chr7:100,270,225–100,270,813

chr7 : 100,270,225 – 100,270,813

588 bp 103 TFs 24 linked genes

This 588 bp open chromatin element is linked to 24 target genes and is bound by 103 transcription factors.

Linked Genes

24 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CASTOR3P		1.2 kb	Proximal	Proximity
ENSG00000291178		65.3 kb	Distal	Multiome+HiCAR
STAG3L5P		65.5 kb	Distal	Multiome+HiCAR
PILRB		86.7 kb	Distal	Multiome
STAG3		93.1 kb	Distal	Multiome
GPC2		93.2 kb	Distal	Multiome
GAL3ST4		102.0 kb	Distal	Multiome
PILRA		103.4 kb	Distal	Multiome
LAMTOR4		121.7 kb	Distal	Multiome
ENSG00000242798		143.5 kb	Distal	Multiome
CNPY4		151.0 kb	Distal	Multiome
TAF6		151.3 kb	Distal	Multiome
ZCWPW1		158.1 kb	Distal	Multiome
MEPCE		158.2 kb	Distal	Multiome
PPP1R35		165.8 kb	Distal	Multiome
MCM7		169.2 kb	Distal	Multiome
AP4M1		169.7 kb	Distal	Multiome
COPS6		181.7 kb	Distal	Multiome
ZNF3		188.9 kb	Distal	Multiome
TSC22D4		208.6 kb	Distal	Multiome
NYAP1		213.3 kb	Distal	Multiome
ZSCAN21		220.8 kb	Distal	Multiome
ZKSCAN1		255.0 kb	Distal	Multiome
AGFG2		268.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ARID3A 1 dataset

ChIP HepG2 ENCFF341DES 360 bp overlap

ARID4A 1 dataset

ChIP HepG2 ENCFF142DIE 462 bp overlap

ARID4B 1 dataset

ChIP HepG2 ENCFF519OXJ 217 bp overlap

ARID5B 1 dataset

ChIP HepG2 ENCFF964FWK 186 bp overlap

ChIP HepG2 ENCFF049UDY 403 bp overlap

CTCF 11 datasets

ChIP Caco-2 ENCFF753NZV 78 bp overlap

ChIP SK-N-SH ENCFF731NJX 201 bp overlap

ChIP body of pancreas ENCFF881RGF 211 bp overlap

ChIP chondrocyte ENCFF134ORZ 368 bp overlap

ChIP chondrocyte ENCFF134ORZ 143 bp overlap

ChIP choroid plexus epithelial cell ENCFF407YNR 173 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF245PVD 468 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF733NZH 54 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF733NZH 359 bp overlap

ChIP endodermal cell ENCFF471YCZ 264 bp overlap

ChIP progenitor cell of endocrine pancreas ENCFF492KHV 282 bp overlap

CTCFL 2 datasets

Motif DE_48h DE_48h-CTCFL_MA1102.3 8 bp overlap

Motif DE_72h DE_72h-CTCFL_MA1102.3 8 bp overlap

DNMT3B 1 dataset

ChIP HepG2 ENCFF341GEA 260 bp overlap

EBF3 2 datasets

Motif DE_48h DE_48h-EBF3_MA1637.2 9 bp overlap

Motif DE_72h DE_72h-EBF3_MA1637.2 9 bp overlap

EP300 3 datasets

ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 174 bp overlap

ChIP HepG2 ENCFF076TMZ 300 bp overlap

ChIP HepG2 ENCFF354ACD 280 bp overlap

ETV2::DRGX 1 dataset

Motif DE_48h DE_48h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::DRGX 1 dataset

Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap

Ebf2 2 datasets

Motif DE_48h DE_48h-Ebf2_MA1604.2 9 bp overlap

Motif DE_72h DE_72h-Ebf2_MA1604.2 9 bp overlap

FEZF2 1 dataset

Motif DE_48h DE_48h-FEZF2_MA2341.1 8 bp overlap

FOSL1 1 dataset

ChIP K562 ENCFF455MKD 239 bp overlap

FOSL2 3 datasets

ChIP A549 ENCFF195CES 64 bp overlap

ChIP Hep-G2 ENCSR000BHP.FOSL2.Hep-G2 89 bp overlap

ChIP SK-N-SH ENCFF127ZDW 153 bp overlap

FOXA1 5 datasets

ChIP HepG2 ENCFF207NVJ 281 bp overlap

ChIP HepG2 ENCFF361KNY 285 bp overlap

ChIP HepG2 ENCFF740VZW 285 bp overlap

ChIP LNCaP_ETOH24H GSE58428.FOXA1.LNCaP_ETOH24H 248 bp overlap

ChIP MCF-7_DOX-neg GSE124654.FOXA1.MCF-7_DOX-neg 220 bp overlap

FOXA2 6 datasets

ChIP DE DE-FOXA2-1 588 bp overlap

ChIP DE DE-FOXA2-2 588 bp overlap

ChIP HepG2 ENCFF533COJ 297 bp overlap

ChIP HepG2 ENCFF533COJ 280 bp overlap

ChIP HepG2 ENCFF570ABM 359 bp overlap

ChIP HepG2 ENCFF894AYY 115 bp overlap

FOXP4 1 dataset

ChIP HepG2 ENCFF462ULY 352 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 529 bp overlap

ChIP DE DE-GATA4-2 572 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 361 bp overlap

ChIP DE DE-GATA6-2 518 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 256 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 331 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 369 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 192 bp overlap

GATAD2A 1 dataset

ChIP HepG2 ENCFF252XNH 130 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 327 bp overlap

ChIP HEK293 ENCFF299RSE 457 bp overlap

GRHL2 1 dataset

Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap

ChIP HepG2 ENCFF927POV 346 bp overlap

HIVEP1 1 dataset

ChIP HepG2 ENCFF063BCC 78 bp overlap

HMGXB4 1 dataset

ChIP HepG2 ENCFF179TAD 336 bp overlap

HNF1A 3 datasets

ChIP HepG2 ENCFF352VYI 411 bp overlap

ChIP HepG2 ENCFF540TRC 389 bp overlap

ChIP HepG2 ENCFF540TRC 368 bp overlap

HNF4A 4 datasets

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 116 bp overlap

ChIP Hep-G2 ERP000209.HNF4A.Hep-G2 127 bp overlap

ChIP HepG2 ENCFF146SSF 243 bp overlap

ChIP HepG2 ENCFF669NAM 222 bp overlap

HNF4G 1 dataset

ChIP HepG2 ENCFF323ATZ 227 bp overlap

ChIP HepG2 ENCFF742RIP 346 bp overlap

ChIP A549 ENCFF846DUV 178 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 67 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 238 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 181 bp overlap

KDM1A 2 datasets

ChIP HepG2 ENCFF240UWG 464 bp overlap

ChIP HepG2 ENCFF240UWG 232 bp overlap

KDM2A 1 dataset

ChIP HepG2 ENCFF491GTR 53 bp overlap

ChIP HepG2 ENCFF499KCU 305 bp overlap

ChIP A549 ENCFF310XGQ 128 bp overlap

ChIP HepG2 ENCFF479OHI 331 bp overlap

ChIP HepG2 ENCFF507HCX 381 bp overlap

ChIP HepG2 ENCFF507HCX 429 bp overlap

ChIP HEK293 ENCFF994GSG 319 bp overlap

ChIP HepG2 ENCFF495TSS 352 bp overlap

ChIP HepG2 ENCFF938KYA 389 bp overlap

ChIP SK-N-SH ENCFF746HVJ 329 bp overlap

NCOA2 1 dataset

ChIP HepG2 ENCFF853BJJ 347 bp overlap

NCOR1 2 datasets

ChIP HepG2 ENCFF685NAH 492 bp overlap

ChIP HepG2 ENCFF685NAH 398 bp overlap

NFIA 2 datasets

Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap

Motif DE_72h DE_72h-NFIA_MA0670.2 6 bp overlap

ChIP SK-N-SH ENCFF965AKM 237 bp overlap

NFIX 2 datasets

Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap

Motif DE_72h DE_72h-NFIX_MA0671.2 6 bp overlap

NR2C2 1 dataset

ChIP HepG2 ENCFF944PRH 402 bp overlap

NR2F6 4 datasets

ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 124 bp overlap

ChIP HepG2 ENCFF429VKC 298 bp overlap

ChIP HepG2 ENCFF514UJI 163 bp overlap

ChIP K562 ENCFF674RQA 69 bp overlap

NR5A1 1 dataset

ChIP HepG2 ENCFF970YZO 238 bp overlap

NR5A2 2 datasets

ChIP A549 ENCFF834RVE 294 bp overlap

ChIP A549 ENCFF834RVE 94 bp overlap

ChIP HepG2 ENCFF694NVY 291 bp overlap

PATZ1 1 dataset

ChIP HepG2 ENCFF723PFC 159 bp overlap

PAXIP1 2 datasets

ChIP HepG2 ENCFF526NOJ 360 bp overlap

ChIP HepG2 ENCFF526NOJ 398 bp overlap

PHF21A 1 dataset

ChIP HepG2 ENCFF525EUW 457 bp overlap

PITX1 1 dataset

ChIP HepG2 ENCFF468QTQ 385 bp overlap

POU2F1 1 dataset

ChIP HepG2 ENCFF422JZU 360 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 351 bp overlap

PROX1 2 datasets

ChIP HepG2 ENCFF016ZJS 90 bp overlap

ChIP HepG2 ENCFF016ZJS 319 bp overlap

RAD21 1 dataset

ChIP HepG2 ENCFF906QIS 201 bp overlap

ChIP HepG2 ENCFF582XUA 262 bp overlap

RBFOX2 1 dataset

ChIP K562 ENCFF967GRF 476 bp overlap

RBM39 2 datasets

ChIP HepG2 ENCFF801JUH 428 bp overlap

ChIP HepG2 ENCFF801JUH 518 bp overlap

ChIP HepG2 ENCFF367CFI 379 bp overlap

RXRA 2 datasets

ChIP HepG2 ENCFF763IEA 388 bp overlap

ChIP HepG2 ENCFF763IEA 192 bp overlap

RXRB 2 datasets

Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap

Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap

Rxra 2 datasets

Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap

Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap

SAP130 2 datasets

ChIP HepG2 ENCFF892EHZ 355 bp overlap

ChIP HepG2 ENCFF892EHZ 263 bp overlap

SIN3A 5 datasets

ChIP A549 ENCFF752ATT 360 bp overlap

ChIP A549 ENCFF752ATT 117 bp overlap

ChIP H1 ENCFF042ZSL 321 bp overlap

ChIP HepG2 ENCFF394WQQ 329 bp overlap

ChIP MCF-7 ENCFF521RDC 113 bp overlap

ChIP HepG2 ENCFF631IPX 268 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 254 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 274 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 319 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 473 bp overlap

SMAD4 1 dataset

ChIP HepG2 ENCFF615GTE 118 bp overlap

SOX13 3 datasets

ChIP HepG2 ENCFF062VSQ 274 bp overlap

ChIP HepG2 ENCFF231PAK 341 bp overlap

ChIP HepG2 ENCFF231PAK 271 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 510 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 588 bp overlap

ChIP HepG2 ENCFF470KZD 275 bp overlap

SOX6 2 datasets

ChIP HepG2 ENCFF767OCK 202 bp overlap

ChIP HepG2 ENCFF767OCK 242 bp overlap

ChIP HepG2 ENCFF123KAM 265 bp overlap

TARDBP 2 datasets

ChIP HepG2 ENCFF356JNC 385 bp overlap

ChIP HepG2 ENCFF356JNC 422 bp overlap

TBX2 2 datasets

ChIP HepG2 ENCFF811TLA 427 bp overlap

ChIP HepG2 ENCFF811TLA 434 bp overlap

TCF7L2 1 dataset

ChIP HepG2 ENCFF510OLG 350 bp overlap

TGIF2 1 dataset

ChIP HepG2 ENCFF421ZJN 234 bp overlap

ChIP HepG2 ENCFF025KMX 219 bp overlap

YEATS2 1 dataset

ChIP HepG2 ENCFF409XOA 370 bp overlap

ZBTB20 1 dataset

ChIP HEK293 ENCFF524ADK 114 bp overlap

ZBTB34 1 dataset

ChIP HepG2 ENCFF161MIO 378 bp overlap

ZBTB40 3 datasets

ChIP GM12878 ENCFF346DYM 200 bp overlap

ChIP K562 ENCFF952IUD 124 bp overlap

ChIP MCF-7 ENCFF044DWL 146 bp overlap

ZBTB6 2 datasets

Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap

Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap

ZBTB7A 1 dataset

ChIP K562 ENCFF579ZGM 210 bp overlap

ZBTB7B 1 dataset

ChIP HepG2 ENCFF763OCV 150 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 156 bp overlap

ChIP HepG2 ENCFF016NZF 325 bp overlap

ChIP K562 ENCFF536AJO 373 bp overlap

ZNF275 2 datasets

ChIP HepG2 ENCFF015JKD 59 bp overlap

ChIP HepG2 ENCFF015JKD 258 bp overlap

ZNF276 1 dataset

ChIP HepG2 ENCFF431WQQ 397 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 63 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCFF944VMC 255 bp overlap

ZNF501 2 datasets

ChIP HepG2 ENCFF879XZR 544 bp overlap

ChIP HepG2 ENCFF879XZR 460 bp overlap

ZNF503 1 dataset

ChIP HepG2 ENCFF923HZL 357 bp overlap

ZNF528 1 dataset

Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap

ZNF549 1 dataset

Motif DE_72h DE_72h-ZNF549_MA1728.2 8 bp overlap

ZNF600 1 dataset

ChIP HEK293 ENCFF785JSX 231 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 267 bp overlap

ZSCAN31 1 dataset

Motif DE_48h DE_48h-ZSCAN31_MA1722.2 18 bp overlap

Zfp809 1 dataset

Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap