chr19:49,432,343–49,432,785

chr19 : 49,432,343 – 49,432,785

442 bp 103 TFs 19 linked genes

This 442 bp open chromatin element is linked to 19 target genes and is bound by 103 transcription factors.

Linked Genes

19 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC17A7		3.4 kb	Proximal	Proximity
GFY		7.0 kb	Proximal	Proximity
PIH1D1		19.3 kb	Distal	Multiome
ALDH16A1		20.7 kb	Distal	Multiome
RPL13A		55.1 kb	Distal	Multiome
RPS11		63.8 kb	Distal	Multiome
TEAD2		71.0 kb	Distal	Multiome
FCGRT		79.8 kb	Distal	Multiome
RCN3		95.5 kb	Distal	Multiome
NOSIP		148.0 kb	Distal	Multiome
PRRG2		148.8 kb	Distal	Multiome
PRR12		158.7 kb	Distal	Multiome
SCAF1		209.7 kb	Distal	Multiome
IRF3		233.3 kb	Distal	Multiome
BCL2L12		233.4 kb	Distal	Multiome
PRMT1		244.7 kb	Distal	Multiome
CPT1C		258.6 kb	Distal	Multiome
TRPM4		274.8 kb	Distal	Multiome
PPFIA3		313.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ChIP NALM-6 GSE93626.AATF.NALM-6 255 bp overlap

AGO1 3 datasets

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 153 bp overlap

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 201 bp overlap

ChIP K-562 ENCSR641BSL.AGO1.K-562 184 bp overlap

ChIP 22Rv1 GSE85558.AR.22Rv1 220 bp overlap

ChIP 22Rv1_Dox GSE85558.AR.22Rv1_Dox 188 bp overlap

ChIP 22Rv1_siARFL_R1881 GSE80742.AR.22Rv1_siARFL_R1881 193 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 122 bp overlap

ChIP breast_tumor_Male_8 GSE104399.AR.breast_tumor_Male_8 252 bp overlap

ChIP breast_tumor_Male_8 GSE104399.AR.breast_tumor_Male_8 95 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 202 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 273 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 442 bp overlap

ChIP H1 ENCFF399KAM 266 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 442 bp overlap

BCL11A 1 dataset

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 54 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 442 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 420 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 442 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 272 bp overlap

BRD4 13 datasets

ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 238 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 442 bp overlap

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 372 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 442 bp overlap

ChIP CLL_patient3_4h_CpG_BET GSE109411.BRD4.CLL_patient3_4h_CpG_BET 351 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 442 bp overlap

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 442 bp overlap

ChIP CLL_patient4_4h_CpG_BET GSE109411.BRD4.CLL_patient4_4h_CpG_BET 351 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 442 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 204 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 137 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 136 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 442 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 76 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 148 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 207 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 269 bp overlap

CTCF 4 datasets

ChIP 22Rv1 ENCFF466OXN 204 bp overlap

ChIP 22Rv1 ENCSR857PBV.CTCF.22Rv1 256 bp overlap

ChIP 22Rv1_hydroxy_10nM_4h ENCSR847XGE.CTCF.22Rv1_hydroxy_10nM_4h 135 bp overlap

ChIP spleen ENCFF065CBS 418 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 442 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 274 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 442 bp overlap

ChIP ProEs GSE59087.EED.ProEs 278 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 179 bp overlap

ESR1 2 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 207 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 303 bp overlap

ChIP WTC11 ENCFF812SCD 421 bp overlap

EZH2 30 datasets

ChIP B-cell ENCSR000AUZ.EZH2.B-cell 442 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 264 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 442 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 442 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 442 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 217 bp overlap

ChIP HepG2 ENCFF912EIW 442 bp overlap

ChIP HepG2 ENCFF912EIW 394 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 442 bp overlap

ChIP RCH-ACV GSE135024.EZH2.RCH-ACV 442 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 113 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 299 bp overlap

ChIP astrocyte ENCFF365JTP 442 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 244 bp overlap

ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 242 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 442 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 326 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 110 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 442 bp overlap

ChIP hepatocyte ENCFF118DKH 240 bp overlap

ChIP hepatocyte ENCFF552DZB 442 bp overlap

ChIP keratinocyte ENCFF070STK 442 bp overlap

ChIP keratinocyte ENCFF070STK 261 bp overlap

ChIP myotube ENCFF857GWB 84 bp overlap

ChIP neural progenitor cell ENCFF018MKA 233 bp overlap

ChIP neural progenitor cell ENCFF018MKA 54 bp overlap

ChIP neural progenitor cell ENCFF018MKA 54 bp overlap

ChIP neural progenitor cell ENCFF472NFV 442 bp overlap

ChIP neural progenitor cell ENCFF472NFV 442 bp overlap

ChIP peripheral-blood-mononuclear-cell_B-cell GSE115772.EZH2.peripheral-blood-mononuclear-cell_B-cell 375 bp overlap

EZH2_phosphoT487 5 datasets

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 94 bp overlap

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 154 bp overlap

ChIP SK-N-SH ENCSR297MUV.EZH2_phosphoT487.SK-N-SH 92 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 442 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 331 bp overlap

FOXA1 2 datasets

ChIP LS180 GSE140533.FOXA1.LS180 71 bp overlap

ChIP breast-cancer_heregulin-Herceptin-ICI GSE101407.FOXA1.breast-cancer_heregulin-Herceptin-ICI 432 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 308 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP4 3 datasets

ChIP K562 ENCFF086EQT 259 bp overlap

ChIP WTC11 ENCFF708TAF 377 bp overlap

ChIP WTC11 ENCFF708TAF 177 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 131 bp overlap

GATA2 1 dataset

ChIP ME-1 GSE46044.GATA2.ME-1 285 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 442 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 284 bp overlap

JARID2 3 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 242 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 60 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 71 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 285 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 399 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 442 bp overlap

KDM4A 6 datasets

ChIP H1 ENCFF078LED 368 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 53 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 353 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 176 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 271 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 251 bp overlap

KDM6B 2 datasets

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 303 bp overlap

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 57 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCFF159QSW 197 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 69 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 442 bp overlap

KLF4 2 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 184 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 151 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 329 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP WTC11 ENCFF223QFY 442 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 275 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 442 bp overlap

ChIP BJ_INDUCED GSE36570.MYC.BJ_INDUCED 97 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 90 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 442 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 369 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 345 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 182 bp overlap

NR2C2 1 dataset

ChIP WTC11 ENCFF896ODS 252 bp overlap

ChIP HMEC-1 GSE67867.NRF1.HMEC-1 187 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 442 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 442 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 277 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 398 bp overlap

PCBP1 2 datasets

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 281 bp overlap

ChIP Hep-G2 ENCSR872EVQ.PCBP1.Hep-G2 245 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 442 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 152 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 249 bp overlap

POU2F1 1 dataset

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 209 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 181 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 442 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 442 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 137 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 442 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 442 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 360 bp overlap

RAD21 1 dataset

ChIP hiPSC_IIA11 GSE106870.RAD21.hiPSC_IIA11 131 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 313 bp overlap

RBM14,RBM14-RBM4 2 datasets

ChIP K562 ENCFF118FCO 349 bp overlap

ChIP K562 ENCFF857JAI 386 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 118 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 399 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 206 bp overlap

RUNX1 1 dataset

ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 185 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 442 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 343 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 359 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 303 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 159 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 442 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 231 bp overlap

SMAD2_3 2 datasets

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 64 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 425 bp overlap

SMARCA4 3 datasets

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 257 bp overlap

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 442 bp overlap

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 253 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 273 bp overlap

ChIP DKO GSE131606.SMC1.DKO 108 bp overlap

SNAI2 1 dataset

ChIP keratinocyte_SNAI2 GSE55421.SNAI2.keratinocyte_SNAI2 205 bp overlap

ChIP WTC11 ENCFF688PEU 442 bp overlap

ChIP ME-1 GSE46044.SPI1.ME-1 247 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 258 bp overlap

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 336 bp overlap

SRSF7 1 dataset

ChIP Hep-G2 GSE120104.SRSF7.Hep-G2 238 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 218 bp overlap

SUZ12 5 datasets

ChIP GM12878 ENCSR744XTG.SUZ12.GM12878 442 bp overlap

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 442 bp overlap

ChIP H1 ENCFF881NFR 442 bp overlap

ChIP H1 ENCFF881NFR 437 bp overlap

ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 286 bp overlap

TAF1 3 datasets

ChIP H1 ENCFF478SZO 442 bp overlap

ChIP H1 ENCFF478SZO 273 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 244 bp overlap

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 176 bp overlap

TARDBP 2 datasets

ChIP Hep-G2 ENCSR145CXH.TARDBP.Hep-G2 172 bp overlap

ChIP Hep-G2 GSE120104.TARDBP.Hep-G2 160 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 238 bp overlap

ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 441 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 325 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 241 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 169 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 278 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 312 bp overlap

ChIP WTC11 ENCFF699QGS 227 bp overlap

USF2 2 datasets

ChIP WTC11 ENCFF139JAW 184 bp overlap

ChIP WTC11 ENCFF139JAW 387 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 320 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 187 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 442 bp overlap

ChIP K562 ENCFF427SDV 440 bp overlap

ChIP K562 ENCFF875HLX 308 bp overlap

ZBTB48 2 datasets

ChIP U2OS GSE96776.ZBTB48.U2OS 342 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 375 bp overlap

ZEB1 3 datasets

ChIP GM12878 ENCFF148RLQ 311 bp overlap

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 423 bp overlap

ChIP RKO GSE88734.ZEB1.RKO 291 bp overlap

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 441 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 170 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 430 bp overlap

ZNF445 1 dataset

ChIP HEK293T GSE78099.ZNF445.HEK293T 347 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 90 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 321 bp overlap