chr22:39,179,438–39,180,229

chr22 : 39,179,438 – 39,180,229

791 bp 84 TFs 10 linked genes

This 791 bp open chromatin element is linked to 10 target genes and is bound by 84 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CBX7		27.1 kb	Distal	Multiome
PDGFB		63.3 kb	Distal	Multiome
APOBEC3G		102.4 kb	Distal	Multiome
APOBEC3F		138.8 kb	Distal	Multiome
RPL3		139.9 kb	Distal	Multiome+HiCAR
APOBEC3D		158.6 kb	Distal	Multiome
APOBEC3C		165.4 kb	Distal	Multiome
SYNGR1		170.3 kb	Distal	Multiome
TAB1		220.1 kb	Distal	Multiome
MGAT3		277.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

84 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 216 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 166 bp overlap

BCL11A 5 datasets

ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 100 bp overlap

ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 125 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 66 bp overlap

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 69 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 97 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 244 bp overlap

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 260 bp overlap

BRD3 2 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 181 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 195 bp overlap

BRD4 7 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 230 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 232 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 645 bp overlap

ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 254 bp overlap

ChIP SW480 GSE73319.BRD4.SW480 273 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 323 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 791 bp overlap

BRD9 2 datasets

ChIP G-401 GSE120234.BRD9.G-401 212 bp overlap

ChIP G-401 GSE120234.BRD9.G-401 485 bp overlap

CHD4 2 datasets

ChIP RH5 GSE155861.CHD4.RH5 223 bp overlap

ChIP RH5 GSE155861.CHD4.RH5 203 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 421 bp overlap

CTCF 7 datasets

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 150 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 200 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 146 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 100 bp overlap

ChIP endodermal cell ENCFF471YCZ 333 bp overlap

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 131 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 114 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF274GAT 302 bp overlap

ChIP BLaER1 ENCFF274GAT 194 bp overlap

ChIP BLaER1 ENCFF364PUR 184 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 144 bp overlap

ChIP SK-N-MC_SHFLI_96H GSE61944.ELF1.SK-N-MC_SHFLI_96H 208 bp overlap

ESRRA 2 datasets

ChIP K-562 ENCSR486IFJ.ESRRA.K-562 597 bp overlap

ChIP K562 ENCFF968PEP 465 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 128 bp overlap

FOXA1 1 dataset

ChIP LS180 GSE140533.FOXA1.LS180 63 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 173 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 195 bp overlap

GATA2 1 dataset

ChIP K-562 ENCSR000EWG.GATA2.K-562 130 bp overlap

GATA3 2 datasets

ChIP Kelly GSE65664.GATA3.Kelly 219 bp overlap

ChIP T-47D GSE51274.GATA3.T-47D 239 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 190 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 189 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 791 bp overlap

HAND2 1 dataset

ChIP Kelly GSE94822.HAND2.Kelly 118 bp overlap

HCFC1 1 dataset

ChIP Hep-G2 ENCSR529JYA.HCFC1.Hep-G2 161 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 230 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR711VWL.HDAC1.K-562 353 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 392 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 256 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 545 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 470 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 361 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 481 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 254 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 293 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 740 bp overlap

ChIP H1 ENCFF914VQY 318 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 236 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 276 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 334 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 223 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 171 bp overlap

MLLT1 1 dataset

ChIP K-562 ENCSR107GRP.MLLT1.K-562 211 bp overlap

ChIP K-562 ENCSR411UYA.MTA2.K-562 499 bp overlap

MTA3 2 datasets

ChIP K-562 ENCSR914NEI.MTA3.K-562 242 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 276 bp overlap

ChIP NCI-H128 GSE41105.MYC.NCI-H128 223 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 211 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 328 bp overlap

MYOD1 2 datasets

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 218 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 144 bp overlap

NCAPH2 2 datasets

ChIP RMG-I GSE120058.NCAPH2.RMG-I 316 bp overlap

ChIP RMG-I GSE120058.NCAPH2.RMG-I 226 bp overlap

NFKB1 2 datasets

ChIP HEK293T GSE129618.NFKB1.HEK293T 334 bp overlap

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 336 bp overlap

NFRKB 1 dataset

ChIP K-562 ENCSR657EOF.NFRKB.K-562 234 bp overlap

ChIP Hep-G2 ENCSR124APT.NFYA.Hep-G2 124 bp overlap

ChIP WTC11 ENCFF751ZTQ 149 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 500 bp overlap

Motif DE_24h DE_24h-OSR2_MA1646.2 8 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 212 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 370 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 265 bp overlap

RAD21 2 datasets

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 390 bp overlap

ChIP HepG2 ENCFF360ZSW 187 bp overlap

RBBP4 1 dataset

ChIP RH5 GSE155861.RBBP4.RH5 326 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 316 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 311 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 247 bp overlap

ChIP K-562 ENCSR772EEN.RELA.K-562 342 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 240 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 313 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 296 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 192 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 213 bp overlap

SMARCA4 2 datasets

ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 166 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 481 bp overlap

ChIP DKO GSE131606.SMC1.DKO 203 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 168 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 169 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 328 bp overlap

STAG1 1 dataset

ChIP Hep-G2 ENCSR167MTG.STAG1.Hep-G2 92 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 100 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 137 bp overlap

ChIP H1 ENCFF859IIO 347 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 244 bp overlap

ChIP hESC GSE122298.TBP.hESC 203 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 203 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 200 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 235 bp overlap

ChIP Hep-G2 ENCSR430JGJ.THRB.Hep-G2 168 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 187 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 188 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 231 bp overlap

ZBTB24 1 dataset

ChIP HCT-116 GSE111683.ZBTB24.HCT-116 328 bp overlap

ZBTB48 2 datasets

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 287 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 629 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 769 bp overlap

ChIP K-562 ENCSR920ASP.ZFX.K-562 243 bp overlap

ChIP K-562 ENCSR920ASP.ZFX.K-562 213 bp overlap

ChIP K562 ENCFF169LZT 651 bp overlap

ChIP K562 ENCFF536AJO 716 bp overlap

ChIP K562 ENCFF536AJO 631 bp overlap

Motif DE_24h DE_24h-ZIM3_MA1709.2 11 bp overlap

ZKSCAN1 1 dataset

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 116 bp overlap

ZNF189 3 datasets

Motif DE_24h DE_24h-ZNF189_MA1725.2 9 bp overlap

ChIP HEK293 ENCFF638TIB 133 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 237 bp overlap

ZNF24 2 datasets

ChIP K-562 ENCSR099NCH.ZNF24.K-562 201 bp overlap

ChIP K562 ENCFF877JCX 121 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 245 bp overlap

ZNF282 1 dataset

Motif DE_24h DE_24h-ZNF282_MA1154.2 15 bp overlap

ZNF341 3 datasets

ChIP HEK293 ENCFF944VMC 278 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 598 bp overlap

ChIP HEK293 GSE76494.ZNF341.HEK293 152 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 150 bp overlap