chr5:178,994,469–178,995,315

chr5 : 178,994,469 – 178,995,315

846 bp 118 TFs 7 linked genes

This 846 bp open chromatin element is linked to 7 target genes and is bound by 118 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
GRM6		at TSS	At TSS	Proximity
ZNF879		28.9 kb	Distal	Multiome
ZNF354C		65.5 kb	Distal	Multiome
ZFP2		99.0 kb	Distal	Multiome
ZNF354B		134.9 kb	Distal	Multiome
AACSP1		176.4 kb	Distal	Multiome
ZNF354A		264.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

118 transcription factors

ARID1B 1 dataset

ChIP MCF-7_shJUN GSE128445.ARID1B.MCF-7_shJUN 179 bp overlap

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 397 bp overlap

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 341 bp overlap

Motif ES_0h ES_0h-ATF6_MA1466.2 13 bp overlap

Ahr::Arnt 1 dataset

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 648 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 846 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 72 bp overlap

BRD4 9 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 151 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 279 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 273 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 680 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 656 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 504 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 84 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 90 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 360 bp overlap

CBFB 2 datasets

ChIP ME-1 GSE46044.CBFB.ME-1 106 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 274 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.CBX7.HEK293T_PCGF2fl 312 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 238 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 209 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 237 bp overlap

ChIP WTC11 ENCFF209ZUE 383 bp overlap

CTCF 3 datasets

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 320 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 436 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 723 bp overlap

CTCFL 2 datasets

ChIP K-562 GSE70764.CTCFL.K-562 462 bp overlap

ChIP delta-47 GSE70764.CTCFL.delta-47 325 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 207 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 461 bp overlap

ChIP WTC11 ENCFF994SXO 389 bp overlap

ChIP WTC11 ENCFF574OKJ 410 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 247 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 846 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 330 bp overlap

ChIP WTC11 ENCFF789GJO 347 bp overlap

EP300 3 datasets

ChIP neural ENCSR843ZUP.EP300.neural 315 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 255 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 334 bp overlap

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 202 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 767 bp overlap

ChIP K-562 GSE23730.ERG.K-562 98 bp overlap

ChIP K-562 GSE23730.ERG.K-562 223 bp overlap

ESR1 3 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 138 bp overlap

ChIP Ishikawa GSE99905.ESR1.Ishikawa 207 bp overlap

ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 182 bp overlap

ESRRA 1 dataset

ChIP WTC11 ENCFF591YCA 384 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

EZH2 23 datasets

ChIP A-673 ENCSR179SAO.EZH2.A-673 263 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 287 bp overlap

ChIP GM23338 ENCFF613YON 235 bp overlap

ChIP H1 ENCFF232NZA 446 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 225 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 318 bp overlap

ChIP astrocyte ENCFF365JTP 460 bp overlap

ChIP astrocyte ENCFF365JTP 240 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 236 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 206 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 239 bp overlap

ChIP hESC GSE113817.EZH2.hESC 830 bp overlap

ChIP hESC_KO GSE113817.EZH2.hESC_KO 567 bp overlap

ChIP hESC_KO GSE113817.EZH2.hESC_KO 130 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 288 bp overlap

ChIP neural progenitor cell ENCFF018MKA 418 bp overlap

ChIP neural progenitor cell ENCFF472NFV 312 bp overlap

ChIP neural progenitor cell ENCFF472NFV 364 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 342 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 428 bp overlap

ChIP prostate-cancer_HA GSE107780.EZH2.prostate-cancer_HA 413 bp overlap

ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 461 bp overlap

ChIP prostate-cancer_shEZH2 GSE107780.EZH2.prostate-cancer_shEZH2 341 bp overlap

EZH2_phosphoT487 3 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 312 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 299 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 344 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 364 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 157 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

GABPA 2 datasets

ChIP WA01 ENCSR000BIW.GABPA.WA01 474 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 282 bp overlap

GATA3 1 dataset

ChIP MCF-7 GSE128445.GATA3.MCF-7 277 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 474 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 428 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 340 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 377 bp overlap

ChIP WTC11 ENCFF506LYD 328 bp overlap

JARID2 6 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 846 bp overlap

ChIP EDOMIPS2 GSE48516.JARID2.EDOMIPS2 836 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 283 bp overlap

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 846 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 846 bp overlap

ChIP UTEIPS7 GSE48516.JARID2.UTEIPS7 846 bp overlap

ChIP MCF-7_TamR GSE128445.JUN.MCF-7_TamR 434 bp overlap

ChIP WTC11 ENCFF172UDA 361 bp overlap

KAT7 2 datasets

ChIP WTC11 ENCFF581TPB 414 bp overlap

ChIP WTC11 ENCFF581TPB 511 bp overlap

KDM4A 6 datasets

ChIP H1 ENCFF078LED 462 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 846 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 522 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 678 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 513 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 234 bp overlap

KDM5B 1 dataset

ChIP MCF-7 GSE46055.KDM5B.MCF-7 127 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 340 bp overlap

ChIP H1 ENCFF914VQY 270 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 335 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 219 bp overlap

ChIP WTC11 ENCFF223QFY 481 bp overlap

MBD2 2 datasets

ChIP HeLa GSE41006.MBD2.HeLa 222 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 178 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 370 bp overlap

MYBL2 1 dataset

ChIP WTC11 ENCFF166TKT 216 bp overlap

ChIP NCI-H128 GSE41105.MYC.NCI-H128 174 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 352 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 238 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 228 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 338 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 160 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 337 bp overlap

ChIP WTC11 ENCFF751ZTQ 372 bp overlap

NR2C2 1 dataset

ChIP WTC11 ENCFF896ODS 371 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 677 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 846 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 106 bp overlap

ChIP retina_Hu13 GSE137311.NRL.retina_Hu13 353 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 375 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 279 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 229 bp overlap

PCGF2 1 dataset

ChIP HEK293T_PCGF2fl GSE119618.PCGF2.HEK293T_PCGF2fl 307 bp overlap

POU5F1 8 datasets

ChIP BG03 GSE21614.POU5F1.BG03 146 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 118 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 143 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 846 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 266 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 351 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 368 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 148 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 754 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 175 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 397 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 284 bp overlap

ChIP WTC11 ENCFF874IIP 348 bp overlap

ChIP L1236 GSE63736.RELB.L1236 101 bp overlap

Motif ES_0h ES_0h-REST_MA0138.3 20 bp overlap

RNF2 5 datasets

ChIP H1 ENCFF239FFS 562 bp overlap

ChIP WA01 ENCSR784VUY.RNF2.WA01 324 bp overlap

ChIP WA01 GSE104690.RNF2.WA01 243 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 407 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 508 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 734 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 405 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 218 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 846 bp overlap

SIN3A 3 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 121 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 218 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 162 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 441 bp overlap

ChIP WTC11 ENCFF891HYW 377 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 446 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 239 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 403 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 183 bp overlap

SMAD4 1 dataset

ChIP WTC11 ENCFF195KVB 371 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 202 bp overlap

SMC1A 1 dataset

ChIP primary-epidermal-keratinocyte_diff_d0 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d0 348 bp overlap

SOX2 2 datasets

ChIP RENVM GSE49404.SOX2.RENVM 135 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 183 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 846 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 846 bp overlap

SSRP1 1 dataset

ChIP HT-1080_AclacinomycinA GSE107595.SSRP1.HT-1080_AclacinomycinA 239 bp overlap

STAT1 1 dataset

ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 140 bp overlap

STAT3 2 datasets

ChIP WA01 ERP004237.STAT3.WA01 185 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 377 bp overlap

SUZ12 17 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 846 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 846 bp overlap

ChIP H1 ENCFF881NFR 564 bp overlap

ChIP H1 ENCFF881NFR 362 bp overlap

ChIP H1 ENCFF881NFR 362 bp overlap

ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 373 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.SUZ12.HEK293T_PCGF135fl_OHT 373 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 363 bp overlap

ChIP HEK293T_PCGF2fl_OHT GSE119618.SUZ12.HEK293T_PCGF2fl_OHT 447 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 93 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 316 bp overlap

ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 84 bp overlap

ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 373 bp overlap

ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 198 bp overlap

ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 121 bp overlap

ChIP ProEs GSE59087.SUZ12.ProEs 96 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 363 bp overlap

TCF7 2 datasets

ChIP WTC11 ENCFF431UYL 403 bp overlap

ChIP breast-organoid_BRCA1-mut GSE113909.TCF7.breast-organoid_BRCA1-mut 389 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 214 bp overlap

TEAD4 1 dataset

ChIP WTC11 ENCFF114TZS 341 bp overlap

TFAP4::ETV1 1 dataset

Motif ES_0h ES_0h-TFAP4ETV1_MA1966.2 13 bp overlap

TFIIIC 2 datasets

ChIP HEK293 GSE119418.TFIIIC.HEK293 284 bp overlap

ChIP HEK293 GSE119418.TFIIIC.HEK293 310 bp overlap

TGIF2 1 dataset

ChIP WTC11 ENCFF649SHI 363 bp overlap

TP53 2 datasets

ChIP WTC11 ENCFF359JCU 425 bp overlap

ChIP WTC11 ENCFF359JCU 537 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 354 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 821 bp overlap

TRIM28 3 datasets

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 207 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 174 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 153 bp overlap

ChIP K-562 GSE111469.USF2.K-562 178 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 846 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 87 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 355 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 112 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 736 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 293 bp overlap

ZNF143 1 dataset

ChIP WTC11 ENCFF249JUK 382 bp overlap

ZNF184 2 datasets

ChIP WTC11 ENCFF352POG 441 bp overlap

ChIP WTC11 ENCFF352POG 497 bp overlap

ChIP HEK293T GSE78099.ZNF2.HEK293T 520 bp overlap

ZNF219 1 dataset

ChIP WTC11 ENCFF998WKU 386 bp overlap

ZNF28 2 datasets

ChIP HEK293T GSE78099.ZNF28.HEK293T 132 bp overlap

ChIP HEK293T GSE78099.ZNF28.HEK293T 283 bp overlap

ZNF317 1 dataset

ChIP WTC11 ENCFF537KXI 357 bp overlap

ZNF320 1 dataset

Motif ES_0h ES_0h-ZNF320_MA1976.2 20 bp overlap

ZNF454 1 dataset

Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap

ZNF519 1 dataset

ChIP HEK293T GSE78099.ZNF519.HEK293T 193 bp overlap

ZNF93 1 dataset

Motif ES_0h ES_0h-ZNF93_MA1721.2 14 bp overlap