chr8:41,567,337–41,567,862

chr8 : 41,567,337 – 41,567,862

525 bp 108 TFs 6 linked genes

This 525 bp open chromatin element is linked to 6 target genes and is bound by 108 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
GPAT4		10.7 kb	Distal	Multiome
GPAT4-AS1		10.9 kb	Distal	Multiome
GINS4		38.2 kb	Distal	Multiome
GOLGA7		76.9 kb	Distal	Multiome
ANK1		200.0 kb	Distal	Multiome
SFRP1		258.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

108 transcription factors

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 246 bp overlap

ChIP breast_tumor_Male_26 GSE104399.AR.breast_tumor_Male_26 138 bp overlap

ChIP myofibroblast GSE90772.AR.myofibroblast 185 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 468 bp overlap

ARNTL 1 dataset

ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 246 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 525 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 525 bp overlap

BACH1 2 datasets

ChIP H1 ENCFF282VDB 132 bp overlap

ChIP WA01 ENCSR000EBQ.BACH1.WA01 56 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 525 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 525 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 525 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 525 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 377 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 86 bp overlap

BRD4 9 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 402 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 178 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 136 bp overlap

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 313 bp overlap

ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 170 bp overlap

ChIP LNCaP-clone-FGC_DHT-Enzalutamide GSE118247.BRD4.LNCaP-clone-FGC_DHT-Enzalutamide 134 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD4.MV4-11_DMSO 130 bp overlap

ChIP hESC GSE33281.BRD4.hESC 98 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 197 bp overlap

CBFB 2 datasets

ChIP ME-1 GSE46044.CBFB.ME-1 445 bp overlap

ChIP SKNO-1 GSE23730.CBFB.SKNO-1 214 bp overlap

CEBPB 1 dataset

ChIP WA01 ENCSR000EBV.CEBPB.WA01 121 bp overlap

ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 166 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 94 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 54 bp overlap

ChIP WTC11 ENCFF209ZUE 184 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 433 bp overlap

CTCF 11 datasets

ChIP GM06077 GSE148179.CTCF.GM06077 177 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 137 bp overlap

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 314 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 386 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 525 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 232 bp overlap

ChIP T-47D_triptolide GSE111923.CTCF.T-47D_triptolide 350 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 79 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 162 bp overlap

ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 193 bp overlap

ChIP leukemia_CEBPA-96h GSE142161.CTCF.leukemia_CEBPA-96h 221 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 146 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF031ISE 280 bp overlap

ChIP BLaER1 ENCFF262VBH 353 bp overlap

ChIP BLaER1 ENCFF335XTP 196 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 177 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 525 bp overlap

ChIP ProEs GSE59087.EED.ProEs 525 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 125 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 174 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 396 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 225 bp overlap

ESR1 5 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 348 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 330 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 371 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 117 bp overlap

ChIP MDA-MB-231_LQ_45min GSE95121.ESR1.MDA-MB-231_LQ_45min 176 bp overlap

ESRRA 1 dataset

ChIP WTC11 ENCFF591YCA 350 bp overlap

ChIP WTC11 ENCFF812SCD 260 bp overlap

EZH2 15 datasets

ChIP DOHH2 ENCFF528GDC 243 bp overlap

ChIP H1 ENCFF232NZA 525 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 178 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 224 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 356 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 525 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 416 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 525 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 266 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 111 bp overlap

ChIP hESC GSE113817.EZH2.hESC 227 bp overlap

ChIP neural progenitor cell ENCFF018MKA 525 bp overlap

ChIP neural progenitor cell ENCFF018MKA 525 bp overlap

ChIP neural progenitor cell ENCFF472NFV 464 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 525 bp overlap

EZH2_phosphoT487 2 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 511 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 505 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 234 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 149 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 303 bp overlap

FOXP4 2 datasets

ChIP WTC11 ENCFF708TAF 161 bp overlap

ChIP WTC11 ENCFF708TAF 366 bp overlap

GABPA 1 dataset

ChIP H1 ENCFF739QFD 286 bp overlap

GATA2 1 dataset

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 141 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 517 bp overlap

GTF2F1 1 dataset

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 153 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 291 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF353UJQ 257 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 222 bp overlap

HIF1A 2 datasets

ChIP 501-mel GSE95280.HIF1A.501-mel 306 bp overlap

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 191 bp overlap

HMGN3 1 dataset

ChIP K-562 ENCSR000DOB.HMGN3.K-562 201 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 181 bp overlap

HNRNPLL 1 dataset

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 225 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 279 bp overlap

JARID2 3 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 347 bp overlap

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 343 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 466 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 193 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 525 bp overlap

ChIP GM23338 ENCFF224LRO 325 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 268 bp overlap

KDM4A 5 datasets

ChIP H1 ENCFF078LED 373 bp overlap

ChIP H1 ENCFF078LED 525 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 525 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 239 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 397 bp overlap

KDM5B 1 dataset

ChIP SUM159 GSE46055.KDM5B.SUM159 125 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 378 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 180 bp overlap

ChIP WTC11 ENCFF223QFY 311 bp overlap

ChIP WTC11 ENCFF223QFY 515 bp overlap

ChIP K-562 ENCSR221GAN.MBD2.K-562 119 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 324 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 375 bp overlap

MYBL2 1 dataset

ChIP WTC11 ENCFF166TKT 288 bp overlap

ChIP CD34 GSE85488.MYC.CD34 486 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 328 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 346 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 400 bp overlap

NOTCH1 1 dataset

ChIP HCC1599 GSE116871.NOTCH1.HCC1599 179 bp overlap

NR3C1 1 dataset

ChIP WTC11 ENCFF422OEM 357 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 430 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 400 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 280 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 359 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 525 bp overlap

PHF19 1 dataset

ChIP DU145_CTR GSE135623.PHF19.DU145_CTR 137 bp overlap

POLR2A 4 datasets

ChIP GM23338 ENCFF450WCS 322 bp overlap

ChIP GM23338 ENCFF450WCS 491 bp overlap

ChIP GM23338 ENCFF450WCS 270 bp overlap

ChIP H1 ENCFF566JSR 362 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 200 bp overlap

POU2F2 1 dataset

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 68 bp overlap

POU5F1 8 datasets

ChIP BG03 GSE21614.POU5F1.BG03 525 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 124 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 525 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 97 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 345 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 393 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 148 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 184 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 454 bp overlap

RAD21 1 dataset

ChIP hiPSC_IV8 GSE106870.RAD21.hiPSC_IV8 145 bp overlap

RBBP5 3 datasets

ChIP H1 ENCFF905HFL 448 bp overlap

ChIP H1 ENCFF905HFL 396 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 525 bp overlap

RNF2 4 datasets

ChIP WA01 ENCSR784VUY.RNF2.WA01 206 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 525 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 375 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 83 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 382 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 284 bp overlap

RUNX1 1 dataset

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 170 bp overlap

RUNX1T1 2 datasets

ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 156 bp overlap

ChIP Kasumi-1_E2 GSE102697.RUNX1T1.Kasumi-1_E2 153 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 321 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 525 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 315 bp overlap

SIN3A 4 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 292 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 137 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 245 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 208 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 127 bp overlap

SMARCA4 2 datasets

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 375 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 238 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 406 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 223 bp overlap

ChIP macrophage_IFNG GSE47188.SPI1.macrophage_IFNG 188 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 309 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 365 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 346 bp overlap

SUZ12 6 datasets

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 331 bp overlap

ChIP H1 ENCFF881NFR 525 bp overlap

ChIP H1 ENCFF881NFR 525 bp overlap

ChIP ProEs GSE59087.SUZ12.ProEs 245 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 525 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 471 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 313 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 467 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 378 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 312 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 196 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 161 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 311 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 376 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 363 bp overlap

ChIP NPC GSE154479.TCF3.NPC 493 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 525 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 382 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 404 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 247 bp overlap

TP53 3 datasets

ChIP WTC11 ENCFF359JCU 450 bp overlap

ChIP WTC11 ENCFF359JCU 234 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 140 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 128 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 335 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 414 bp overlap

ChIP WTC11 ENCFF699QGS 68 bp overlap

ChIP WTC11 ENCFF139JAW 93 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 407 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 525 bp overlap

ChIP K562 ENCFF427SDV 263 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 218 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 441 bp overlap

ZNF121 2 datasets

ChIP WTC11 ENCFF291API 141 bp overlap

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF138 1 dataset

ChIP WTC11 ENCFF800FUU 269 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 295 bp overlap