYE 120 bp overlap

ChIP K562 ENCFF934ZRG 90 bp overlap

KLF13 1 dataset

ChIP K562 ENCFF738YZC 225 bp overlap

KLF6 2 datasets

ChIP K-562 ENCSR297CGF.KLF6.K-562 185 bp overlap

ChIP K562 ENCFF948QSP 250 bp overlap

ChIP K562 ENCFF982GSZ 357 bp overlap

MECOM 1 dataset

ChIP K562 ENCFF773RGL 232 bp overlap

MEF2D 3 datasets

ChIP K-562 ENCSR647ZXA.MEF2D.K-562 200 bp overlap

ChIP K562 ENCFF392LDT 180 bp overlap

ChIP K562 ENCFF392LDT 64 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

ChIP K562 ENCFF811XMB 291 bp overlap

ChIP K562 ENCFF972ENM 214 bp overlap

ChIP K562 ENCFF295NDX 319 bp overlap

ChIP K562 ENCFF295NDX 111 bp overlap

NANOG 6 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 362 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 332 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 539 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 539 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 380 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFATC4 1 dataset

ChIP WTC11 ENCFF744MZI 271 bp overlap

ChIP K562 ENCFF047YKA 298 bp overlap

NFE2L1 1 dataset

ChIP K562 ENCFF138UHK 228 bp overlap

ChIP K562 ENCFF382SJS 272 bp overlap

NFXL1 1 dataset

ChIP K562 ENCFF898RYR 304 bp overlap

NR2C1 2 datasets

ChIP K-562 ENCSR178DEG.NR2C1.K-562 199 bp overlap

ChIP K562 ENCFF568JLK 193 bp overlap

NR4A1 2 datasets

ChIP K-562 ENCSR130PDE.NR4A1.K-562 190 bp overlap

ChIP K562 ENCFF998LHF 203 bp overlap

NR5A2 1 dataset

ChIP A549 ENCFF834RVE 248 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

ChIP WTC11 ENCFF634NAO 234 bp overlap

POLR2A 2 datasets

ChIP H1 ENCFF566JSR 478 bp overlap

ChIP H1 ENCFF833NJP 359 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 539 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 539 bp overlap

PRRX2 1 dataset

ChIP WTC11 ENCFF107JGJ 233 bp overlap

PTTG1 1 dataset

ChIP K562 ENCFF017KRM 177 bp overlap

ChIP K562 ENCFF176LBI 113 bp overlap

PYGO2 1 dataset

ChIP K562 ENCFF458IIA 191 bp overlap

ChIP K562 ENCFF892SPR 263 bp overlap

ChIP K562 ENCFF685YZN 279 bp overlap

RREB1 1 dataset

ChIP K562 ENCFF796IEO 298 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 396 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 381 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 455 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 539 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 479 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 336 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 445 bp overlap

SMAD3 2 datasets

ChIP K-562 ENCSR376XAV.SMAD3.K-562 169 bp overlap

ChIP K562 ENCFF885DQE 220 bp overlap

SMAD4 1 dataset

ChIP K562 ENCFF628RBP 251 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 295 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 418 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCFF827PZY 214 bp overlap

ChIP K562 ENCFF972RAQ 246 bp overlap

ChIP K562 ENCFF314WLE 233 bp overlap

TBX18 1 dataset

ChIP K562 ENCFF473CJK 305 bp overlap

TCF15 1 dataset

ChIP K562 ENCFF099NVR 244 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF465AQA 234 bp overlap

TEAD2 1 dataset

ChIP K562 ENCFF039ZWC 215 bp overlap

ChIP SUIT-2 GSE115461.TP63.SUIT-2 131 bp overlap

TRERF1 1 dataset

ChIP WTC11 ENCFF113BUM 189 bp overlap

TSHZ1 2 datasets

ChIP K-562 ENCSR958JPH.TSHZ1.K-562 179 bp overlap

ChIP K562 ENCFF289XHG 223 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 116 bp overlap

ZBTB11 2 datasets

ChIP K562 ENCFF215OUF 444 bp overlap

ChIP K562 ENCFF215OUF 107 bp overlap

ZBTB12 1 dataset

ChIP K562 ENCFF933CVM 289 bp overlap

ZBTB17 2 datasets

ChIP K562 ENCFF731UTU 303 bp overlap

ChIP K562 ENCFF731UTU 101 bp overlap

ZBTB26 1 dataset

ChIP K562 ENCFF766TDN 228 bp overlap

ZBTB40 1 dataset

ChIP K562 ENCFF337GJB 339 bp overlap

ZBTB9 1 dataset

ChIP K562 ENCFF233EFX 274 bp overlap

ZKSCAN8 1 dataset

ChIP K562 ENCFF387ETI 409 bp overlap

ZNF121 1 dataset

ChIP K562 ENCFF314GND 133 bp overlap

ZNF134 1 dataset

ChIP K562 ENCFF502NWS 300 bp overlap

ZNF175 2 datasets

ChIP K562 ENCFF497AEJ 370 bp overlap

ChIP K562 ENCFF497AEJ 171 bp overlap

ZNF197 1 dataset

ChIP K562 ENCFF872BAU 356 bp overlap

ZNF212 1 dataset

ChIP K562 ENCFF640NBC 236 bp overlap

ZNF215 1 dataset

ChIP K562 ENCFF317MOH 254 bp overlap

ZNF239 1 dataset

ChIP K562 ENCFF703IKI 261 bp overlap

ZNF24 2 datasets

ChIP K562 ENCFF497GLV 288 bp overlap

ChIP K562 ENCFF497GLV 87 bp overlap

ZNF281 2 datasets

ChIP K562 ENCFF594VNM 223 bp overlap

ChIP K562 ENCFF594VNM 80 bp overlap

ZNF311 3 datasets

ChIP K-562 ENCSR388ZRV.ZNF311.K-562 204 bp overlap

ChIP K562 ENCFF986QSP 144 bp overlap

ChIP K562 ENCFF986QSP 62 bp overlap

ZNF354B 2 datasets

ChIP K562 ENCFF120AXZ 219 bp overlap

ChIP K562 ENCFF955JQT 352 bp overlap

ZNF395 1 dataset

ChIP K562 ENCFF464EIT 427 bp overlap

ZNF396 1 dataset

ChIP WTC11 ENCFF776JWJ 186 bp overlap

ZNF398 1 dataset

ChIP K562 ENCFF664RQO 230 bp overlap

ZNF41 1 dataset

ChIP K562 ENCFF693FMG 216 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 239 bp overlap

ZNF444 1 dataset

ChIP K562 ENCFF329VCH 288 bp overlap

ZNF449 2 datasets

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ChIP K562 ENCFF038VEZ 234 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF507 1 dataset

ChIP K562 ENCFF235JOG 216 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF561 1 dataset

ChIP K562 ENCFF420RQB 234 bp overlap

ZNF57 1 dataset

ChIP K562 ENCFF527CQA 259 bp overlap

ZNF583 2 datasets

ChIP K-562 ENCSR775EQV.ZNF583.K-562 201 bp overlap

ChIP K562 ENCFF879KXH 255 bp overlap

ZNF584 1 dataset

ChIP K562 ENCFF771INO 415 bp overlap

ZNF589 2 datasets

ChIP K562 ENCFF770FHN 449 bp overlap

ChIP K562 ENCFF770FHN 246 bp overlap

ZNF592 3 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 231 bp overlap

ChIP K562 ENCFF547OSS 321 bp overlap

ChIP K562 ENCFF547OSS 321 bp overlap

ZNF639 1 dataset

ChIP K562 ENCFF271FQR 57 bp overlap

ZNF644 1 dataset

ChIP K562 ENCFF290PDB 361 bp overlap

ZNF668 1 dataset

ChIP K562 ENCFF112IUE 228 bp overlap

ZNF671 1 dataset

ChIP WTC11 ENCFF053HBV 265 bp overlap

ZNF695 1 dataset

ChIP K562 ENCFF648DBO 230 bp overlap

ZNF707 1 dataset

ChIP K562 ENCFF243WRW 275 bp overlap

ZNF740 1 dataset

ChIP K562 ENCFF447IXE 376 bp overlap

ZNF76 1 dataset

ChIP K562 ENCFF267KQX 260 bp overlap

ZNF766 2 datasets

ChIP K562 ENCFF348LDO 331 bp overlap

ChIP K562 ENCFF348LDO 121 bp overlap

ZNF83 1 dataset

ChIP K562 ENCFF340RTV 323 bp overlap

ZSCAN18 1 dataset

ChIP WTC11 ENCFF867QWX 187 bp overlap