chr19:1,851,701–1,852,216

chr19 : 1,851,701 – 1,852,216

515 bp 115 TFs 14 linked genes

This 515 bp open chromatin element is linked to 14 target genes and is bound by 115 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
REXO1		3.2 kb	Proximal	Proximity
KLF16		11.6 kb	Distal	Multiome
ENSG00000261526		24.2 kb	Distal	Multiome
ABHD17A		33.5 kb	Distal	Multiome
SCAMP4		53.4 kb	Distal	Multiome
CSNK1G2		89.2 kb	Distal	Multiome
BTBD2		182.9 kb	Distal	Multiome
MKNK2		199.3 kb	Distal	Multiome
TCF3		199.3 kb	Distal	Multiome
MOB3A		244.4 kb	Distal	Multiome
UQCR11		246.5 kb	Distal	Multiome
MBD3		259.1 kb	Distal	Multiome
MEX3D		283.6 kb	Distal	Multiome
AP3D1		299.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

115 transcription factors

ChIP SEM_DMSO GSE90762.AFF1.SEM_DMSO 368 bp overlap

AGO1 4 datasets

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 515 bp overlap

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 515 bp overlap

ChIP K-562 GSE120104.AGO1.K-562 362 bp overlap

ChIP K-562 ENCSR641BSL.AGO1.K-562 372 bp overlap

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 515 bp overlap

ChIP HepG2 ENCFF773YDL 515 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 142 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 515 bp overlap

ARNTL 2 datasets

ChIP GSC_3565 GSE134972.ARNTL.GSC_3565 515 bp overlap

ChIP GSC_387 GSE134972.ARNTL.GSC_387 284 bp overlap

ASXL3 1 dataset

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 215 bp overlap

BCL11B 1 dataset

ChIP thymus_CD34neg GSE84677.BCL11B.thymus_CD34neg 121 bp overlap

ChIP CD4 GSE59933.BCL6.CD4 121 bp overlap

BRD4 20 datasets

ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 274 bp overlap

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 192 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 515 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 80 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 286 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 332 bp overlap

ChIP Jurkat GSE83777.BRD4.Jurkat 196 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 408 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 95 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 335 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 127 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 217 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 408 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 444 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 402 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 515 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 515 bp overlap

ChIP SEM GSE83671.BRD4.SEM 265 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 391 bp overlap

ChIP retina_AB1-FW13 GSE86981.BRD4.retina_AB1-FW13 258 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 119 bp overlap

ChIP SCMC GSE155861.CHD4.SCMC 327 bp overlap

CTCF 16 datasets

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 237 bp overlap

ChIP B cell ENCFF500PZO 161 bp overlap

ChIP B cell ENCFF500PZO 431 bp overlap

ChIP CD14 ENCSR000ATN.CTCF.CD14 197 bp overlap

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 308 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 368 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 130 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 189 bp overlap

ChIP Jurkat_GSI3d GSE130140.CTCF.Jurkat_GSI3d 161 bp overlap

ChIP Kelly_resistant GSE103030.CTCF.Kelly_resistant 281 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 193 bp overlap

ChIP NB69 GSE101295.CTCF.NB69 231 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 162 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-pos 145 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 408 bp overlap

ChIP peripheral-blood-neutrophil_US-1 GSE126755.CTCF.peripheral-blood-neutrophil_US-1 87 bp overlap

CTCFL 5 datasets

ChIP K-562 GSE70764.CTCFL.K-562 107 bp overlap

ChIP K-562 GSE70764.CTCFL.K-562 279 bp overlap

ChIP Kelly_resistant GSE103030.CTCFL.Kelly_resistant 108 bp overlap

ChIP Kelly_shLUC-res GSE115248.CTCFL.Kelly_shLUC-res 134 bp overlap

ChIP delta-47 GSE70764.CTCFL.delta-47 219 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 319 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 312 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 87 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 117 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 242 bp overlap

EGR1 3 datasets

ChIP GM12878 ENCFF092DJY 211 bp overlap

ChIP GM12878 ENCSR000BMQ.EGR1.GM12878 204 bp overlap

ChIP K-562 ENCSR000BNE.EGR1.K-562 147 bp overlap

ELF1 2 datasets

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 249 bp overlap

ChIP SK-N-MC_SHFLI_96H GSE61944.ELF1.SK-N-MC_SHFLI_96H 295 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 117 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 242 bp overlap

ChIP K-562 GSE23730.ERG.K-562 182 bp overlap

ChIP SEM GSE117864.ERG.SEM 515 bp overlap

FIP1L1 3 datasets

ChIP K-562 ENCSR177DNR.FIP1L1.K-562 159 bp overlap

ChIP K-562 GSE120104.FIP1L1.K-562 159 bp overlap

ChIP K562 ENCFF363ZMN 328 bp overlap

FLI1 4 datasets

ChIP A-673 GSE99959.FLI1.A-673 236 bp overlap

ChIP SEM GSE117864.FLI1.SEM 195 bp overlap

ChIP SK-N-MC_SHGFP_48H GSE61944.FLI1.SK-N-MC_SHGFP_48H 272 bp overlap

ChIP SK-N-MC_SHGFP_96H GSE61944.FLI1.SK-N-MC_SHGFP_96H 235 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 111 bp overlap

GATA3 1 dataset

ChIP MCF-7 GSE128445.GATA3.MCF-7 155 bp overlap

GLIS2 1 dataset

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 515 bp overlap

HAND2 1 dataset

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 210 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 417 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 277 bp overlap

HMGB1 1 dataset

ChIP HUVEC-C GSE98245.HMGB1.HUVEC-C 247 bp overlap

HNRNPK 2 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 130 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 121 bp overlap

HNRNPL 5 datasets

ChIP K-562 ENCSR594BNR.HNRNPL.K-562 250 bp overlap

ChIP K-562 GSE120104.HNRNPL.K-562 174 bp overlap

ChIP K562 ENCFF296JLL 477 bp overlap

ChIP K562 ENCFF296JLL 306 bp overlap

ChIP K562 ENCFF779NTZ 477 bp overlap

IFNA1 1 dataset

ChIP Huh-7_NS5 GSE110511.IFNA1.Huh-7_NS5 138 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 255 bp overlap

IKZF3 1 dataset

ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 254 bp overlap

ChIP CD4 GSE116695.JUNB.CD4 130 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 430 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 81 bp overlap

KDM6B 2 datasets

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 209 bp overlap

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 237 bp overlap

KLF14 1 dataset

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 179 bp overlap

KLF8 2 datasets

ChIP HEK293 ENCFF929IAJ 162 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 174 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 208 bp overlap

KMT2A 2 datasets

ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 375 bp overlap

ChIP blood_cord GSE83671.KMT2A.blood_cord 350 bp overlap

KMT2D 1 dataset

ChIP BIN-67_ctrl GSE117734.KMT2D.BIN-67_ctrl 280 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 258 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 234 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 116 bp overlap

ChIP H1 ENCFF914VQY 130 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 254 bp overlap

ChIP P493-6_24HR GSE125863.MAX.P493-6_24HR 494 bp overlap

ChIP SEM GSE83671.MED.SEM 431 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 170 bp overlap

MEIS1 1 dataset

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 238 bp overlap

ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 193 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 369 bp overlap

ChIP MOLT-3 GSE59657.MYB.MOLT-3 394 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 515 bp overlap

ChIP P493-6_4HR GSE125863.MYC.P493-6_4HR 250 bp overlap

MYCN 5 datasets

ChIP BE2C GSE80151.MYCN.BE2C 216 bp overlap

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 185 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 250 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 236 bp overlap

ChIP SK-N-BE2-C GSE80151.MYCN.SK-N-BE2-C 213 bp overlap

NCAPH2 2 datasets

ChIP IMR-90_Bethyl275_G GSE118494.NCAPH2.IMR-90_Bethyl275_G 190 bp overlap

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 515 bp overlap

NELFE 2 datasets

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 143 bp overlap

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 77 bp overlap

Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 76 bp overlap

NOTCH1 2 datasets

ChIP CUTLL1 GSE29600.NOTCH1.CUTLL1 241 bp overlap

ChIP HPBALL GSE39263.NOTCH1.HPBALL 372 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 330 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 440 bp overlap

ChIP Namalwa GSE53133.NRF1.Namalwa 229 bp overlap

OGG1 2 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 216 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 203 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 453 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 291 bp overlap

Motif DE_24h DE_24h-PBX3_MA1114.2 11 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 119 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 515 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 134 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 135 bp overlap

ChIP spleen ENCFF706IUS 177 bp overlap

ChIP spleen ENCFF706IUS 307 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 515 bp overlap

ChIP K562 ENCFF648YPL 515 bp overlap

POU5F1 6 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 515 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 389 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 90 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 184 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 122 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 267 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 515 bp overlap

RAD21 1 dataset

ChIP HCT-116 GSE131606.RAD21.HCT-116 107 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 125 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 89 bp overlap

RBFOX2 4 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 515 bp overlap

ChIP K562 ENCFF196WTG 207 bp overlap

ChIP K562 ENCFF967GRF 202 bp overlap

ChIP K562 ENCFF967GRF 145 bp overlap

RBM22 1 dataset

ChIP K-562 ENCSR848AOP.RBM22.K-562 515 bp overlap

Motif DE_24h DE_24h-RFX4_MA0799.3 13 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 515 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 515 bp overlap

RUNX1 5 datasets

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 300 bp overlap

ChIP H9_DOX-5_HA GSE137670.RUNX1.H9_DOX-5_HA 178 bp overlap

ChIP Jurkat GSE76181.RUNX1.Jurkat 233 bp overlap

ChIP NALM-6 GSE126300.RUNX1.NALM-6 360 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 249 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 133 bp overlap

Motif DE_24h DE_24h-Rfx6_MA1724.2 9 bp overlap

SIRT6 2 datasets

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 92 bp overlap

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 207 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 285 bp overlap

SMARCA4 1 dataset

ChIP MCF-10A GSE74716.SMARCA4.MCF-10A 98 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 515 bp overlap

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 286 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 515 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 515 bp overlap

SSRP1 1 dataset

ChIP HT-1080_AclacinomycinA GSE107595.SSRP1.HT-1080_AclacinomycinA 236 bp overlap

STAG1 1 dataset

ChIP erythroid GSE67783.STAG1.erythroid 397 bp overlap

SUPT5H 6 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 375 bp overlap

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 67 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 56 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 342 bp overlap

ChIP U2OS_siCtrl GSE115365.SUPT5H.U2OS_siCtrl 124 bp overlap

ChIP U2OS_siMYC_ON GSE115365.SUPT5H.U2OS_siMYC_ON 99 bp overlap

SUPT6H 1 dataset

ChIP HCT-116 GSE130509.SUPT6H.HCT-116 353 bp overlap

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 232 bp overlap

TARDBP 1 dataset

ChIP Hep-G2 ENCSR145CXH.TARDBP.Hep-G2 113 bp overlap

TBX2 2 datasets

ChIP Kelly GSE94822.TBX2.Kelly 305 bp overlap

ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 383 bp overlap

TCF3 2 datasets

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 515 bp overlap

ChIP SEM GSE85988.TCF3.SEM 483 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 126 bp overlap

ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 497 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 151 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 305 bp overlap

TRIM24 1 dataset

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 281 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 265 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 247 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 247 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 515 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 64 bp overlap

ZBED4 1 dataset

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

ZBTB7A 3 datasets

ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 65 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 106 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 72 bp overlap

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 164 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 292 bp overlap

ZKSCAN8 3 datasets

ChIP K-562 ENCSR448UKK.ZKSCAN8.K-562 364 bp overlap

ChIP K562 ENCFF387ETI 241 bp overlap

ChIP K562 ENCFF866TZL 442 bp overlap

ZNF148 1 dataset

ChIP K562 ENCFF352SDL 91 bp overlap

ZNF708 1 dataset

Motif DE_24h DE_24h-ZNF708_MA1730.2 9 bp overlap

Zfp961 1 dataset

Motif DE_24h DE_24h-Zfp961_MA2126.1 8 bp overlap