chr1:110,067,875–110,068,495

chr1 : 110,067,875 – 110,068,495

620 bp 113 TFs 7 linked genes

This 620 bp open chromatin element is linked to 7 target genes and is bound by 113 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ALX3		2.2 kb	Proximal	Proximity
ENSG00000258634		9.5 kb	Proximal	Proximity
STRIP1		33.5 kb	Distal	Multiome
AHCYL1		83.4 kb	Distal	Multiome
KCNC4		142.2 kb	Distal	Multiome
RBM15-AS1		271.1 kb	Distal	Multiome
RBM15		271.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

113 transcription factors

AGO1 4 datasets

ChIP K-562 ENCSR641BSL.AGO1.K-562 365 bp overlap

ChIP K-562 GSE120104.AGO1.K-562 328 bp overlap

ChIP K-562 ENCSR641BSL.AGO1.K-562 203 bp overlap

ChIP K-562 GSE120104.AGO1.K-562 177 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 135 bp overlap

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 230 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 417 bp overlap

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 399 bp overlap

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 590 bp overlap

Ahr::Arnt 1 dataset

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BACH1 1 dataset

ChIP WA01 ENCSR000EBQ.BACH1.WA01 154 bp overlap

BCOR 2 datasets

ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 620 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 169 bp overlap

ChIP GM12878 ENCSR469WII.BMI1.GM12878 233 bp overlap

BRD1 2 datasets

ChIP HUES-64 GSE104059.BRD1.HUES-64 134 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 303 bp overlap

BRD4 13 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 192 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 278 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 555 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 265 bp overlap

ChIP MCF-7 GSE55921.BRD4.MCF-7 231 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 620 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 268 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 588 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 68 bp overlap

ChIP hESC GSE33281.BRD4.hESC 66 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 611 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 504 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 469 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 166 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 482 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 514 bp overlap

ChIP H1 ENCFF095JHA 173 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 344 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 113 bp overlap

ChIP H1 ENCFF998XEK 479 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 313 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 361 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 468 bp overlap

CTCF 4 datasets

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 321 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 114 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 495 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 112 bp overlap

E2F6 2 datasets

Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 534 bp overlap

ChIP ProEs GSE59087.EED.ProEs 620 bp overlap

EP300 1 dataset

ChIP tibial nerve ENCFF346AYA 161 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 194 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 203 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 157 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 185 bp overlap

ESR1 5 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 459 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 247 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 585 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 620 bp overlap

ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 277 bp overlap

ETS1 3 datasets

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 209 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 209 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 209 bp overlap

EZH2 24 datasets

ChIP B cell ENCFF803EMO 184 bp overlap

ChIP GM23248 ENCFF404ZHM 93 bp overlap

ChIP GM23338 ENCFF613YON 620 bp overlap

ChIP GM23338 ENCFF886DXX 620 bp overlap

ChIP H1 ENCFF232NZA 620 bp overlap

ChIP astrocyte ENCFF365JTP 620 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 202 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 87 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 203 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 289 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 620 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 383 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 54 bp overlap

ChIP fibroblast of lung ENCFF479BAW 70 bp overlap

ChIP hESC GSE113817.EZH2.hESC 620 bp overlap

ChIP hESC_KO GSE113817.EZH2.hESC_KO 389 bp overlap

ChIP hepatocyte ENCFF118DKH 134 bp overlap

ChIP hepatocyte ENCFF552DZB 620 bp overlap

ChIP keratinocyte ENCFF070STK 259 bp overlap

ChIP mammary epithelial cell ENCFF224GAI 285 bp overlap

ChIP neural cell ENCFF610EPB 400 bp overlap

ChIP neural cell ENCFF610EPB 342 bp overlap

ChIP neural progenitor cell ENCFF018MKA 620 bp overlap

ChIP neural progenitor cell ENCFF472NFV 620 bp overlap

EZH2_phosphoT487 1 dataset

ChIP DOHH2 ENCSR562NOP.EZH2_phosphoT487.DOHH2 531 bp overlap

FEZF2 2 datasets

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 269 bp overlap

FOXA1 1 dataset

ChIP prostate_P13_T GSE130408.FOXA1.prostate_P13_T 166 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 239 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 499 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 371 bp overlap

GATA2 2 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 275 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 578 bp overlap

HDAC6 2 datasets

ChIP GM12878 ENCFF918SGD 485 bp overlap

ChIP GM12878 ENCSR933EYC.HDAC6.GM12878 561 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 524 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 225 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 619 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 79 bp overlap

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 51 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 185 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 533 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 620 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 203 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 475 bp overlap

KDM5B 1 dataset

ChIP MCF-7 GSE46055.KDM5B.MCF-7 188 bp overlap

KMT2A 3 datasets

ChIP MV4-11 GSE83671.KMT2A.MV4-11 122 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 441 bp overlap

ChIP blood_cord GSE83671.KMT2A.blood_cord 160 bp overlap

MBD2 2 datasets

ChIP HeLa GSE41006.MBD2.HeLa 149 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 150 bp overlap

MLLT3 1 dataset

ChIP HSPC_MLLT3-virus GSE111482.MLLT3.HSPC_MLLT3-virus 144 bp overlap

ChIP CD34 GSE85488.MYC.CD34 135 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 262 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 563 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 620 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 207 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 407 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 511 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 160 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 620 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 616 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 253 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 472 bp overlap

ChIP retina_pigment GSE60024.PAX6.retina_pigment 74 bp overlap

PCGF2 1 dataset

ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 392 bp overlap

PDX1 2 datasets

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 255 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 216 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 171 bp overlap

POLR2A 6 datasets

ChIP neural cell ENCFF604SPB 230 bp overlap

ChIP sigmoid colon ENCFF725QFT 119 bp overlap

ChIP sigmoid colon ENCFF748YVT 172 bp overlap

ChIP spleen ENCFF446ZGT 331 bp overlap

ChIP spleen ENCFF706IUS 620 bp overlap

ChIP vagina ENCFF384GAB 195 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 429 bp overlap

ChIP K562 ENCFF648YPL 467 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 400 bp overlap

POU5F1 6 datasets

ChIP BG03 GSE21614.POU5F1.BG03 287 bp overlap

ChIP BG03 GSE21614.POU5F1.BG03 158 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 568 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 408 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 552 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 161 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 570 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 294 bp overlap

PRDM15 2 datasets

ChIP WTC11 ENCFF108TMF 401 bp overlap

ChIP WTC11 ENCFF108TMF 292 bp overlap

RAD21 1 dataset

ChIP hiPSC_IID12 GSE106870.RAD21.hiPSC_IID12 142 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 243 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 620 bp overlap

RELA 3 datasets

ChIP HEK293_30_min GSE89017.RELA.HEK293_30_min 465 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 349 bp overlap

ChIP SGBS GSE64233.RELA.SGBS 90 bp overlap

RNF2 2 datasets

ChIP H1 ENCFF239FFS 620 bp overlap

ChIP HUES-64 GSE104059.RNF2.HUES-64 64 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 407 bp overlap

SETDB1 2 datasets

ChIP K-562 ENCSR000EWI.SETDB1.K-562 149 bp overlap

ChIP K-562 ENCSR000EWI.SETDB1.K-562 303 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 120 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 179 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 306 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 65 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 142 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 290 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 285 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

SMARCA4 2 datasets

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 165 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 163 bp overlap

SMARCB1 1 dataset

ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 238 bp overlap

SMC1 3 datasets

ChIP DKO GSE131606.SMC1.DKO 149 bp overlap

ChIP IMR-90_G GSE118494.SMC1.IMR-90_G 378 bp overlap

ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 134 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 125 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 620 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 620 bp overlap

STAT1 1 dataset

ChIP CD14_INFG_LPS GSE43036.STAT1.CD14_INFG_LPS 175 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 441 bp overlap

SUZ12 7 datasets

ChIP Aska-SS GSE108025.SUZ12.Aska-SS 186 bp overlap

ChIP GM12878 ENCFF498QAM 250 bp overlap

ChIP H1 ENCFF507HGF 271 bp overlap

ChIP H1 ENCFF507HGF 226 bp overlap

ChIP H1 ENCFF881NFR 620 bp overlap

ChIP NT2/D1 ENCFF574SXS 348 bp overlap

ChIP ProEs GSE59087.SUZ12.ProEs 209 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 400 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 337 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 446 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 125 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 290 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 350 bp overlap

TCF7L2 1 dataset

ChIP CD34_PROG_BIO GSE29194.TCF7L2.CD34_PROG_BIO 91 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 154 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0872.1 13 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 227 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 482 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 205 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 553 bp overlap

TRIM28 3 datasets

ChIP AF22 GSE84259.TRIM28.AF22 348 bp overlap

ChIP AF22 GSE84259.TRIM28.AF22 173 bp overlap

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 581 bp overlap

ZBTB33 2 datasets

ChIP K562 ENCFF427SDV 505 bp overlap

ChIP K562 ENCFF427SDV 382 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 620 bp overlap

ZFP36 1 dataset

ChIP GM12878 ENCSR900XDB.ZFP36.GM12878 78 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 620 bp overlap

ChIP HeLa-S3 ENCSR887MXT.ZHX1.HeLa-S3 172 bp overlap

ZNF2 2 datasets

ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 149 bp overlap

ChIP HEK293T GSE78099.ZNF2.HEK293T 532 bp overlap

ZNF213 2 datasets

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

Motif DE_24h DE_24h-ZNF213_MA2121.1 12 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 185 bp overlap

ZNF512 1 dataset

ChIP WTC11 ENCFF086TTM 236 bp overlap

ZNF684 1 dataset

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

Zfp961 1 dataset

Motif DE_12h DE_12h-Zfp961_MA2126.1 8 bp overlap