chr12:113,471,448–113,471,998

chr12 : 113,471,448 – 113,471,998

550 bp 98 TFs 7 linked genes

This 550 bp open chromatin element is linked to 7 target genes and is bound by 98 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LHX5		at TSS	At TSS	Proximity
LHX5-AS1		at TSS	At TSS	Proximity
PLBD2		113.4 kb	Distal	Multiome
SLC8B1		136.8 kb	Distal	Multiome
TPCN1		250.6 kb	Distal	Multiome
RITA1		286.5 kb	Distal	Multiome
DDX54		286.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 183 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 209 bp overlap

ATF1 3 datasets

ChIP K-562 ENCSR091GVJ.ATF1.K-562 334 bp overlap

ChIP K562 ENCFF817JQF 418 bp overlap

ChIP K562 ENCFF817JQF 215 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 174 bp overlap

BRD4 9 datasets

ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 457 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 202 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 215 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 132 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 550 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 298 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 455 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 550 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 550 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 423 bp overlap

CBX2 2 datasets

ChIP K-562 ENCSR000ATU.CBX2.K-562 77 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 376 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 365 bp overlap

CBX7 2 datasets

ChIP HEK293T_PCGF2fl GSE119618.CBX7.HEK293T_PCGF2fl 550 bp overlap

ChIP HEK293T_PCGF2fl_OHT GSE119618.CBX7.HEK293T_PCGF2fl_OHT 285 bp overlap

CDK9 2 datasets

ChIP HCT-116 GSE72622.CDK9.HCT-116 155 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 134 bp overlap

CEBPB 1 dataset

ChIP WA01 ENCSR000EBV.CEBPB.WA01 130 bp overlap

CHD1 4 datasets

ChIP WA01 ENCSR000AQK.CHD1.WA01 204 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 63 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 204 bp overlap

ChIP hMSC-TERT_osteoblast GSE89179.CHD1.hMSC-TERT_osteoblast 386 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 74 bp overlap

CREB1 7 datasets

ChIP A-549 ENCSR000BRB.CREB1.A-549 130 bp overlap

ChIP GM23338 ENCFF432ZEW 151 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 288 bp overlap

ChIP H1 ENCFF955PMP 181 bp overlap

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 196 bp overlap

ChIP LNCaP GSE63034.CREB1.LNCaP 177 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 550 bp overlap

ChIP K-562 ENCSR077DKV.CREM.K-562 129 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 446 bp overlap

CTCF 3 datasets

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 54 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 145 bp overlap

ChIP neural ENCSR822CEA.CTCF.neural 278 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 358 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF896HSY 274 bp overlap

ChIP SCCOHT-1 GSE117734.DPF2.SCCOHT-1 367 bp overlap

ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 343 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 422 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 442 bp overlap

ChIP A-375 GSE116190.EGR1.A-375 100 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 232 bp overlap

EP300 1 dataset

ChIP neural ENCSR843ZUP.EP300.neural 180 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 399 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 228 bp overlap

ESR1 3 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 352 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 396 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 331 bp overlap

EZH2 31 datasets

ChIP A673 ENCFF790MVL 550 bp overlap

ChIP A673 ENCFF955JRZ 550 bp overlap

ChIP DU145_SH4 GSE135623.EZH2.DU145_SH4 264 bp overlap

ChIP DU145_SH4 GSE135623.EZH2.DU145_SH4 52 bp overlap

ChIP GM23248 ENCFF404ZHM 272 bp overlap

ChIP GM23248 ENCFF404ZHM 71 bp overlap

ChIP GM23248 ENCFF506FWX 331 bp overlap

ChIP GM23338 ENCFF613YON 391 bp overlap

ChIP GM23338 ENCFF886DXX 278 bp overlap

ChIP H1 ENCFF232NZA 550 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 277 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 209 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 476 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 550 bp overlap

ChIP Hep-G2 ENCSR000ARI.EZH2.Hep-G2 166 bp overlap

ChIP PC-9 ENCSR793USK.EZH2.PC-9 322 bp overlap

ChIP SK-N-MC ENCFF434OHW 498 bp overlap

ChIP SK-N-MC ENCFF674XUJ 498 bp overlap

ChIP T98G GSE112240.EZH2.T98G 139 bp overlap

ChIP astrocyte ENCFF365JTP 550 bp overlap

ChIP dermal-fibroblast_Preneoplastic GSE126396.EZH2.dermal-fibroblast_Preneoplastic 165 bp overlap

ChIP dermal-fibroblast_Transformed GSE126396.EZH2.dermal-fibroblast_Transformed 196 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 179 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 70 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 550 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 550 bp overlap

ChIP fibroblast of lung ENCFF479BAW 396 bp overlap

ChIP fibroblast of lung ENCFF479BAW 174 bp overlap

ChIP hESC GSE113817.EZH2.hESC 226 bp overlap

ChIP keratinocyte ENCFF070STK 220 bp overlap

ChIP prostate-cancer_plko GSE107780.EZH2.prostate-cancer_plko 189 bp overlap

EZH2_phosphoT487 1 dataset

ChIP SK-N-SH ENCSR297MUV.EZH2_phosphoT487.SK-N-SH 239 bp overlap

FOXA1 1 dataset

ChIP 22Rv1_CST_Crispr-70 GSE123618.FOXA1.22Rv1_CST_Crispr-70 74 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 346 bp overlap

FOXP2 1 dataset

ChIP PFSK1 ENCSR000BGA.FOXP2.PFSK1 96 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 204 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 114 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 381 bp overlap

HDAC2 3 datasets

ChIP A-549 ENCSR659LJJ.HDAC2.A-549 360 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 90 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap

HDAC6 1 dataset

ChIP GM12878 ENCSR933EYC.HDAC6.GM12878 266 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 550 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 341 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 452 bp overlap

HNRNPLL 3 datasets

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 249 bp overlap

ChIP K-562 GSE120104.HNRNPLL.K-562 247 bp overlap

ChIP K562 ENCFF541ZGX 398 bp overlap

INO80 2 datasets

ChIP Hep-G2 GSE97411.INO80.Hep-G2 407 bp overlap

ChIP Huh-7 GSE97411.INO80.Huh-7 512 bp overlap

JARID2 1 dataset

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 251 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 306 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 527 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 79 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 101 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 536 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 114 bp overlap

ChIP DU145_CTR GSE135623.MTF2.DU145_CTR 424 bp overlap

MXI1 2 datasets

ChIP neural ENCSR934NHU.MXI1.neural 171 bp overlap

ChIP neural cell ENCFF623HQN 384 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 162 bp overlap

MYC-DAXX 1 dataset

ChIP HEK293_GAL4-DBD GSE107348.MYC-DAXX.HEK293_GAL4-DBD 550 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 266 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 334 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 343 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 387 bp overlap

NFKB1 1 dataset

ChIP L1236 GSE63736.NFKB1.L1236 125 bp overlap

ChIP WTC11 ENCFF751ZTQ 263 bp overlap

NR2F2 1 dataset

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 445 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 395 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 342 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 375 bp overlap

ChIP GM12891 ENCSR000BJH.PAX5.GM12891 55 bp overlap

PCBP1 2 datasets

ChIP K-562 GSE120104.PCBP1.K-562 301 bp overlap

ChIP K-562 ENCSR052PTN.PCBP1.K-562 224 bp overlap

PCGF2 1 dataset

ChIP HEK293T_PCGF2fl GSE119618.PCGF2.HEK293T_PCGF2fl 425 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 213 bp overlap

POU2F1 4 datasets

ChIP 22Rv1_DHT GSE123565.POU2F1.22Rv1_DHT 162 bp overlap

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 191 bp overlap

ChIP T-47D GSE148277.POU2F1.T-47D 306 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 530 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 475 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 355 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 513 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 550 bp overlap

PRDM14 2 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 376 bp overlap

ChIP hESC GSE138674.PRDM14.hESC 59 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 356 bp overlap

RAD21 1 dataset

ChIP neural ENCSR198ZYJ.RAD21.neural 324 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 463 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 389 bp overlap

ChIP LNCaP GSE119385.REST.LNCaP 380 bp overlap

RFX1 4 datasets

ChIP K-562 ENCSR968GIB.RFX1.K-562 245 bp overlap

ChIP K-562 ENCSR041AXL.RFX1.K-562 209 bp overlap

ChIP K562 ENCFF809XVG 149 bp overlap

ChIP K562 ENCFF809XVG 79 bp overlap

RNF2 11 datasets

ChIP H1 ENCFF239FFS 165 bp overlap

ChIP HEK293T_PCGF1356fl GSE119618.RNF2.HEK293T_PCGF1356fl 248 bp overlap

ChIP HEK293T_PCGF1356fl_OHT GSE119618.RNF2.HEK293T_PCGF1356fl_OHT 424 bp overlap

ChIP HEK293T_PCGF135fl GSE119618.RNF2.HEK293T_PCGF135fl 209 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.RNF2.HEK293T_PCGF135fl_OHT 295 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.RNF2.HEK293T_PCGF2fl 233 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.RNF2.HEK293T_PCGF2fl 252 bp overlap

ChIP HUES-64 GSE104059.RNF2.HUES-64 143 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.RNF2.SYO-1_shRING1A-B 399 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 91 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 249 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 401 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 550 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 263 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 238 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 243 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 104 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 243 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 343 bp overlap

SMARCA4 3 datasets

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 220 bp overlap

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 357 bp overlap

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 397 bp overlap

SMARCC1 3 datasets

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 295 bp overlap

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 174 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 247 bp overlap

ChIP neural ENCSR404BPV.SMC3.neural 62 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 450 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 399 bp overlap

SS18 4 datasets

ChIP Aska-SS_BAF47KO1 GSE108025.SS18.Aska-SS_BAF47KO1 171 bp overlap

ChIP SYO-1 GSE108025.SS18.SYO-1 550 bp overlap

ChIP SYO-1_shCt GSE139053.SS18.SYO-1_shCt 550 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 425 bp overlap

STAT1 1 dataset

ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 179 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 418 bp overlap

SUZ12 21 datasets

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 252 bp overlap

ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 122 bp overlap

ChIP H1 ENCFF881NFR 550 bp overlap

ChIP HEK293T_PCGF1352fl GSE119618.SUZ12.HEK293T_PCGF1352fl 254 bp overlap

ChIP HEK293T_PCGF1352fl_OHT GSE119618.SUZ12.HEK293T_PCGF1352fl_OHT 274 bp overlap

ChIP HEK293T_PCGF1356fl GSE119618.SUZ12.HEK293T_PCGF1356fl 550 bp overlap

ChIP HEK293T_PCGF1356fl_OHT GSE119618.SUZ12.HEK293T_PCGF1356fl_OHT 550 bp overlap

ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 550 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.SUZ12.HEK293T_PCGF135fl_OHT 550 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 550 bp overlap

ChIP HEK293T_PCGF2fl_OHT GSE119618.SUZ12.HEK293T_PCGF2fl_OHT 550 bp overlap

ChIP K-562 ENCSR000AUC.SUZ12.K-562 99 bp overlap

ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 77 bp overlap

ChIP NCCIT GSE71675.SUZ12.NCCIT 106 bp overlap

ChIP NCCIT GSE71675.SUZ12.NCCIT 281 bp overlap

ChIP NT2/D1 ENCFF574SXS 208 bp overlap

ChIP NT2/D1 ENCFF574SXS 209 bp overlap

ChIP SYO-1_shCt GSE139053.SUZ12.SYO-1_shCt 427 bp overlap

ChIP SYO-1_shRING1A-B GSE139053.SUZ12.SYO-1_shRING1A-B 336 bp overlap

ChIP WA01 ENCSR000ATS.SUZ12.WA01 550 bp overlap

ChIP WA01 ENCSR000EUQ.SUZ12.WA01 56 bp overlap

TAF1 2 datasets

ChIP neural cell ENCFF468SPD 310 bp overlap

ChIP neural cell ENCFF468SPD 430 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 134 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 455 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 395 bp overlap

TRIM28 2 datasets

ChIP HCT-116 GSE72622.TRIM28.HCT-116 52 bp overlap

ChIP HCT-116 GSE72622.TRIM28.HCT-116 239 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 507 bp overlap

ChIP LNCaP_Tg GSE121880.XBP1.LNCaP_Tg 234 bp overlap

ZNF555 1 dataset

ChIP HEK293T GSE78099.ZNF555.HEK293T 390 bp overlap

ZNF800 1 dataset

ChIP Hep-G2 ENCSR701WPG.ZNF800.Hep-G2 187 bp overlap