chr7:44,063,611–44,064,251

chr7 : 44,063,611 – 44,064,251

640 bp 121 TFs 10 linked genes

This 640 bp open chromatin element is linked to 10 target genes and is bound by 121 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000239775		656 bp	At TSS	Proximity
PGAM2		1.3 kb	Proximal	Proximity
POLM		18.5 kb	Distal	Multiome
DBNL		19.3 kb	Distal	Multiome
AEBP1		40.3 kb	Distal	Multiome
POLD2		59.5 kb	Distal	Multiome
YKT6		137.0 kb	Distal	Multiome+HiCAR
UBE2D4		137.6 kb	Distal	Multiome
URGCP		157.4 kb	Distal	Multiome
MRPS24		194.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

121 transcription factors

AGO1 4 datasets

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 367 bp overlap

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 365 bp overlap

ChIP K562 ENCFF025NLP 609 bp overlap

ChIP K562 ENCFF741BCI 605 bp overlap

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 403 bp overlap

ChIP HepG2 ENCFF773YDL 406 bp overlap

ARID2 2 datasets

ChIP Aska-SS GSE108025.ARID2.Aska-SS 463 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 633 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 277 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 298 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 173 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 184 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 425 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 211 bp overlap

BRD4 4 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 223 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 417 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 66 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 88 bp overlap

ChIP WTC11 ENCFF113HIY 483 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 608 bp overlap

ChIP K-562 ENCSR000EHD.CHD2.K-562 168 bp overlap

CREB1 1 dataset

ChIP A-549 ENCSR000BRB.CREB1.A-549 179 bp overlap

CTCF 3 datasets

ChIP Hep-G2 ENCSR000BIE.CTCF.Hep-G2 106 bp overlap

ChIP HepG2 ENCFF757EKU 290 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 154 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 114 bp overlap

DDX5 2 datasets

ChIP BT-549 GSE112961.DDX5.BT-549 157 bp overlap

ChIP BT-549 GSE112961.DDX5.BT-549 229 bp overlap

E2F6 2 datasets

ChIP WA01 ENCSR000BSI.E2F6.WA01 207 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 108 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 310 bp overlap

ELF1 2 datasets

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 147 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 83 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 245 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 208 bp overlap

EZH2 3 datasets

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 483 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 640 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 545 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 210 bp overlap

FOSL2 2 datasets

ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 267 bp overlap

ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 94 bp overlap

HDAC2 1 dataset

ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 138 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 299 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 342 bp overlap

HNF4A 2 datasets

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 172 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 140 bp overlap

HNF4G 1 dataset

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 130 bp overlap

HNRNPH1 3 datasets

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 205 bp overlap

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 249 bp overlap

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 247 bp overlap

HNRNPL 2 datasets

ChIP Hep-G2 GSE120104.HNRNPL.Hep-G2 387 bp overlap

ChIP Hep-G2 ENCSR315JJE.HNRNPL.Hep-G2 184 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 587 bp overlap

ChIP MDA-BoM-1833_shp27 GSE112444.JUN.MDA-BoM-1833_shp27 448 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 640 bp overlap

ChIP HAEC GSE89970.JUNB.HAEC 352 bp overlap

JUND 3 datasets

ChIP A-549 ENCSR000BRF.JUND.A-549 137 bp overlap

ChIP H1 ENCFF468JZD 185 bp overlap

ChIP Hep-G2 ENCSR000BGK.JUND.Hep-G2 197 bp overlap

KDM2A 1 dataset

ChIP HepG2 ENCFF491GTR 181 bp overlap

KDM3A 1 dataset

ChIP Hep-G2 ENCSR387JKT.KDM3A.Hep-G2 194 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 114 bp overlap

Motif ES_0h ES_0h-KLF3_MA1516.2 10 bp overlap

KLF4 3 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 143 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 195 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 194 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 242 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 245 bp overlap

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 148 bp overlap

ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 162 bp overlap

ChIP WTC11 ENCFF223QFY 563 bp overlap

MEIS1 1 dataset

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 353 bp overlap

ChIP GM12878 ENCSR000BRH.MTA3.GM12878 211 bp overlap

MYBL2 4 datasets

ChIP A-673 GSE119971.MYBL2.A-673 531 bp overlap

ChIP MCF-10A_DOX GSE115787.MYBL2.MCF-10A_DOX 229 bp overlap

ChIP MCF-10A_ctrl GSE115787.MYBL2.MCF-10A_ctrl 452 bp overlap

ChIP WTC11 ENCFF166TKT 118 bp overlap

MYNN 3 datasets

ChIP K-562 ENCSR737LTZ.MYNN.K-562 128 bp overlap

ChIP K-562 ENCSR737LTZ.MYNN.K-562 229 bp overlap

ChIP K-562 ENCSR737LTZ.MYNN.K-562 67 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 285 bp overlap

Msgn1 1 dataset

Motif ES_0h ES_0h-Msgn1_MA1524.3 10 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 265 bp overlap

NCAPH2 2 datasets

ChIP IMR-90_Bethyl275_OIS GSE118494.NCAPH2.IMR-90_Bethyl275_OIS 580 bp overlap

ChIP IMR-90_FLAG_G GSE118494.NCAPH2.IMR-90_FLAG_G 261 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 394 bp overlap

NFKB1 2 datasets

ChIP HEK293T GSE129618.NFKB1.HEK293T 59 bp overlap

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 246 bp overlap

NR3C1 1 dataset

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 382 bp overlap

NR4A1 1 dataset

ChIP Kasumi-1 GSE79491.NR4A1.Kasumi-1 167 bp overlap

OGG1 2 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 386 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 330 bp overlap

ChIP retina_pigment GSE60024.PAX6.retina_pigment 214 bp overlap

PBX3 2 datasets

ChIP A-549 ENCSR000BTN.PBX3.A-549 102 bp overlap

Motif ES_0h ES_0h-PBX3_MA1114.2 11 bp overlap

PKNOX1 1 dataset

Motif ES_0h ES_0h-PKNOX1_MA0782.3 10 bp overlap

ChIP GM12878 ENCSR000BQM.PML.GM12878 401 bp overlap

POLR2A 20 datasets

ChIP GM12891 ENCFF379FCI 501 bp overlap

ChIP GM12892 ENCFF245LYF 484 bp overlap

ChIP GM12892 ENCFF245LYF 176 bp overlap

ChIP GM12892 ENCFF506PGQ 181 bp overlap

ChIP GM12892 ENCFF542ZFO 545 bp overlap

ChIP GM12892 ENCFF542ZFO 342 bp overlap

ChIP GM18951 ENCFF079KKO 331 bp overlap

ChIP GM19099 ENCFF726IBN 347 bp overlap

ChIP HCT116 ENCFF508RDJ 465 bp overlap

ChIP HCT116 ENCFF508RDJ 161 bp overlap

ChIP HL-60 ENCFF321XKE 505 bp overlap

ChIP HepG2 ENCFF736SLT 457 bp overlap

ChIP HepG2 ENCFF736SLT 393 bp overlap

ChIP K562 ENCFF836GHX 352 bp overlap

ChIP PFSK-1 ENCFF576NIT 221 bp overlap

ChIP Panc1 ENCFF290KAB 327 bp overlap

ChIP endothelial cell of umbilical vein ENCFF131DWO 68 bp overlap

ChIP spleen ENCFF044PYR 617 bp overlap

ChIP spleen ENCFF446ZGT 640 bp overlap

ChIP spleen ENCFF706IUS 640 bp overlap

POLR2G 4 datasets

ChIP HepG2 ENCFF241AEG 556 bp overlap

ChIP HepG2 ENCFF508UTS 326 bp overlap

ChIP K562 ENCFF047BLG 448 bp overlap

ChIP K562 ENCFF648YPL 513 bp overlap

POU2F1 2 datasets

ChIP T-47D GSE148277.POU2F1.T-47D 197 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 312 bp overlap

POU5F1 8 datasets

ChIP BG03 GSE21614.POU5F1.BG03 323 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 624 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 614 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 350 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 422 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 394 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 426 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 206 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 538 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 461 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 461 bp overlap

RBM22 3 datasets

ChIP HepG2 ENCFF292RVQ 192 bp overlap

ChIP K-562 GSE120104.RBM22.K-562 378 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 191 bp overlap

RBM39 4 datasets

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 321 bp overlap

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 289 bp overlap

ChIP HepG2 ENCFF084YZE 640 bp overlap

ChIP HepG2 ENCFF801JUH 640 bp overlap

ChIP Ramos GSE139810.REL.Ramos 266 bp overlap

RELA 2 datasets

ChIP 786-O GSE86092.RELA.786-O 94 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 317 bp overlap

REST 2 datasets

ChIP H1 ENCFF203SWY 102 bp overlap

ChIP K562 ENCFF758CZL 119 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 640 bp overlap

RUNX1 2 datasets

ChIP Jurkat GSE85524.RUNX1.Jurkat 348 bp overlap

ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 191 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 328 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 198 bp overlap

SIRT6 1 dataset

ChIP K-562 ENCSR000AUB.SIRT6.K-562 213 bp overlap

SIX1 2 datasets

ChIP Hep-G2 ENCSR561BQM.SIX1.Hep-G2 187 bp overlap

ChIP HepG2 ENCFF587VYG 249 bp overlap

SIX2 3 datasets

ChIP HEK GSE73865.SIX2.HEK 176 bp overlap

ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 125 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 175 bp overlap

SMAD5 1 dataset

ChIP GM12878 ENCSR251OVJ.SMAD5.GM12878 313 bp overlap

SMAD7 1 dataset

ChIP HepG2 ENCFF850FXR 446 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 207 bp overlap

SMARCB1 1 dataset

ChIP HeLa-S3 ENCSR000EDK.SMARCB1.HeLa-S3 175 bp overlap

ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 249 bp overlap

SOX2 2 datasets

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 257 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 297 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 172 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 213 bp overlap

SRSF3 1 dataset

ChIP Hep-G2 GSE120104.SRSF3.Hep-G2 412 bp overlap

STAG2 1 dataset

ChIP HCAEC GSE101921.STAG2.HCAEC 132 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 182 bp overlap

SUPT5H 4 datasets

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 425 bp overlap

ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 383 bp overlap

ChIP U2OS_siMYC GSE115365.SUPT5H.U2OS_siMYC 192 bp overlap

ChIP U2OS_siMYC_ON GSE115365.SUPT5H.U2OS_siMYC_ON 149 bp overlap

ChIP H1 ENCFF478SZO 402 bp overlap

TAF15 6 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 297 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 295 bp overlap

ChIP HepG2 ENCFF116QSW 497 bp overlap

ChIP HepG2 ENCFF116QSW 322 bp overlap

ChIP HepG2 ENCFF406BOT 481 bp overlap

ChIP HepG2 ENCFF406BOT 314 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 131 bp overlap

TBX18 1 dataset

Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap

TCF7L2 3 datasets

ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 172 bp overlap

ChIP Hep-G2 ENCSR346BOD.TCF7L2.Hep-G2 209 bp overlap

ChIP HepG2 ENCFF510OLG 346 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 344 bp overlap

TFDP2 1 dataset

ChIP Hep-G2 ENCSR069JKP.TFDP2.Hep-G2 202 bp overlap

ChIP MDA-MB-231 GSE95303.TP53.MDA-MB-231 63 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 102 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 286 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 76 bp overlap

ZBED4 1 dataset

Motif ES_0h ES_0h-ZBED4_MA2328.1 10 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 354 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 112 bp overlap

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 346 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 248 bp overlap

ChIP MCF-7 ENCFF009NAJ 481 bp overlap

ChIP MCF-7 GSE102616.ZFX.MCF-7 356 bp overlap

ZNF263 2 datasets

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 184 bp overlap

ChIP HepG2 ENCFF626SSV 271 bp overlap

ZNF274 1 dataset

ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 234 bp overlap

ZNF282 1 dataset

ChIP K-562 ENCSR742TMU.ZNF282.K-562 105 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 494 bp overlap

ZNF460 3 datasets

Motif ES_0h ES_0h-ZNF460_MA1596.1 16 bp overlap

ChIP HepG2 ENCFF007NNM 54 bp overlap

ChIP HepG2 ENCFF007NNM 253 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 299 bp overlap

ZNF574 1 dataset

Motif ES_0h ES_0h-ZNF574_MA1982.2 14 bp overlap

ZNF598 1 dataset

ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 381 bp overlap

ZNF610 1 dataset

Motif ES_0h ES_0h-ZNF610_MA1713.2 10 bp overlap

ZNF692 1 dataset

Motif ES_0h ES_0h-ZNF692_MA1986.2 8 bp overlap

ZNF711 1 dataset

ChIP HEK293T_22Rv1 GSE145160.ZNF711.HEK293T_22Rv1 289 bp overlap

ZNF883 1 dataset

ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 296 bp overlap

ZSCAN25 1 dataset

ChIP HepG2 ENCFF265FLD 141 bp overlap

Zbtb2 1 dataset

Motif ES_0h ES_0h-Zbtb2_MA2340.1 10 bp overlap

Motif ES_0h ES_0h-Zfx_MA0146.3 10 bp overlap