chr10:122,877,140–122,877,717

chr10 : 122,877,140 – 122,877,717

577 bp 112 TFs 10 linked genes

This 577 bp open chromatin element is linked to 10 target genes and is bound by 112 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000286088		1.9 kb	Proximal	Proximity
FAM24B		1.9 kb	Proximal	Proximity
ENSG00000293310		2.0 kb	Proximal	Proximity
C10orf88B		2.1 kb	Proximal	Proximity
CUZD1		31.7 kb	Distal	Multiome
C10orf88		76.7 kb	Distal	Multiome
PSTK		102.9 kb	Distal	Multiome
IKZF5		131.1 kb	Distal	Multiome
ACADSB		131.5 kb	Distal	Multiome
BUB3		276.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

112 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 521 bp overlap

ChIP K562 ENCFF938UXQ 424 bp overlap

ARID3A 1 dataset

ChIP K-562 ENCSR000EFY.ARID3A.K-562 199 bp overlap

ATF3 4 datasets

ChIP K-562 ENCSR028UIU.ATF3.K-562 427 bp overlap

ChIP K-562 ENCSR632DCH.ATF3.K-562 368 bp overlap

ChIP K562 ENCFF604FPV 211 bp overlap

ChIP K562 ENCFF921JQW 577 bp overlap

ChIP HUDEP-2 GSE143961.ATF4.HUDEP-2 190 bp overlap

Motif DE_36h DE_36h-Atf3_MA1988.2 7 bp overlap

BACH1 1 dataset

Motif DE_36h DE_36h-BACH1_MA1633.2 9 bp overlap

Motif DE_36h DE_36h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_36h DE_36h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_36h DE_36h-BATFJUN_MA0462.3 7 bp overlap

BCL11A 3 datasets

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 93 bp overlap

ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 72 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 117 bp overlap

Motif DE_36h DE_36h-BNC2_MA1928.2 7 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 334 bp overlap

ChIP K562 ENCFF963TXY 215 bp overlap

CBFA2T3 3 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 478 bp overlap

ChIP K-562 GSE142227.CBFA2T3.K-562 212 bp overlap

ChIP K562 ENCFF673OEZ 373 bp overlap

CCNT2 2 datasets

ChIP K-562 ENCSR000DOA.CCNT2.K-562 231 bp overlap

ChIP K562 ENCFF199GSZ 378 bp overlap

CEBPB 2 datasets

ChIP K-562 ENCSR000EHE.CEBPB.K-562 157 bp overlap

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 115 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 253 bp overlap

ChIP K-562 ENCSR077DKV.CREM.K-562 225 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 339 bp overlap

DPF2 2 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 407 bp overlap

ChIP K562 ENCFF775HUO 372 bp overlap

ChIP K562 ENCFF688PUB 564 bp overlap

EGR1 4 datasets

ChIP K-562 ENCSR024CNP.EGR1.K-562 219 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 135 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP K562 ENCFF895KGN 385 bp overlap

Motif DE_36h DE_36h-ELF4_MA0641.1 12 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 274 bp overlap

EP300 2 datasets

ChIP K-562 ENCSR000EGE.EP300.K-562 307 bp overlap

ChIP K562 ENCFF226VMS 317 bp overlap

Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap

Motif DE_36h DE_36h-FOS_MA0476.2 8 bp overlap

ChIP K-562 ENCSR000DKB.FOS.K-562 114 bp overlap

FOS::JUND 1 dataset

Motif DE_36h DE_36h-FOSJUND_MA1141.2 9 bp overlap

FOSL1 3 datasets

Motif DE_36h DE_36h-FOSL1_MA0477.3 9 bp overlap

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 374 bp overlap

ChIP K-562 ENCSR000BMV.FOSL1.K-562 140 bp overlap

FOSL1::JUN 1 dataset

Motif DE_36h DE_36h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUND 1 dataset

Motif DE_36h DE_36h-FOSL1JUND_MA1142.2 8 bp overlap

FOSL2::JUN 1 dataset

Motif DE_36h DE_36h-FOSL2JUN_MA1130.2 9 bp overlap

GATA1 16 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 111 bp overlap

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 71 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 360 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 254 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 105 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 61 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 469 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 190 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 246 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 330 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

ChIP erythroblast ENCFF867JAR 456 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 532 bp overlap

ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 501 bp overlap

ChIP erythroid_Don002 GSE137982.GATA1.erythroid_Don002 307 bp overlap

ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 324 bp overlap

GATA1::TAL1 1 dataset

Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 8 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 384 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 524 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 267 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 226 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 233 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 551 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 394 bp overlap

ChIP DE DE-GATA4-2 376 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 384 bp overlap

ChIP DE DE-GATA6-2 406 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 465 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 481 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 543 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 577 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 470 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 414 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 359 bp overlap

ChIP K562 ENCFF968WBH 453 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 269 bp overlap

ChIP K562 ENCFF744ALD 421 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 156 bp overlap

ChIP K562 ENCFF055GAZ 531 bp overlap

ChIP K562 ENCFF317JJX 521 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 529 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 381 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 571 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 463 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 503 bp overlap

ChIP K-562 ENCSR000FAH.JUN.K-562 122 bp overlap

JUN::JUNB 1 dataset

Motif DE_36h DE_36h-JUNJUNB_MA1132.2 8 bp overlap

ChIP K-562 ENCSR000DJY.JUNB.K-562 138 bp overlap

JUND 3 datasets

ChIP K-562 ENCSR000EGN.JUND.K-562 215 bp overlap

ChIP K562 ENCFF336RCR 461 bp overlap

ChIP K562 ENCFF830LVJ 281 bp overlap

Motif DE_36h DE_36h-Jun_MA0489.3 8 bp overlap

KLF1 3 datasets

Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap

ChIP HUDEP-2_S2 GSE97671.KLF1.HUDEP-2_S2 154 bp overlap

ChIP erythroid_R3R4 GSE43625.KLF1.erythroid_R3R4 70 bp overlap

KLF10 1 dataset

Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap

KLF14 1 dataset

Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap

KLF16 2 datasets

ChIP K-562 ENCSR760UVO.KLF16.K-562 313 bp overlap

ChIP K562 ENCFF464PIV 345 bp overlap

Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap

Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap

Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap

Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 199 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 261 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 431 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 183 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 123 bp overlap

MEIS1 1 dataset

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

MEIS2 2 datasets

ChIP K-562 ENCSR851BNE.MEIS2.K-562 228 bp overlap

ChIP K562 ENCFF320GSD 353 bp overlap

MTA2 2 datasets

ChIP K-562 ENCSR113LAS.MTA2.K-562 395 bp overlap

ChIP K562 ENCFF880VZB 341 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 310 bp overlap

NCOR1 4 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 365 bp overlap

ChIP K-562 ENCSR910JAI.NCOR1.K-562 204 bp overlap

ChIP K562 ENCFF788MPU 187 bp overlap

ChIP K562 ENCFF866HRM 264 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 180 bp overlap

NFIC 2 datasets

ChIP K-562 ENCSR796ITY.NFIC.K-562 190 bp overlap

ChIP K562 ENCFF167YID 387 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 191 bp overlap

NFKB2 1 dataset

ChIP L1236 GSE63736.NFKB2.L1236 206 bp overlap

NR2F1 1 dataset

ChIP K562 ENCFF221HJH 443 bp overlap

NR2F2 2 datasets

ChIP K-562 ENCSR000BRS.NR2F2.K-562 291 bp overlap

ChIP K562 ENCFF004YPK 391 bp overlap

NR2F6 2 datasets

ChIP K-562 ENCSR707QWA.NR2F6.K-562 467 bp overlap

ChIP K562 ENCFF674RQA 457 bp overlap

NR4A1 1 dataset

Motif DE_36h DE_36h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_36h DE_36h-NR4A2_MA0160.3 8 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 141 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 239 bp overlap

ChIP K562 ENCFF801LKH 450 bp overlap

POLR2A 1 dataset

ChIP K562 ENCFF514URW 405 bp overlap

POU2F3 1 dataset

Motif DE_36h DE_36h-POU2F3_MA0627.3 9 bp overlap

POU5F1 4 datasets

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 202 bp overlap

Motif DE_36h DE_36h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 357 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 337 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP L1236 GSE63736.RELB.L1236 139 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 144 bp overlap

ChIP K562 ENCFF653BQJ 523 bp overlap

RUNX1 2 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 328 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 328 bp overlap

Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap

SMAD1 1 dataset

ChIP CD34_ERYTH_BMP GSE29194.SMAD1.CD34_ERYTH_BMP 149 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 467 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 552 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 466 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 569 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 554 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 534 bp overlap

SMAD4 1 dataset

ChIP K562 ENCFF628RBP 437 bp overlap

SMARCA4 4 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 545 bp overlap

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 293 bp overlap

ChIP K562 ENCFF506JCB 262 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 235 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 257 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 163 bp overlap

SMARCE1 2 datasets

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 455 bp overlap

ChIP K562 ENCFF690CFF 501 bp overlap

SNAI2 2 datasets

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 203 bp overlap

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 170 bp overlap

SOX15 1 dataset

Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 293 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 422 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 181 bp overlap

SOX21 1 dataset

Motif DE_36h DE_36h-SOX21_MA0866.1 15 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 307 bp overlap

ChIP K562 ENCFF059YCJ 152 bp overlap

SPI1 4 datasets

ChIP K-562 ENCSR000BGW.SPI1.K-562 196 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 128 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 196 bp overlap

ChIP K-562_SAHA GSE74999.SPI1.K-562_SAHA 142 bp overlap

Motif DE_36h DE_36h-Sox1_MA0870.1 15 bp overlap

TAL1 14 datasets

ChIP CD34 GSE52924.TAL1.CD34 277 bp overlap

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 214 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 376 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 327 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 340 bp overlap

ChIP K-562_MYO1D-Non-hub_KO GSE107726.TAL1.K-562_MYO1D-Non-hub_KO 233 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 245 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 167 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 298 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 286 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 244 bp overlap

ChIP K562 ENCFF620GMX 273 bp overlap

ChIP K562 ENCFF661CCK 121 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 318 bp overlap

TBX20 1 dataset

Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap

TCF12 4 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 279 bp overlap

ChIP K-562 ENCSR189TRZ.TCF12.K-562 213 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 251 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 337 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF465AQA 297 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 285 bp overlap

TRIM28 1 dataset

ChIP K562 ENCFF172UPN 390 bp overlap

VEZF1 1 dataset

ChIP K562 ENCFF053XDV 577 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 105 bp overlap

ZBTB7A 4 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 577 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 410 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 191 bp overlap

ChIP K562 ENCFF579ZGM 401 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 228 bp overlap

ZNF384 1 dataset

Motif DE_36h DE_36h-ZNF384_MA1125.2 8 bp overlap

ZNF449 1 dataset

Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap

ZNF680 2 datasets

ChIP HEK293 ENCFF418WHE 164 bp overlap

ChIP HEK293 ENCSR307CKC.ZNF680.HEK293 160 bp overlap