chr11:64,729,775–64,730,315

chr11 : 64,729,775 – 64,730,315

540 bp 115 TFs 10 linked genes

This 540 bp open chromatin element is linked to 10 target genes and is bound by 115 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NRXN2		6.6 kb	Proximal	Proximity
RASGRP2		14.8 kb	Distal	Multiome
SF1		48.8 kb	Distal	Multiome
MAP4K2		73.2 kb	Distal	Multiome
MEN1		80.7 kb	Distal	Multiome
EHD1		148.6 kb	Distal	Multiome
ATG2A		187.2 kb	Distal	Multiome
PPP2R5B		194.7 kb	Distal	Multiome
ARL2		284.1 kb	Distal	Multiome
SNX15		297.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

115 transcription factors

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 189 bp overlap

ChIP VCaP_DHT GSE79128.AR.VCaP_DHT 102 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 176 bp overlap

Ahr::Arnt 1 dataset

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 389 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 477 bp overlap

BRD4 3 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 215 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 386 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 276 bp overlap

ChIP Hep-G2 ENCSR819WZE.CBX1.Hep-G2 192 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.CDK9.MM1-S_JQ1_50NM 348 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 155 bp overlap

CTCF 3 datasets

ChIP MM1-S GSE43743.CTCF.MM1-S 324 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 130 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 245 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 64 bp overlap

ChIP U-87MG_GBM GSE99171.E2F1.U-87MG_GBM 139 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 234 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 133 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 320 bp overlap

ChIP K562 ENCFF006PJY 215 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 183 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 210 bp overlap

ESR1 4 datasets

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 204 bp overlap

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 101 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 160 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 79 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 127 bp overlap

EZH2 2 datasets

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 152 bp overlap

ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 171 bp overlap

FLI1 2 datasets

ChIP UAE GSE23730.FLI1.UAE 212 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 310 bp overlap

FOXA1 3 datasets

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 73 bp overlap

ChIP T-47D_JC4744 GSE126004.FOXA1.T-47D_JC4744 204 bp overlap

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 186 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 316 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 189 bp overlap

GTF2F1 2 datasets

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 305 bp overlap

ChIP K-562 GSE120104.GTF2F1.K-562 284 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 235 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 143 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 232 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 242 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 182 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 137 bp overlap

ChIP MCF-7_DMSO GSE157385.JUN.MCF-7_DMSO 390 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 198 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 260 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 95 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 249 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 138 bp overlap

KDM4A 3 datasets

ChIP H1 ENCFF078LED 501 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 239 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 261 bp overlap

KLF1 2 datasets

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

KLF10 2 datasets

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

KLF11 2 datasets

Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap

Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap

KLF12 2 datasets

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

KLF13 1 dataset

Motif DE_24h DE_24h-KLF13_MA0657.2 17 bp overlap

KLF14 2 datasets

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap

KLF16 2 datasets

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

KLF2 2 datasets

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

KLF3 3 datasets

Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap

Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 454 bp overlap

Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap

KLF5 3 datasets

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

ChIP ESO-26 GSE132680.KLF5.ESO-26 249 bp overlap

Motif DE_24h DE_24h-KLF6_MA1517.2 9 bp overlap

KLF7 2 datasets

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

KLF9 2 datasets

Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 171 bp overlap

KMT2A 1 dataset

ChIP OCI-AML-3_DMSO GSE129636.KMT2A.OCI-AML-3_DMSO 422 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 163 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 204 bp overlap

ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 199 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 169 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 286 bp overlap

MED26 1 dataset

ChIP HCT-116_aux GSE121355.MED26.HCT-116_aux 505 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 190 bp overlap

ChIP CD34 GSE85488.MYC.CD34 113 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 306 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 193 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 245 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 90 bp overlap

NELFE 3 datasets

ChIP HeLa GSE125534.NELFE.HeLa 231 bp overlap

ChIP K-562_HS GSE112379.NELFE.K-562_HS 211 bp overlap

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 152 bp overlap

NEUROD1 2 datasets

ChIP K-562 ENCSR986CDX.NEUROD1.K-562 121 bp overlap

ChIP K-562 ENCSR986CDX.NEUROD1.K-562 115 bp overlap

NFKB1 2 datasets

ChIP HEK293T GSE129618.NFKB1.HEK293T 268 bp overlap

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 327 bp overlap

ChIP T-47D_HAEGIN2 GSE59935.NRF1.T-47D_HAEGIN2 201 bp overlap

PATZ1 2 datasets

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 237 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 331 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 134 bp overlap

POLR2A 4 datasets

ChIP GM23338 ENCFF450WCS 125 bp overlap

ChIP H1 ENCFF566JSR 519 bp overlap

ChIP spleen ENCFF706IUS 328 bp overlap

ChIP spleen ENCFF706IUS 348 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 179 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 166 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 375 bp overlap

PRDM10 3 datasets

ChIP HEK293 ENCFF145WQQ 350 bp overlap

ChIP K-562 ENCSR120MPG.PRDM10.K-562 250 bp overlap

ChIP K562 ENCFF740YLK 370 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 343 bp overlap

RBM39 1 dataset

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 186 bp overlap

RUNX1 3 datasets

ChIP AML GSE111821.RUNX1.AML 211 bp overlap

ChIP SKH1_10d GSE87283.RUNX1.SKH1_10d 335 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 402 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE43834.RUNX1T1.Kasumi-1 148 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 283 bp overlap

SMARCA4 2 datasets

ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 169 bp overlap

ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 218 bp overlap

SMARCB1 4 datasets

ChIP MCF-7 GSE123284.SMARCB1.MCF-7 269 bp overlap

ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 436 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.SMARCB1.MCF-7_Fulvestrant 380 bp overlap

ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 296 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 178 bp overlap

ChIP HEK293T ERP007114.SP1.HEK293T 440 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 287 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

ChIP HEK293 ENCFF181QXT 229 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 330 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 230 bp overlap

ChIP HEK293T ERP007114.SP2.HEK293T 201 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 280 bp overlap

Motif DE_24h DE_24h-SP8_MA0747.2 11 bp overlap

Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap

Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 229 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 192 bp overlap

STAT3 16 datasets

ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 471 bp overlap

ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 496 bp overlap

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 467 bp overlap

ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 432 bp overlap

ChIP MCF-7_jc5848 GSE126004.STAT3.MCF-7_jc5848 513 bp overlap

ChIP T-47D_JC4735 GSE126004.STAT3.T-47D_JC4735 384 bp overlap

ChIP T-47D_JC4739 GSE126004.STAT3.T-47D_JC4739 281 bp overlap

ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 338 bp overlap

ChIP T-47D_JC4751 GSE126004.STAT3.T-47D_JC4751 426 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 510 bp overlap

ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 488 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 524 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 514 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 500 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 456 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 182 bp overlap

SUPT5H 2 datasets

ChIP HEK293_PNUTS GSE134198.SUPT5H.HEK293_PNUTS 212 bp overlap

ChIP HeLa GSE125534.SUPT5H.HeLa 197 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 319 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 482 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 447 bp overlap

ChIP hESC GSE122298.TBP.hESC 218 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 131 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 254 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 119 bp overlap

TFAP2A 1 dataset

ChIP MCF-7_E2 GSE60270.TFAP2A.MCF-7_E2 117 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 319 bp overlap

TFAP2C 2 datasets

ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 208 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 415 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 317 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 127 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 196 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 256 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 329 bp overlap

ZBED4 1 dataset

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF427SDV 170 bp overlap

ZBTB7A 2 datasets

ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 332 bp overlap

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 229 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 153 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 224 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 131 bp overlap

ZNF143 1 dataset

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 158 bp overlap

ZNF148 2 datasets

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF18 1 dataset

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 211 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 91 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 124 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 84 bp overlap

ZNF440 1 dataset

ChIP HEK293T GSE78099.ZNF440.HEK293T 407 bp overlap

ZNF558 1 dataset

ChIP HEK293T GSE78099.ZNF558.HEK293T 258 bp overlap

ZNF682 1 dataset

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 470 bp overlap

ZNF737 1 dataset

ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 69 bp overlap