Involved in Golgi to plasma membrane protein transport; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Acts upstream of or within Golgi to plasma membrane transport. Located in Golgi membrane and Golgi stack. Part of palmitoyltransferase complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GOLGA7. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GOLGA7 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GOLGA7, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:41,276,067–41,276,631 | 214.1 kb | Distal (>10kb) Multiome | 97 | |
| chr8:41,308,199–41,310,004 | 181.1 kb | Distal (>10kb) Multiome | 268 | |
| chr8:41,341,689–41,343,004 | 148.2 kb | Distal (>10kb) Multiome | 138 | |
| chr8:41,360,734–41,361,748 | 129.4 kb | Distal (>10kb) Multiome | 214 | |
| chr8:41,489,933–41,491,073 | 78 bp | At TSS Multiome | 716 | |
| chr8:41,528,584–41,529,537 | 38.5 kb | Distal (>10kb) Multiome | 730 | |
| chr8:41,567,337–41,567,862 | 76.9 kb | Distal (>10kb) Multiome | 108 | |
| chr8:41,577,579–41,578,739 | 87.6 kb | Distal (>10kb) Multiome | 755 | |
| chr8:41,646,199–41,646,780 | 155.9 kb | Distal (>10kb) Multiome | 132 | |
| chr8:41,653,451–41,654,479 | 163.5 kb | Distal (>10kb) Multiome | 235 | |
| chr8:41,701,707–41,702,358 | 211.3 kb | Distal (>10kb) Multiome | 481 | |
| chr8:41,766,804–41,768,073 | 276.8 kb | Distal (>10kb) Multiome | 304 |
Genomic view of the GOLGA7 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.