chr2:170,819,935–170,820,669

chr2 : 170,819,935 – 170,820,669

734 bp 95 TFs 5 linked genes

This 734 bp open chromatin element is linked to 5 target genes and is bound by 95 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000286611		625 bp	At TSS	Proximity
ENSG00000235934		2.0 kb	Proximal	Proximity
GAD1		3.8 kb	Proximal	Proximity
ERICH2		49.4 kb	Distal	Multiome
GORASP2		109.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ChIP NALM-6 GSE93626.AATF.NALM-6 341 bp overlap

ARID4B 3 datasets

ChIP PC-3 GSE116669.ARID4B.PC-3 432 bp overlap

ChIP WTC11 ENCFF441HDK 457 bp overlap

ChIP WTC11 ENCFF441HDK 281 bp overlap

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 621 bp overlap

ChIP WTC11 ENCFF885OBU 351 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 734 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 734 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 567 bp overlap

BMPR1A 1 dataset

ChIP HUVEC-C GSE60156.BMPR1A.HUVEC-C 167 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 734 bp overlap

BRD4 5 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 366 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 734 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 387 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 438 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 603 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 242 bp overlap

CBX7 2 datasets

ChIP lymphocyte_DMSO GSE110139.CBX7.lymphocyte_DMSO 175 bp overlap

ChIP lymphocyte_DMSO GSE110139.CBX7.lymphocyte_DMSO 225 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 171 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 129 bp overlap

CREB1 3 datasets

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 250 bp overlap

ChIP WTC11 ENCFF297VCI 371 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 576 bp overlap

CTCF 10 datasets

ChIP GM23338 ENCFF832KWE 605 bp overlap

ChIP H9 ENCFF152GTF 461 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 103 bp overlap

ChIP WA01 ENCSR000DLK.CTCF.WA01 98 bp overlap

ChIP endodermal cell ENCFF471YCZ 461 bp overlap

ChIP hESC_D2 GSE116862.CTCF.hESC_D2 175 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 731 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 526 bp overlap

ChIP neural progenitor cell ENCFF420RBO 411 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 194 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 610 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 110 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 734 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 199 bp overlap

ESRRA 2 datasets

ChIP WTC11 ENCFF591YCA 425 bp overlap

ChIP WTC11 ENCFF591YCA 389 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 249 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

EZH2 32 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 181 bp overlap

ChIP B-cell ENCSR000AUZ.EZH2.B-cell 434 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 126 bp overlap

ChIP GM23338 ENCFF613YON 210 bp overlap

ChIP GM23338 ENCFF613YON 288 bp overlap

ChIP H1 ENCFF232NZA 734 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 734 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 734 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 180 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 384 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 573 bp overlap

ChIP LNCaP GSE39459.EZH2.LNCaP 166 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 734 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 734 bp overlap

ChIP astrocyte ENCFF365JTP 454 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 734 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 498 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 656 bp overlap

ChIP fibroblast of lung ENCFF479BAW 605 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 223 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 459 bp overlap

ChIP hepatocyte ENCFF118DKH 357 bp overlap

ChIP hepatocyte ENCFF552DZB 545 bp overlap

ChIP hepatocyte ENCFF552DZB 372 bp overlap

ChIP keratinocyte ENCFF070STK 243 bp overlap

ChIP keratinocyte ENCFF070STK 449 bp overlap

ChIP myotube ENCSR000ASZ.EZH2.myotube 354 bp overlap

ChIP neural ENCSR511CUH.EZH2.neural 338 bp overlap

ChIP neural cell ENCFF610EPB 364 bp overlap

ChIP neural cell ENCFF610EPB 401 bp overlap

ChIP neural progenitor cell ENCFF018MKA 734 bp overlap

ChIP neural progenitor cell ENCFF472NFV 734 bp overlap

FOXA3 2 datasets

ChIP K562 ENCFF348SOM 339 bp overlap

ChIP K562 ENCFF348SOM 139 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXL2 2 datasets

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 322 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 379 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 525 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

GATA6 4 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 395 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 134 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 665 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 397 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 410 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 177 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 294 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 439 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 192 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 621 bp overlap

INO80 1 dataset

ChIP Huh-7 GSE97411.INO80.Huh-7 734 bp overlap

ChIP WTC11 ENCFF506LYD 377 bp overlap

IRF4 2 datasets

ChIP T-cell GSE136853.IRF4.T-cell 328 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 274 bp overlap

JARID2 4 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 734 bp overlap

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 310 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 226 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 458 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 327 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 82 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 266 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 386 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 482 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 194 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 657 bp overlap

ChIP H1 ENCFF601FOM 102 bp overlap

ChIP H1 ENCFF914VQY 367 bp overlap

ChIP SK-N-SH ENCFF285LXR 411 bp overlap

ChIP SK-N-SH ENCSR000BVD.MAX.SK-N-SH 187 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 363 bp overlap

ChIP WTC11 ENCFF223QFY 585 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EEZ.MAX.endothelial_umbilical-vein 154 bp overlap

ChIP liver ENCFF092GVW 481 bp overlap

ChIP liver ENCSR847DIT.MAX.liver 203 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 528 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 167 bp overlap

MXI1 3 datasets

ChIP H1 ENCFF963FZS 337 bp overlap

ChIP WA01 ENCSR000EBR.MXI1.WA01 229 bp overlap

ChIP neural cell ENCFF623HQN 71 bp overlap

ChIP BJ_INDUCED GSE36570.MYC.BJ_INDUCED 219 bp overlap

ChIP H1 ENCFF794ZJT 265 bp overlap

MYCN 3 datasets

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 635 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 301 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 231 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 333 bp overlap

NANOG 1 dataset

ChIP WA01 ENCSR000BMT.NANOG.WA01 193 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 377 bp overlap

NR2C2 2 datasets

ChIP WTC11 ENCFF896ODS 371 bp overlap

ChIP WTC11 ENCFF896ODS 337 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 341 bp overlap

PCGF2 3 datasets

ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 225 bp overlap

ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 216 bp overlap

ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 197 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 296 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 208 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 681 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 193 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 690 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 346 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 603 bp overlap

RBFOX2 3 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 531 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 531 bp overlap

ChIP K562 ENCFF196WTG 728 bp overlap

RBM22 1 dataset

ChIP K-562 GSE120104.RBM22.K-562 188 bp overlap

RNF2 8 datasets

ChIP GM12878 ENCSR679FAB.RNF2.GM12878 208 bp overlap

ChIP H1 ENCFF239FFS 278 bp overlap

ChIP H1 ENCFF239FFS 686 bp overlap

ChIP H1 ENCFF239FFS 486 bp overlap

ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 707 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 494 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 252 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 170 bp overlap

RUVBL2 1 dataset

ChIP Huh-7 GSE97411.RUVBL2.Huh-7 280 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 482 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000BIS.SIN3A.WA01 218 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 216 bp overlap

ChIP WTC11 ENCFF891HYW 377 bp overlap

SMAD2-3 5 datasets

ChIP HGrC1_C134W-TGF GSE138496.SMAD2-3.HGrC1_C134W-TGF 221 bp overlap

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 469 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 526 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 470 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 680 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 322 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 618 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 338 bp overlap

SMAD3 1 dataset

ChIP WTC11 ENCFF815YYQ 357 bp overlap

SMAD4 2 datasets

ChIP HGrC1_C134W-TGF GSE138496.SMAD4.HGrC1_C134W-TGF 242 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.SMAD4.HGrC1_C134W-TGF_parental 411 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 179 bp overlap

SMARCC1 4 datasets

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 734 bp overlap

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 560 bp overlap

ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 624 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 262 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 271 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 178 bp overlap

ChIP H1 ENCFF263FUH 139 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP SYO-1 GSE108025.SS18.SYO-1 641 bp overlap

SUZ12 8 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 734 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 385 bp overlap

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 298 bp overlap

ChIP H1 ENCFF881NFR 734 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 197 bp overlap

ChIP NCCIT GSE71675.SUZ12.NCCIT 665 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 212 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 357 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 143 bp overlap

TAF15 1 dataset

ChIP K-562 ENCSR047LSJ.TAF15.K-562 222 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 237 bp overlap

TCF7L2 1 dataset

ChIP CD34_PROG_BIO GSE29194.TCF7L2.CD34_PROG_BIO 172 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 305 bp overlap

ChIP Jurkat_NCKD GSE85524.TET2.Jurkat_NCKD 262 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 430 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 234 bp overlap

TGIF2 1 dataset

ChIP WTC11 ENCFF649SHI 441 bp overlap

ChIP WTC11 ENCFF359JCU 537 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 626 bp overlap

USF1 4 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 217 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 315 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

USF2 3 datasets

ChIP H1 ENCFF434EDF 277 bp overlap

ChIP WA01 ENCSR000ECD.USF2.WA01 204 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 196 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 641 bp overlap

ChIP K562 ENCFF875HLX 118 bp overlap

ChIP WTC11 ENCFF048CFR 391 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 485 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 276 bp overlap

ZBTB7A 1 dataset

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 198 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 461 bp overlap

ZNF263 1 dataset

ChIP WTC11 ENCFF893RTM 437 bp overlap

ZNF281 2 datasets

ChIP WTC11 ENCFF551GAV 377 bp overlap

ChIP WTC11 ENCFF551GAV 323 bp overlap