chr17:8,310,033–8,310,555

chr17 : 8,310,033 – 8,310,555

522 bp 98 TFs 11 linked genes

This 522 bp open chromatin element is linked to 11 target genes and is bound by 98 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ARHGEF15		at TSS	At TSS	Proximity
RANGRF		21.6 kb	Distal	Multiome
PFAS		61.0 kb	Distal	Multiome
CTC1		62.2 kb	Distal	Multiome
KRBA2		66.4 kb	Distal	Multiome
RPL26		72.9 kb	Distal	Multiome
AURKB		99.7 kb	Distal	Multiome
NDEL1		125.6 kb	Distal	Multiome
TMEM107		133.9 kb	Distal	Multiome
VAMP2		147.3 kb	Distal	Multiome
PER1		153.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 310 bp overlap

BCL11A 1 dataset

ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 67 bp overlap

BRD3 2 datasets

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 333 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 141 bp overlap

BRD4 2 datasets

ChIP HUVEC-C_modGFP GSE93030.BRD4.HUVEC-C_modGFP 437 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 227 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 221 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 278 bp overlap

ChIP K562 ENCFF673OEZ 411 bp overlap

ChIP SET-2 GSE65138.CDK8.SET-2 253 bp overlap

ChIP K-562 ENCSR077DKV.CREM.K-562 161 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 444 bp overlap

CTCF 5 datasets

ChIP anterior-temporal-cortex_adult GSE116825.CTCF.anterior-temporal-cortex_adult 317 bp overlap

ChIP coronary-artery ENCSR175FLL.CTCF.coronary-artery 116 bp overlap

ChIP heart_left-ventricle ENCSR544APK.CTCF.heart_left-ventricle 256 bp overlap

ChIP lung_left_upper-lobe ENCSR027FSZ.CTCF.lung_left_upper-lobe 303 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli GSE126755.CTCF.peripheral-blood-neutrophil_Ecoli 222 bp overlap

DIDO1 1 dataset

ChIP K-562 ENCSR167JBG.DIDO1.K-562 411 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.DPF2.BIN-67_lentivirus-SMARCA4 248 bp overlap

ChIP ProEs GSE59087.EED.ProEs 128 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 266 bp overlap

EP300 2 datasets

ChIP pulmonary-artery_endothelial-cell_siCtrl GSE89786.EP300.pulmonary-artery_endothelial-cell_siCtrl 231 bp overlap

ChIP pulmonary-artery_endothelial-cell_siPFKFB3 GSE89786.EP300.pulmonary-artery_endothelial-cell_siPFKFB3 286 bp overlap

ERG 20 datasets

ChIP HAEC GSE89970.ERG.HAEC 179 bp overlap

ChIP HUVEC-C GSE124891.ERG.HUVEC-C 208 bp overlap

ChIP HUVEC-C GSE128382.ERG.HUVEC-C 160 bp overlap

ChIP aortic-endothelial-cell_D1 GSE139377.ERG.aortic-endothelial-cell_D1 183 bp overlap

ChIP aortic-endothelial-cell_D13 GSE139377.ERG.aortic-endothelial-cell_D13 208 bp overlap

ChIP aortic-endothelial-cell_D14 GSE139377.ERG.aortic-endothelial-cell_D14 266 bp overlap

ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 216 bp overlap

ChIP aortic-endothelial-cell_D19 GSE139377.ERG.aortic-endothelial-cell_D19 159 bp overlap

ChIP aortic-endothelial-cell_D24 GSE139377.ERG.aortic-endothelial-cell_D24 264 bp overlap

ChIP aortic-endothelial-cell_D28 GSE139377.ERG.aortic-endothelial-cell_D28 199 bp overlap

ChIP aortic-endothelial-cell_D33 GSE139377.ERG.aortic-endothelial-cell_D33 209 bp overlap

ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 277 bp overlap

ChIP aortic-endothelial-cell_D4 GSE139377.ERG.aortic-endothelial-cell_D4 188 bp overlap

ChIP aortic-endothelial-cell_D40 GSE139377.ERG.aortic-endothelial-cell_D40 256 bp overlap

ChIP aortic-endothelial-cell_D47 GSE139377.ERG.aortic-endothelial-cell_D47 190 bp overlap

ChIP aortic-endothelial-cell_D49 GSE139377.ERG.aortic-endothelial-cell_D49 230 bp overlap

ChIP aortic-endothelial-cell_D5 GSE139377.ERG.aortic-endothelial-cell_D5 227 bp overlap

ChIP aortic-endothelial-cell_D51 GSE139377.ERG.aortic-endothelial-cell_D51 239 bp overlap

ChIP aortic-endothelial-cell_D53 GSE139377.ERG.aortic-endothelial-cell_D53 163 bp overlap

ChIP arterial-endothelial-cells GSE128382.ERG.arterial-endothelial-cells 170 bp overlap

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 152 bp overlap

ETS1 6 datasets

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 309 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 278 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 309 bp overlap

ChIP HUVEC-C_VEGF_1H GSE41166.ETS1.HUVEC-C_VEGF_1H 173 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 278 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 258 bp overlap

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 193 bp overlap

FOXP2 1 dataset

ChIP PFSK1 ENCSR000BGA.FOXP2.PFSK1 137 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 181 bp overlap

GATA1 5 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 56 bp overlap

ChIP K-562 ENCSR000EWM.GATA1.K-562 159 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 183 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 196 bp overlap

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 133 bp overlap

GATA2 9 datasets

ChIP HUVEC-C GSE109625.GATA2.HUVEC-C 215 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.GATA2.HUVEC-C_VEGF_1h 197 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 187 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 183 bp overlap

ChIP endothelial cell of umbilical vein ENCFF148NLK 221 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EVW.GATA2.endothelial_umbilical-vein 389 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 284 bp overlap

ChIP hiPSC_SLC9ebs GSE107639.GATA2.hiPSC_SLC9ebs 347 bp overlap

GATA3 1 dataset

ChIP MCF-7 ENCFF352QVM 427 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 228 bp overlap

GATA6 6 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 368 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 387 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 522 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 302 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 485 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 522 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 320 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 365 bp overlap

GMEB1 1 dataset

ChIP K-562 ENCSR928KOR.GMEB1.K-562 224 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR711VWL.HDAC1.K-562 268 bp overlap

ChIP K-562 ENCSR387UWP.HDAC1.K-562 376 bp overlap

ChIP K562 ENCFF968WBH 458 bp overlap

HDAC2 3 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 395 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 368 bp overlap

ChIP K562 ENCFF744ALD 408 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 306 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 180 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 161 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 345 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 232 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 401 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 304 bp overlap

ChIP K-562 ENCSR000EGN.JUND.K-562 117 bp overlap

KDM1A 7 datasets

ChIP K-562 ENCSR908CMW.KDM1A.K-562 369 bp overlap

ChIP K-562 GSE117944.KDM1A.K-562 336 bp overlap

ChIP K-562 ENCSR360HRA.KDM1A.K-562 344 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 250 bp overlap

ChIP K562 ENCFF128TYE 397 bp overlap

ChIP K562 ENCFF133OLU 461 bp overlap

ChIP K562 ENCFF934ZRG 449 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 181 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 509 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 382 bp overlap

KLF17 3 datasets

ChIP HEK293 ENCFF658MHR 383 bp overlap

ChIP HEK293 ENCFF658MHR 365 bp overlap

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 425 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 295 bp overlap

ChIP keratinocyte_diff GSE57702.KLF4.keratinocyte_diff 227 bp overlap

KMT2D 1 dataset

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.KMT2D.BIN-67_lentivirus-SMARCA4 407 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 135 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 231 bp overlap

ChIP K562 ENCFF333ZIV 328 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 95 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 140 bp overlap

ChIP K-562 ENCSR807BGP.MTA1.K-562 200 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 403 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DLU.MYC.endothelial_umbilical-vein 240 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DLU.MYC.endothelial_umbilical-vein 113 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 137 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 209 bp overlap

NR2F2 2 datasets

ChIP liver ENCFF565JGD 304 bp overlap

ChIP liver ENCSR168SMX.NR2F2.liver 274 bp overlap

ChIP K562 ENCFF689EWI 153 bp overlap

ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 164 bp overlap

POLR2A 6 datasets

ChIP PFSK-1 ENCFF576NIT 177 bp overlap

ChIP endothelial cell of umbilical vein ENCFF131DWO 201 bp overlap

ChIP endothelial cell of umbilical vein ENCFF303XUJ 116 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 348 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 376 bp overlap

ChIP stomach ENCFF607ZPU 325 bp overlap

POU5F1 3 datasets

ChIP BG03 GSE21614.POU5F1.BG03 139 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 522 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 343 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 416 bp overlap

PPARG 2 datasets

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 176 bp overlap

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 61 bp overlap

RAD21 3 datasets

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 293 bp overlap

ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 198 bp overlap

ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 200 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

RELA 9 datasets

ChIP HAEC GSE89970.RELA.HAEC 134 bp overlap

ChIP HUVEC-C_TNF-30min GSE121890.RELA.HUVEC-C_TNF-30min 203 bp overlap

ChIP HUVEC-C_TNF_30M GSE34500.RELA.HUVEC-C_TNF_30M 196 bp overlap

ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 238 bp overlap

ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 174 bp overlap

ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 239 bp overlap

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 165 bp overlap

ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 224 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 191 bp overlap

SIN3A 1 dataset

ChIP PFSK-1 ENCFF218MAY 274 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 402 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 522 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 522 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 409 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 520 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 522 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 509 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 427 bp overlap

SMARCA4 1 dataset

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 333 bp overlap

SMARCC1 1 dataset

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4 263 bp overlap

ChIP HCAEC GSE101921.SMC1.HCAEC 522 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 170 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 293 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 291 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 384 bp overlap

ChIP K562 ENCFF059YCJ 378 bp overlap

ChIP Hep-G2 ENCSR460YAM.SP1.Hep-G2 127 bp overlap

ChIP liver ENCFF769YSM 346 bp overlap

ChIP liver ENCFF769YSM 484 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 163 bp overlap

SPI1 5 datasets

ChIP K-562 GSE70482.SPI1.K-562 288 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 175 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 155 bp overlap

ChIP K-562_SAHA GSE74999.SPI1.K-562_SAHA 126 bp overlap

ChIP K562 ENCFF410ORC 205 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SS18.BIN-67_lentivirus-SMARCA4 186 bp overlap

STAT1 1 dataset

ChIP SET-2_DMSO GSE100566.STAT1.SET-2_DMSO 155 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 241 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 197 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 284 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 313 bp overlap

ChIP PFSK-1 ENCFF982LZL 411 bp overlap

ChIP K-562 GSE55306.TBP.K-562 176 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 135 bp overlap

TCF12 1 dataset

ChIP Kasumi-1 GSE23730.TCF12.Kasumi-1 178 bp overlap

VEZF1 2 datasets

ChIP K-562 ENCSR189YMA.VEZF1.K-562 221 bp overlap

ChIP K562 ENCFF053XDV 455 bp overlap

XRCC5 2 datasets

ChIP K-562 GSE120104.XRCC5.K-562 280 bp overlap

ChIP K-562 ENCSR506KWJ.XRCC5.K-562 176 bp overlap

ZBTB2 1 dataset

ChIP GM12878 GSE97661.ZBTB2.GM12878 124 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 220 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 253 bp overlap

ZFP36 2 datasets

ChIP K-562 ENCSR776CYN.ZFP36.K-562 182 bp overlap

ChIP K562 ENCFF255RZG 297 bp overlap

ZNF18 2 datasets

ChIP HEK293 ENCFF066NGR 303 bp overlap

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 245 bp overlap

ZNF257 2 datasets

ChIP HEK293T GSE78099.ZNF257.HEK293T 86 bp overlap

ChIP K-562 ENCSR492FKD.ZNF257.K-562 191 bp overlap

ZNF398 2 datasets

ChIP HEK293 ENCFF184XEW 116 bp overlap

ChIP HEK293 ENCSR676ZEF.ZNF398.HEK293 267 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 150 bp overlap

ZNF410 1 dataset

ChIP K-562 GSE97661.ZNF410.K-562 144 bp overlap

ZNF444 2 datasets

ChIP MCF-7 ENCFF602QFR 345 bp overlap

ChIP MCF-7 ENCSR038XIA.ZNF444.MCF-7 216 bp overlap

ZNF865 1 dataset

ChIP HepG2 ENCFF472KAQ 120 bp overlap

ZSCAN4 2 datasets

ChIP HEK293 ENCFF381BKT 316 bp overlap

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 386 bp overlap