chr22:39,020,588–39,021,215

chr22 : 39,020,588 – 39,021,215

627 bp 149 TFs 11 linked genes

This 627 bp open chromatin element is linked to 11 target genes and is bound by 149 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
APOBEC3D		at TSS	At TSS	Proximity
ENSG00000284554		6.2 kb	Proximal	Proximity
APOBEC3C		6.3 kb	Proximal	Proximity
APOBEC3F		19.9 kb	Distal	Multiome
APOBEC3G		56.3 kb	Distal	Multiome
CBX7		131.6 kb	Distal	Multiome
CBX6		148.7 kb	Distal	Multiome
PDGFB		222.1 kb	Distal	Multiome
DNAL4		226.8 kb	Distal	Multiome
SUN2		226.8 kb	Distal	Multiome
RPL3		298.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

149 transcription factors

ChIP K562 ENCFF583EEH 224 bp overlap

ChIP K562 ENCFF025NLP 435 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 152 bp overlap

ChIP K562 ENCFF938UXQ 288 bp overlap

ATF1 2 datasets

ChIP K562 ENCFF817JQF 396 bp overlap

ChIP K562 ENCFF817JQF 178 bp overlap

ATF7 3 datasets

ChIP GM12878 ENCFF037PYH 139 bp overlap

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 138 bp overlap

ChIP K562 ENCFF308SKS 377 bp overlap

BCLAF1 1 dataset

ChIP GM12878 ENCFF306JRM 419 bp overlap

ChIP K562 ENCFF343XWA 88 bp overlap

BHLHE22 1 dataset

Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 525 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 160 bp overlap

ChIP K562 ENCFF480JXZ 163 bp overlap

Bach1::Mafk 1 dataset

Motif DE_24h DE_24h-Bach1Mafk_MA0591.2 12 bp overlap

CBFA2T3 2 datasets

ChIP K562 ENCFF673OEZ 172 bp overlap

ChIP K562 ENCFF673OEZ 133 bp overlap

CBFB 2 datasets

ChIP WTC11 ENCFF113HIY 158 bp overlap

ChIP WTC11 ENCFF113HIY 359 bp overlap

CC2D1A 1 dataset

ChIP K562 ENCFF567XUT 134 bp overlap

CTCF 3 datasets

Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap

ChIP chondrocyte ENCFF134ORZ 487 bp overlap

ChIP transverse colon ENCFF749DPF 388 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 367 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 301 bp overlap

ChIP BLaER1 ENCFF093OYK 395 bp overlap

ChIP BLaER1 ENCFF364PUR 329 bp overlap

DPF2 3 datasets

ChIP GM12878 ENCFF681AJV 72 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 61 bp overlap

ChIP K562 ENCFF775HUO 244 bp overlap

ChIP GM12878 ENCFF910KAC 258 bp overlap

E4F1 4 datasets

ChIP GM12878 ENCFF007QKJ 217 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 155 bp overlap

ChIP K562 ENCFF622HMZ 367 bp overlap

ChIP K562 ENCFF622HMZ 161 bp overlap

ChIP K562 ENCFF113OPQ 234 bp overlap

ELF1 2 datasets

ChIP GM12878 ENCFF692SMY 61 bp overlap

ChIP K562 ENCFF457KVR 239 bp overlap

EP400 1 dataset

ChIP K562 ENCFF850OZQ 385 bp overlap

ERF::FIGLA 1 dataset

Motif DE_24h DE_24h-ERFFIGLA_MA1934.2 13 bp overlap

ChIP K562 ENCFF389WTI 220 bp overlap

ETV2::FIGLA 1 dataset

Motif DE_24h DE_24h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_24h DE_24h-ETV5FIGLA_MA1945.2 14 bp overlap

GABPA 1 dataset

ChIP K562 ENCFF139LXS 396 bp overlap

GABPB1 2 datasets

ChIP K-562 ENCSR138YYY.GABPB1.K-562 138 bp overlap

ChIP K562 ENCFF015GDS 322 bp overlap

GATA1 2 datasets

ChIP erythroblast ENCFF867JAR 576 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 291 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 399 bp overlap

ChIP DE DE-GATA4-2 431 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 423 bp overlap

ChIP DE DE-GATA6-2 431 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 568 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 419 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 602 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 551 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 265 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 367 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 234 bp overlap

GLIS2 2 datasets

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 170 bp overlap

ChIP HEK293 ENCFF446EIF 299 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 550 bp overlap

GTF3C2 1 dataset

ChIP T98G GSE120162.GTF3C2.T98G 106 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR711VWL.HDAC1.K-562 145 bp overlap

ChIP K562 ENCFF928TKZ 237 bp overlap

HDAC2 2 datasets

ChIP K562 ENCFF744ALD 283 bp overlap

ChIP K562 ENCFF744ALD 82 bp overlap

IKZF1 5 datasets

ChIP GM12878 ENCFF753XDO 172 bp overlap

ChIP GM12878 ENCFF824TGK 107 bp overlap

ChIP K562 ENCFF348IBL 232 bp overlap

ChIP K562 ENCFF771OHZ 212 bp overlap

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 136 bp overlap

IKZF2 2 datasets

ChIP GM12878 ENCFF918AID 76 bp overlap

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 85 bp overlap

IRF1 2 datasets

ChIP K562 ENCFF277KTJ 391 bp overlap

ChIP K562 ENCFF277KTJ 180 bp overlap

KLF10 1 dataset

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

KLF12 1 dataset

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

KLF14 2 datasets

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

KLF5 3 datasets

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

ChIP GM12878 ENCFF570KBU 178 bp overlap

L3MBTL2 1 dataset

ChIP K562 ENCFF320EQC 157 bp overlap

ChIP K562 ENCFF198WCP 327 bp overlap

Motif DE_24h DE_24h-MAF_MA1520.2 13 bp overlap

Motif DE_24h DE_24h-MAF_MA1520.2 13 bp overlap

MAFA 2 datasets

Motif DE_24h DE_24h-MAFA_MA1521.2 13 bp overlap

Motif DE_24h DE_24h-MAFA_MA1521.2 13 bp overlap

Motif DE_24h DE_24h-MAFK_MA0496.4 10 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

ChIP HEK293 ENCFF994GSG 391 bp overlap

ChIP HEK293 ENCSR290SSQ.MAZ.HEK293 176 bp overlap

ChIP K562 ENCFF731XJJ 68 bp overlap

MLLT1 4 datasets

ChIP GM12878 ENCFF995GXC 256 bp overlap

ChIP GM12878 ENCFF995GXC 256 bp overlap

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 165 bp overlap

ChIP K562 ENCFF074XRJ 163 bp overlap

ChIP K-562 ENCSR390VGH.MNT.K-562 136 bp overlap

ChIP K562 ENCFF450LDL 338 bp overlap

ChIP K562 ENCFF820IGH 343 bp overlap

ChIP GM12878 ENCFF615CWQ 119 bp overlap

Mafg 2 datasets

Motif DE_24h DE_24h-Mafg_MA0659.4 12 bp overlap

Motif DE_24h DE_24h-Mafg_MA0659.4 12 bp overlap

ChIP GM12878 ENCFF213ZNN 228 bp overlap

ChIP GM12878 ENCSR278SQL.NBN.GM12878 149 bp overlap

ChIP K562 ENCFF146YTY 203 bp overlap

NCOA1 1 dataset

ChIP K562 ENCFF962VHQ 277 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF866HRM 311 bp overlap

NELFA 1 dataset

ChIP K-562_HS GSE112379.NELFA.K-562_HS 175 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 160 bp overlap

NFATC3 2 datasets

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 145 bp overlap

ChIP K562 ENCFF078EKB 337 bp overlap

ChIP GM12878 ENCFF392NLB 51 bp overlap

NKX2-2 1 dataset

Motif DE_24h DE_24h-NKX2-2_MA1645.2 8 bp overlap

NR2C2 3 datasets

ChIP K562 ENCFF750AXF 627 bp overlap

ChIP K562 ENCFF750AXF 523 bp overlap

ChIP K562 ENCFF750AXF 267 bp overlap

NR2F1 2 datasets

ChIP GM12878 ENCFF273VKX 132 bp overlap

ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 81 bp overlap

NR2F2 1 dataset

ChIP liver ENCFF565JGD 338 bp overlap

NRF1 2 datasets

ChIP K562 ENCFF689EWI 417 bp overlap

ChIP K562 ENCFF791UHF 397 bp overlap

Neurod2 1 dataset

Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap

PATZ1 1 dataset

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

PBX3 2 datasets

ChIP GM12878 ENCFF285BQQ 217 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 111 bp overlap

PHF21A 1 dataset

ChIP K562 ENCFF088QME 283 bp overlap

ChIP K562 ENCFF217UCA 250 bp overlap

PKNOX1 2 datasets

ChIP GM12878 ENCFF589FCY 303 bp overlap

ChIP K562 ENCFF236IUS 315 bp overlap

POLR2A 21 datasets

ChIP GM15510 ENCFF880HVJ 265 bp overlap

ChIP GM19099 ENCFF726IBN 342 bp overlap

ChIP GM19099 ENCFF726IBN 140 bp overlap

ChIP K562 ENCFF215CWW 287 bp overlap

ChIP K562 ENCFF836GHX 146 bp overlap

ChIP Raji ENCFF613VGX 315 bp overlap

ChIP body of pancreas ENCFF501FEC 348 bp overlap

ChIP body of pancreas ENCFF675RCN 411 bp overlap

ChIP esophagus squamous epithelium ENCFF708IOX 435 bp overlap

ChIP gastroesophageal sphincter ENCFF826EZZ 341 bp overlap

ChIP prostate gland ENCFF881OMH 269 bp overlap

ChIP sigmoid colon ENCFF725QFT 258 bp overlap

ChIP spleen ENCFF044PYR 230 bp overlap

ChIP spleen ENCFF446ZGT 622 bp overlap

ChIP spleen ENCFF706IUS 481 bp overlap

ChIP spleen ENCFF706IUS 151 bp overlap

ChIP spleen ENCFF955VIQ 209 bp overlap

ChIP transverse colon ENCFF193UMS 499 bp overlap

ChIP uterus ENCFF208ADI 409 bp overlap

ChIP uterus ENCFF208ADI 202 bp overlap

ChIP vagina ENCFF384GAB 108 bp overlap

POLR2B 1 dataset

ChIP K562 ENCFF513ENO 103 bp overlap

POLR2G 5 datasets

ChIP K562 ENCFF047BLG 396 bp overlap

ChIP K562 ENCFF047BLG 353 bp overlap

ChIP K562 ENCFF047BLG 154 bp overlap

ChIP K562 ENCFF648YPL 553 bp overlap

ChIP K562 ENCFF648YPL 289 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 627 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 627 bp overlap

RBFOX2 2 datasets

ChIP K562 ENCFF196WTG 201 bp overlap

ChIP K562 ENCFF967GRF 457 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 155 bp overlap

ChIP K562 ENCFF685YZN 97 bp overlap

ChIP K562 ENCFF809XVG 334 bp overlap

ChIP K562 ENCFF998IPA 294 bp overlap

ChIP K562 ENCFF998IPA 92 bp overlap

SKIL 2 datasets

ChIP GM12878 ENCFF171OVM 267 bp overlap

ChIP GM12878 ENCSR212YKD.SKIL.GM12878 86 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 264 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 269 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 450 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 517 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 627 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 614 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 627 bp overlap

SMAD4 1 dataset

ChIP K562 ENCFF628RBP 179 bp overlap

SMAD5 1 dataset

ChIP K562 ENCFF941FJJ 319 bp overlap

SMARCA4 1 dataset

ChIP K562 ENCFF506JCB 388 bp overlap

SMARCA5 3 datasets

ChIP GM12878 ENCFF327LDR 103 bp overlap

ChIP GM12878 ENCSR706YUH.SMARCA5.GM12878 77 bp overlap

ChIP K562 ENCFF936KHY 159 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 559 bp overlap

Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap

ChIP K562 ENCFF088XXV 545 bp overlap

ChIP K562 ENCFF088XXV 326 bp overlap

ChIP K562 ENCFF088XXV 124 bp overlap

ChIP WTC11 ENCFF688PEU 442 bp overlap

ChIP liver ENCFF597LFJ 309 bp overlap

ChIP liver ENCFF769YSM 345 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

ChIP HEK293 ENCFF733RBE 324 bp overlap

ChIP HEK293 ENCFF733RBE 102 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 144 bp overlap

SPDEF 1 dataset

Motif DE_24h DE_24h-SPDEF_MA0686.2 10 bp overlap

STAT1 1 dataset

ChIP GM12878 ENCFF655XMZ 203 bp overlap

SUPT5H 2 datasets

ChIP K562 ENCFF902PAW 178 bp overlap

ChIP K562 ENCFF902PAW 79 bp overlap

ChIP K562 ENCFF314WLE 148 bp overlap

ChIP GM12878 ENCFF571OXR 295 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCFF951HUW 343 bp overlap

TCF12 1 dataset

ChIP K562 ENCFF909RDY 287 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 398 bp overlap

TFAP4 2 datasets

ChIP K562 ENCFF727PXG 497 bp overlap

ChIP K562 ENCFF727PXG 354 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_24h DE_24h-TFAP4ETV1_MA1966.2 13 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_24h DE_24h-TFAP4FLI1_MA1967.2 14 bp overlap

TFDP1 1 dataset

Motif DE_24h DE_24h-TFDP1_MA1122.2 8 bp overlap

ChIP K562 ENCFF620NFN 66 bp overlap

TRIM22 1 dataset

ChIP GM12878 ENCFF313QBQ 113 bp overlap

Tcf12 1 dataset

Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap

VEZF1 2 datasets

ChIP K562 ENCFF053XDV 562 bp overlap

ChIP K562 ENCFF053XDV 436 bp overlap

ChIP GM12878 ENCFF641EEK 134 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 164 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 202 bp overlap

ZBED4 1 dataset

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 238 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 174 bp overlap

ZBTB40 2 datasets

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 158 bp overlap

ChIP K562 ENCFF521DSV 129 bp overlap

ZBTB6 1 dataset

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

ZBTB7C 1 dataset

Motif DE_24h DE_24h-ZBTB7C_MA0695.2 8 bp overlap

ZC3H8 1 dataset

ChIP K562 ENCFF495URH 207 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 146 bp overlap

ZFP91 2 datasets

ChIP HepG2 ENCFF012CME 227 bp overlap

ChIP K562 ENCFF501CDP 229 bp overlap

ChIP K562 ENCFF536AJO 364 bp overlap

ChIP HEK293 ENCFF033NQQ 314 bp overlap

ZMYM3 1 dataset

ChIP HepG2 ENCFF408KTI 239 bp overlap

ZNF148 1 dataset

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF263 1 dataset

ChIP K562 ENCFF640RNA 163 bp overlap

ZNF281 3 datasets

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ChIP K-562 GSE121133.ZNF281.K-562 294 bp overlap

ChIP K562 ENCFF594VNM 254 bp overlap

ZNF282 1 dataset

ChIP K562 ENCFF657WOV 293 bp overlap

ZNF319 1 dataset

ChIP K562 ENCFF561ZSB 198 bp overlap

ZNF331 1 dataset

Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 297 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 146 bp overlap

ZNF362 2 datasets

ChIP HEK293 ENCFF436CGE 166 bp overlap

ChIP HepG2 ENCFF256AZN 172 bp overlap

ZNF384 6 datasets

ChIP GM12878 ENCFF229VSP 259 bp overlap

ChIP HEK293T ENCFF019DZX 239 bp overlap

ChIP HEK293T ENCSR882ICT.ZNF384.HEK293T 221 bp overlap

ChIP HepG2 ENCFF129PLC 249 bp overlap

ChIP K-562 ENCSR000EFP.ZNF384.K-562 111 bp overlap

ChIP K562 ENCFF365NXQ 243 bp overlap

ZNF407 3 datasets

ChIP K562 ENCFF568QZW 209 bp overlap

ChIP K562 ENCFF893ASX 275 bp overlap

ChIP K562 ENCFF893ASX 74 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF682 1 dataset

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

ZNF687 2 datasets

ChIP HepG2 ENCFF653WIX 202 bp overlap

ChIP HepG2 ENCFF653WIX 480 bp overlap

ZNF701 1 dataset

Motif DE_24h DE_24h-ZNF701_MA1987.2 17 bp overlap

ZNF707 1 dataset

Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCFF468FCG 196 bp overlap

ChIP HepG2 ENCFF233UVH 266 bp overlap