chr11:46,664,502–46,665,016

chr11 : 46,664,502 – 46,665,016

514 bp 126 TFs 8 linked genes

This 514 bp open chromatin element is linked to 8 target genes and is bound by 126 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARHGAP1		35.8 kb	Distal	Multiome
ATG13		47.2 kb	Distal	Multiome
HARBI1		47.6 kb	Distal	Multiome
AMBRA1		70.7 kb	Distal	Multiome
CKAP5		181.5 kb	Distal	Multiome
LRP4		253.8 kb	Distal	Multiome
CSTPP1		272.0 kb	Distal	Multiome
MDK		283.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

126 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 324 bp overlap

ChIP K562 ENCFF938UXQ 505 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMSO GSE85096.ARNTL.U2OS_DMSO 303 bp overlap

ATF1 2 datasets

ChIP K-562 ENCSR091GVJ.ATF1.K-562 429 bp overlap

ChIP K562 ENCFF980NSF 251 bp overlap

BCL11A 1 dataset

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 102 bp overlap

BHLHE22 1 dataset

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

BHLHE40 1 dataset

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 118 bp overlap

BMPR1A 1 dataset

ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 252 bp overlap

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 208 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 367 bp overlap

BRD4 6 datasets

ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 413 bp overlap

ChIP K-562_JQ1_2h GSE99178.BRD4.K-562_JQ1_2h 135 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 271 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 441 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 180 bp overlap

ChIP OCI-AML3 GSE104745.BRD4.OCI-AML3 152 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 362 bp overlap

ChIP K562 ENCFF963TXY 374 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 361 bp overlap

ChIP K562 ENCFF673OEZ 198 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 134 bp overlap

ChIP K-562 ENCSR077DKV.CREM.K-562 123 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 506 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF364PUR 127 bp overlap

ChIP BLaER1 ENCFF896HSY 251 bp overlap

DACH1 2 datasets

ChIP K-562 ENCSR030TJP.DACH1.K-562 289 bp overlap

ChIP K562 ENCFF574LOW 362 bp overlap

DIDO1 1 dataset

ChIP K-562 ENCSR167JBG.DIDO1.K-562 231 bp overlap

DMRTC2 1 dataset

Motif DE_72h DE_72h-DMRTC2_MA1479.2 11 bp overlap

DPF2 4 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 441 bp overlap

ChIP K562 ENCFF739JDE 497 bp overlap

ChIP K562 ENCFF739JDE 310 bp overlap

ChIP K562 ENCFF775HUO 365 bp overlap

Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap

EGR1 6 datasets

ChIP K-562 ENCSR211LTF.EGR1.K-562 451 bp overlap

ChIP K-562 ENCSR024CNP.EGR1.K-562 420 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 211 bp overlap

ChIP K562 ENCFF006PJY 140 bp overlap

ChIP K562 ENCFF113OPQ 207 bp overlap

ChIP K562 ENCFF895KGN 248 bp overlap

EHMT2 2 datasets

ChIP K-562 ENCSR175EOM.EHMT2.K-562 223 bp overlap

ChIP K562 ENCFF053BWO 385 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 365 bp overlap

EP300 1 dataset

ChIP K-562 ENCSR000EGE.EP300.K-562 130 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 227 bp overlap

FOSL2 1 dataset

Motif DE_72h DE_72h-FOSL2_MA0478.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 417 bp overlap

ChIP DE DE-FOXA2-2 420 bp overlap

FOXJ2 1 dataset

ChIP K562 ENCFF457GZC 514 bp overlap

FOXK2 2 datasets

ChIP K-562 ENCSR508DQA.FOXK2.K-562 226 bp overlap

ChIP K562 ENCFF851PFH 423 bp overlap

GATA1 14 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 247 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 224 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 405 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 162 bp overlap

ChIP K-562 ENCSR000EWM.GATA1.K-562 214 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 322 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 372 bp overlap

ChIP K562 ENCFF876GFS 297 bp overlap

ChIP erythroblast ENCFF867JAR 514 bp overlap

ChIP erythroblast ENCFF867JAR 379 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 514 bp overlap

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 137 bp overlap

ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 214 bp overlap

ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 272 bp overlap

GATA2 6 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 147 bp overlap

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 359 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 209 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 205 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 159 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 425 bp overlap

ChIP DE DE-GATA4-2 484 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 514 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 514 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 405 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 453 bp overlap

ChIP DE DE-GATA6-2 488 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 427 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 267 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 272 bp overlap

ChIP foregut GSE117136.GATA6.foregut 478 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 366 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 479 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 465 bp overlap

GATAD2A 1 dataset

ChIP K562 ENCFF071LJW 345 bp overlap

GLYR1 1 dataset

ChIP HeLa GSE20303.GLYR1.HeLa 166 bp overlap

GTF2F1 1 dataset

ChIP K-562 ENCSR189VXS.GTF2F1.K-562 259 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC1 5 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 387 bp overlap

ChIP K-562 ENCSR711VWL.HDAC1.K-562 238 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 74 bp overlap

ChIP K562 ENCFF928TKZ 454 bp overlap

ChIP K562 ENCFF968WBH 484 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR563YDA.HDGF.K-562 453 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 305 bp overlap

Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap

Motif DE_72h DE_72h-Hic1_MA0739.2 8 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 514 bp overlap

IKZF1 3 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 514 bp overlap

ChIP K562 ENCFF348IBL 403 bp overlap

ChIP K562 ENCFF771OHZ 384 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 514 bp overlap

ChIP K-562 ENCSR000EGN.JUND.K-562 174 bp overlap

KLF11 1 dataset

Motif DE_72h DE_72h-KLF11_MA1512.2 10 bp overlap

KLF14 1 dataset

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap

Motif DE_72h DE_72h-KLF6_MA1517.2 9 bp overlap

L3MBTL2 2 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 463 bp overlap

ChIP K562 ENCFF320EQC 446 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 173 bp overlap

ChIP K562 ENCFF524IJO 397 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 194 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 273 bp overlap

MEF2D 1 dataset

ChIP K-562 ENCSR647ZXA.MEF2D.K-562 340 bp overlap

MLLT1 2 datasets

ChIP K-562 ENCSR107GRP.MLLT1.K-562 340 bp overlap

ChIP K562 ENCFF074XRJ 264 bp overlap

ChIP K-562 ENCSR512NLO.MNT.K-562 222 bp overlap

MTA2 4 datasets

ChIP K-562 ENCSR411UYA.MTA2.K-562 339 bp overlap

ChIP K-562 ENCSR113LAS.MTA2.K-562 224 bp overlap

ChIP K562 ENCFF441KCP 417 bp overlap

ChIP K562 ENCFF880VZB 341 bp overlap

MTA3 3 datasets

ChIP K-562 ENCSR180NCY.MTA3.K-562 387 bp overlap

ChIP K-562 ENCSR914NEI.MTA3.K-562 246 bp overlap

ChIP K562 ENCFF289UFB 378 bp overlap

Motif DE_72h DE_72h-MXI1_MA1108.3 6 bp overlap

ChIP K-562 ENCSR000EGJ.MYC.K-562 146 bp overlap

ChIP K-562 ENCSR000EZU.MYC.K-562 153 bp overlap

ChIP K-562 ENCSR000EGS.MYC.K-562 152 bp overlap

Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap

ChIP K-562 ENCSR085QEV.NBN.K-562 267 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 118 bp overlap

NFE2L2 1 dataset

ChIP K-562 ENCSR485GKE.NFE2L2.K-562 167 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 188 bp overlap

NR2C1 1 dataset

Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 367 bp overlap

NR2F2 2 datasets

ChIP K-562 ENCSR000BRS.NR2F2.K-562 260 bp overlap

ChIP K562 ENCFF004YPK 332 bp overlap

NR3C1 1 dataset

ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 158 bp overlap

NRF1 5 datasets

ChIP K-562 ENCSR494TDU.NRF1.K-562 371 bp overlap

ChIP K-562 ENCSR998AJK.NRF1.K-562 244 bp overlap

ChIP K562 ENCFF689EWI 320 bp overlap

ChIP K562 ENCFF689EWI 514 bp overlap

ChIP K562 ENCFF791UHF 455 bp overlap

Neurod2 1 dataset

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap

Olig2 1 dataset

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PKNOX1 1 dataset

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 267 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 343 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 224 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

RAD51 2 datasets

ChIP K-562 ENCSR524BUE.RAD51.K-562 493 bp overlap

ChIP K562 ENCFF133ELP 138 bp overlap

RBM39 2 datasets

ChIP K-562 ENCSR764OXF.RBM39.K-562 260 bp overlap

ChIP K-562 GSE120104.RBM39.K-562 238 bp overlap

ChIP K-562 ENCSR772EEN.RELA.K-562 406 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 218 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 284 bp overlap

SMARCA4 5 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 477 bp overlap

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 213 bp overlap

ChIP K562 ENCFF316MCJ 485 bp overlap

ChIP K562 ENCFF506JCB 200 bp overlap

ChIP K562 ENCFF506JCB 314 bp overlap

SMARCE1 2 datasets

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 351 bp overlap

ChIP K562 ENCFF690CFF 464 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 290 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 352 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 403 bp overlap

ChIP K562 ENCFF059YCJ 437 bp overlap

Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap

Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap

SREBF1 1 dataset

Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap

SREBF2 1 dataset

Motif DE_72h DE_72h-SREBF2_MA0828.3 10 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Stat4 1 dataset

Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap

TAL1 7 datasets

ChIP CD34 GSE52924.TAL1.CD34 134 bp overlap

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 365 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 223 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 194 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 193 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 195 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 207 bp overlap

ChIP K-562 ENCSR970OJY.TCF3.K-562 184 bp overlap

TFAP4 2 datasets

Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap

ChIP K562 ENCFF727PXG 426 bp overlap

THAP1 1 dataset

Motif DE_72h DE_72h-THAP1_MA0597.3 8 bp overlap

TRIM28 1 dataset

ChIP K-562 ENCSR474CVP.TRIM28.K-562 266 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Tcf12 1 dataset

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP K-562 ENCSR000EFZ.UBTF.K-562 212 bp overlap

USF1 4 datasets

ChIP K-562 ENCSR000BKT.USF1.K-562 392 bp overlap

ChIP K562 ENCFF202SFC 393 bp overlap

ChIP K562 ENCFF633EZB 67 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 156 bp overlap

USF2 2 datasets

ChIP K-562 ENCSR578KEN.USF2.K-562 142 bp overlap

ChIP K562 ENCFF397QGU 247 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 346 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 204 bp overlap

ChIP K-562 ENCSR000BKU.YY1.K-562 150 bp overlap

ChIP K-562 ENCSR000EWF.YY1.K-562 170 bp overlap

ChIP K562 ENCFF199FNC 331 bp overlap

ChIP K562 ENCFF660QRE 81 bp overlap

ChIP K562 ENCFF768DPZ 311 bp overlap

ZBTB1 2 datasets

ChIP Jurkat_ZBTB1-KO_Asp-deprivation_cDNA GSE145783.ZBTB1.Jurkat_ZBTB1-KO_Asp-deprivation_cDNA 156 bp overlap

ChIP Jurkat_ZBTB1-KO_cDNA GSE145783.ZBTB1.Jurkat_ZBTB1-KO_cDNA 156 bp overlap

ZBTB11 2 datasets

ChIP K-562 ENCSR706BJO.ZBTB11.K-562 228 bp overlap

ChIP K562 ENCFF215OUF 236 bp overlap

ZBTB17 1 dataset

ChIP K562 ENCFF731UTU 403 bp overlap

ZBTB7A 4 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 514 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 248 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 118 bp overlap

ChIP K562 ENCFF579ZGM 401 bp overlap

ZFP42 1 dataset

Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 145 bp overlap

ZNF395 1 dataset

ChIP K562 ENCFF464EIT 514 bp overlap

ZNF530 1 dataset

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF592 3 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 382 bp overlap

ChIP K562 ENCFF547OSS 514 bp overlap

ChIP K562 ENCFF547OSS 404 bp overlap

ZNF675 1 dataset

Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap

Zic1::Zic2 1 dataset

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap