chr1 : 225,951,130 – 225,951,299
169 bp 116 TFs 1 linked gene
This 169 bp open chromatin element is linked to LEFTY2 and is bound by 116 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LEFTY2 9.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:225,946,130 – 225,956,299
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
116 transcription factors
Source
Cell type
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 169 bp overlap
BCL11A 1 dataset
ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 84 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 129 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 169 bp overlap
BRD2 4 datasets
ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 169 bp overlap
ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 169 bp overlap
ChIP THP-1_iBET-BD1 GSE138084.BRD2.THP-1_iBET-BD1 169 bp overlap
ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 169 bp overlap
BRD3 1 dataset
ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 169 bp overlap
BRD4 3 datasets
ChIP THP-1_DMSO GSE138084.BRD4.THP-1_DMSO 169 bp overlap
ChIP THP-1_DMSO-PMA GSE138084.BRD4.THP-1_DMSO-PMA 155 bp overlap
ChIP hESC GSE33281.BRD4.hESC 135 bp overlap
CBFB 1 dataset
ChIP ME-1 GSE46044.CBFB.ME-1 169 bp overlap
CBX2 1 dataset
ChIP HEK293T GSE34774.CBX2.HEK293T 169 bp overlap
CTBP2 1 dataset
ChIP WA01 ENCSR000EUO.CTBP2.WA01 113 bp overlap
CTCF 35 datasets
ChIP 22Rv1 ENCFF466OXN 169 bp overlap
ChIP 22Rv1 ENCFF466OXN 169 bp overlap
ChIP 22Rv1 ENCSR857PBV.CTCF.22Rv1 169 bp overlap
ChIP 22Rv1_hydroxy_10nM_4h ENCSR847XGE.CTCF.22Rv1_hydroxy_10nM_4h 169 bp overlap
ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 169 bp overlap
ChIP BE2C ENCFF757SRF 169 bp overlap
ChIP BE2C ENCSR000DQD.CTCF.BE2C 168 bp overlap
ChIP CD14-positive monocyte ENCFF087XLR 169 bp overlap
ChIP GM04604 GSE148179.CTCF.GM04604 147 bp overlap
ChIP GM04648 GSE148179.CTCF.GM04648 169 bp overlap
ChIP Hep-G2 ENCSR000DUG.CTCF.Hep-G2 116 bp overlap
ChIP HepG2 ENCFF127KUP 169 bp overlap
ChIP K-562 ENCSR000DWE.CTCF.K-562 169 bp overlap
ChIP K-562 GSE70482.CTCF.K-562 161 bp overlap
ChIP K-562_13189 GSE131349.CTCF.K-562_13189 102 bp overlap
ChIP K-562_14259 GSE131349.CTCF.K-562_14259 102 bp overlap
ChIP K-562_15776 GSE131349.CTCF.K-562_15776 129 bp overlap
ChIP K-562_7140 GSE131349.CTCF.K-562_7140 114 bp overlap
ChIP K562 ENCFF082GOI 138 bp overlap
ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 157 bp overlap
ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-000m 152 bp overlap
ChIP THP-1_Pam3csk-000m-Flavo-240m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-240m 165 bp overlap
ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-020m-Flavo-000m 169 bp overlap
ChIP THP-1_Pam3csk-025m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-025m-Flavo-000m 155 bp overlap
ChIP THP-1_Pam3csk-045m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-045m-Flavo-000m 169 bp overlap
ChIP THP-1_Pam3csk-360m-Flavo-240m GSE103477.CTCF.THP-1_Pam3csk-360m-Flavo-240m 131 bp overlap
ChIP THP-1_macrophage_PMA GSE96800.CTCF.THP-1_macrophage_PMA 169 bp overlap
ChIP THP-1_siCtrl-eGFP-Pam3csk-4h GSE103477.CTCF.THP-1_siCtrl-eGFP-Pam3csk-4h 163 bp overlap
ChIP aorta_thoracic ENCSR668BTN.CTCF.aorta_thoracic 169 bp overlap
ChIP erythroblast_adult_erythroblasts GSE102184.CTCF.erythroblast_adult_erythroblasts 169 bp overlap
ChIP fetal_erythroblasts GSE102184.CTCF.fetal_erythroblasts 162 bp overlap
ChIP leukemia GSE142161.CTCF.leukemia 169 bp overlap
ChIP leukemia_CEBPA-168h GSE142161.CTCF.leukemia_CEBPA-168h 155 bp overlap
ChIP leukemia_CEBPA-24h GSE142161.CTCF.leukemia_CEBPA-24h 153 bp overlap
ChIP leukemia_CEBPA-96h GSE142161.CTCF.leukemia_CEBPA-96h 161 bp overlap
CTCFL 1 dataset
Motif DE_12h DE_12h-CTCFL_MA1102.3 8 bp overlap
CTCF_s 1 dataset
ChIP HeLa-S3_biotin GSE108869.CTCF_s.HeLa-S3_biotin 169 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF274GAT 94 bp overlap
ChIP BLaER1 ENCFF364PUR 134 bp overlap
EGR1 1 dataset
ChIP H1 ENCFF451BLH 164 bp overlap
ERG 3 datasets
ChIP ME-1 GSE46044.ERG.ME-1 169 bp overlap
ChIP SKNO-1 GSE23730.ERG.SKNO-1 165 bp overlap
ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 169 bp overlap
ESR1 5 datasets
ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 162 bp overlap
ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 169 bp overlap
ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 110 bp overlap
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 169 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 115 bp overlap
EWSR1-FLI1 1 dataset
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH1 1 dataset
ChIP ProEs_SHCTR GSE59087.EZH1.ProEs_SHCTR 59 bp overlap
FLI1 1 dataset
ChIP SKNO-1 GSE23730.FLI1.SKNO-1 156 bp overlap
GATA2 2 datasets
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 145 bp overlap
ChIP SKH1 GSE87283.GATA2.SKH1 59 bp overlap
GATAD2A 1 dataset
ChIP K562 ENCFF071LJW 87 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 169 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 167 bp overlap
GLIS2 2 datasets
ChIP HEK293 ENCFF446EIF 169 bp overlap
ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 115 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 169 bp overlap
HDAC2 1 dataset
ChIP PC-3 GSE147455.HDAC2.PC-3 115 bp overlap
HDGF 1 dataset
ChIP HEK293T ENCFF357ANX 84 bp overlap
HMGXB4 1 dataset
ChIP Hep-G2 ENCSR174GOO.HMGXB4.Hep-G2 142 bp overlap
HNRNPLL 1 dataset
ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 75 bp overlap
IKZF1 4 datasets
ChIP BCR-ABL1_LAX2 GSE58825.IKZF1.BCR-ABL1_LAX2 150 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 138 bp overlap
ChIP K562 ENCFF348IBL 169 bp overlap
ChIP K562 ENCFF771OHZ 51 bp overlap
ILF3 1 dataset
ChIP K-562 GSE103215.ILF3.K-562 169 bp overlap
JMJD1C 1 dataset
ChIP THP-1 GSE63484.JMJD1C.THP-1 169 bp overlap
JUN 1 dataset
ChIP MDA-BoM-1833_shp27 GSE112444.JUN.MDA-BoM-1833_shp27 108 bp overlap
JUND 1 dataset
ChIP K-562 ENCSR000EGN.JUND.K-562 139 bp overlap
KAT7 1 dataset
ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 169 bp overlap
KDM6B 1 dataset
ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 154 bp overlap
KLF5 1 dataset
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
KMT2A 2 datasets
ChIP MV4-11 GSE79899.KMT2A.MV4-11 169 bp overlap
ChIP THP-1 GSE79899.KMT2A.THP-1 169 bp overlap
KMT2B 2 datasets
ChIP AML GSE112074.KMT2B.AML 169 bp overlap
ChIP AML_OG86 GSE112074.KMT2B.AML_OG86 169 bp overlap
MAX 1 dataset
ChIP K-562 ENCSR000EFV.MAX.K-562 111 bp overlap
MAZ 1 dataset
ChIP K-562 ENCSR000EFX.MAZ.K-562 136 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 55 bp overlap
MTA3 2 datasets
ChIP K-562 ENCSR180NCY.MTA3.K-562 169 bp overlap
ChIP K-562 ENCSR914NEI.MTA3.K-562 169 bp overlap
MYB 1 dataset
ChIP THP-1 GSE90769.MYB.THP-1 78 bp overlap
NELFE 2 datasets
ChIP K-562_HS GSE112379.NELFE.K-562_HS 161 bp overlap
ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 123 bp overlap
NFKB1 1 dataset
ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 152 bp overlap
NONO 1 dataset
ChIP K-562 ENCSR010KFT.NONO.K-562 153 bp overlap
NR4A1 1 dataset
ChIP Kasumi-1 GSE79491.NR4A1.Kasumi-1 57 bp overlap
PATZ1 1 dataset
ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 169 bp overlap
PLAG1 1 dataset
Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap
POU5F1 2 datasets
ChIP BG03 GSE21614.POU5F1.BG03 169 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 169 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 169 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 169 bp overlap
Pparg::Rxra 1 dataset
Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap
RAD21 1 dataset
ChIP THP-1_eGFP-IFNb GSE103477.RAD21.THP-1_eGFP-IFNb 169 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 131 bp overlap
RBFOX2 2 datasets
ChIP K-562 ENCSR822LBD.RBFOX2.K-562 128 bp overlap
ChIP K-562 GSE120104.RBFOX2.K-562 121 bp overlap
RELA 1 dataset
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 148 bp overlap
REST 1 dataset
ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 136 bp overlap
RNF2 1 dataset
ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 168 bp overlap
RUNX1 1 dataset
ChIP THP-1 GSE79899.RUNX1.THP-1 169 bp overlap
SCRT1 2 datasets
ChIP HEK293 ENCFF513YVP 169 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 169 bp overlap
SCRT2 1 dataset
ChIP HEK293 ENCFF711QQB 169 bp overlap
SIN3A 3 datasets
ChIP K-562 ENCSR920BLG.SIN3A.K-562 87 bp overlap
ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 155 bp overlap
ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 152 bp overlap
SMAD2 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 169 bp overlap
SMAD2-3 2 datasets
ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 126 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 169 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 169 bp overlap
SMAD3 2 datasets
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 151 bp overlap
ChIP hESC GSE29422.SMAD3.hESC 169 bp overlap
SMARCA4 2 datasets
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 162 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 169 bp overlap
SMC3 1 dataset
ChIP K-562 ENCSR000EGW.SMC3.K-562 112 bp overlap
SP1 4 datasets
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
ChIP HEK293 GSE76494.SP1.HEK293 169 bp overlap
ChIP Hep-G2 ENCSR460YAM.SP1.Hep-G2 140 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 140 bp overlap
SP4 2 datasets
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
ChIP HEK293 GSE76494.SP4.HEK293 169 bp overlap
SP5 2 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
ChIP Hep-G2 ENCSR019NPF.SP5.Hep-G2 119 bp overlap
SPI1 14 datasets
ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 130 bp overlap
ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 150 bp overlap
ChIP HL-60 ENCFF645GBT 95 bp overlap
ChIP K-562 GSE70482.SPI1.K-562 109 bp overlap
ChIP K-562 ENCSR000BGW.SPI1.K-562 85 bp overlap
ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 109 bp overlap
ChIP K562 ENCFF410ORC 126 bp overlap
ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 169 bp overlap
ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 135 bp overlap
ChIP THP-1_DIFF GSE25426.SPI1.THP-1_DIFF 90 bp overlap
ChIP monocyte GSE31621.SPI1.monocyte 81 bp overlap
ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 127 bp overlap
ChIP primary-monocyte_donorA_ncMO GSE128834.SPI1.primary-monocyte_donorA_ncMO 145 bp overlap
ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 57 bp overlap
SREBP2 1 dataset
ChIP monocyte GSE129202.SREBP2.monocyte 169 bp overlap
SUPT5H 1 dataset
ChIP HEK293_PNUTS GSE134198.SUPT5H.HEK293_PNUTS 62 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 169 bp overlap
TBP 1 dataset
ChIP K-562 GSE55306.TBP.K-562 169 bp overlap
TP53 1 dataset
ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 169 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 169 bp overlap
VDR 1 dataset
ChIP THP-1_1d_1-25-OH-2D3 GSE89431.VDR.THP-1_1d_1-25-OH-2D3 169 bp overlap
XRCC5 1 dataset
ChIP K-562 GSE120104.XRCC5.K-562 158 bp overlap
YY1 3 datasets
ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 169 bp overlap
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 169 bp overlap
ChIP WA01 ENCSR000BKD.YY1.WA01 123 bp overlap
ZBTB17 1 dataset
ChIP HEK293 ENCFF865LIO 169 bp overlap
ZBTB44 2 datasets
ChIP HEK293 ENCFF560VPN 125 bp overlap
ChIP HEK293 ENCSR076STQ.ZBTB44.HEK293 95 bp overlap
ZBTB7A 3 datasets
ChIP K-562 GSE103445.ZBTB7A.K-562 153 bp overlap
ChIP K-562 ENCSR000BME.ZBTB7A.K-562 142 bp overlap
ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 133 bp overlap
ZFP91 2 datasets
ChIP HepG2 ENCFF012CME 169 bp overlap
ChIP HepG2 ENCFF012CME 169 bp overlap
ZIC1 1 dataset
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
ZIC2 1 dataset
ChIP HCT-116_WT GSE127960.ZIC2.HCT-116_WT 169 bp overlap
ZIC4 1 dataset
Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap
ZIC5 7 datasets
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
ChIP HCT-116_C16-CT289 GSE127960.ZIC5.HCT-116_C16-CT289 169 bp overlap
ChIP HCT-116_C18-CT289 GSE127960.ZIC5.HCT-116_C18-CT289 169 bp overlap
ChIP HCT-116_WT-CT289 GSE127960.ZIC5.HCT-116_WT-CT289 169 bp overlap
ChIP HCT-116_WT-FL290 GSE127960.ZIC5.HCT-116_WT-FL290 169 bp overlap
ChIP HCT-116_sc1 GSE127960.ZIC5.HCT-116_sc1 169 bp overlap
ChIP HCT-116_sc2 GSE127960.ZIC5.HCT-116_sc2 169 bp overlap
ZKSCAN1 1 dataset
ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 153 bp overlap
ZNF121 1 dataset
ChIP WTC11 ENCFF291API 169 bp overlap
ZNF143 1 dataset
ChIP WA01 ENCSR000EBW.ZNF143.WA01 137 bp overlap
ZNF148 1 dataset
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
ZNF205 1 dataset
ChIP HepG2 ENCFF931LZG 169 bp overlap
ZNF257 1 dataset
ChIP HEK293T GSE78099.ZNF257.HEK293T 120 bp overlap
ZNF263 2 datasets
Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap
ChIP K-562 ENCSR000EWN.ZNF263.K-562 86 bp overlap
ZNF273 1 dataset
ChIP HEK293T GSE78099.ZNF273.HEK293T 135 bp overlap
ZNF276 1 dataset
ChIP Hep-G2 ENCSR076KLJ.ZNF276.Hep-G2 96 bp overlap
ZNF281 2 datasets
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
ZNF300 1 dataset
ChIP HEK293T GSE78099.ZNF300.HEK293T 155 bp overlap
ZNF320 1 dataset
Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap
ZNF322 1 dataset
ChIP HEK293 GSE76494.ZNF322.HEK293 136 bp overlap
ZNF341 3 datasets
ChIP HEK293 ENCFF944VMC 169 bp overlap
ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 163 bp overlap
ChIP HEK293 GSE76494.ZNF341.HEK293 145 bp overlap
ZNF479 1 dataset
ChIP HEK293T GSE78099.ZNF479.HEK293T 86 bp overlap
ZNF506 1 dataset
ChIP HEK293T GSE78099.ZNF506.HEK293T 120 bp overlap
ZNF554 1 dataset
ChIP HEK293 GSE76494.ZNF554.HEK293 169 bp overlap
ZNF558 1 dataset
ChIP HEK293T GSE78099.ZNF558.HEK293T 169 bp overlap
ZNF592 1 dataset
ChIP K562 ENCFF547OSS 169 bp overlap
ZNF701 1 dataset
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
ZNF711 1 dataset
ChIP HEK293T GSE145160.ZNF711.HEK293T 169 bp overlap
ZNF816 1 dataset
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
Zic1::Zic2 1 dataset
Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap
Zic2 1 dataset
Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap
Zic3 1 dataset
Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap
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