chr7:23,116,020–23,116,472

chr7 : 23,116,020 – 23,116,472

452 bp 105 TFs 6 linked genes

This 452 bp open chromatin element is linked to 6 target genes and is bound by 105 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
KLHL7		10.4 kb	Distal	Multiome
NUP42		65.9 kb	Distal	Multiome
HYCC1		102.0 kb	Distal	Multiome
MALSU1		183.2 kb	Distal	Multiome
SNHG26		261.9 kb	Distal	Multiome
TOMM7		293.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

ChIP LNCaP_M253K_shFOXA1_Ethanol GSE128883.AR.LNCaP_M253K_shFOXA1_Ethanol 248 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 452 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 428 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 423 bp overlap

BCL11A 3 datasets

ChIP H1 ENCFF836SSR 177 bp overlap

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 212 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 135 bp overlap

BCOR 3 datasets

ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 137 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 225 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 346 bp overlap

ChIP HUVEC-C GSE60171.BRD3.HUVEC-C 206 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 255 bp overlap

CHD2 2 datasets

ChIP H1 ENCFF991MKH 303 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 194 bp overlap

CHD7 4 datasets

ChIP H1 ENCFF126NLU 233 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 452 bp overlap

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 383 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 452 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 218 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 378 bp overlap

CTCF 2 datasets

ChIP chondrocyte ENCFF134ORZ 150 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 55 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 165 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 288 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 226 bp overlap

ChIP hESC GSE17917.EP300.hESC 271 bp overlap

Motif ES_0h ES_0h-ETV1_MA0761.3 9 bp overlap

ETV2::FOXI1 1 dataset

Motif ES_0h ES_0h-ETV2FOXI1_MA1942.2 11 bp overlap

ChIP WTC11 ENCFF812SCD 398 bp overlap

EZH2 2 datasets

ChIP WSU-DLCL2 GSE45982.EZH2.WSU-DLCL2 121 bp overlap

ChIP neural progenitor cell ENCFF018MKA 452 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 271 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 208 bp overlap

FLI1::FOXI1 1 dataset

Motif ES_0h ES_0h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 309 bp overlap

FOXO1::ELF1 1 dataset

Motif ES_0h ES_0h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif ES_0h ES_0h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif ES_0h ES_0h-FOXO1FLI1_MA1956.2 13 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 257 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 280 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 174 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 325 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 201 bp overlap

HOXA3 1 dataset

Motif ES_0h ES_0h-HOXA3_MA2119.1 7 bp overlap

HOXA4 1 dataset

Motif ES_0h ES_0h-HOXA4_MA1496.2 7 bp overlap

HOXA5 1 dataset

Motif ES_0h ES_0h-HOXA5_MA0158.2 8 bp overlap

HOXB4 1 dataset

Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap

HOXD3 1 dataset

Motif ES_0h ES_0h-HOXD3_MA0912.2 8 bp overlap

HOXD4 1 dataset

Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap

Motif ES_0h ES_0h-HSF1_MA0486.2 13 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif ES_0h ES_0h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_12h DE_12h-Isl1_MA1608.2 7 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 279 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 251 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 359 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 199 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 395 bp overlap

ChIP WA01 ENCSR000EBZ.JUND.WA01 211 bp overlap

ChIP hESC GSE64758.LEF1.hESC 253 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 440 bp overlap

ChIP WTC11 ENCFF223QFY 232 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 293 bp overlap

MEIS1 3 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MEIS2 2 datasets

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

Motif ES_0h ES_0h-MEIS2_MA0774.1 8 bp overlap

MEIS3 2 datasets

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

Motif ES_0h ES_0h-MEIS3_MA0775.2 7 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 430 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 191 bp overlap

ChIP WA01 ENCSR000EBR.MXI1.WA01 152 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 452 bp overlap

MYOD1 1 dataset

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 305 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 287 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 241 bp overlap

ChIP H1 ENCFF747ZPQ 95 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 452 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 437 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 311 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 452 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 403 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 434 bp overlap

ChIP hESC GSE18292.NANOG.hESC 180 bp overlap

ChIP hESC GSE20650.NANOG.hESC 304 bp overlap

NIPBL 4 datasets

ChIP hESC GSE64758.NIPBL.hESC 240 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 211 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 263 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 227 bp overlap

NKX6-3 1 dataset

Motif DE_12h DE_12h-NKX6-3_MA1530.2 8 bp overlap

NR5A1 1 dataset

Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

PAX3-FOXO1 1 dataset

ChIP Hs-352-Sk_PAX3-FOXO1-vector GSE83725.PAX3-FOXO1.Hs-352-Sk_PAX3-FOXO1-vector 234 bp overlap

Motif ES_0h ES_0h-PBX1_MA0070.2 9 bp overlap

Motif ES_0h ES_0h-PGR_MA2327.1 9 bp overlap

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 227 bp overlap

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 228 bp overlap

ChIP T-47D_R5020-MTVL GSE126859.PGR.T-47D_R5020-MTVL 235 bp overlap

POU2F1 1 dataset

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 261 bp overlap

POU5F1 7 datasets

Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 407 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 395 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 201 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 452 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 336 bp overlap

POU5F1B 1 dataset

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

RAD21 1 dataset

ChIP K-562_RF2-insertion GSE140868.RAD21.K-562_RF2-insertion 74 bp overlap

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 290 bp overlap

Motif ES_0h ES_0h-RARG_MA1553.2 13 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 92 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 148 bp overlap

RELA 3 datasets

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

Motif ES_0h ES_0h-RELA_MA0107.1 10 bp overlap

ChIP KB_IL GSE52469.RELA.KB_IL 220 bp overlap

REST 2 datasets

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 156 bp overlap

SAP30 2 datasets

ChIP H1 ENCFF149IOE 442 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 363 bp overlap

SIN3A 5 datasets

ChIP H1 ENCFF042ZSL 432 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 434 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 348 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 147 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 183 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 275 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-siAP GSE122631.SMARCA2.NPC_K755R-siAP 234 bp overlap

ChIP NPC_R1159Q_AM GSE122631.SMARCA2.NPC_R1159Q_AM 297 bp overlap

SMARCA4 8 datasets

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 217 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 205 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 359 bp overlap

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 404 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 452 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 342 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 382 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 413 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 362 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 440 bp overlap

SMARCC1 4 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 326 bp overlap

ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 237 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 390 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 317 bp overlap

SOX10 1 dataset

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX12 1 dataset

Motif ES_0h ES_0h-SOX12_MA1561.2 10 bp overlap

SOX14 1 dataset

Motif ES_0h ES_0h-SOX14_MA1562.2 9 bp overlap

SOX2 10 datasets

ChIP H9 GSE46837.SOX2.H9 269 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 452 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 255 bp overlap

ChIP hESC GSE69479.SOX2.hESC 290 bp overlap

ChIP hESC GSE18292.SOX2.hESC 114 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 360 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 395 bp overlap

ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 269 bp overlap

ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 307 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 295 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 351 bp overlap

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap

ChIP H1 ENCFF263FUH 270 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 355 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 295 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 208 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 276 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 248 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 214 bp overlap

ChIP NPC GSE154479.TCF3.NPC 340 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 352 bp overlap

TEAD3 1 dataset

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 431 bp overlap

ChIP H1 ENCFF778PAX 162 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 246 bp overlap

ChIP WTC11 ENCFF699QGS 186 bp overlap

ChIP WA01 GSE99202.YAP1.WA01 291 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 367 bp overlap

ZNF143 2 datasets

ChIP WA09 GSE105028.ZNF143.WA09 310 bp overlap

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 297 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 327 bp overlap

ZNF214 2 datasets

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

Motif ES_0h ES_0h-ZNF214_MA1975.2 13 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 302 bp overlap

ZNF600 1 dataset

ChIP HEK293 ENCFF785JSX 244 bp overlap

Zic2 2 datasets

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap