chr6:111,251,962–111,252,726

chr6 : 111,251,962 – 111,252,726

764 bp 110 TFs 7 linked genes

This 764 bp open chromatin element is linked to 7 target genes and is bound by 110 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MFSD4B-DT		6.3 kb	Proximal	Proximity
MFSD4B		6.6 kb	Proximal	Proximity
SLC16A10		164.7 kb	Distal	Multiome
TRAF3IP2-AS1		231.3 kb	Distal	Multiome
REV3L		231.5 kb	Distal	Multiome
RPF2		270.2 kb	Distal	Multiome
GTF3C6		293.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

110 transcription factors

ADNP 2 datasets

ChIP K562 ENCFF492SKF 422 bp overlap

ChIP K562 ENCFF492SKF 623 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 161 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 350 bp overlap

ChIP K562 ENCFF938UXQ 311 bp overlap

ARID4A 1 dataset

ChIP Hep-G2 ENCSR386UBO.ARID4A.Hep-G2 157 bp overlap

ChIP K-562 ENCSR613NUC.ARNT.K-562 219 bp overlap

Motif DE_72h DE_72h-Atf3_MA1988.2 7 bp overlap

BACH1 1 dataset

Motif DE_72h DE_72h-BACH1_MA1633.2 9 bp overlap

Motif DE_72h DE_72h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_72h DE_72h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_72h DE_72h-BATFJUN_MA0462.3 7 bp overlap

BCOR 2 datasets

ChIP K-562 ENCSR808AKZ.BCOR.K-562 234 bp overlap

ChIP K562 ENCFF343XWA 233 bp overlap

Motif DE_72h DE_72h-BNC2_MA1928.2 7 bp overlap

ChIP K-562 GSE140325.BRD2.K-562 131 bp overlap

BRD3 3 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 225 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD3.K-562_iBET-BD2-IFNG 357 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD3.K-562_iBET-IFNG 308 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD4.K-562_dilution-6-100 157 bp overlap

ChIP H9 GSE94418.BRF1.H9 157 bp overlap

CBFA2T3 3 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 355 bp overlap

ChIP K-562 GSE142227.CBFA2T3.K-562 192 bp overlap

ChIP K562 ENCFF673OEZ 286 bp overlap

ChIP Hep-G2 ENCSR479RZV.CBFB.Hep-G2 135 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 171 bp overlap

CHAMP1 1 dataset

ChIP K562 ENCFF860ZIW 428 bp overlap

ChIP T-47D GSE62428.CHD8.T-47D 226 bp overlap

DPF2 3 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 415 bp overlap

ChIP K562 ENCFF739JDE 320 bp overlap

ChIP K562 ENCFF775HUO 232 bp overlap

EHMT2 2 datasets

ChIP K-562 ENCSR175EOM.EHMT2.K-562 311 bp overlap

ChIP K562 ENCFF053BWO 316 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 292 bp overlap

EP300 2 datasets

ChIP K-562 ENCSR000EGE.EP300.K-562 150 bp overlap

ChIP K562 ENCFF226VMS 317 bp overlap

ChIP VCaP GSE49091.ERG.VCaP 150 bp overlap

ChIP K562 ENCFF336FFA 497 bp overlap

Motif DE_72h DE_72h-FOS_MA0476.2 8 bp overlap

ChIP K-562 ENCSR000DKB.FOS.K-562 141 bp overlap

FOS::JUN 1 dataset

Motif DE_72h DE_72h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUNB 1 dataset

Motif DE_72h DE_72h-FOSJUNB_MA1134.2 9 bp overlap

FOS::JUND 1 dataset

Motif DE_72h DE_72h-FOSJUND_MA1141.2 9 bp overlap

FOSL1 5 datasets

ChIP BT-549 GSE112961.FOSL1.BT-549 198 bp overlap

Motif DE_72h DE_72h-FOSL1_MA0477.3 9 bp overlap

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 430 bp overlap

ChIP K-562 ENCSR000BMV.FOSL1.K-562 207 bp overlap

ChIP K562 ENCFF455MKD 533 bp overlap

FOSL1::JUN 1 dataset

Motif DE_72h DE_72h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 1 dataset

Motif DE_72h DE_72h-FOSL1JUNB_MA1137.2 9 bp overlap

FOSL1::JUND 1 dataset

Motif DE_72h DE_72h-FOSL1JUND_MA1142.2 8 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 529 bp overlap

ChIP DE DE-FOXA2-2 473 bp overlap

GABPB1 1 dataset

ChIP K562 ENCFF015GDS 211 bp overlap

GATA1 7 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 135 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 135 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 333 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 251 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 272 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 374 bp overlap

GATA2 7 datasets

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 329 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 218 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 126 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 193 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 235 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 669 bp overlap

ChIP DE DE-GATA4-2 704 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 430 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 314 bp overlap

GATA5 1 dataset

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 13 datasets

ChIP DE DE-GATA6-1 764 bp overlap

ChIP DE DE-GATA6-2 694 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 425 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 372 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 387 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 542 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 394 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 439 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 493 bp overlap

ChIP foregut GSE117136.GATA6.foregut 485 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 347 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 140 bp overlap

Gata3 2 datasets

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC1 1 dataset

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 110 bp overlap

HDAC2 4 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 260 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 324 bp overlap

ChIP K562 ENCFF744ALD 299 bp overlap

ChIP K562 ENCFF919OMP 273 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 474 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 221 bp overlap

ChIP K562 ENCFF783OCM 219 bp overlap

HMBOX1 2 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 441 bp overlap

ChIP K562 ENCFF317JJX 487 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 131 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 114 bp overlap

Motif DE_72h DE_72h-JDP2_MA0655.1 9 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 351 bp overlap

JUNB 3 datasets

Motif DE_72h DE_72h-JUNB_MA0490.3 9 bp overlap

ChIP K-562 ENCSR000DJY.JUNB.K-562 266 bp overlap

ChIP K562 ENCFF388SEP 350 bp overlap

JUND 4 datasets

Motif DE_72h DE_72h-JUND_MA0491.3 9 bp overlap

ChIP K-562 ENCSR000EGN.JUND.K-562 210 bp overlap

ChIP K562 ENCFF336RCR 427 bp overlap

ChIP K562 ENCFF830LVJ 281 bp overlap

Motif DE_72h DE_72h-Jun_MA0489.3 8 bp overlap

KDM1A 5 datasets

ChIP H1 ENCFF696SGD 223 bp overlap

ChIP K-562 ENCSR908CMW.KDM1A.K-562 280 bp overlap

ChIP K-562 GSE117944.KDM1A.K-562 232 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 173 bp overlap

ChIP K562 ENCFF128TYE 350 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 374 bp overlap

ChIP K-562 ENCSR343ELW.LEF1.K-562 328 bp overlap

ChIP K-562 ENCSR411UYA.MTA2.K-562 670 bp overlap

MTA3 2 datasets

ChIP K-562 ENCSR914NEI.MTA3.K-562 245 bp overlap

ChIP K562 ENCFF289UFB 378 bp overlap

ChIP K562 ENCFF640IEK 157 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 282 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 259 bp overlap

ChIP hESC GSE18292.NANOG.hESC 101 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 226 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 159 bp overlap

NFE2 2 datasets

Motif DE_72h DE_72h-NFE2_MA0841.2 10 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 165 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 232 bp overlap

NR2F6 3 datasets

ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 204 bp overlap

ChIP HepG2 ENCFF514UJI 247 bp overlap

ChIP K-562 ENCSR707QWA.NR2F6.K-562 147 bp overlap

ONECUT1 2 datasets

ChIP Hep-G2 ENCSR956OSX.ONECUT1.Hep-G2 127 bp overlap

ChIP HepG2 ENCFF243FIR 240 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 227 bp overlap

PRDM10 2 datasets

ChIP K-562 ENCSR120MPG.PRDM10.K-562 204 bp overlap

ChIP K562 ENCFF740YLK 348 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP hippocampus GSE144226.REST.hippocampus 344 bp overlap

RUNX3 1 dataset

ChIP GM12878 ENCFF395WHA 231 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 382 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 286 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 263 bp overlap

SMARCA4 5 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 373 bp overlap

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 320 bp overlap

ChIP K562 ENCFF316MCJ 351 bp overlap

ChIP K562 ENCFF506JCB 133 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 194 bp overlap

SMARCA5 1 dataset

ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 129 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 328 bp overlap

SOX15 1 dataset

Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 487 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 633 bp overlap

ChIP hESC GSE18292.SOX2.hESC 97 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 460 bp overlap

ChIP K562 ENCFF059YCJ 430 bp overlap

STAT5A 1 dataset

ChIP K-562 ENCSR000BRR.STAT5A.K-562 152 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

TAL1 11 datasets

ChIP K-562 GSE107726.TAL1.K-562 327 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 237 bp overlap

ChIP K-562_MYO1D-Non-hub_KO GSE107726.TAL1.K-562_MYO1D-Non-hub_KO 160 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 279 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 282 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 280 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 251 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 193 bp overlap

ChIP K562 ENCFF620GMX 385 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 166 bp overlap

ChIP H1 ENCFF859IIO 269 bp overlap

ChIP K-562 ENCSR000EHA.TBP.K-562 224 bp overlap

ChIP K562 ENCFF901UYM 304 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 158 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 272 bp overlap

ChIP K562 ENCFF931DJY 118 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 228 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 365 bp overlap

TRIM24 2 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 210 bp overlap

ChIP K562 ENCFF616RIL 271 bp overlap

TRIM28 2 datasets

ChIP K-562 ENCSR000BRW.TRIM28.K-562 227 bp overlap

ChIP K-562 ENCSR474CVP.TRIM28.K-562 263 bp overlap

TRPS1 2 datasets

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

XRCC5 2 datasets

ChIP K-562 ENCSR506KWJ.XRCC5.K-562 185 bp overlap

ChIP K-562 GSE120104.XRCC5.K-562 193 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 382 bp overlap

ZBTB40 2 datasets

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 288 bp overlap

ChIP K562 ENCFF521DSV 317 bp overlap

ZBTB5 1 dataset

ChIP K562 ENCFF856PUG 217 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 227 bp overlap

ZFP14 1 dataset

Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap

ZFP91 2 datasets

ChIP K-562 ENCSR898XMH.ZFP91.K-562 298 bp overlap

ChIP K562 ENCFF501CDP 211 bp overlap

ZKSCAN1 2 datasets

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 389 bp overlap

ChIP K562 ENCFF977CBA 293 bp overlap

ZNF24 3 datasets

ChIP K-562 ENCSR695EQB.ZNF24.K-562 309 bp overlap

ChIP K-562 ENCSR099NCH.ZNF24.K-562 261 bp overlap

ChIP K562 ENCFF877JCX 349 bp overlap

ZNF276 1 dataset

ChIP Hep-G2 ENCSR076KLJ.ZNF276.Hep-G2 183 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 200 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 125 bp overlap

ZNF737 1 dataset

ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 245 bp overlap

ZNF865 1 dataset

ChIP HepG2 ENCFF472KAQ 340 bp overlap

ZSCAN29 3 datasets

ChIP K-562 ENCSR175SZH.ZSCAN29.K-562 311 bp overlap

ChIP K562 ENCFF797SOU 280 bp overlap

ChIP K562 ENCFF842XOY 217 bp overlap