chr13:41,085,849–41,086,392

chr13 : 41,085,849 – 41,086,392

543 bp 126 TFs 8 linked genes

This 543 bp open chromatin element is linked to 8 target genes and is bound by 126 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
WBP4		24.6 kb	Distal	Multiome
ELF1		24.7 kb	Distal	Multiome
KBTBD6		46.7 kb	Distal	Multiome
KBTBD7		108.5 kb	Distal	Multiome+HiCAR
ENSG00000290476		164.4 kb	Distal	Multiome
MTRF1		177.5 kb	Distal	Multiome
NAA16		225.2 kb	Distal	Multiome
SLC25A15		296.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

126 transcription factors

ChIP breast_tumor_Male_20 GSE104399.AR.breast_tumor_Male_20 203 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 190 bp overlap

ChIP K-562 GSE140325.BRD2.K-562 71 bp overlap

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 286 bp overlap

CEBPA 1 dataset

ChIP SKH1_RUNX1-EVI1_KD GSE87283.CEBPA.SKH1_RUNX1-EVI1_KD 150 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 127 bp overlap

CREBBP 1 dataset

ChIP MCF-7 ERP000901.CREBBP.MCF-7 81 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 265 bp overlap

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

Motif DE_12h DE_12h-DPRX_MA1480.2 9 bp overlap

Dmbx1 1 dataset

Motif DE_12h DE_12h-Dmbx1_MA0883.2 10 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 169 bp overlap

Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap

Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap

Motif DE_12h DE_12h-ELK4_MA0076.3 9 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

ESR1 7 datasets

ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 235 bp overlap

ChIP MCF-7_E2+4OHT GSE119702.ESR1.MCF-7_E2+4OHT 325 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 190 bp overlap

ChIP MCF-7_OHT GSE119702.ESR1.MCF-7_OHT 325 bp overlap

ChIP MCF-7_shCtrl GSE125594.ESR1.MCF-7_shCtrl 180 bp overlap

ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 265 bp overlap

ChIP MCF-7_shYAP1 GSE125594.ESR1.MCF-7_shYAP1 259 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 216 bp overlap

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

Motif DE_12h DE_12h-ETV6_MA0645.2 9 bp overlap

Motif DE_12h DE_12h-ETV7_MA1708.2 9 bp overlap

EVI1 2 datasets

ChIP SKH1 GSE87283.EVI1.SKH1 87 bp overlap

ChIP SKH1_10d GSE87283.EVI1.SKH1_10d 179 bp overlap

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 244 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 168 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GATA1 1 dataset

Motif DE_12h DE_12h-GATA1_MA0035.5 7 bp overlap

GATA2 1 dataset

ChIP SKH1 GSE87283.GATA2.SKH1 150 bp overlap

GATA6 5 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 412 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 534 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 420 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 537 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 507 bp overlap

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

Motif DE_12h DE_12h-HLF_MA0043.4 9 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 211 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 253 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 272 bp overlap

ChIP K-562 ENCSR000DJY.JUNB.K-562 87 bp overlap

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

KLF13 1 dataset

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap

KLF4 6 datasets

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 224 bp overlap

ChIP WA09 GSE105028.KLF4.WA09 333 bp overlap

ChIP WA09_heat-shock GSE105028.KLF4.WA09_heat-shock 262 bp overlap

ChIP WIBR3 GSE130417.KLF4.WIBR3 216 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 330 bp overlap

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap

KLF9 2 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 108 bp overlap

LDB1 2 datasets

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 88 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 85 bp overlap

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 153 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 141 bp overlap

MEIS2 1 dataset

Motif DE_12h DE_12h-MEIS2_MA1640.2 9 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 441 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 322 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 543 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 514 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 360 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 123 bp overlap

NFIL3 1 dataset

Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 231 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 364 bp overlap

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

Motif DE_12h DE_12h-PBX2_MA1113.3 9 bp overlap

PHOX2B 1 dataset

Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 16 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 365 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 458 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 402 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 524 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 191 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 232 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 222 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 219 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 496 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 409 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 298 bp overlap

ChIP hiPSC GSE149017.POU5F1.hiPSC 192 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 187 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 350 bp overlap

PRDM14 1 dataset

ChIP hESC GSE22767.PRDM14.hESC 499 bp overlap

PROP1 1 dataset

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE126634.RAD21.HAP1 299 bp overlap

Motif DE_12h DE_12h-RFX4_MA0799.3 13 bp overlap

RFX5 6 datasets

ChIP H1 ENCFF605EGG 342 bp overlap

ChIP IMR-90 ENCFF886KPO 277 bp overlap

ChIP IMR-90 ENCSR000EFD.RFX5.IMR-90 189 bp overlap

ChIP MCF-7 ENCFF983ILY 336 bp overlap

ChIP MCF-7 ENCSR924TVL.RFX5.MCF-7 266 bp overlap

ChIP WA01 ENCSR000ECF.RFX5.WA01 260 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_12h DE_12h-RORB_MA1150.2 10 bp overlap

Motif DE_12h DE_12h-RORC_MA1151.2 10 bp overlap

RUNX1 3 datasets

ChIP Jurkat GSE68976.RUNX1.Jurkat 173 bp overlap

ChIP MV4-11 GSE79899.RUNX1.MV4-11 90 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 162 bp overlap

SATB1 1 dataset

Motif DE_12h DE_12h-SATB1_MA1963.2 7 bp overlap

SIN3A 3 datasets

ChIP SK-N-SH ENCSR000BPB.SIN3A.SK-N-SH 119 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 133 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 172 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 277 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 299 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 514 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 428 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 537 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 362 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 364 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 374 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 185 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 202 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 231 bp overlap

SOX2 2 datasets

ChIP hESC GSE69479.SOX2.hESC 196 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 349 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 190 bp overlap

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

SREBF2 2 datasets

Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap

Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap

SUPT5H 1 dataset

ChIP MOLT-4_SNS GSE89384.SUPT5H.MOLT-4_SNS 414 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 275 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 110 bp overlap

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TCF3 2 datasets

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 106 bp overlap

ChIP NPC GSE154479.TCF3.NPC 256 bp overlap

TP53 2 datasets

ChIP SW480_shp53_16h_TNF-a GSE115985.TP53.SW480_shp53_16h_TNF-a 253 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 237 bp overlap

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZBTB11 1 dataset

Motif DE_12h DE_12h-ZBTB11_MA2329.1 9 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZBTB7A 1 dataset

Motif DE_12h DE_12h-ZBTB7A_MA0750.3 9 bp overlap

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZKSCAN3 1 dataset

Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF175 1 dataset

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

ZNF35 1 dataset

Motif DE_12h DE_12h-ZNF35_MA2333.1 7 bp overlap

ZNF354C 1 dataset

Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 231 bp overlap

ZNF682 1 dataset

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 278 bp overlap

ZNF766 1 dataset

Motif DE_12h DE_12h-ZNF766_MA2098.1 9 bp overlap