chr6 : 50,707,719 – 50,708,228
509 bp 122 TFs 1 linked gene
This 509 bp open chromatin element is linked to TFAP2D and is bound by 122 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TFAP2D 9.8 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:50,702,719 – 50,713,228
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
122 transcription factors
Source
Cell type
AR 6 datasets
ChIP 22Rv1_siARFL_R1881 GSE80742.AR.22Rv1_siARFL_R1881 399 bp overlap
ChIP LNCaP-95_NT GSE125552.AR.LNCaP-95_NT 232 bp overlap
ChIP LNCaP_FOXA1 ERP003503.AR.LNCaP_FOXA1 176 bp overlap
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 201 bp overlap
ChIP prostate-cancer_PDX_35 GSE130408.AR.prostate-cancer_PDX_35 301 bp overlap
ChIP prostate-cancer_PDX_58 GSE130408.AR.prostate-cancer_PDX_58 186 bp overlap
ASCL1 1 dataset
Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap
Ascl2 1 dataset
Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 423 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 328 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 447 bp overlap
BHLHE22 1 dataset
Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap
BMI1 1 dataset
ChIP LNCaP-C4-2 GSE97831.BMI1.LNCaP-C4-2 225 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 473 bp overlap
BRD2 2 datasets
ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 161 bp overlap
ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 100 bp overlap
Bhlha15 1 dataset
Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap
CBFB 1 dataset
ChIP ME-1 GSE46044.CBFB.ME-1 349 bp overlap
CBX8 1 dataset
ChIP H1 ENCFF095JHA 152 bp overlap
CHD1 3 datasets
ChIP H1 ENCFF998XEK 409 bp overlap
ChIP WA01 ENCSR000AQK.CHD1.WA01 394 bp overlap
ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 260 bp overlap
CTBP2 3 datasets
ChIP H1 ENCFF329MAX 436 bp overlap
ChIP H1 ENCFF329MAX 464 bp overlap
ChIP WA01 ENCSR000EUO.CTBP2.WA01 371 bp overlap
CTCF 2 datasets
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
ChIP erythroid GSE67783.CTCF.erythroid 255 bp overlap
CTCFL 1 dataset
Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 222 bp overlap
E2F1 1 dataset
ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 165 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 122 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 295 bp overlap
EBF1 1 dataset
ChIP ASC GSE54889.EBF1.ASC 152 bp overlap
EED 1 dataset
ChIP ProEs GSE59087.EED.ProEs 131 bp overlap
ESR1 8 datasets
ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 340 bp overlap
ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 288 bp overlap
ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 250 bp overlap
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 328 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 177 bp overlap
ChIP breast_tumor_Female_6 GSE104399.ESR1.breast_tumor_Female_6 198 bp overlap
ChIP breast_tumor_Male_4 GSE104399.ESR1.breast_tumor_Male_4 189 bp overlap
ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 292 bp overlap
EZH2 31 datasets
ChIP A673 ENCFF955JRZ 336 bp overlap
ChIP GM23338 ENCFF613YON 173 bp overlap
ChIP GM23338 ENCFF613YON 296 bp overlap
ChIP H1 ENCFF232NZA 509 bp overlap
ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 287 bp overlap
ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 315 bp overlap
ChIP LNCaP GSE39459.EZH2.LNCaP 221 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 449 bp overlap
ChIP SF8628 GSE94834.EZH2.SF8628 278 bp overlap
ChIP SF8628 GSE94834.EZH2.SF8628 124 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 316 bp overlap
ChIP VCaP_ETOH GSE28950.EZH2.VCaP_ETOH 215 bp overlap
ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 321 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 130 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 509 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 509 bp overlap
ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 344 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 460 bp overlap
ChIP hESC GSE113817.EZH2.hESC 400 bp overlap
ChIP hepatocyte ENCFF552DZB 509 bp overlap
ChIP hepatocyte ENCFF552DZB 438 bp overlap
ChIP keratinocyte ENCFF070STK 315 bp overlap
ChIP keratinocyte ENCFF070STK 509 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 462 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 337 bp overlap
ChIP myotube ENCSR000ASZ.EZH2.myotube 63 bp overlap
ChIP neural ENCSR511CUH.EZH2.neural 217 bp overlap
ChIP neural progenitor cell ENCFF018MKA 509 bp overlap
ChIP neural progenitor cell ENCFF018MKA 418 bp overlap
ChIP neural progenitor cell ENCFF472NFV 509 bp overlap
ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 231 bp overlap
EZH2_phosphoT487 1 dataset
ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 428 bp overlap
FERD3L 1 dataset
Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 323 bp overlap
GATA6 2 datasets
ChIP DE_D1 S41-DE-d1-GATA6-exp2 322 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 312 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 314 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 209 bp overlap
HAND2 1 dataset
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 193 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 261 bp overlap
HNRNPLL 1 dataset
ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 199 bp overlap
JARID2 6 datasets
ChIP AMIPS6 GSE48516.JARID2.AMIPS6 357 bp overlap
ChIP AMIPS8 GSE48516.JARID2.AMIPS8 431 bp overlap
ChIP EDOMIPS2 GSE48516.JARID2.EDOMIPS2 429 bp overlap
ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 377 bp overlap
ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 478 bp overlap
ChIP UTEIPS4 GSE48516.JARID2.UTEIPS4 393 bp overlap
JUN 2 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 319 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 305 bp overlap
KDM5B 2 datasets
ChIP HCC2157 GSE46055.KDM5B.HCC2157 131 bp overlap
ChIP Hep-G2 ENCSR227MRE.KDM5B.Hep-G2 167 bp overlap
KLF1 1 dataset
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
KLF10 1 dataset
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
KLF11 1 dataset
Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap
KLF12 1 dataset
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
KLF13 1 dataset
Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap
KLF14 1 dataset
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
KLF15 2 datasets
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
KLF16 1 dataset
Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap
KLF2 1 dataset
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
KLF4 1 dataset
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
KLF5 1 dataset
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
KLF7 1 dataset
Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap
MAX 1 dataset
ChIP H1 ENCFF914VQY 123 bp overlap
MECOM 1 dataset
ChIP SKH1_CEBPA-ER GSE102697.MECOM.SKH1_CEBPA-ER 164 bp overlap
MED1 2 datasets
ChIP SGBS GSE64233.MED1.SGBS 238 bp overlap
ChIP SGBS_TNF GSE64233.MED1.SGBS_TNF 111 bp overlap
MEIS1 1 dataset
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MSC 1 dataset
Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap
MYCN 4 datasets
ChIP BE2C GSE80151.MYCN.BE2C 241 bp overlap
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 352 bp overlap
ChIP SK-N-BE2-C GSE94822.MYCN.SK-N-BE2-C 160 bp overlap
ChIP SK-N-BE2-C GSE80151.MYCN.SK-N-BE2-C 241 bp overlap
MYF5 1 dataset
Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap
MYF6 1 dataset
Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap
MYOD1 1 dataset
Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap
MYOG 1 dataset
Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap
NANOG 2 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 447 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 202 bp overlap
NFIA 1 dataset
Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap
NFIC 1 dataset
Motif DE_12h DE_12h-NFIC_MA0161.3 7 bp overlap
NFIX 1 dataset
Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap
NHLH1 1 dataset
Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap
NRF1 1 dataset
ChIP H1 ENCFF582PEJ 245 bp overlap
Neurod2 1 dataset
Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap
OGG1 4 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 363 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 357 bp overlap
ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 323 bp overlap
ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 316 bp overlap
Olig2 1 dataset
Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap
PATZ1 1 dataset
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
PCGF2 1 dataset
ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 159 bp overlap
POU4F2 1 dataset
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 130 bp overlap
POU5F1 4 datasets
ChIP BG03 GSE21614.POU5F1.BG03 197 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 461 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 281 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 172 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 305 bp overlap
PTBP1 2 datasets
ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 147 bp overlap
ChIP Hep-G2 GSE120104.PTBP1.Hep-G2 147 bp overlap
Ptf1A 1 dataset
Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 229 bp overlap
RBM39 1 dataset
ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 191 bp overlap
RBPJ 2 datasets
ChIP HCC1599 GSE116871.RBPJ.HCC1599 299 bp overlap
ChIP HCC1599_GSI GSE116871.RBPJ.HCC1599_GSI 265 bp overlap
RELA 2 datasets
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 291 bp overlap
ChIP SGBS GSE64233.RELA.SGBS 88 bp overlap
RNF2 1 dataset
ChIP H1 ENCFF239FFS 509 bp overlap
RUNX1T1 1 dataset
ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 168 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 405 bp overlap
SCRT2 1 dataset
Motif DE_12h DE_12h-SCRT2_MA0744.3 10 bp overlap
SETDB1 1 dataset
ChIP WN8532 GSE36579.SETDB1.WN8532 148 bp overlap
SIN3A 1 dataset
ChIP WA01 ENCSR000EBO.SIN3A.WA01 155 bp overlap
SIRT6 1 dataset
ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 189 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 348 bp overlap
SOX2 1 dataset
ChIP RENVM GSE49404.SOX2.RENVM 178 bp overlap
SP1 2 datasets
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
ChIP WTC11 ENCFF688PEU 411 bp overlap
SP2 1 dataset
Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap
SP3 1 dataset
Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap
SP4 1 dataset
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
SP8 1 dataset
Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap
SP9 1 dataset
Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap
STAT3 1 dataset
ChIP HCC1187 GSE152203.STAT3.HCC1187 262 bp overlap
SUZ12 7 datasets
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 509 bp overlap
ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 175 bp overlap
ChIP H1 ENCFF507HGF 271 bp overlap
ChIP H1 ENCFF881NFR 509 bp overlap
ChIP K-562 ENCSR000AUC.SUZ12.K-562 183 bp overlap
ChIP WA01 ENCSR000ATS.SUZ12.WA01 357 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 381 bp overlap
TBP 1 dataset
ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 257 bp overlap
TCF12 2 datasets
ChIP WA01 ENCSR000BIT.TCF12.WA01 142 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 109 bp overlap
TFAP2A 1 dataset
Motif DE_12h DE_12h-TFAP2A_MA0872.1 13 bp overlap
TFAP2B 1 dataset
Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap
TFAP2C 3 datasets
Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 337 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 321 bp overlap
TFAP4 1 dataset
Motif DE_12h DE_12h-TFAP4_MA0691.1 10 bp overlap
TFAP4::FLI1 1 dataset
Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap
TGIF2 1 dataset
ChIP WTC11 ENCFF649SHI 330 bp overlap
THAP1 1 dataset
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 147 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 147 bp overlap
Tcf12 1 dataset
Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap
Tcf21 1 dataset
Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap
Twist2 1 dataset
Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap
ZBTB18 1 dataset
Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap
ZBTB48 2 datasets
ChIP U2OS GSE96776.ZBTB48.U2OS 356 bp overlap
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 360 bp overlap
ZEB1 1 dataset
ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 134 bp overlap
ZNF148 1 dataset
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
ZNF213 2 datasets
Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap
Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap
ZNF281 1 dataset
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
ZNF331 2 datasets
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
ZNF341 1 dataset
Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap
ZNF449 1 dataset
Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap
ZNF454 1 dataset
Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap
ZNF512 2 datasets
ChIP K-562 ENCSR591CCL.ZNF512.K-562 58 bp overlap
ChIP WTC11 ENCFF086TTM 275 bp overlap
ZNF513 2 datasets
ChIP HEK293 ENCFF457TCC 192 bp overlap
ChIP HEK293 ENCSR503DPC.ZNF513.HEK293 143 bp overlap
ZNF582 1 dataset
Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 157 bp overlap
Zfp335 1 dataset
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
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