Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within acinar cell differentiation and endocrine pancreas development. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for ZNF800. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF800 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF800, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr7:127,251,385–127,254,562 | 139.7 kb | Distal (>10kb) Multiome | 644 | |
| chr7:127,347,511–127,348,270 | 44.8 kb | Distal (>10kb) Multiome | 487 | |
| chr7:127,391,433–127,393,629 | 17 bp | At TSS Multiome | 929 | |
| chr7:127,395,033–127,395,800 | 2.3 kb | Proximal (<10kb) | 140 | |
| chr7:127,396,228–127,396,403 | 3.5 kb | Proximal (<10kb) | 88 | |
| chr7:127,584,951–127,586,129 | 192.9 kb | Distal (>10kb) Multiome | 808 | |
| chr7:127,587,636–127,589,370 | 195.6 kb | Distal (>10kb) Multiome | 807 | |
| chr7:127,619,493–127,621,269 | 227.6 kb | Distal (>10kb) Multiome | 302 | |
| chr7:127,628,938–127,629,789 | 236.8 kb | Distal (>10kb) Multiome | 216 | |
| chr7:127,650,994–127,652,678 | 259.2 kb | Distal (>10kb) Multiome | 1039 | |
| chr7:127,665,882–127,666,444 | 273.4 kb | Distal (>10kb) Multiome | 161 |
Genomic view of the ZNF800 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.