chr2:72,951,372–72,951,860

chr2 : 72,951,372 – 72,951,860

488 bp 115 TFs 6 linked genes

This 488 bp open chromatin element is linked to 6 target genes and is bound by 115 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SFXN5		120.2 kb	Distal	Multiome
EXOC6B		125.5 kb	Distal	Multiome
RAB11FIP5		161.5 kb	Distal	Multiome
SMYD5		262.7 kb	Distal	Multiome
PRADC1		281.7 kb	Distal	Multiome
CCT7		282.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

115 transcription factors

ChIP HepG2 ENCFF773YDL 190 bp overlap

ASCL1 2 datasets

Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap

Motif ES_0h ES_0h-ASCL1_MA1631.2 9 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 305 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 291 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 334 bp overlap

Ascl2 2 datasets

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 283 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 285 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 208 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 488 bp overlap

BRD4 3 datasets

ChIP Mutu-1_vehicle GSE84213.BRD4.Mutu-1_vehicle 156 bp overlap

ChIP hESC GSE33281.BRD4.hESC 100 bp overlap

ChIP hESC GSE33281.BRD4.hESC 110 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 179 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 193 bp overlap

CREB1 4 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 456 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 161 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 117 bp overlap

CTBP2 3 datasets

ChIP H1 ENCFF329MAX 426 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 297 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 109 bp overlap

ChIP GM23338 ENCFF772DML 135 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 161 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 382 bp overlap

EGR1 2 datasets

ChIP H1 ENCFF451BLH 261 bp overlap

ChIP WA01 ENCSR000BJA.EGR1.WA01 129 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 327 bp overlap

ChIP WA01 ENCSR000AUQ.EP300.WA01 223 bp overlap

ChIP MDA-MB-231_LQ_45min GSE95121.ESR1.MDA-MB-231_LQ_45min 100 bp overlap

ETS1 4 datasets

ChIP GM23338 ENCFF701IZH 200 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 305 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 125 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 386 bp overlap

ETV1 2 datasets

ChIP GIST-T1 GSE106624.ETV1.GIST-T1 185 bp overlap

ChIP GIST-T1 GSE80443.ETV1.GIST-T1 129 bp overlap

ETV2::FIGLA 2 datasets

Motif DE_12h DE_12h-ETV2FIGLA_MA1941.2 13 bp overlap

Motif ES_0h ES_0h-ETV2FIGLA_MA1941.2 13 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 350 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

FIGLA 2 datasets

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap

FOXF1 1 dataset

ChIP GIST-T1 GSE106624.FOXF1.GIST-T1 180 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 488 bp overlap

HDAC2 5 datasets

ChIP H1 ENCFF353UJQ 351 bp overlap

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 361 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 140 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 89 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 144 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 254 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 488 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 488 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 488 bp overlap

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

KLF17 1 dataset

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

ChIP WTC11 ENCFF223QFY 455 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 218 bp overlap

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

Motif ES_0h ES_0h-MSC_MA0665.1 10 bp overlap

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 110 bp overlap

ChIP DU528 GSE94000.MYB.DU528 226 bp overlap

ChIP PF-382 GSE94000.MYB.PF-382 241 bp overlap

ChIP Ramos GSE30726.MYC.Ramos 287 bp overlap

NANOG 9 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 214 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 488 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 379 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 276 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 255 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 477 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 423 bp overlap

NIPBL 5 datasets

ChIP WA09 GSE105028.NIPBL.WA09 369 bp overlap

ChIP hESC GSE64758.NIPBL.hESC 347 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 295 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 375 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 282 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 383 bp overlap

NR1D1 2 datasets

Motif DE_12h DE_12h-NR1D1_MA1531.2 14 bp overlap

Motif ES_0h ES_0h-NR1D1_MA1531.2 14 bp overlap

NR1D2 2 datasets

Motif DE_12h DE_12h-NR1D2_MA1532.2 15 bp overlap

Motif ES_0h ES_0h-NR1D2_MA1532.2 15 bp overlap

NR5A1 2 datasets

Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap

Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 335 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 213 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 278 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 267 bp overlap

PLAG1 1 dataset

Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 433 bp overlap

ChIP H1 ENCFF566JSR 456 bp overlap

ChIP H1 ENCFF833NJP 351 bp overlap

POU5F1 8 datasets

ChIP BG03 GSE21614.POU5F1.BG03 170 bp overlap

ChIP BG03 GSE21614.POU5F1.BG03 110 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 449 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 279 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 334 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 234 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 202 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 488 bp overlap

Plagl1 1 dataset

Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap

RAD21 3 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 231 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 157 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 61 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 488 bp overlap

RBM22 1 dataset

ChIP K-562 GSE120104.RBM22.K-562 61 bp overlap

RNF2 2 datasets

ChIP WA09 GSE105028.RNF2.WA09 437 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 488 bp overlap

RREB1 1 dataset

Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap

Rarb 2 datasets

Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap

Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap

Rarg 2 datasets

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 174 bp overlap

SMAD2 3 datasets

ChIP hESC GSE29422.SMAD2.hESC 158 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 311 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 322 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 355 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 316 bp overlap

SMAD2_3 2 datasets

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 321 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 357 bp overlap

SMAD3 5 datasets

ChIP BG03 GSE21614.SMAD3.BG03 426 bp overlap

ChIP BG03 GSE36578.SMAD3.BG03 81 bp overlap

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 276 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 277 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 354 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 199 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 337 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 208 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 488 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 383 bp overlap

SNAI1 2 datasets

Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap

Motif ES_0h ES_0h-SNAI1_MA1558.2 7 bp overlap

SOX12 1 dataset

Motif DE_12h DE_12h-SOX12_MA1561.2 10 bp overlap

SOX2 2 datasets

ChIP hESC GSE69479.SOX2.hESC 187 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 408 bp overlap

ChIP H1 ENCFF263FUH 83 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 344 bp overlap

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

TAF1 2 datasets

ChIP WA01 ENCSR000BHO.TAF1.WA01 134 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 141 bp overlap

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 175 bp overlap

ChIP hESC GSE122298.TBP.hESC 228 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 154 bp overlap

TCF12 4 datasets

Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap

Motif ES_0h ES_0h-TCF12_MA1648.2 7 bp overlap

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 475 bp overlap

TCF3 3 datasets

Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap

Motif ES_0h ES_0h-TCF3_MA0522.4 7 bp overlap

ChIP NPC GSE154479.TCF3.NPC 488 bp overlap

TCF4 2 datasets

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

Motif ES_0h ES_0h-TCF4_MA0830.3 8 bp overlap

TCF7L1 2 datasets

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap

TEAD1 3 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 291 bp overlap

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 150 bp overlap

TEAD3 1 dataset

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

TEAD4 4 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 385 bp overlap

ChIP H1 ENCFF778PAX 155 bp overlap

ChIP WTC11 ENCFF114TZS 335 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 277 bp overlap

TFAP2C 3 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 120 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 147 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 126 bp overlap

ChIP WTC11 ENCFF359JCU 238 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 187 bp overlap

VEZF1 1 dataset

Motif DE_12h DE_12h-VEZF1_MA1578.2 6 bp overlap

ChIP WA01 GSE99202.YAP1.WA01 316 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 256 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 112 bp overlap

ZEB1 2 datasets

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 173 bp overlap

ChIP HepG2 ENCFF016NZF 144 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 190 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 145 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 465 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 202 bp overlap

ZNF281 2 datasets

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ChIP WTC11 ENCFF551GAV 377 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 80 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 488 bp overlap

ZNF532 1 dataset

ChIP WTC11 ENCFF373VBX 181 bp overlap

ZNF652 2 datasets

ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 163 bp overlap

ChIP HepG2 ENCFF331VPZ 244 bp overlap

ZNF684 1 dataset

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

ZNF740 1 dataset

Motif DE_12h DE_12h-ZNF740_MA0753.3 10 bp overlap