Predicted to be involved in sensory perception of smell. Predicted to act upstream of or within non-motile cilium assembly and protein localization to non-motile cilium. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for GFY. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GFY upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GFY, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:49,421,051–49,421,452 | 3.9 kb | Proximal (<10kb) | 237 | |
| chr19:49,422,427–49,422,706 | 2.7 kb | Proximal (<10kb) | 348 | |
| chr19:49,426,218–49,426,471 | 830 bp | At TSS | 231 | |
| chr19:49,428,284–49,428,666 | 2.9 kb | Proximal (<10kb) | 164 | |
| chr19:49,432,343–49,432,785 | 7.0 kb | Proximal (<10kb) | 103 |
Genomic view of the GFY locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.