NR5A1

nuclear receptor subfamily 5 group A member 1 | AD4BP, ELP, FTZ1, SF-1, SF1, hSF-1, FTZF1

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008]

Biological processes 57 terms

DNA binding (GO:0003677)DNA binding (GO:0003677)DNA-binding transcription activator activity (GO:0001216)DNA-binding transcription factor activity (GO:0003700)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)RNA polymerase II transcription regulator complex (GO:0090575)RNA polymerase II transcription regulator complex (GO:0090575)RNA polymerase II transcription regulator complex (GO:0090575)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)calcineurin-mediated signaling (GO:0097720)chromatin (GO:0000785)chromatin binding (GO:0003682)chromatin binding (GO:0003682)enzyme binding (GO:0019899)female gonad development (GO:0008585)female gonad development (GO:0008585)hormone-mediated signaling pathway (GO:0009755)hormone-mediated signaling pathway (GO:0009755)intracellular receptor signaling pathway (GO:0030522)male gonad development (GO:0008584)male gonad development (GO:0008584)male sex determination (GO:0030238)negative regulation of female gonad development (GO:2000195)nuclear receptor activity (GO:0004879)nuclear receptor activity (GO:0004879)nucleoplasm (GO:0005654)nucleoplasm (GO:0005654)nucleoplasm (GO:0005654)nucleus (GO:0005634)nucleus (GO:0005634)phospholipid binding (GO:0005543)positive regulation of DNA-templated transcription (GO:0045893)positive regulation of gene expression (GO:0010628)positive regulation of gene expression (GO:0010628)positive regulation of male gonad development (GO:2000020)positive regulation of male gonad development (GO:2000020)positive regulation of transcription by RNA polymerase II (GO:0045944)positive regulation of transcription by RNA polymerase II (GO:0045944)positive regulation of transcription by RNA polymerase II (GO:0045944)primary sex determination (GO:0007538)protein binding (GO:0005515)regulation of DNA-templated transcription (GO:0006355)regulation of steroid biosynthetic process (GO:0050810)regulation of transcription by RNA polymerase II (GO:0006357)response to gonadotropin-releasing hormone (GO:0097210)sequence-specific DNA binding (GO:0043565)sequence-specific DNA binding (GO:0043565)sequence-specific double-stranded DNA binding (GO:1990837)sex determination (GO:0007530)tissue development (GO:0009888)transcription coregulator binding (GO:0001221)transcription coregulator binding (GO:0001221)zinc ion binding (GO:0008270)

Expression (TPM)