chr8:22,069,764–22,070,311

chr8 : 22,069,764 – 22,070,311

547 bp 85 TFs 8 linked genes

This 547 bp open chromatin element is linked to 8 target genes and is bound by 85 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
DMTN		3.2 kb	Proximal	Proximity
FHIP2B		19.1 kb	Distal	Multiome
REEP4		71.8 kb	Distal	Multiome
BMP1		95.2 kb	Distal	Multiome
XPO7		150.3 kb	Distal	Multiome
POLR3D		175.1 kb	Distal	Multiome
PIWIL2		205.2 kb	Distal	Multiome
SLC39A14		297.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ChIP NALM-6 GSE93626.AATF.NALM-6 208 bp overlap

ARNT 2 datasets

ChIP MCF-7_Ctrl GSE85352.ARNT.MCF-7_Ctrl 409 bp overlap

ChIP MCF-7_aza GSE85352.ARNT.MCF-7_aza 497 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 547 bp overlap

ChIP H1 ENCFF399KAM 455 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 471 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 154 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 201 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 170 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 269 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 530 bp overlap

BRD4 3 datasets

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 249 bp overlap

ChIP OVCAR-3_DMSO GSE77568.BRD4.OVCAR-3_DMSO 384 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 424 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 133 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 171 bp overlap

CREB1 4 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 190 bp overlap

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 234 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 261 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 222 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 329 bp overlap

ChIP HEK293 ENCFF336LFH 194 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 302 bp overlap

ChIP HUVEC-C GSE124891.ERG.HUVEC-C 149 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 221 bp overlap

ESR1 5 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 221 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 226 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 224 bp overlap

ChIP MCF-7_Veh GSE67295.ESR1.MCF-7_Veh 244 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 171 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 140 bp overlap

ESR1_Y537S 1 dataset

ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 174 bp overlap

ETS1 2 datasets

ChIP GM23338 ENCFF701IZH 377 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 258 bp overlap

EZH2 10 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 72 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 116 bp overlap

ChIP H1 ENCFF232NZA 431 bp overlap

ChIP H1 ENCFF232NZA 547 bp overlap

ChIP H1 ENCFF232NZA 547 bp overlap

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 296 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 547 bp overlap

ChIP neural progenitor cell ENCFF018MKA 235 bp overlap

ChIP neural progenitor cell ENCFF472NFV 547 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 435 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 512 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 364 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 374 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 426 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 419 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 118 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 336 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 170 bp overlap

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 120 bp overlap

JARID2 3 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 451 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 410 bp overlap

ChIP UTEIPS7 GSE48516.JARID2.UTEIPS7 223 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 269 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 393 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 324 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 524 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 383 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 547 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 409 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 388 bp overlap

ChIP H1 ENCFF914VQY 226 bp overlap

ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 120 bp overlap

ChIP WTC11 ENCFF223QFY 525 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 320 bp overlap

ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 408 bp overlap

ChIP Kelly GSE94782.MYCN.Kelly 122 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 302 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 547 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 278 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 371 bp overlap

ChIP WTC11 ENCFF751ZTQ 338 bp overlap

NR2F2 1 dataset

ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 146 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 383 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 293 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 317 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 196 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 386 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 208 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 495 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 452 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 225 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 152 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 547 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 298 bp overlap

RAD21 1 dataset

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 259 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 266 bp overlap

RBFOX2 4 datasets

ChIP HepG2 ENCFF554DMZ 306 bp overlap

ChIP HepG2 ENCFF939HTZ 306 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 386 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 204 bp overlap

RBM39 2 datasets

ChIP Hep-G2 ENCSR339JTP.RBM39.Hep-G2 77 bp overlap

ChIP Hep-G2 GSE120104.RBM39.Hep-G2 77 bp overlap

ChIP MCF-7_IL1b_45m GSE67295.RELA.MCF-7_IL1b_45m 181 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 497 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 198 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 205 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 308 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 204 bp overlap

SIN3A 2 datasets

ChIP H1 ENCFF042ZSL 475 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 193 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 400 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 411 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 398 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 547 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 483 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 254 bp overlap

SMARCA4 2 datasets

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 141 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 169 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 170 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 239 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 245 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 226 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 191 bp overlap

SUZ12 3 datasets

ChIP H1 ENCFF881NFR 547 bp overlap

ChIP Karpas-422_CPI360-D8 GSE134136.SUZ12.Karpas-422_CPI360-D8 217 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 244 bp overlap

TAF15 1 dataset

ChIP K-562 ENCSR047LSJ.TAF15.K-562 213 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 246 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 351 bp overlap

ChIP NPC GSE154479.TCF3.NPC 466 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 255 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 217 bp overlap

TFAP2C 1 dataset

ChIP WA09 GSE105081.TFAP2C.WA09 199 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 345 bp overlap

TP63 2 datasets

ChIP breast-organoid GSE113909.TP63.breast-organoid 124 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 189 bp overlap

USF1 3 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 209 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 139 bp overlap

ZBTB43 2 datasets

ChIP WTC11 ENCFF058JUB 462 bp overlap

ChIP WTC11 ENCFF058JUB 364 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 78 bp overlap

ZEB1 3 datasets

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 265 bp overlap

ChIP MIA-PaCa-2 GSE88734.ZEB1.MIA-PaCa-2 316 bp overlap

ChIP RKO GSE88734.ZEB1.RKO 373 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 155 bp overlap

ZNF143 5 datasets

ChIP MCF-7 GSE76454.ZNF143.MCF-7 240 bp overlap

ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 227 bp overlap

ChIP WA01 ENCSR000EBW.ZNF143.WA01 176 bp overlap

ChIP WA09 GSE105028.ZNF143.WA09 192 bp overlap

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 222 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 248 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 339 bp overlap

ZNF281 1 dataset

ChIP WTC11 ENCFF551GAV 377 bp overlap

ZNF398 1 dataset

ChIP BG01V GSE133630.ZNF398.BG01V 193 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 145 bp overlap