Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for KIAA2013. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = KIAA2013 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of KIAA2013, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr1:11,650,273–11,650,925 | 275.9 kb | Distal (>10kb) Multiome | 495 | |
| chr1:11,653,905–11,655,506 | 271.7 kb | Distal (>10kb) Multiome | 476 | |
| chr1:11,663,895–11,664,883 | 262.2 kb | Distal (>10kb) Multiome | 644 | |
| chr1:11,680,428–11,681,928 | 245.2 kb | Distal (>10kb) Multiome | 820 | |
| chr1:11,682,348–11,682,757 | 243.7 kb | Distal (>10kb) Multiome | 94 | |
| chr1:11,690,815–11,692,563 | 234.7 kb | Distal (>10kb) Multiome | 361 | |
| chr1:11,735,752–11,736,686 | 190.3 kb | Distal (>10kb) Multiome | 714 | |
| chr1:11,784,926–11,785,439 | 141.1 kb | Distal (>10kb) Multiome | 531 | |
| chr1:11,802,827–11,804,002 | 122.8 kb | Distal (>10kb) Multiome | 507 | |
| chr1:11,805,133–11,806,702 | 120.4 kb | Distal (>10kb) Multiome | 1034 | |
| chr1:11,876,145–11,876,721 | 50.0 kb | Distal (>10kb) Multiome | 56 | |
| chr1:11,907,175–11,910,389 | 18.0 kb | Distal (>10kb) Multiome | 1299 | |
| chr1:11,925,969–11,926,788 | 56 bp | At TSS Multiome | 632 | |
| chr1:11,934,261–11,935,008 | 8.2 kb | Proximal (<10kb) Multiome | 809 | |
| chr1:11,979,601–11,980,894 | 53.9 kb | Distal (>10kb) Multiome | 932 | |
| chr1:12,019,010–12,020,110 | 93.0 kb | Distal (>10kb) Multiome | 841 | |
| chr1:12,049,082–12,050,305 | 123.5 kb | Distal (>10kb) Multiome | 142 | |
| chr1:12,067,600–12,068,080 | 141.4 kb | Distal (>10kb) Multiome | 128 | |
| chr1:12,078,792–12,079,863 | 153.2 kb | Distal (>10kb) Multiome | 281 | |
| chr1:12,166,812–12,167,546 | 240.6 kb | Distal (>10kb) Multiome | 414 | |
| chr1:12,208,729–12,209,345 | 282.6 kb | Distal (>10kb) Multiome | 331 |
Genomic view of the KIAA2013 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.