Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for FAM24B. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = FAM24B upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of FAM24B, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr10:122,683,538–122,684,537 | 195.7 kb | Distal (>10kb) Multiome | 21 | |
| chr10:122,875,885–122,876,836 | 3.3 kb | Proximal (<10kb) Multiome | 128 | |
| chr10:122,877,140–122,877,717 | 2.1 kb | Proximal (<10kb) Multiome | 112 | |
| chr10:122,878,115–122,878,545 | 1.1 kb | Proximal (<10kb) | 11 | |
| chr10:122,879,124–122,880,264 | 126 bp | At TSS Multiome | 712 | |
| chr10:122,953,726–122,954,686 | 74.6 kb | Distal (>10kb) Multiome | 995 | |
| chr10:122,980,093–122,981,015 | 100.9 kb | Distal (>10kb) Multiome | 874 | |
| chr10:123,007,898–123,009,768 | 129.3 kb | Distal (>10kb) Multiome | 911 | |
| chr10:123,132,736–123,133,704 | 253.5 kb | Distal (>10kb) Multiome | 384 | |
| chr10:123,135,104–123,137,885 | 257.6 kb | Distal (>10kb) Multiome | 563 | |
| chr10:123,139,520–123,140,375 | 260.4 kb | Distal (>10kb) Multiome | 456 | |
| chr10:123,147,570–123,148,872 | 268.4 kb | Distal (>10kb) Multiome | 310 | |
| chr10:123,150,788–123,151,726 | 271.6 kb | Distal (>10kb) Multiome | 224 | |
| chr10:123,153,975–123,155,184 | 274.6 kb | Distal (>10kb) Multiome | 787 |
Genomic view of the FAM24B locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.