chr11:316,978–318,064

chr11 : 316,978 – 318,064

1,086 bp 100 TFs 19 linked genes

This 1.1 kb open chromatin element is linked to 19 target genes and is bound by 100 transcription factors.

Linked Genes

19 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000251661		588 bp	At TSS	Proximity
IFITM3		2.8 kb	Proximal	Proximity
IFITM1		2.9 kb	Proximal	Proximity
ENSG00000254910		5.8 kb	Proximal	Proximity
IFITM2		8.9 kb	Proximal	Proximity
PGGHG		28.0 kb	Distal	Multiome
B4GALNT4		52.3 kb	Distal	Multiome+HiCAR
PSMD13		80.2 kb	Distal	Multiome
SIRT3		80.8 kb	Distal	Multiome
SIGIRR		100.2 kb	Distal	Multiome
RIC8A		109.5 kb	Distal	Multiome
BET1L		109.8 kb	Distal	Multiome
PTDSS2		131.1 kb	Distal	Multiome
RNH1		190.0 kb	Distal	Multiome
HRAS		218.4 kb	Distal	Multiome
LMNTD2-AS1		240.4 kb	Distal	Multiome
RASSF7		243.8 kb	Distal	Multiome
MIR210HG		251.3 kb	Distal	Multiome
PHRF1		259.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

100 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 242 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 332 bp overlap

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 140 bp overlap

BACH1 1 dataset

Motif DE_36h DE_36h-BACH1_MA1633.2 9 bp overlap

Motif DE_36h DE_36h-BCL6_MA0463.3 13 bp overlap

BCOR 3 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 178 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 272 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 181 bp overlap

BRD2 2 datasets

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 202 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD2.K-562_DMSO-IFNG 243 bp overlap

BRD3 4 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 396 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 154 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 246 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD3.K-562_iBET-BD1-IFNG 225 bp overlap

BRD4 10 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 191 bp overlap

ChIP CD4_Th1_DMSO GSE62482.BRD4.CD4_Th1_DMSO 111 bp overlap

ChIP HAP1 GSE108387.BRD4.HAP1 587 bp overlap

ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 337 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 286 bp overlap

ChIP K-562_iBET GSE138084.BRD4.K-562_iBET 234 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 347 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 170 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 272 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 181 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 199 bp overlap

CTCF 13 datasets

ChIP GM04648 GSE148179.CTCF.GM04648 165 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 281 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 182 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 463 bp overlap

ChIP adrenal-gland ENCSR770IWO.CTCF.adrenal-gland 296 bp overlap

ChIP aorta_thoracic ENCSR668BTN.CTCF.aorta_thoracic 256 bp overlap

ChIP breast epithelium ENCFF080KNR 437 bp overlap

ChIP breast_epithelium ENCSR661NXJ.CTCF.breast_epithelium 370 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 444 bp overlap

ChIP nerve_tibial ENCSR434XLP.CTCF.nerve_tibial 259 bp overlap

ChIP spleen ENCSR225YGX.CTCF.spleen 405 bp overlap

ChIP spleen ENCSR343RJH.CTCF.spleen 295 bp overlap

ChIP spleen ENCSR601FEB.CTCF.spleen 248 bp overlap

ChIP K-562 ENCSR000EWL.E2F4.K-562 141 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 140 bp overlap

EP300 1 dataset

ChIP tibial nerve ENCFF346AYA 183 bp overlap

ChIP K562 ENCFF626IQJ 337 bp overlap

EZH2 7 datasets

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 295 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 270 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 188 bp overlap

ChIP hepatocyte ENCFF118DKH 357 bp overlap

ChIP hepatocyte ENCFF552DZB 251 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 341 bp overlap

ChIP neural progenitor cell ENCFF472NFV 800 bp overlap

EZH2_phosphoT487 2 datasets

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 203 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 388 bp overlap

FOSL1::JUN 1 dataset

Motif DE_36h DE_36h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 1 dataset

Motif DE_36h DE_36h-FOSL1JUNB_MA1137.2 9 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 432 bp overlap

ChIP DE DE-FOXA2-2 456 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 762 bp overlap

ChIP DE DE-GATA4-2 910 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 622 bp overlap

ChIP DE DE-GATA6-2 938 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 895 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 925 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 960 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 556 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 978 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 922 bp overlap

GMEB1 2 datasets

ChIP K562 ENCFF705LHX 601 bp overlap

ChIP K562 ENCFF705LHX 487 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR387UWP.HDAC1.K-562 446 bp overlap

HNF4A 2 datasets

Motif DE_36h DE_36h-HNF4A_MA0114.5 9 bp overlap

Motif DE_36h DE_36h-HNF4A_MA1494.2 14 bp overlap

HNF4G 1 dataset

Motif DE_36h DE_36h-HNF4G_MA0484.3 9 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 152 bp overlap

HNRNPK 1 dataset

ChIP primary-keratinocyte GSE122327.HNRNPK.primary-keratinocyte 509 bp overlap

IKZF1 5 datasets

ChIP GM12878 ENCFF753XDO 450 bp overlap

ChIP GM12878 ENCFF824TGK 618 bp overlap

ChIP K-562 ENCSR395HWC.IKZF1.K-562 947 bp overlap

ChIP K562 ENCFF348IBL 240 bp overlap

ChIP K562 ENCFF771OHZ 471 bp overlap

IKZF2 4 datasets

ChIP GM12878 ENCFF238LYK 478 bp overlap

ChIP GM12878 ENCFF918AID 384 bp overlap

ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 243 bp overlap

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 266 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 401 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 531 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 397 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 1054 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 647 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 316 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 481 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 330 bp overlap

ChIP T-cell GSE136853.JUN.T-cell 235 bp overlap

KDM1A 2 datasets

ChIP K562 ENCFF133OLU 442 bp overlap

ChIP K562 ENCFF133OLU 461 bp overlap

KLF4 2 datasets

ChIP HAP1 GSE130417.KLF4.HAP1 268 bp overlap

ChIP PDAC GSE64557.KLF4.PDAC 88 bp overlap

KMT2A 1 dataset

ChIP IMS-M2_DMSO GSE129636.KMT2A.IMS-M2_DMSO 379 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 558 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 275 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 231 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 289 bp overlap

MITF 2 datasets

ChIP K562 ENCFF731XJJ 425 bp overlap

ChIP K562 ENCFF731XJJ 284 bp overlap

MLLT1 4 datasets

ChIP GM12878 ENCFF995GXC 242 bp overlap

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 286 bp overlap

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 402 bp overlap

ChIP K-562 ENCSR107GRP.MLLT1.K-562 411 bp overlap

MTA2 2 datasets

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 240 bp overlap

ChIP K-562 ENCSR411UYA.MTA2.K-562 241 bp overlap

ChIP P493-6_Dpy30-shRNA GSE101853.MYC.P493-6_Dpy30-shRNA 161 bp overlap

NANOG 3 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 309 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 409 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 358 bp overlap

NCOA1 1 dataset

ChIP K562 ENCFF395XLS 323 bp overlap

NEUROD1 6 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 403 bp overlap

ChIP D283-Med GSE92582.NEUROD1.D283-Med 311 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 323 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 185 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 219 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 292 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 218 bp overlap

NFRKB 1 dataset

ChIP K-562 ENCSR657EOF.NFRKB.K-562 272 bp overlap

ChIP K562 ENCFF268WFF 317 bp overlap

PATZ1 1 dataset

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 165 bp overlap

ChIP K-562 ENCSR000BQY.PML.K-562 185 bp overlap

POLR2A 21 datasets

ChIP GM12878 ENCFF631ERR 458 bp overlap

ChIP GM12878 ENCFF631ERR 491 bp overlap

ChIP GM12878 ENCFF631ERR 391 bp overlap

ChIP GM12891 ENCFF012SUT 292 bp overlap

ChIP GM12892 ENCFF506PGQ 477 bp overlap

ChIP GM15510 ENCFF880HVJ 437 bp overlap

ChIP GM19193 ENCFF599VTO 226 bp overlap

ChIP K562 ENCFF215CWW 625 bp overlap

ChIP K562 ENCFF215CWW 625 bp overlap

ChIP K562 ENCFF419GHN 573 bp overlap

ChIP K562 ENCFF836GHX 78 bp overlap

ChIP body of pancreas ENCFF675RCN 625 bp overlap

ChIP breast epithelium ENCFF045XXN 465 bp overlap

ChIP esophagus muscularis mucosa ENCFF432ZCY 465 bp overlap

ChIP gastroesophageal sphincter ENCFF070PCA 341 bp overlap

ChIP right lobe of liver ENCFF026NCK 130 bp overlap

ChIP sigmoid colon ENCFF748YVT 445 bp overlap

ChIP spleen ENCFF044PYR 386 bp overlap

ChIP spleen ENCFF446ZGT 375 bp overlap

ChIP transverse colon ENCFF098HBD 465 bp overlap

ChIP vagina ENCFF384GAB 168 bp overlap

POLR2H 1 dataset

ChIP K562 ENCFF377NHG 841 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 1023 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 637 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 312 bp overlap

PPARA::RXRA 1 dataset

Motif DE_36h DE_36h-PPARARXRA_MA1148.2 17 bp overlap

PRDM10 1 dataset

ChIP K-562 ENCSR120MPG.PRDM10.K-562 287 bp overlap

PTBP1 1 dataset

ChIP K-562 GSE120104.PTBP1.K-562 165 bp overlap

Prdm14 1 dataset

Motif DE_36h DE_36h-Prdm14_MA1998.2 8 bp overlap

RAD21 1 dataset

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 276 bp overlap

RAD51 1 dataset

ChIP GM12878 ENCSR482TWQ.RAD51.GM12878 224 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 357 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 396 bp overlap

RBM39 1 dataset

ChIP K-562 ENCSR764OXF.RBM39.K-562 182 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 273 bp overlap

ChIP K-562 ENCSR137ZMQ.REST.K-562 211 bp overlap

SIN3A 2 datasets

ChIP K-562 ENCSR920BLG.SIN3A.K-562 139 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 109 bp overlap

Motif DE_36h DE_36h-SIX1_MA1118.2 9 bp overlap

Motif DE_36h DE_36h-SIX2_MA1119.2 11 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 721 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 957 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 835 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 870 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 921 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1009 bp overlap

SMAD5 1 dataset

ChIP K-562 ENCSR000FCD.SMAD5.K-562 335 bp overlap

SMARCA4 2 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 318 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 308 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 292 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 229 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 278 bp overlap

ChIP DE_D1 S10-DE-d1-BAF155-exp1 272 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 382 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 531 bp overlap

SOX15 1 dataset

Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 372 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 259 bp overlap

STAT3 1 dataset

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 152 bp overlap

SUPT5H 3 datasets

ChIP HeLa GSE125534.SUPT5H.HeLa 293 bp overlap

ChIP K562 ENCFF902PAW 391 bp overlap

ChIP K562 ENCFF902PAW 394 bp overlap

Motif DE_36h DE_36h-Six4_MA2001.2 7 bp overlap

Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap

Stat6 1 dataset

Motif DE_36h DE_36h-Stat6_MA0520.2 10 bp overlap

ChIP GM12878 ENCSR000BQT.TCF3.GM12878 117 bp overlap

TCF7L2 1 dataset

Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 239 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 435 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 458 bp overlap

TP53 2 datasets

ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 882 bp overlap

ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 193 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 198 bp overlap

ChIP LCLGM10861_CALCITRIOL GSE22484.VDR.LCLGM10861_CALCITRIOL 130 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 146 bp overlap

ZBED1 1 dataset

ChIP K-562 ENCSR286PCG.ZBED1.K-562 169 bp overlap

ZBTB2 1 dataset

ChIP K-562 ENCSR230PTV.ZBTB2.K-562 287 bp overlap

ZBTB40 4 datasets

ChIP GM12878 ENCFF346DYM 62 bp overlap

ChIP GM12878 ENCFF346DYM 305 bp overlap

ChIP GM12878 ENCSR189YYK.ZBTB40.GM12878 154 bp overlap

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 507 bp overlap

ZBTB7A 2 datasets

ChIP K-562 GSE103445.ZBTB7A.K-562 187 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 362 bp overlap

ChIP K-562 ENCSR322CFO.ZEB2.K-562 320 bp overlap

ZMAT4 1 dataset

ChIP WTC11 ENCFF608UXZ 240 bp overlap

ZNF549 1 dataset

Motif DE_36h DE_36h-ZNF549_MA1728.2 8 bp overlap

ZNF740 1 dataset

ChIP K562 ENCFF505NFV 343 bp overlap

ZSCAN29 1 dataset

ChIP K-562 ENCSR175SZH.ZSCAN29.K-562 325 bp overlap