chr1:11,682,348–11,682,757

chr1 : 11,682,348 – 11,682,757

409 bp 94 TFs 12 linked genes

This 409 bp open chromatin element is linked to 12 target genes and is bound by 94 transcription factors.

Linked Genes

12 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MAD2L2		1.2 kb	Proximal	Proximity
DRAXIN		9.0 kb	Proximal	Proximity
FBXO6		18.5 kb	Distal	Multiome
FBXO44		27.8 kb	Distal	Multiome
FBXO2		28.3 kb	Distal	Multiome
AGTRAP		53.4 kb	Distal	Multiome
MTHFR		120.7 kb	Distal	Multiome
CLCN6		123.5 kb	Distal	Multiome
DISP3		203.5 kb	Distal	Multiome
KIAA2013		243.7 kb	Distal	Multiome
PLOD1		252.0 kb	Distal	Multiome
MFN2		297.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

94 transcription factors

ChIP VCaP GSE148358.AR.VCaP 253 bp overlap

ChIP prostate_2752_T GSE130408.AR.prostate_2752_T 136 bp overlap

ChIP prostate_2815_T GSE130408.AR.prostate_2815_T 107 bp overlap

ChIP prostate_P23_T GSE130408.AR.prostate_P23_T 187 bp overlap

ASH2L 2 datasets

ChIP VCaP GSE60841.ASH2L.VCaP 265 bp overlap

ChIP VCaP_R1881 GSE60841.ASH2L.VCaP_R1881 175 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 409 bp overlap

BAF155 2 datasets

ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 221 bp overlap

ChIP VCaP_shERG GSE110655.BAF155.VCaP_shERG 172 bp overlap

BCL11A 3 datasets

ChIP H1 ENCFF836SSR 177 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 143 bp overlap

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 119 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 409 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 190 bp overlap

BRD4 4 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 119 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 81 bp overlap

ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 147 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 265 bp overlap

CCAR2 1 dataset

ChIP Hep-G2 ENCSR247XFV.CCAR2.Hep-G2 74 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 120 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 409 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 288 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 315 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 368 bp overlap

CREB5 1 dataset

ChIP LNCaP GSE137775.CREB5.LNCaP 220 bp overlap

ChIP WTC11 ENCFF209ZUE 354 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 226 bp overlap

EBF1 4 datasets

ChIP ASC GSE54889.EBF1.ASC 131 bp overlap

ChIP GM12878 ENCFF167CZS 213 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 208 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 178 bp overlap

EGR1 2 datasets

ChIP H1 ENCFF451BLH 261 bp overlap

ChIP WA01 ENCSR000BJA.EGR1.WA01 125 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 165 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 212 bp overlap

ChIP hESC GSE17917.EP300.hESC 299 bp overlap

ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 95 bp overlap

ChIP VCaP_R1881 GSE49091.ERG.VCaP_R1881 169 bp overlap

ESR1 4 datasets

ChIP Ishikawa ENCSR000BKL.ESR1.Ishikawa 202 bp overlap

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 283 bp overlap

ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 155 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 93 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 213 bp overlap

EZH2 4 datasets

ChIP SF8628 GSE94834.EZH2.SF8628 409 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 104 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 288 bp overlap

ChIP hESC GSE113817.EZH2.hESC 240 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 233 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 238 bp overlap

FOXA1 4 datasets

ChIP 22Rv1 GSE96652.FOXA1.22Rv1 313 bp overlap

ChIP LNCaP-C4-2B_CST GSE123618.FOXA1.LNCaP-C4-2B_CST 135 bp overlap

ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 242 bp overlap

ChIP prostate_P19_T GSE130408.FOXA1.prostate_P19_T 194 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 304 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 367 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 364 bp overlap

GATA6 4 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 278 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 307 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 398 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 291 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 271 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 290 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 357 bp overlap

GRHL2 5 datasets

ChIP LNCaP GSE80256.GRHL2.LNCaP 153 bp overlap

ChIP MCF-7 GSE109820.GRHL2.MCF-7 217 bp overlap

ChIP MCF-7 GSE99680.GRHL2.MCF-7 195 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 212 bp overlap

ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 230 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 292 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 169 bp overlap

ChIP K562 ENCFF682FBH 177 bp overlap

HNF4A 2 datasets

ChIP liver ENCFF354NRH 202 bp overlap

ChIP liver ERP002306.HNF4A.liver 85 bp overlap

HOXB13 7 datasets

ChIP G-401 GSE65381.HOXB13.G-401 181 bp overlap

ChIP prostate-cancer_PDX_141 GSE130408.HOXB13.prostate-cancer_PDX_141 71 bp overlap

ChIP prostate-cancer_PDX_170-2 GSE130408.HOXB13.prostate-cancer_PDX_170-2 105 bp overlap

ChIP prostate_2483_T GSE130408.HOXB13.prostate_2483_T 157 bp overlap

ChIP prostate_P19_T GSE130408.HOXB13.prostate_P19_T 191 bp overlap

ChIP prostate_P1_T GSE130408.HOXB13.prostate_P1_T 174 bp overlap

ChIP prostate_P29_T GSE130408.HOXB13.prostate_P29_T 226 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 190 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 175 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 364 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 409 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 406 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 409 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 409 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 365 bp overlap

JUND 2 datasets

ChIP H1 ENCFF468JZD 231 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 117 bp overlap

KLF4 2 datasets

ChIP WA09 GSE105028.KLF4.WA09 282 bp overlap

ChIP WA09_heat-shock GSE105028.KLF4.WA09_heat-shock 296 bp overlap

KMT2A 2 datasets

ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 70 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 409 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 286 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 255 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 257 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 386 bp overlap

ChIP H1 ENCFF747ZPQ 66 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 409 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 409 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 382 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 409 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 409 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 409 bp overlap

ChIP hESC GSE18292.NANOG.hESC 291 bp overlap

ChIP hESC GSE20650.NANOG.hESC 284 bp overlap

NIPBL 6 datasets

ChIP WA09 GSE105028.NIPBL.WA09 409 bp overlap

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 409 bp overlap

ChIP hESC GSE64758.NIPBL.hESC 403 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 302 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 405 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 377 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 314 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 332 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 409 bp overlap

PHIP 2 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 77 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 154 bp overlap

POLR2A 4 datasets

ChIP GM23338 ENCFF450WCS 401 bp overlap

ChIP H1 ENCFF566JSR 225 bp overlap

ChIP H1 ENCFF770YBQ 283 bp overlap

ChIP H1 ENCFF833NJP 195 bp overlap

POU5F1 12 datasets

ChIP BG03 GSE21614.POU5F1.BG03 170 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 378 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 409 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 409 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 381 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 351 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 358 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 281 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 409 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 270 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 319 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 363 bp overlap

RAD21 1 dataset

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 409 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 113 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 293 bp overlap

ChIP K562 ENCFF607OWI 88 bp overlap

ChIP H1 ENCFF429RUE 213 bp overlap

RXRA 2 datasets

ChIP H1 ENCFF570NHK 201 bp overlap

ChIP WA01 ENCSR000BJW.RXRA.WA01 143 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 201 bp overlap

SIN3A 4 datasets

ChIP H1 ENCFF042ZSL 313 bp overlap

ChIP H1 ENCFF042ZSL 409 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 303 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 107 bp overlap

ChIP WTC11 ENCFF891HYW 302 bp overlap

SMAD2 3 datasets

ChIP hESC GSE29422.SMAD2.hESC 149 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 333 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 406 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 409 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 409 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 409 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 384 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 384 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 398 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 318 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 375 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 399 bp overlap

SMAD3 6 datasets

ChIP BG03 GSE21614.SMAD3.BG03 283 bp overlap

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 316 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 225 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 172 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 393 bp overlap

ChIP hESC_DIFF_D1 GSE75297.SMAD3.hESC_DIFF_D1 237 bp overlap

SMAD4 1 dataset

ChIP hESC GSE29422.SMAD4.hESC 157 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-pos GSE122631.SMARCA2.NPC_K755R-pos 158 bp overlap

ChIP NPC_R1159Q GSE122631.SMARCA2.NPC_R1159Q 150 bp overlap

SMARCA4 4 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 119 bp overlap

ChIP WA09 GSE105028.SMARCA4.WA09 289 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 212 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 206 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 409 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 409 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 409 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 409 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 98 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 371 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 409 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 68 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 255 bp overlap

ChIP HEK293 ENCSR468IJT.SP7.HEK293 320 bp overlap

STAT3 1 dataset

ChIP MDA-MB-157_EtOH GSE85579.STAT3.MDA-MB-157_EtOH 371 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 314 bp overlap

TAF1 3 datasets

ChIP H1 ENCFF478SZO 325 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 177 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 120 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 242 bp overlap

ChIP hESC GSE122298.TBP.hESC 276 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 326 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 145 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 199 bp overlap

TCF12 3 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP Ishikawa ENCSR000BUV.TCF12.Ishikawa 198 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 400 bp overlap

ChIP NPC GSE154479.TCF3.NPC 406 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 361 bp overlap

TEAD4 4 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 409 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP Ishikawa ENCSR000BSW.TEAD4.Ishikawa 107 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 233 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 409 bp overlap

ChIP WA01 GSE99202.YAP1.WA01 271 bp overlap

ChIP ALL GSE145549.YY1.ALL 54 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 180 bp overlap

ZBTB20 1 dataset

ChIP HEK293 ENCFF524ADK 229 bp overlap

ZBTB42 1 dataset

ChIP HEK293 GSE76494.ZBTB42.HEK293 181 bp overlap

ZBTB44 2 datasets

ChIP HEK293 ENCFF560VPN 202 bp overlap

ChIP HEK293 ENCSR076STQ.ZBTB44.HEK293 146 bp overlap

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 396 bp overlap

ZFP91 4 datasets

ChIP K-562 ENCSR898XMH.ZFP91.K-562 300 bp overlap

ChIP K562 ENCFF185FKB 303 bp overlap

ChIP K562 ENCFF501CDP 213 bp overlap

ChIP K562 ENCFF501CDP 137 bp overlap

ChIP HEK293 ENCFF033NQQ 329 bp overlap

ZNF143 1 dataset

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 409 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 373 bp overlap

ZNF398 1 dataset

ChIP H9 GSE133630.ZNF398.H9 154 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 232 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 178 bp overlap

ZNF574 1 dataset

ChIP HEK293 GSE76494.ZNF574.HEK293 155 bp overlap