chr1:24,506,950–24,507,727

chr1 : 24,506,950 – 24,507,727

777 bp 119 TFs 6 linked genes

This 777 bp open chromatin element is linked to 6 target genes and is bound by 119 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RCAN3		4.1 kb	Proximal	Proximity
NCMAP-DT		4.6 kb	Proximal	Proximity
NIPAL3		91.4 kb	Distal	Multiome
STPG1		93.5 kb	Distal	Multiome
SRRM1		136.0 kb	Distal	Multiome
CLIC4		238.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

119 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 159 bp overlap

ChIP K562 ENCFF938UXQ 275 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 330 bp overlap

ARNT2 1 dataset

Motif DE_72h DE_72h-ARNT2_MA1464.2 8 bp overlap

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

ATF1 2 datasets

ChIP K-562 ENCSR091GVJ.ATF1.K-562 648 bp overlap

ChIP K562 ENCFF817JQF 240 bp overlap

ChIP K-562 ENCSR000BNU.ATF3.K-562 124 bp overlap

Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap

Arntl 1 dataset

Motif DE_72h DE_72h-Arntl_MA0603.2 8 bp overlap

ChIP B-cell_GERMINAL_CENTER GSE68349.BCL6.B-cell_GERMINAL_CENTER 65 bp overlap

BHLHE40 4 datasets

Motif DE_72h DE_72h-BHLHE40_MA0464.3 8 bp overlap

ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 146 bp overlap

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 219 bp overlap

ChIP K562 ENCFF923NJI 311 bp overlap

BHLHE41 1 dataset

Motif DE_72h DE_72h-BHLHE41_MA0636.1 10 bp overlap

ChIP K-562 ENCSR782WRO.BMI1.K-562 204 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 100 bp overlap

BRD4 4 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 309 bp overlap

ChIP K-562 GSE140325.BRD4.K-562 142 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD4.K-562_dilution-6-100 149 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 235 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 373 bp overlap

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 177 bp overlap

ChIP K562 ENCFF673OEZ 229 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 89 bp overlap

CREB3 1 dataset

Motif DE_72h DE_72h-CREB3_MA0638.2 12 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 192 bp overlap

ChIP K562 ENCFF403WPG 311 bp overlap

ChIP SK-N-SH GSE76815.CTCF.SK-N-SH 290 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 251 bp overlap

Creb3l2 1 dataset

Motif DE_72h DE_72h-Creb3l2_MA0608.1 9 bp overlap

ChIP K-562 GSE97661.DPF1.K-562 178 bp overlap

ChIP K562 ENCFF775HUO 294 bp overlap

ChIP K562 ENCFF886KFV 392 bp overlap

EP300 2 datasets

ChIP K-562 ENCSR000EGE.EP300.K-562 135 bp overlap

ChIP K562 ENCFF226VMS 224 bp overlap

ESR1 4 datasets

ChIP Ishikawa ENCSR000BIY.ESR1.Ishikawa 127 bp overlap

ChIP breast_tumor_Male_26 GSE104399.ESR1.breast_tumor_Male_26 288 bp overlap

ChIP breast_tumor_Male_30 GSE104399.ESR1.breast_tumor_Male_30 361 bp overlap

ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 177 bp overlap

ESRRA 1 dataset

Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap

ChIP CD4-pos GSE146787.ETS1.CD4-pos 202 bp overlap

ETV1 2 datasets

ChIP K-562 ENCSR277DMR.ETV1.K-562 194 bp overlap

ChIP K562 ENCFF389WTI 221 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 543 bp overlap

Esrrg 1 dataset

Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 777 bp overlap

ChIP DE DE-FOXA2-2 758 bp overlap

GATA1 6 datasets

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 93 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 150 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 139 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 110 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 118 bp overlap

ChIP K562 ENCFF094CMK 177 bp overlap

GATA2 2 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 277 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 115 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 777 bp overlap

ChIP DE DE-GATA4-2 777 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 200 bp overlap

ChIP foregut GSE117136.GATA4.foregut 390 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 777 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 436 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 777 bp overlap

ChIP DE DE-GATA6-2 777 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 385 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 683 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 541 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 517 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 705 bp overlap

ChIP foregut GSE117136.GATA6.foregut 364 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 257 bp overlap

Motif DE_72h DE_72h-GCM1_MA0646.2 10 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 168 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 259 bp overlap

ChIP K562 ENCFF968WBH 185 bp overlap

Motif DE_72h DE_72h-HES1_MA1099.3 8 bp overlap

HNF4A 2 datasets

Motif DE_72h DE_72h-HNF4A_MA1494.2 14 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 213 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 192 bp overlap

KDM1A 1 dataset

ChIP K-562 GSE117944.KDM1A.K-562 139 bp overlap

KMT2A 1 dataset

ChIP blood_cord GSE83671.KMT2A.blood_cord 343 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 181 bp overlap

ChIP K-562 ENCSR818DQV.MAFG.K-562 173 bp overlap

Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 165 bp overlap

MEIS2 2 datasets

ChIP K-562 ENCSR851BNE.MEIS2.K-562 307 bp overlap

ChIP K562 ENCFF320GSD 237 bp overlap

MITF 8 datasets

ChIP 501-mel GSE137522.MITF.501-mel 427 bp overlap

ChIP 501-mel GSE61965.MITF.501-mel 282 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 454 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 412 bp overlap

ChIP 501-mel_K243R GSE137522.MITF.501-mel_K243R 341 bp overlap

Motif DE_72h DE_72h-MITF_MA0620.4 10 bp overlap

ChIP K-562 ENCSR797SWM.MITF.K-562 510 bp overlap

ChIP K562 ENCFF731XJJ 457 bp overlap

Motif DE_72h DE_72h-MLX_MA0663.1 10 bp overlap

MLXIPL 1 dataset

Motif DE_72h DE_72h-MLXIPL_MA0664.2 8 bp overlap

Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap

ChIP K-562 ENCSR000EGJ.MYC.K-562 67 bp overlap

Mlxip 1 dataset

Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 242 bp overlap

NFE2 4 datasets

ChIP K-562 ENCSR552YGL.NFE2.K-562 140 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 114 bp overlap

ChIP K562 ENCFF047YKA 235 bp overlap

ChIP K562 ENCFF163BSI 69 bp overlap

NFE2L2 1 dataset

ChIP K-562 ENCSR485GKE.NFE2L2.K-562 103 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 214 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2C1 1 dataset

Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap

NR2F1 1 dataset

Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap

NR2F2 1 dataset

Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap

NR4A1 1 dataset

Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap

NR4A2 1 dataset

Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap

Nr1H2 1 dataset

Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap

PBX2 2 datasets

ChIP K-562 ENCSR263DFP.PBX2.K-562 286 bp overlap

ChIP K562 ENCFF286KMN 174 bp overlap

PDX1 3 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 163 bp overlap

ChIP islet ERP001456.PDX1.islet 192 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 347 bp overlap

ChIP breast_tumor_Male_26 GSE104399.PGR.breast_tumor_Male_26 246 bp overlap

ChIP breast_tumor_Male_26 GSE104399.PGR.breast_tumor_Male_26 253 bp overlap

ChIP breast_tumor_Male_30 GSE104399.PGR.breast_tumor_Male_30 285 bp overlap

PKNOX1 2 datasets

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 203 bp overlap

ChIP K562 ENCFF236IUS 162 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 684 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_PPARG_HYPO GSE50144.PPARG.HUVEC-C_PPARG_HYPO 123 bp overlap

PRDM4 1 dataset

ChIP HEK293 ENCFF069PHD 70 bp overlap

Ppara 1 dataset

Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap

RAD51 4 datasets

ChIP GM12878 ENCFF916JXQ 441 bp overlap

ChIP GM12878 ENCSR482TWQ.RAD51.GM12878 290 bp overlap

ChIP K-562 ENCSR524BUE.RAD51.K-562 459 bp overlap

ChIP K562 ENCFF133ELP 394 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 205 bp overlap

ChIP K562 ENCFF688UKW 411 bp overlap

RNF2 6 datasets

ChIP K-562 ENCSR138FUZ.RNF2.K-562 117 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 301 bp overlap

ChIP K-562 ENCSR076YPO.RNF2.K-562 151 bp overlap

ChIP K562 ENCFF061ATI 250 bp overlap

ChIP K562 ENCFF130DMJ 225 bp overlap

ChIP K562 ENCFF653BQJ 347 bp overlap

Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap

RREB1 1 dataset

Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap

Motif DE_72h DE_72h-RXRG_MA1556.1 14 bp overlap

SHOX2 1 dataset

ChIP K-562 ENCSR184IQF.SHOX2.K-562 177 bp overlap

SMAD2-3 2 datasets

ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 120 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 763 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 679 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 357 bp overlap

SMARCA4 1 dataset

ChIP K562 ENCFF316MCJ 485 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 494 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 631 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 274 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 154 bp overlap

ChIP K562 ENCFF059YCJ 269 bp overlap

SREBF1 2 datasets

Motif DE_72h DE_72h-SREBF1_MA0595.1 10 bp overlap

Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap

SREBF2 1 dataset

Motif DE_72h DE_72h-SREBF2_MA0828.3 10 bp overlap

STAT5B 2 datasets

ChIP CD8_H9 GSE64713.STAT5B.CD8_H9 77 bp overlap

ChIP CD8_IL2 GSE64713.STAT5B.CD8_IL2 90 bp overlap

SUZ12 3 datasets

ChIP K-562 ENCSR412CTM.SUZ12.K-562 130 bp overlap

ChIP K562 ENCFF397TBJ 445 bp overlap

ChIP K562 ENCFF397TBJ 274 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 86 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 175 bp overlap

TFE3 2 datasets

Motif DE_72h DE_72h-TFE3_MA0831.3 10 bp overlap

ChIP K562 ENCFF697ABG 277 bp overlap

Motif DE_72h DE_72h-TFEB_MA0692.2 8 bp overlap

Motif DE_72h DE_72h-TFEC_MA0871.3 8 bp overlap

ChIP K562 ENCFF728FRA 339 bp overlap

Motif DE_72h DE_72h-TP73_MA0861.2 16 bp overlap

USF1 15 datasets

Motif DE_72h DE_72h-USF1_MA0093.4 10 bp overlap

ChIP GM12878 ENCFF880HJL 257 bp overlap

ChIP GM12878 ENCSR000BGI.USF1.GM12878 158 bp overlap

ChIP H1 ENCFF090WVU 188 bp overlap

ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 149 bp overlap

ChIP HepG2 ENCFF201JKA 337 bp overlap

ChIP HepG2 ENCFF807KYJ 201 bp overlap

ChIP Ishikawa ENCFF728IEG 261 bp overlap

ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 184 bp overlap

ChIP K-562 ENCSR000BKT.USF1.K-562 332 bp overlap

ChIP K562 ENCFF202SFC 425 bp overlap

ChIP K562 ENCFF633EZB 265 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 118 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 334 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

USF2 11 datasets

Motif DE_72h DE_72h-USF2_MA0526.5 10 bp overlap

ChIP GM12878 GSE97661.USF2.GM12878 280 bp overlap

ChIP H1 ENCFF434EDF 277 bp overlap

ChIP Hep-G2 GSE97661.USF2.Hep-G2 149 bp overlap

ChIP K-562 ENCSR359NFW.USF2.K-562 303 bp overlap

ChIP K-562 ENCSR578KEN.USF2.K-562 210 bp overlap

ChIP K562 ENCFF306QPU 537 bp overlap

ChIP K562 ENCFF397QGU 265 bp overlap

ChIP K562 ENCFF495XTL 257 bp overlap

ChIP WA01 ENCSR000ECD.USF2.WA01 183 bp overlap

ChIP WTC11 ENCFF139JAW 199 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 173 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 116 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 681 bp overlap

ZKSCAN1 1 dataset

Motif DE_72h DE_72h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF143 2 datasets

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 161 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 162 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 461 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 265 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 159 bp overlap

ZNF524 1 dataset

Motif DE_72h DE_72h-ZNF524_MA2096.1 9 bp overlap

ZNF530 1 dataset

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF766 1 dataset

ChIP K562 ENCFF348LDO 367 bp overlap