chr19:55,095,398–55,095,977

chr19 : 55,095,398 – 55,095,977

579 bp 90 TFs 10 linked genes

This 579 bp open chromatin element is linked to 10 target genes and is bound by 90 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RDH13		32.7 kb	Distal	Multiome
TNNT1		53.4 kb	Distal	Multiome
TNNI3		61.0 kb	Distal	Multiome
PPP6R1		163.2 kb	Distal	Multiome
HSPBP1		184.5 kb	Distal	Multiome
BRSK1		188.2 kb	Distal	Multiome
KMT5C		244.0 kb	Distal	Multiome
TMEM238		288.5 kb	Distal	Multiome
RPL28		290.1 kb	Distal	Multiome
ISOC2		365.8 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

ChIP NALM-6 GSE93626.AATF.NALM-6 208 bp overlap

AFF1 2 datasets

ChIP K-562 ENCSR241LIH.AFF1.K-562 453 bp overlap

ChIP K562 ENCFF096RYC 412 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 110 bp overlap

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 353 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 247 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 152 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 220 bp overlap

BCOR 3 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 267 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 291 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 211 bp overlap

BMPR1A 1 dataset

ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 111 bp overlap

BRD4 4 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 206 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 210 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 270 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 246 bp overlap

CDK9 2 datasets

ChIP MM1-S_DMSO GSE42355.CDK9.MM1-S_DMSO 179 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 173 bp overlap

CDKN1B 2 datasets

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 175 bp overlap

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 123 bp overlap

CREBBP_M742 1 dataset

ChIP NCI-H3396_E2 GSE32349.CREBBP_M742.NCI-H3396_E2 98 bp overlap

ChIP K-562 ENCSR077DKV.CREM.K-562 170 bp overlap

CTCF 5 datasets

ChIP A-549 ENCSR000AUE.CTCF.A-549 256 bp overlap

ChIP A-549 ENCSR000AUF.CTCF.A-549 58 bp overlap

Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap

Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap

ChIP H1 ENCFF414GZI 217 bp overlap

DDX21 2 datasets

ChIP A-375 GSE128080.DDX21.A-375 295 bp overlap

ChIP A-375_1726plus GSE128080.DDX21.A-375_1726plus 280 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 217 bp overlap

ELF1 4 datasets

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 332 bp overlap

ChIP Hep-G2 ENCSR000BMZ.ELF1.Hep-G2 150 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 150 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

ESR1 8 datasets

ChIP Ishikawa ENCSR000BIY.ESR1.Ishikawa 165 bp overlap

ChIP Ishikawa ENCSR000BIZ.ESR1.Ishikawa 138 bp overlap

ChIP Ishikawa ENCSR000BKL.ESR1.Ishikawa 136 bp overlap

ChIP Ishikawa_E2 GSE109891.ESR1.Ishikawa_E2 142 bp overlap

ChIP Ishikawa_ETV4-OE GSE129803.ESR1.Ishikawa_ETV4-OE 335 bp overlap

ChIP MCF-7 GSE117492.ESR1.MCF-7 242 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 485 bp overlap

ChIP MCF-7_Veh_OA GSE93510.ESR1.MCF-7_Veh_OA 410 bp overlap

ETS1 6 datasets

ChIP A-549 ENCSR000BPU.ETS1.A-549 320 bp overlap

ChIP GM12878 ENCSR000BKA.ETS1.GM12878 126 bp overlap

ChIP GM23338 ENCFF701IZH 377 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 173 bp overlap

ChIP K-562 ENCSR000BKQ.ETS1.K-562 226 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 189 bp overlap

GABPA 9 datasets

ChIP A-549 ENCSR000BPY.GABPA.A-549 306 bp overlap

ChIP GM12878 ENCSR331HPA.GABPA.GM12878 120 bp overlap

ChIP HeLa-S3 ENCSR000BHS.GABPA.HeLa-S3 131 bp overlap

ChIP K-562 ENCSR000BLO.GABPA.K-562 263 bp overlap

ChIP K562 ENCFF996TSW 317 bp overlap

ChIP MCF-7 ENCSR000BUK.GABPA.MCF-7 125 bp overlap

ChIP SK-N-SH ENCSR000BTG.GABPA.SK-N-SH 147 bp overlap

ChIP VCaP_ETOH GSE49091.GABPA.VCaP_ETOH 173 bp overlap

ChIP VCaP_R1881 GSE49091.GABPA.VCaP_R1881 161 bp overlap

GABPB1 2 datasets

ChIP K-562 ENCSR138YYY.GABPB1.K-562 456 bp overlap

ChIP K562 ENCFF015GDS 360 bp overlap

GLIS2 2 datasets

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 97 bp overlap

ChIP HCT-116_DMSO GSE125927.GLIS2.HCT-116_DMSO 213 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 110 bp overlap

HCFC1 8 datasets

ChIP GM12878 ENCFF372SXO 331 bp overlap

ChIP GM12878 ENCSR514VAY.HCFC1.GM12878 244 bp overlap

ChIP HeLa-S3 ENCFF159VGJ 365 bp overlap

ChIP HeLa-S3 ENCSR000ECH.HCFC1.HeLa-S3 188 bp overlap

ChIP K-562 ENCSR000EFN.HCFC1.K-562 293 bp overlap

ChIP K562 ENCFF959WVM 218 bp overlap

ChIP MCF-7 ENCFF595ZTV 457 bp overlap

ChIP MCF-7 ENCSR697CUP.HCFC1.MCF-7 324 bp overlap

HOXC10 1 dataset

ChIP HEK293 ENCFF467BQB 175 bp overlap

IKZF2 1 dataset

Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap

ChIP K-562 ENCSR376WCJ.IRF2.K-562 174 bp overlap

JMJD1C 1 dataset

ChIP HL-60 GSE63484.JMJD1C.HL-60 246 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 184 bp overlap

ChIP MDA-BoM-1833_shp27 GSE112444.JUN.MDA-BoM-1833_shp27 217 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 104 bp overlap

KLF10 1 dataset

ChIP Hep-G2 GSE97661.KLF10.Hep-G2 236 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 399 bp overlap

KMT2B 1 dataset

ChIP AML_OG86 GSE112074.KMT2B.AML_OG86 190 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 103 bp overlap

ChIP K-562 ENCSR221GAN.MBD2.K-562 165 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 139 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 128 bp overlap

ChIP Kelly GSE138295.MYC.Kelly 417 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 52 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 579 bp overlap

NFKB1 3 datasets

ChIP HEK293T GSE129618.NFKB1.HEK293T 372 bp overlap

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 129 bp overlap

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 204 bp overlap

NOTCH1 2 datasets

ChIP CUTLL1 GSE29600.NOTCH1.CUTLL1 122 bp overlap

ChIP HPBALL GSE39263.NOTCH1.HPBALL 213 bp overlap

PATZ1 1 dataset

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 579 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 165 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 295 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 579 bp overlap

RAD21 1 dataset

ChIP HCT-116 GSE131606.RAD21.HCT-116 67 bp overlap

RBM22 4 datasets

ChIP K-562 GSE120104.RBM22.K-562 163 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 160 bp overlap

ChIP K-562 GSE120104.RBM22.K-562 177 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 169 bp overlap

ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 211 bp overlap

ChIP A-549 ENCSR000BQP.REST.A-549 184 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 69 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 145 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000BIS.SIN3A.WA01 107 bp overlap

SIX5 9 datasets

ChIP A-549 ENCSR000BRL.SIX5.A-549 399 bp overlap

ChIP GM12878 ENCFF766FEJ 123 bp overlap

ChIP GM12878 ENCSR000BJE.SIX5.GM12878 223 bp overlap

ChIP H1 ENCFF942SOJ 237 bp overlap

ChIP K-562 ENCSR000BGX.SIX5.K-562 198 bp overlap

ChIP K-562 ENCSR000BNW.SIX5.K-562 189 bp overlap

ChIP K562 ENCFF472MWE 251 bp overlap

ChIP K562 ENCFF637NIL 221 bp overlap

ChIP WA01 ENCSR000BIQ.SIX5.WA01 231 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 133 bp overlap

SMARCA4 1 dataset

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 103 bp overlap

SMARCC1 2 datasets

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 196 bp overlap

ChIP BIN-67 GSE117734.SMARCC1.BIN-67 175 bp overlap

ChIP HEK293 ENCFF181QXT 457 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 331 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 172 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 100 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 222 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 142 bp overlap

SRF 14 datasets

ChIP GM12878 ENCFF565AWY 201 bp overlap

ChIP GM12878 ENCFF878IIX 397 bp overlap

ChIP GM12878 ENCSR041XML.SRF.GM12878 330 bp overlap

ChIP GM12878 ENCSR000BMI.SRF.GM12878 138 bp overlap

ChIP H1 ENCFF036PEF 225 bp overlap

ChIP HCT-116 ENCSR000BSC.SRF.HCT-116 179 bp overlap

ChIP Hep-G2 ENCSR000BLV.SRF.Hep-G2 130 bp overlap

ChIP HepG2 ENCFF625QHW 185 bp overlap

ChIP Ishikawa ENCFF992QXM 305 bp overlap

ChIP Ishikawa ENCSR000BTD.SRF.Ishikawa 249 bp overlap

ChIP K-562 ENCSR000BLK.SRF.K-562 163 bp overlap

ChIP K-562 ENCSR582IAO.SRF.K-562 130 bp overlap

ChIP MCF-7 ENCSR000BVA.SRF.MCF-7 185 bp overlap

ChIP WA01 ENCSR000BIV.SRF.WA01 158 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 259 bp overlap

SUZ12 3 datasets

ChIP GM12878 ENCSR744XTG.SUZ12.GM12878 316 bp overlap

ChIP K-562 ENCSR412CTM.SUZ12.K-562 216 bp overlap

ChIP K562 ENCFF944TWT 265 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 124 bp overlap

TARDBP 1 dataset

ChIP K-562 ENCSR353HEP.TARDBP.K-562 124 bp overlap

TCF12 1 dataset

ChIP A-549 ENCSR000BQQ.TCF12.A-549 238 bp overlap

TFAP2C 4 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 307 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 112 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 139 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 235 bp overlap

THAP11 2 datasets

ChIP HEK293 GSE138205.THAP11.HEK293 579 bp overlap

ChIP HepG2 ENCFF272SWH 198 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 158 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 146 bp overlap

ZBTB10 1 dataset

ChIP HEK293 ENCSR004PLU.ZBTB10.HEK293 190 bp overlap

ZBTB11 4 datasets

ChIP HEK293 ENCFF262GZJ 475 bp overlap

ChIP HEK293 ENCSR882ZTS.ZBTB11.HEK293 248 bp overlap

ChIP K-562 ENCSR331GDC.ZBTB11.K-562 228 bp overlap

ChIP K562 ENCFF648EZG 425 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 274 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 260 bp overlap

ZBTB48 2 datasets

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 106 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 58 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 189 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 91 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 268 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 192 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 214 bp overlap

ZNF143 20 datasets

ChIP CUTLL1 GSE29600.ZNF143.CUTLL1 354 bp overlap

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 240 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 171 bp overlap

ChIP GM12878 ENCSR936XTK.ZNF143.GM12878 472 bp overlap

ChIP GM12878 ENCSR000DZL.ZNF143.GM12878 259 bp overlap

ChIP HEK293T GSE39263.ZNF143.HEK293T 374 bp overlap

ChIP HeLa GSE39263.ZNF143.HeLa 334 bp overlap

ChIP HeLa-S3 ENCSR000ECO.ZNF143.HeLa-S3 201 bp overlap

ChIP Hep-G2 ENCSR080UEM.ZNF143.Hep-G2 419 bp overlap

ChIP Hep-G2 ENCSR101FJT.ZNF143.Hep-G2 177 bp overlap

ChIP HepG2 ENCFF658YIR 148 bp overlap

ChIP K-562 GSE39263.ZNF143.K-562 309 bp overlap

ChIP K-562 ENCSR000EGP.ZNF143.K-562 308 bp overlap

ChIP K562 ENCFF554TVF 521 bp overlap

ChIP MCF-7 GSE76454.ZNF143.MCF-7 579 bp overlap

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 504 bp overlap

ChIP WA01 ENCSR000EBW.ZNF143.WA01 403 bp overlap

ChIP WA09 GSE105028.ZNF143.WA09 525 bp overlap

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 525 bp overlap

ChIP WTC11 ENCFF249JUK 196 bp overlap

ZNF281 1 dataset

ChIP K-562 GSE121133.ZNF281.K-562 116 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 426 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 421 bp overlap

ZNF341 3 datasets

ChIP HEK293 ENCFF944VMC 321 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 335 bp overlap

ChIP HEK293 GSE76494.ZNF341.HEK293 232 bp overlap

ZNF449 1 dataset

Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 405 bp overlap

ZNF506 1 dataset

ChIP HEK293T GSE78099.ZNF506.HEK293T 279 bp overlap

ZNF554 1 dataset

ChIP HEK293 GSE76494.ZNF554.HEK293 147 bp overlap

ZNF574 1 dataset

ChIP HEK293 GSE76494.ZNF574.HEK293 146 bp overlap

ZNF649 1 dataset

ChIP HEK293T GSE78099.ZNF649.HEK293T 313 bp overlap

ZNF682 1 dataset

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

ZNF76 3 datasets

ChIP HEK293 ENCFF374TCG 451 bp overlap

ChIP HEK293 ENCSR072LQF.ZNF76.HEK293 331 bp overlap

ChIP HEK293 GSE76494.ZNF76.HEK293 160 bp overlap

ZSCAN4 2 datasets

ChIP HEK293 ENCFF381BKT 451 bp overlap

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 418 bp overlap