chr22:32,175,754–32,176,273

chr22 : 32,175,754 – 32,176,273

519 bp 106 TFs 6 linked genes

This 519 bp open chromatin element is linked to 6 target genes and is bound by 106 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RFPL2		29.0 kb	Distal	Multiome
SLC5A4-AS1		29.1 kb	Distal	Multiome
ENSG00000273325		108.6 kb	Distal	Multiome
YWHAH		231.5 kb	Distal	Multiome
RTCB		236.2 kb	Distal	Multiome
FBXO7		298.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

106 transcription factors

ChIP LNCaP GSE80256.AR.LNCaP 103 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 254 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 194 bp overlap

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 273 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 254 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 519 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 414 bp overlap

BAF155 1 dataset

ChIP VCaP_shERG GSE110655.BAF155.VCaP_shERG 260 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 260 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 519 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 519 bp overlap

BRD4 10 datasets

ChIP LNCaP-clone-FGC_DHT-Enzalutamide GSE118247.BRD4.LNCaP-clone-FGC_DHT-Enzalutamide 224 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 198 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 246 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 149 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 166 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 519 bp overlap

ChIP VCaP_Darolutamide GSE148358.BRD4.VCaP_Darolutamide 100 bp overlap

ChIP VCaP_R1881 GSE148358.BRD4.VCaP_R1881 487 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 378 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 311 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 366 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 216 bp overlap

CREB1 2 datasets

ChIP WA01 ENCSR000BSN.CREB1.WA01 79 bp overlap

ChIP WTC11 ENCFF297VCI 296 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 322 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 195 bp overlap

CTCF 16 datasets

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 56 bp overlap

ChIP CD14-positive monocyte ENCFF087XLR 101 bp overlap

ChIP GM23338 ENCFF772DML 183 bp overlap

ChIP GM23338 ENCFF832KWE 173 bp overlap

ChIP H1 ENCFF764RHO 180 bp overlap

ChIP H1 ENCFF764RHO 277 bp overlap

ChIP HEK293 ENCFF498RMM 109 bp overlap

ChIP NB69 GSE101295.CTCF.NB69 132 bp overlap

ChIP VCaP ENCFF858YQT 285 bp overlap

ChIP hiPSC_CVI GSE106870.CTCF.hiPSC_CVI 132 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 133 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 81 bp overlap

ChIP neural progenitor cell ENCFF581WPG 136 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 75 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 172 bp overlap

ChIP retina_AB1-FW14 GSE86981.CTCF.retina_AB1-FW14 148 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 95 bp overlap

ChIP WTC11 ENCFF994SXO 311 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 198 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 151 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 237 bp overlap

ChIP ProEs GSE59087.EED.ProEs 109 bp overlap

EP300 2 datasets

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 254 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 228 bp overlap

EPAS1 1 dataset

ChIP 501-mel GSE95280.EPAS1.501-mel 351 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 238 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 352 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 200 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 185 bp overlap

ESR1 2 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 334 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 96 bp overlap

EZH2 19 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 264 bp overlap

ChIP A-673 ENCSR179SAO.EZH2.A-673 519 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 464 bp overlap

ChIP H1 ENCFF232NZA 388 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 519 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 519 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 519 bp overlap

ChIP astrocyte ENCFF365JTP 472 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 519 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 519 bp overlap

ChIP keratinocyte ENCFF070STK 519 bp overlap

ChIP keratinocyte ENCFF070STK 378 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 519 bp overlap

ChIP neural progenitor cell ENCFF472NFV 350 bp overlap

ChIP neural progenitor cell ENCFF472NFV 242 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 404 bp overlap

ChIP prostate-cancer_HA GSE107780.EZH2.prostate-cancer_HA 220 bp overlap

ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 519 bp overlap

ChIP prostate-cancer_shEZH2 GSE107780.EZH2.prostate-cancer_shEZH2 222 bp overlap

EZH2_phosphoT487 2 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 203 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 519 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 72 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 235 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 238 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 367 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 186 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 519 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 127 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 208 bp overlap

HIF1A 1 dataset

ChIP 501-mel GSE95280.HIF1A.501-mel 222 bp overlap

HMGXB4 2 datasets

ChIP WTC11 ENCFF962POR 496 bp overlap

ChIP WTC11 ENCFF962POR 165 bp overlap

ChIP WTC11 ENCFF506LYD 297 bp overlap

ChIP WTC11 ENCFF591FTP 420 bp overlap

JARID2 4 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 327 bp overlap

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 519 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 519 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 266 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 351 bp overlap

ChIP WTC11 ENCFF172UDA 253 bp overlap

KDM4A 5 datasets

ChIP H1 ENCFF078LED 166 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 519 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 445 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 242 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 84 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 256 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 95 bp overlap

ChIP H1 ENCFF914VQY 182 bp overlap

ChIP H1 ENCFF914VQY 183 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 519 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 519 bp overlap

ChIP WTC11 ENCFF223QFY 463 bp overlap

ChIP WTC11 ENCFF223QFY 402 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 182 bp overlap

MECOM 1 dataset

ChIP SKH1_CEBPA-ER GSE102697.MECOM.SKH1_CEBPA-ER 209 bp overlap

MED1 2 datasets

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 110 bp overlap

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 356 bp overlap

MYBL2 2 datasets

ChIP WTC11 ENCFF166TKT 446 bp overlap

ChIP WTC11 ENCFF166TKT 242 bp overlap

ChIP NB69 GSE138295.MYC.NB69 156 bp overlap

ChIP NCI-H128 GSE41105.MYC.NCI-H128 82 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 519 bp overlap

MYCN 2 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 241 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 519 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 519 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 184 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 462 bp overlap

NFE2L1 3 datasets

ChIP WTC11 ENCFF644BPU 180 bp overlap

ChIP WTC11 ENCFF644BPU 377 bp overlap

ChIP WTC11 ENCFF644BPU 223 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 178 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 338 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 519 bp overlap

ChIP HMEC-1 GSE67867.NRF1.HMEC-1 108 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 207 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 201 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 150 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 508 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 519 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 119 bp overlap

ChIP BG03 GSE21614.POU5F1.BG03 280 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 519 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 320 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 197 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 508 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 515 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 223 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 212 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 519 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 479 bp overlap

RUNX1 1 dataset

ChIP AML GSE111821.RUNX1.AML 312 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 319 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 519 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 204 bp overlap

SIN3A 3 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 157 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 137 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 299 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 325 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 519 bp overlap

SMAD2_3 1 dataset

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 456 bp overlap

SMARCA4 3 datasets

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 313 bp overlap

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 482 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 331 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 519 bp overlap

ChIP monocyte_IFNg-LPS GSE120943.SMC1.monocyte_IFNg-LPS 158 bp overlap

SMC1A 1 dataset

ChIP monocyte_INFg GSE98367.SMC1A.monocyte_INFg 119 bp overlap

ChIP neural ENCSR404BPV.SMC3.neural 316 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 164 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 219 bp overlap

ChIP WTC11 ENCFF688PEU 454 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 519 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 475 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 519 bp overlap

SUZ12 9 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 438 bp overlap

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 519 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 519 bp overlap

ChIP H1 ENCFF881NFR 519 bp overlap

ChIP LNCaP GSE39459.SUZ12.LNCaP 384 bp overlap

ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 519 bp overlap

ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 462 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 519 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 519 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 50 bp overlap

TCF12 2 datasets

ChIP WA01 ENCSR000BIT.TCF12.WA01 120 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 124 bp overlap

TCF3 2 datasets

ChIP NPC GSE154479.TCF3.NPC 160 bp overlap

ChIP NPC GSE154479.TCF3.NPC 173 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 296 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 415 bp overlap

ChIP WTC11 ENCFF114TZS 242 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 519 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 496 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 439 bp overlap

TGIF2 1 dataset

ChIP WTC11 ENCFF649SHI 409 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 113 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 342 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 79 bp overlap

ChIP WTC11 ENCFF699QGS 253 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 474 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 119 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 161 bp overlap

ZBTB1 2 datasets

ChIP Jurkat_ZBTB1-KO_Asp-deprivation_cDNA GSE145783.ZBTB1.Jurkat_ZBTB1-KO_Asp-deprivation_cDNA 231 bp overlap

ChIP Jurkat_ZBTB1-KO_cDNA GSE145783.ZBTB1.Jurkat_ZBTB1-KO_cDNA 223 bp overlap

ZBTB26 2 datasets

ChIP HEK293 ENCFF752POA 519 bp overlap

ChIP HEK293 ENCFF752TCU 519 bp overlap

ZBTB33 1 dataset

ChIP WTC11 ENCFF048CFR 185 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 439 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 519 bp overlap

ZBTB7A 2 datasets

ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 296 bp overlap

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 121 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 183 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 519 bp overlap

ZNF10 1 dataset

ChIP HEK293T GSE78099.ZNF10.HEK293T 125 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 205 bp overlap

ZNF281 1 dataset

ChIP WTC11 ENCFF551GAV 219 bp overlap

ZNF560 1 dataset

ChIP HEK293 ENCFF901CEW 205 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 117 bp overlap