chr1 : 3,674,548 – 3,675,046

498 bp 98 TFs 1 linked gene

This 498 bp open chromatin element is linked to TP73 and is bound by 98 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TP73		270 bp	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

AGO1 1 dataset

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 59 bp overlap

AR 1 dataset

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 233 bp overlap

ARID1B 1 dataset

ChIP MCF-7_shJUN GSE128445.ARID1B.MCF-7_shJUN 279 bp overlap

ASH2L 2 datasets

ChIP GM12878 ENCSR849WCQ.ASH2L.GM12878 106 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 459 bp overlap

ATF3 1 dataset

ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 172 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 381 bp overlap

BHLHE40 1 dataset

ChIP GM12878 ENCSR517QHU.BHLHE40.GM12878 52 bp overlap

BRD4 11 datasets

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 337 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 403 bp overlap

ChIP CLL_patient3_4h_CpG_BET GSE109411.BRD4.CLL_patient3_4h_CpG_BET 300 bp overlap

ChIP CLL_patient4_4h_CpG_BET GSE109411.BRD4.CLL_patient4_4h_CpG_BET 349 bp overlap

ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 358 bp overlap

ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 266 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 54 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 359 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 348 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 306 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 299 bp overlap

CHD1 1 dataset

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 95 bp overlap

CHD4 1 dataset

ChIP GM12878 ENCSR751CJG.CHD4.GM12878 128 bp overlap

CREB1 1 dataset

ChIP MDA-MB-134-VI GSE109103.CREB1.MDA-MB-134-VI 191 bp overlap

CTCF 2 datasets

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 204 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 275 bp overlap

DNMT3B 1 dataset

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 245 bp overlap

DPF2 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.DPF2.BIN-67_lentivirus-SMARCA4-K785R 203 bp overlap

E2F1 1 dataset

ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 163 bp overlap

EGR1 1 dataset

ChIP A-375 GSE116190.EGR1.A-375 397 bp overlap

ELF1 1 dataset

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 136 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 179 bp overlap

ESR1 4 datasets

ChIP Ishikawa_DMSO GSE132426.ESR1.Ishikawa_DMSO 461 bp overlap

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 429 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 260 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 243 bp overlap

ETV4 1 dataset

ChIP T-47D GSE129803.ETV4.T-47D 222 bp overlap

EZH2 1 dataset

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 308 bp overlap

FOXP1 2 datasets

ChIP WTC11 ENCFF338WGC 366 bp overlap

ChIP WTC11 ENCFF338WGC 458 bp overlap

GATAD2B 1 dataset

ChIP GM12878 ENCFF781IAU 291 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 276 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 365 bp overlap

GLIS2 2 datasets

ChIP HEK293 ENCFF446EIF 322 bp overlap

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 273 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 498 bp overlap

GRHL2 3 datasets

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 314 bp overlap

ChIP OVCA429 GSE71018.GRHL2.OVCA429 418 bp overlap

ChIP OVCAR-3 GSE71018.GRHL2.OVCAR-3 174 bp overlap

GTF2F1 1 dataset

ChIP GM12878 ENCSR769ZTN.GTF2F1.GM12878 101 bp overlap

HDGF 1 dataset

ChIP GM12878 ENCFF653WYI 99 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 392 bp overlap

HIC1 1 dataset

ChIP HEK293 ENCSR803GYT.HIC1.HEK293 242 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 105 bp overlap

JARID2 1 dataset

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 174 bp overlap

JUN 1 dataset

ChIP Karpas-299 GSE151413.JUN.Karpas-299 247 bp overlap

KDM5B 3 datasets

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 114 bp overlap

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 141 bp overlap

ChIP T-47D GSE46055.KDM5B.T-47D 145 bp overlap

KLF3 1 dataset

ChIP keratinocyte GSE140991.KLF3.keratinocyte 295 bp overlap

KMT2A 1 dataset

ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 100 bp overlap

LARP7 1 dataset

ChIP GM12878 ENCFF513CEX 318 bp overlap

MAF1 1 dataset

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 163 bp overlap

MAX 4 datasets

ChIP Ishikawa ENCSR000BTY.MAX.Ishikawa 119 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 409 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 490 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 96 bp overlap

MAZ 1 dataset

ChIP IMR-90 ENCSR000EFF.MAZ.IMR-90 197 bp overlap

MED1 5 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 400 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 336 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 325 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 362 bp overlap

ChIP VCaP GSE148358.MED1.VCaP 219 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 289 bp overlap

MYC 2 datasets

ChIP NCI-H128 GSE41105.MYC.NCI-H128 255 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 438 bp overlap

MYCN 1 dataset

ChIP LNCaP_DHT GSE117304.MYCN.LNCaP_DHT 271 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 498 bp overlap

NELFE 1 dataset

ChIP HCT-116_KAP1-KO GSE132705.NELFE.HCT-116_KAP1-KO 269 bp overlap

NEUROG2 3 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 281 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 158 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 103 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 57 bp overlap

NR2F1 1 dataset

ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 235 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 379 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 355 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 279 bp overlap

PATZ1 1 dataset

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 272 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 359 bp overlap

PHF8 1 dataset

ChIP WA01 ENCSR000ATK.PHF8.WA01 301 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 326 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 334 bp overlap

POU2F1 3 datasets

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 138 bp overlap

ChIP T-47D GSE148277.POU2F1.T-47D 276 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 498 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 169 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 202 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 225 bp overlap

PTBP1 1 dataset

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 170 bp overlap

RBBP4 1 dataset

ChIP SCMC GSE155861.RBBP4.SCMC 187 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 435 bp overlap

RELA 2 datasets

ChIP GM12878 ENCSR000EAG.RELA.GM12878 60 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 342 bp overlap

REST 1 dataset

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 170 bp overlap

RYBP 1 dataset

ChIP WA01 GSE104690.RYBP.WA01 222 bp overlap

SMARCA4 3 datasets

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 327 bp overlap

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 271 bp overlap

ChIP NCI-H1703 GSE121755.SMARCA4.NCI-H1703 294 bp overlap

SMARCA5 2 datasets

ChIP GM12878 ENCFF327LDR 346 bp overlap

ChIP GM12878 ENCSR706YUH.SMARCA5.GM12878 372 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 348 bp overlap

SNAI2 1 dataset

ChIP PC-9_1DF GSE131687.SNAI2.PC-9_1DF 319 bp overlap

SOX2 2 datasets

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 221 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 167 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 93 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 299 bp overlap

SS18 1 dataset

ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 342 bp overlap

STAT1 1 dataset

ChIP GM12878 ENCSR332EYT.STAT1.GM12878 245 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 231 bp overlap

ChIP K-562 ENCSR000AUC.SUZ12.K-562 213 bp overlap

TAF15 1 dataset

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 180 bp overlap

TBP 1 dataset

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 244 bp overlap

TCF3 2 datasets

ChIP GM12878 ENCSR000BQT.TCF3.GM12878 104 bp overlap

ChIP NPC GSE154479.TCF3.NPC 344 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 184 bp overlap

TEAD4 13 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 263 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP Ishikawa ENCSR000BSW.TEAD4.Ishikawa 162 bp overlap

ChIP MCF-7_BLRP_WT_E2 GSE125594.TEAD4.MCF-7_BLRP_WT_E2 214 bp overlap

ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 291 bp overlap

ChIP MCF-7_E2 GSE125594.TEAD4.MCF-7_E2 234 bp overlap

ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 416 bp overlap

ChIP PC-9_1DF_DMSO GSE131687.TEAD4.PC-9_1DF_DMSO 378 bp overlap

ChIP PC-9_2DF GSE131687.TEAD4.PC-9_2DF 430 bp overlap

ChIP PC-9_2DF_DMSO GSE131687.TEAD4.PC-9_2DF_DMSO 396 bp overlap

ChIP SNU-216 GSE44416.TEAD4.SNU-216 168 bp overlap

ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 280 bp overlap

ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 383 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 86 bp overlap

TP63 1 dataset

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 141 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 186 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

USF1 1 dataset

ChIP K562 ENCFF202SFC 84 bp overlap

WDR5 1 dataset

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 218 bp overlap

YY1AP1 4 datasets

ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 477 bp overlap

ChIP PC-9_1DF_DMSO GSE131687.YY1AP1.PC-9_1DF_DMSO 407 bp overlap

ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 491 bp overlap

ChIP PC-9_2DF_DMSO GSE131687.YY1AP1.PC-9_2DF_DMSO 300 bp overlap

ZBTB7A 2 datasets

ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 308 bp overlap

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 318 bp overlap

ZEB1 2 datasets

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 498 bp overlap

ChIP MIA-PaCa-2 GSE88734.ZEB1.MIA-PaCa-2 159 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 429 bp overlap

ZFX 1 dataset

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 448 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 370 bp overlap

ZNF141 1 dataset

ChIP HEK293T GSE78099.ZNF141.HEK293T 134 bp overlap

ZNF143 1 dataset

ChIP MCF-7 GSE76454.ZNF143.MCF-7 200 bp overlap

ZNF217 1 dataset

ChIP GM12878 ENCSR764CZW.ZNF217.GM12878 109 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 57 bp overlap

ZNF592 1 dataset

ChIP GM12878 ENCFF818ABS 101 bp overlap

ZNF687 1 dataset

ChIP GM12878 ENCFF233SGE 210 bp overlap