ZNF341

zinc finger protein 341 | dJ553F4.3

Enables DNA binding activity and DNA-binding transcription activator activity. Predicted to be involved in regulation of DNA-templated transcription. Located in nucleus. Implicated in hyper IgE recurrent infection syndrome 3. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 13 terms

DNA binding (GO:0003677)DNA binding (GO:0003677)DNA-binding transcription activator activity (GO:0001216)DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)nucleus (GO:0005634)nucleus (GO:0005634)nucleus (GO:0005634)positive regulation of DNA-templated transcription (GO:0045893)protein binding (GO:0005515)regulation of DNA-templated transcription (GO:0006355)regulation of transcription by RNA polymerase II (GO:0006357)

Expression (TPM)

TFs regulating ZNF341 0 TFs

Transcription factors with Perturb-seq knockdown data for ZNF341. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF341 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to ZNF341

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF341, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr20:33,443,149–33,444,777	288.1 kb	Distal (>10kb) Multiome	726
chr20:33,475,400–33,476,091	256.2 kb	Distal (>10kb) Multiome	98
chr20:33,477,323–33,477,813	254.4 kb	Distal (>10kb) Multiome	124
chr20:33,489,654–33,490,762	242.0 kb	Distal (>10kb) Multiome	1000
chr20:33,663,243–33,664,235	68.3 kb	Distal (>10kb) Multiome	895
chr20:33,666,358–33,668,405	65.2 kb	Distal (>10kb) Multiome	603
chr20:33,673,732–33,675,136	57.5 kb	Distal (>10kb) Multiome	826
chr20:33,685,755–33,686,963	45.5 kb	Distal (>10kb) Multiome	830
chr20:33,720,042–33,720,684	11.7 kb	Distal (>10kb) Multiome	584
chr20:33,731,496–33,732,906	131 bp	At TSS Multiome	1049
chr20:33,811,016–33,811,951	79.3 kb	Distal (>10kb) Multiome	921
chr20:33,992,591–33,994,776	261.4 kb	Distal (>10kb) Multiome	1067

Genome Browser

Genomic view of the ZNF341 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.