chr1:113,043,627–113,044,178

chr1 : 113,043,627 – 113,044,178

551 bp 105 TFs 5 linked genes

This 551 bp open chromatin element is linked to 5 target genes and is bound by 105 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LRIG2-DT		29.1 kb	Distal	Multiome
LRIG2		29.2 kb	Distal	Multiome
SLC16A1-AS1		87.6 kb	Distal	Multiome+HiCAR
SLC16A1		87.8 kb	Distal	Multiome+HiCAR
LINC01356		194.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

ChIP MCF-7 GSE48930.AR.MCF-7 406 bp overlap

ASCL1 1 dataset

Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 230 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 438 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 244 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 335 bp overlap

BRD2 3 datasets

ChIP HUVEC-C GSE60171.BRD2.HUVEC-C 195 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD2.MV4-11_IBET151_50nM 141 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 249 bp overlap

BRD3 2 datasets

ChIP HUVEC-C GSE60171.BRD3.HUVEC-C 274 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 274 bp overlap

BRD4 10 datasets

ChIP HUVEC-C GSE60171.BRD4.HUVEC-C 232 bp overlap

ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 255 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 203 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 298 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 272 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 474 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 170 bp overlap

ChIP SGBS GSE64233.BRD4.SGBS 167 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 210 bp overlap

ChIP hESC GSE33281.BRD4.hESC 86 bp overlap

ChIP H9 GSE94418.BRF1.H9 211 bp overlap

ChIP KB_IL GSE52469.CDK6.KB_IL 171 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 146 bp overlap

CREBBP 2 datasets

ChIP PC-3 GSE147455.CREBBP.PC-3 162 bp overlap

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 209 bp overlap

CSNK2A1 1 dataset

ChIP LNCaP_DHT GSE58607.CSNK2A1.LNCaP_DHT 180 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 240 bp overlap

CTCF 3 datasets

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 167 bp overlap

ChIP epithelial_proximal_tubule ENCSR000DXD.CTCF.epithelial_proximal_tubule 143 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 251 bp overlap

ChIP PC-3 GSE68647.DAXX.PC-3 180 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 306 bp overlap

ChIP H1 ENCFF785DWK 50 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 136 bp overlap

EGR1 2 datasets

ChIP K562 ENCFF895KGN 174 bp overlap

ChIP macrophage_D3 GSE136216.EGR1.macrophage_D3 248 bp overlap

ChIP HEK293 ENCFF336LFH 260 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 303 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP PC-3 GSE147455.EP300.PC-3 95 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 198 bp overlap

ESR1 3 datasets

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 281 bp overlap

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 95 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 159 bp overlap

ChIP WTC11 ENCFF812SCD 355 bp overlap

FEZF1 1 dataset

ChIP HEK293 GSE76494.FEZF1.HEK293 210 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 339 bp overlap

ChIP DE DE-GATA6-2 396 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 543 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 327 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 394 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 442 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 449 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 502 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 311 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 429 bp overlap

HDAC2 2 datasets

ChIP PC-3 GSE147455.HDAC2.PC-3 468 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 115 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 116 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 207 bp overlap

HNRNPUL1 2 datasets

ChIP K-562 GSE120104.HNRNPUL1.K-562 220 bp overlap

ChIP K-562 ENCSR296MXW.HNRNPUL1.K-562 199 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 424 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 407 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 432 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 292 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 294 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 396 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 481 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 201 bp overlap

KLF12 1 dataset

ChIP HepG2 ENCFF395LSO 257 bp overlap

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

MED1 7 datasets

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 392 bp overlap

ChIP SGBS GSE64233.MED1.SGBS 385 bp overlap

ChIP SGBS_TNF GSE64233.MED1.SGBS_TNF 376 bp overlap

ChIP adipocyte GSE140782.MED1.adipocyte 258 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 292 bp overlap

ChIP hMSC-TERT4_D1 GSE104537.MED1.hMSC-TERT4_D1 263 bp overlap

ChIP hMSC-TERT4_adipocyte-D14 GSE113253.MED1.hMSC-TERT4_adipocyte-D14 330 bp overlap

ChIP K-562 ENCSR411UYA.MTA2.K-562 287 bp overlap

ChIP THP-1 GSE90769.MYB.THP-1 215 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 551 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 350 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 119 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 476 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 389 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 284 bp overlap

NELFE 1 dataset

ChIP HeLa GSE125534.NELFE.HeLa 119 bp overlap

NIPBL 1 dataset

ChIP WA09 GSE105028.NIPBL.WA09 265 bp overlap

NR1H3 1 dataset

ChIP SGBS GSE41629.NR1H3.SGBS 349 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

ChIP WTC11 ENCFF634NAO 218 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 327 bp overlap

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 246 bp overlap

POLR2A 1 dataset

ChIP transverse colon ENCFF610RWV 406 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 221 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 339 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 532 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 355 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 429 bp overlap

PPARG 2 datasets

ChIP ASC GSE21366.PPARG.ASC 289 bp overlap

ChIP SGBS GSE41629.PPARG.SGBS 336 bp overlap

Prdm5 2 datasets

Motif DE_12h DE_12h-Prdm5_MA1999.2 11 bp overlap

Motif DE_12h DE_12h-Prdm5_MA1999.2 11 bp overlap

RAD21 2 datasets

ChIP HCT-116 GSE131606.RAD21.HCT-116 297 bp overlap

ChIP WA09 GSE105028.RAD21.WA09 174 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 396 bp overlap

RBM39 1 dataset

ChIP K-562 ENCSR764OXF.RBM39.K-562 252 bp overlap

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 145 bp overlap

ChIP macrophage ERP008801.RXR.macrophage 199 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 345 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 325 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 355 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 423 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap

ChIP WTC11 ENCFF815YYQ 357 bp overlap

SMARCA4 5 datasets

ChIP NSC GSE125033.SMARCA4.NSC 412 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 215 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 245 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 266 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 436 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 414 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 298 bp overlap

SMARCC1 5 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 253 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 340 bp overlap

ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 119 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 234 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 292 bp overlap

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.SMC3.HeLa-Kyoto_WAPL_PDS-depleted 187 bp overlap

SNAI1 1 dataset

Motif DE_12h DE_12h-SNAI1_MA1558.2 7 bp overlap

SNAI2 2 datasets

ChIP RD_shSNAI2 GSE137168.SNAI2.RD_shSNAI2 214 bp overlap

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 180 bp overlap

SNAI3 1 dataset

Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap

SNRNP70 1 dataset

ChIP K-562 ENCSR754ZHU.SNRNP70.K-562 269 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 413 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 227 bp overlap

ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 328 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 228 bp overlap

ChIP WTC11 ENCFF688PEU 350 bp overlap

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

SUPT5H 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 422 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 183 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 139 bp overlap

ChIP hESC GSE122298.TBP.hESC 249 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 241 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 166 bp overlap

TCF12 3 datasets

Motif DE_12h DE_12h-TCF12_MA1648.2 7 bp overlap

ChIP H1 ENCFF203EBH 234 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 160 bp overlap

Motif DE_12h DE_12h-TCF3_MA0522.4 7 bp overlap

Motif DE_12h DE_12h-TCF4_MA0830.3 8 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 285 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 171 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 452 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 420 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 174 bp overlap

ChIP kidney-cortex GSE129585.VDR.kidney-cortex 387 bp overlap

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 154 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 256 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 217 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 102 bp overlap

ZBTB8A 2 datasets

ChIP HEK293 ENCFF303WRD 164 bp overlap

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 277 bp overlap

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 305 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF143 1 dataset

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 147 bp overlap

ZNF281 3 datasets

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ChIP K-562 GSE121133.ZNF281.K-562 198 bp overlap

ChIP WTC11 ENCFF551GAV 371 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 155 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 462 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 154 bp overlap

ZNF512 2 datasets

ChIP K562 ENCFF601EMZ 236 bp overlap

ChIP K562 ENCFF601EMZ 442 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 474 bp overlap

ZNF684 2 datasets

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

ZNF697 1 dataset

ChIP Hep-G2 ENCSR734WFB.ZNF697.Hep-G2 168 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZNF76 1 dataset

Motif DE_12h DE_12h-ZNF76_MA1716.2 17 bp overlap

ZNF883 1 dataset

ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 153 bp overlap