chr13:45,048,778–45,049,467

chr13 : 45,048,778 – 45,049,467

689 bp 140 TFs 5 linked genes

This 689 bp open chromatin element is linked to 5 target genes and is bound by 140 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
GPALPP1		59.6 kb	Distal	Multiome
NUFIP1		59.7 kb	Distal	Multiome
GTF2F2		71.3 kb	Distal	Multiome
TPT1		292.0 kb	Distal	Multiome+HiCAR
TPT1-AS1		292.2 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

140 transcription factors

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 260 bp overlap

ChIP UM-RC-6_empty-vector GSE101987.BAP1.UM-RC-6_empty-vector 89 bp overlap

ChIP GM12878 ENCFF954REE 143 bp overlap

BATF3 2 datasets

ChIP GM12878 GSE97661.BATF3.GM12878 265 bp overlap

ChIP KK-1_BirA GSE94732.BATF3.KK-1_BirA 195 bp overlap

BCL11A 1 dataset

ChIP GM12878 ENCSR000BHA.BCL11A.GM12878 131 bp overlap

BCL11B 2 datasets

ChIP HEK293 ENCFF859UHP 371 bp overlap

ChIP HEK293 ENCSR770PQN.BCL11B.HEK293 248 bp overlap

ChIP B-cell_GERMINAL_CENTER GSE43350.BCL6.B-cell_GERMINAL_CENTER 282 bp overlap

BHLHE40 4 datasets

ChIP GM12878 ENCFF010ZUU 331 bp overlap

ChIP GM12878 ENCFF521IZR 279 bp overlap

ChIP GM12878 ENCSR517QHU.BHLHE40.GM12878 474 bp overlap

ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 421 bp overlap

CDK9 2 datasets

ChIP MOLT-4_DMSO GSE79288.CDK9.MOLT-4_DMSO 363 bp overlap

ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 419 bp overlap

ChIP GM12878 ENCSR839XZU.CREM.GM12878 144 bp overlap

ChIP colon_transverse ENCSR102CSD.CTCF.colon_transverse 202 bp overlap

DPF2 2 datasets

ChIP GM12878 ENCFF681AJV 514 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 503 bp overlap

ChIP ProEs GSE59087.EED.ProEs 158 bp overlap

ChIP GM12878 ENCSR841NDX.ELF1.GM12878 212 bp overlap

ChIP PDAC GSE64557.ELF3.PDAC 345 bp overlap

ELK1::HOXB13 1 dataset

Motif DE_36h DE_36h-ELK1HOXB13_MA1932.2 15 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 302 bp overlap

EP300 2 datasets

ChIP neural ENCSR843ZUP.EP300.neural 266 bp overlap

ChIP neural cell ENCFF442QNK 446 bp overlap

ERF::HOXB13 1 dataset

Motif DE_36h DE_36h-ERFHOXB13_MA1937.2 13 bp overlap

ChIP Ishikawa_E2_D538G GSE132426.ESR1.Ishikawa_E2_D538G 442 bp overlap

ESRRA 1 dataset

ChIP K-562 ENCSR486IFJ.ESRRA.K-562 71 bp overlap

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 294 bp overlap

ETV6 2 datasets

ChIP GM12878 ENCSR626VUC.ETV6.GM12878 409 bp overlap

ChIP GM12878 GSE97661.ETV6.GM12878 288 bp overlap

FEZF1 3 datasets

ChIP HEK293 ENCFF528YED 411 bp overlap

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 497 bp overlap

ChIP HEK293 GSE76494.FEZF1.HEK293 417 bp overlap

FIGLA 1 dataset

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 200 bp overlap

FOXA1 1 dataset

Motif DE_36h DE_36h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 655 bp overlap

ChIP DE DE-FOXA2-2 689 bp overlap

Motif DE_36h DE_36h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_36h DE_36h-FOXA3_MA1683.2 7 bp overlap

FOXD1 1 dataset

Motif DE_36h DE_36h-FOXD1_MA0031.2 7 bp overlap

FOXG1 1 dataset

Motif DE_36h DE_36h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_36h DE_36h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_36h DE_36h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_36h DE_36h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_36h DE_36h-FOXL1_MA0033.2 7 bp overlap

FOXN3 1 dataset

Motif DE_36h DE_36h-FOXN3_MA1489.1 8 bp overlap

FOXO4 1 dataset

Motif DE_36h DE_36h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_36h DE_36h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_36h DE_36h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_36h DE_36h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_36h DE_36h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_36h DE_36h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_36h DE_36h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_36h DE_36h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_36h DE_36h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif DE_36h DE_36h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_36h DE_36h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_36h DE_36h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_36h DE_36h-Foxq1_MA0040.2 10 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 239 bp overlap

GATA2 2 datasets

ChIP LNCaP GSE38391.GATA2.LNCaP 69 bp overlap

ChIP LNCaP GSE52725.GATA2.LNCaP 69 bp overlap

GATA3 2 datasets

ChIP CD4_TH2 GSE72266.GATA3.CD4_TH2 295 bp overlap

ChIP Jurkat GSE76181.GATA3.Jurkat 473 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 662 bp overlap

ChIP DE DE-GATA4-2 685 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 223 bp overlap

ChIP foregut GSE117136.GATA4.foregut 547 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 689 bp overlap

ChIP DE DE-GATA6-2 656 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 618 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 654 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 543 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 689 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 642 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 568 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 574 bp overlap

ChIP foregut GSE117136.GATA6.foregut 484 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 341 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 459 bp overlap

HOXB8 1 dataset

ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 276 bp overlap

HOXC12 1 dataset

Motif DE_36h DE_36h-HOXC12_MA0906.2 10 bp overlap

HOXD12::ELK1 1 dataset

Motif DE_36h DE_36h-HOXD12ELK1_MA1958.2 13 bp overlap

IKZF1 2 datasets

ChIP GM12878 ENCFF753XDO 175 bp overlap

ChIP GM12878 ENCFF824TGK 245 bp overlap

IKZF2 4 datasets

ChIP GM12878 ENCFF238LYK 544 bp overlap

ChIP GM12878 ENCFF918AID 551 bp overlap

ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 380 bp overlap

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 396 bp overlap

IKZF3 2 datasets

ChIP HEK293 ENCFF518OXG 371 bp overlap

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 236 bp overlap

IRF4 4 datasets

ChIP B-cell GSE142493.IRF4.B-cell 292 bp overlap

ChIP GM12878 ENCFF769ZDL 321 bp overlap

ChIP GM12878 ENCSR000BGY.IRF4.GM12878 275 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 689 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 259 bp overlap

ChIP T-cell GSE136853.JUN.T-cell 309 bp overlap

JUNB 2 datasets

ChIP GM12878 ENCFF667EJQ 205 bp overlap

ChIP GM12878 ENCSR897MMC.JUNB.GM12878 351 bp overlap

ChIP GM12878 ENCSR000EYV.JUND.GM12878 144 bp overlap

KLF5 2 datasets

ChIP HEK293_D418N GSE88976.KLF5.HEK293_D418N 271 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 167 bp overlap

LIN54 1 dataset

Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap

ChIP HEK293 ENCFF994GSG 581 bp overlap

ChIP HEK293 ENCFF994GSG 337 bp overlap

MEF2B 1 dataset

ChIP tonsil GSE110682.MEF2B.tonsil 229 bp overlap

MEIS2 1 dataset

ChIP K-562 ENCSR851BNE.MEIS2.K-562 231 bp overlap

Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap

MTA2 3 datasets

ChIP GM12878 ENCFF615CWQ 571 bp overlap

ChIP GM12878 ENCFF615CWQ 470 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 326 bp overlap

ChIP CD4_TH2 GSE72266.MYB.CD4_TH2 296 bp overlap

ChIP CD4_Th1 GSE72266.MYB.CD4_Th1 148 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 141 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 206 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 136 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 241 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 337 bp overlap

ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 105 bp overlap

Motif DE_36h DE_36h-MYF6_MA0667.1 10 bp overlap

MYOD1 5 datasets

Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 255 bp overlap

ChIP SMS-CTR GSE137168.MYOD1.SMS-CTR 220 bp overlap

ChIP myoblast GSE50413.MYOD1.myoblast 206 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 207 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 298 bp overlap

NFIC 2 datasets

ChIP GM12878 ENCFF259FWL 559 bp overlap

ChIP GM12878 ENCSR000BRN.NFIC.GM12878 219 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 223 bp overlap

NR2F1 2 datasets

ChIP GM12878 ENCFF273VKX 505 bp overlap

ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 299 bp overlap

OSR2 2 datasets

ChIP HEK293 ENCFF875BDB 244 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 415 bp overlap

PATZ1 2 datasets

ChIP HEK293 ENCFF016MNJ 501 bp overlap

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 278 bp overlap

PAX5 8 datasets

ChIP GM12878 ENCFF482PUW 251 bp overlap

ChIP GM12878 ENCFF503GOV 305 bp overlap

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 253 bp overlap

ChIP GM12878 ENCSR000BHD.PAX5.GM12878 185 bp overlap

ChIP GM12891 ENCFF490KVF 205 bp overlap

ChIP GM12891 ENCSR000BJH.PAX5.GM12891 196 bp overlap

ChIP GM12892 ENCFF635MSF 277 bp overlap

ChIP GM12892 ENCSR000BJI.PAX5.GM12892 274 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 325 bp overlap

PPARA::RXRA 1 dataset

Motif DE_36h DE_36h-PPARARXRA_MA1148.2 17 bp overlap

PRDM1 1 dataset

Motif DE_36h DE_36h-PRDM1_MA0508.4 7 bp overlap

PRDM4 1 dataset

ChIP HEK293 ENCFF069PHD 385 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 279 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 371 bp overlap

PROX1 1 dataset

ChIP SW480 GSE60390.PROX1.SW480 184 bp overlap

Pparg::Rxra 1 dataset

Motif DE_36h DE_36h-PpargRxra_MA0065.3 13 bp overlap

Ptf1A 1 dataset

Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 291 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE76181.RUNX1.Jurkat 465 bp overlap

RUNX2 2 datasets

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 188 bp overlap

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 255 bp overlap

RUNX3 1 dataset

ChIP GM12878 ENCFF395WHA 209 bp overlap

SCRT1 3 datasets

Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap

ChIP HEK293 ENCFF513YVP 142 bp overlap

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 474 bp overlap

SCRT2 2 datasets

Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap

ChIP HEK293 ENCFF711QQB 507 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 392 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 155 bp overlap

ChIP GM12878 ENCSR212YKD.SKIL.GM12878 273 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 519 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 531 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 332 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 381 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 476 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 418 bp overlap

SMARCA4 2 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 324 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 240 bp overlap

ChIP DKO GSE131606.SMC1.DKO 197 bp overlap

ChIP HEK293T_CRISPR GSE122299.SMC3.HEK293T_CRISPR 294 bp overlap

SNAI2 2 datasets

Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 109 bp overlap

SOX11 1 dataset

ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 396 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 431 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 182 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 391 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 431 bp overlap

TAL1::TCF3 1 dataset

Motif DE_36h DE_36h-TAL1TCF3_MA0091.2 10 bp overlap

TBX21 2 datasets

ChIP GM12878 ENCFF951HUW 485 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 432 bp overlap

TCF7 2 datasets

ChIP GM12878 ENCFF749DPM 365 bp overlap

ChIP GM12878 ENCSR501DKS.TCF7.GM12878 233 bp overlap

TCF7L2 2 datasets

ChIP HEK293 ENCFF513JQN 505 bp overlap

ChIP HEK293 ENCSR000EUY.TCF7L2.HEK293 398 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 208 bp overlap

TFAP4 1 dataset

Motif DE_36h DE_36h-TFAP4_MA1570.1 10 bp overlap

Tcf21 1 dataset

Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 310 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 337 bp overlap

ZBTB7C 1 dataset

Motif DE_36h DE_36h-ZBTB7C_MA0695.2 8 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 558 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 400 bp overlap

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 247 bp overlap

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

ChIP HEK293 ENCFF033NQQ 444 bp overlap

Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap

Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap

ZNF143 1 dataset

Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap

ZNF18 2 datasets

ChIP HEK293 ENCFF066NGR 401 bp overlap

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 483 bp overlap

ZNF217 2 datasets

ChIP GM12878 ENCFF978IGL 465 bp overlap

ChIP GM12878 ENCSR764CZW.ZNF217.GM12878 276 bp overlap

ZNF263 1 dataset

ChIP HEK293 ENCFF336CWQ 371 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 154 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 181 bp overlap

ZNF558 1 dataset

Motif DE_36h DE_36h-ZNF558_MA2335.1 29 bp overlap

ZNF561 2 datasets

ChIP HEK293 ENCFF399XKF 441 bp overlap

ChIP HEK293 ENCSR125ULS.ZNF561.HEK293 213 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 341 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 230 bp overlap

ZNF843 2 datasets

ChIP HEK293 ENCFF241QRH 445 bp overlap

ChIP HEK293 ENCSR502KPJ.ZNF843.HEK293 265 bp overlap

ZSCAN5C 2 datasets

ChIP HEK293 ENCFF343DTU 106 bp overlap

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 541 bp overlap