chr10:101,311,194–101,311,678

chr10 : 101,311,194 – 101,311,678

484 bp 94 TFs 6 linked genes

This 484 bp open chromatin element is linked to 6 target genes and is bound by 94 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000225208		176 bp	At TSS	Proximity
BTRC		42.9 kb	Distal	Multiome
ENSG00000273162		250.3 kb	Distal	Multiome
POLL		276.8 kb	Distal	Multiome
DPCD		277.0 kb	Distal	Multiome
PDZD7		280.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

94 transcription factors

ChIP K562 ENCFF492SKF 196 bp overlap

ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 56 bp overlap

ARID1A 2 datasets

ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 213 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 76 bp overlap

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 133 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 368 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 406 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 161 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 274 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 200 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 155 bp overlap

BRD4 9 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 484 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 63 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 138 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 484 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 459 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 464 bp overlap

ChIP hESC GSE33281.BRD4.hESC 93 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 253 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 223 bp overlap

CDKN1B 2 datasets

ChIP MDA-BoM-1833_shp27 GSE112444.CDKN1B.MDA-BoM-1833_shp27 144 bp overlap

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 190 bp overlap

CHD2 2 datasets

ChIP H1 ENCFF991MKH 211 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 129 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCFF432ZEW 173 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 171 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 89 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 239 bp overlap

CTCF 4 datasets

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 134 bp overlap

ChIP gastroesophageal-sphincter ENCSR146BGM.CTCF.gastroesophageal-sphincter 187 bp overlap

ChIP heart_left-ventricle ENCSR544APK.CTCF.heart_left-ventricle 208 bp overlap

ChIP islet ERP004003.CTCF.islet 235 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 291 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 208 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 338 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 122 bp overlap

EP300 4 datasets

ChIP H1 ENCFF927IYK 192 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 135 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 215 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 484 bp overlap

ESR1 3 datasets

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 211 bp overlap

ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 117 bp overlap

ChIP breast_tumor_Male_15 GSE104399.ESR1.breast_tumor_Male_15 108 bp overlap

EZH2 9 datasets

ChIP GM23248 ENCSR131FFJ.EZH2.GM23248 79 bp overlap

ChIP RCH-ACV GSE135024.EZH2.RCH-ACV 114 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 210 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 73 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 54 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 292 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 364 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 159 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 86 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 290 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 111 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 202 bp overlap

GATA6 3 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 89 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 100 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 65 bp overlap

GMEB1 1 dataset

ChIP K-562 ENCSR928KOR.GMEB1.K-562 71 bp overlap

HCFC1 1 dataset

ChIP GM12878 ENCSR514VAY.HCFC1.GM12878 116 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 305 bp overlap

HNF4A 1 dataset

ChIP HCT-116_TCF4_DOX GSE62890.HNF4A.HCT-116_TCF4_DOX 230 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 408 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 184 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 426 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 165 bp overlap

JUND 2 datasets

ChIP H1 ENCFF468JZD 173 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 100 bp overlap

KDM1A 3 datasets

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 110 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 236 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 86 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 144 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 263 bp overlap

ChIP PDAC GSE64557.KLF4.PDAC 283 bp overlap

ChIP PDAC GSE64557.KLF6.PDAC 484 bp overlap

ChIP islet ERP004003.MAFB.islet 277 bp overlap

ChIP H1 ENCFF914VQY 223 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP WTC11 ENCFF223QFY 411 bp overlap

ChIP WTC11 ENCFF223QFY 368 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 83 bp overlap

MIER1 1 dataset

ChIP K-562 ENCSR426MDV.MIER1.K-562 194 bp overlap

MLLT1 4 datasets

ChIP GM12878 ENCFF995GXC 270 bp overlap

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 283 bp overlap

ChIP K-562 ENCSR107GRP.MLLT1.K-562 226 bp overlap

ChIP K562 ENCFF074XRJ 217 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 484 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 142 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 219 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 245 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 126 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 93 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 57 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 67 bp overlap

ChIP islet ERP001456.PDX1.islet 128 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 97 bp overlap

POLR2A 2 datasets

ChIP GM23338 ENCFF450WCS 375 bp overlap

ChIP body of pancreas ENCFF675RCN 272 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 161 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 202 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 230 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 74 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 79 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 472 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 274 bp overlap

RAD21 3 datasets

ChIP hiPSC_parental-line GSE106870.RAD21.hiPSC_parental-line 81 bp overlap

ChIP neural ENCSR198ZYJ.RAD21.neural 367 bp overlap

ChIP neural cell ENCFF564MOT 411 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 217 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 484 bp overlap

REST 10 datasets

ChIP K-562 ENCSR137ZMQ.REST.K-562 176 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 94 bp overlap

ChIP K-562 ENCSR137ZMQ.REST.K-562 72 bp overlap

ChIP K-562 ENCSR000ATM.REST.K-562 67 bp overlap

ChIP K562 ENCFF758CZL 120 bp overlap

ChIP PANC-1 ENCSR000BUP.REST.PANC-1 198 bp overlap

ChIP PANC-1 ENCSR000BPK.REST.PANC-1 147 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 194 bp overlap

ChIP hiPSC_IB12 GSE106870.REST.hiPSC_IB12 94 bp overlap

ChIP neural ENCSR000BTV.REST.neural 250 bp overlap

ChIP H1 ENCFF605EGG 371 bp overlap

RNF2 2 datasets

ChIP WA09 GSE105028.RNF2.WA09 204 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 140 bp overlap

SALL2 1 dataset

ChIP HEK293 GSE145940.SALL2.HEK293 182 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 352 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 384 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 335 bp overlap

SMARCA4 3 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 192 bp overlap

ChIP MCF-7 GSE123284.SMARCA4.MCF-7 68 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 164 bp overlap

SMC1A 1 dataset

ChIP primary-epidermal-keratinocyte_diff_d3 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d3 233 bp overlap

SMC3 2 datasets

ChIP neural ENCSR404BPV.SMC3.neural 484 bp overlap

ChIP neural cell ENCFF795YGY 352 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 182 bp overlap

ChIP H1 ENCFF263FUH 221 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 170 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 214 bp overlap

ChIP H1 ENCFF036PEF 161 bp overlap

ChIP K-562 ENCSR000BLK.SRF.K-562 123 bp overlap

ChIP K562 ENCFF664RPC 167 bp overlap

ChIP WA01 ENCSR000BIV.SRF.WA01 160 bp overlap

STAT3 13 datasets

ChIP HCC70 GSE152203.STAT3.HCC70 207 bp overlap

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 146 bp overlap

ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 337 bp overlap

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 223 bp overlap

ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 135 bp overlap

ChIP MCF-7_jc5844 GSE126004.STAT3.MCF-7_jc5844 83 bp overlap

ChIP MCF-7_jc5848 GSE126004.STAT3.MCF-7_jc5848 143 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 248 bp overlap

ChIP T-47D_JC4755 GSE126004.STAT3.T-47D_JC4755 228 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 200 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 254 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 260 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 306 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 484 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 359 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 472 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 171 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 128 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 178 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 322 bp overlap

TBX21 2 datasets

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 142 bp overlap

ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 119 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 140 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 282 bp overlap

ChIP NPC GSE154479.TCF3.NPC 177 bp overlap

TEAD4 2 datasets

ChIP MCF-7_E2 GSE125594.TEAD4.MCF-7_E2 217 bp overlap

ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 270 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 185 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 387 bp overlap

ChIP SUIT-2 GSE115461.TP63.SUIT-2 188 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 172 bp overlap

TSHZ2 1 dataset

ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 68 bp overlap

U2AF1 1 dataset

ChIP Hep-G2 GSE120104.U2AF1.Hep-G2 104 bp overlap

ChIP H1 ENCFF524BTL 214 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 162 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 144 bp overlap

ZBTB17 2 datasets

ChIP HEK293 ENCFF865LIO 482 bp overlap

ChIP K562 ENCFF731UTU 242 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 190 bp overlap

ZNF135 1 dataset

Motif DE_24h DE_24h-ZNF135_MA1587.1 14 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 133 bp overlap

ZNF148 2 datasets

ChIP K-562 ENCSR018MSO.ZNF148.K-562 295 bp overlap

ChIP K562 ENCFF352SDL 404 bp overlap

ZNF217 1 dataset

ChIP MCF-7 ENCSR465XQW.ZNF217.MCF-7 152 bp overlap

ZNF281 3 datasets

ChIP K-562 GSE121133.ZNF281.K-562 220 bp overlap

ChIP K562 ENCFF594VNM 302 bp overlap

ChIP WTC11 ENCFF551GAV 226 bp overlap

ZNF322 1 dataset

ChIP HEK293 GSE76494.ZNF322.HEK293 118 bp overlap

ZNF341 2 datasets

ChIP HEK293 ENCFF944VMC 65 bp overlap

ChIP HEK293 ENCFF944VMC 266 bp overlap

ZNF444 1 dataset

ChIP MCF-7 ENCSR038XIA.ZNF444.MCF-7 60 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 204 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 88 bp overlap