chr9:19,446,288–19,446,838

chr9 : 19,446,288 – 19,446,838

550 bp 110 TFs 5 linked genes

This 550 bp open chromatin element is linked to 5 target genes and is bound by 110 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000260912		6.4 kb	Proximal	Proximity
ACER2		37.7 kb	Distal	Multiome
RPS6		66.4 kb	Distal	Multiome+HiCAR
DENND4C		215.9 kb	Distal	Multiome
PLIN2		319.2 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

110 transcription factors

ASCL1 4 datasets

ChIP NCI-H128 GSE69394.ASCL1.NCI-H128 187 bp overlap

ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 124 bp overlap

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 156 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 205 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 434 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 550 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 450 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 303 bp overlap

Arid3a 1 dataset

Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap

BCL11A 2 datasets

ChIP H1 ENCFF836SSR 177 bp overlap

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 172 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 316 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 491 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD2.MV4-11_IBET151_500nM 147 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD3.MV4-11_IBET151_500nM 112 bp overlap

ChIP HUVEC-C GSE60171.BRD4.HUVEC-C 172 bp overlap

CHD2 2 datasets

ChIP H1 ENCFF991MKH 276 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 291 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 155 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 550 bp overlap

DMRTA2 1 dataset

Motif ES_0h ES_0h-DMRTA2_MA1478.2 6 bp overlap

Dmrt1 1 dataset

Motif ES_0h ES_0h-Dmrt1_MA1603.2 9 bp overlap

ChIP ProEs GSE59087.EED.ProEs 152 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 210 bp overlap

ChIP hESC GSE17917.EP300.hESC 398 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 261 bp overlap

ETV2::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 65 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 189 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 366 bp overlap

GTF3C2 2 datasets

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

ChIP H9 GSE94418.GTF3C2.H9 171 bp overlap

HDAC2 3 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 148 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 194 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 137 bp overlap

Hand1 1 dataset

Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap

Motif ES_0h ES_0h-IRF3_MA1418.2 17 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 298 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 458 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 423 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 146 bp overlap

KDM1A 2 datasets

ChIP H1 ENCFF696SGD 500 bp overlap

ChIP H1 ENCFF696SGD 291 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 144 bp overlap

KLF10 2 datasets

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

KLF12 2 datasets

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

Motif ES_0h ES_0h-KLF12_MA0742.2 9 bp overlap

KLF14 2 datasets

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap

KLF16 2 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

KLF5 2 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 211 bp overlap

ChIP WTC11 ENCFF223QFY 516 bp overlap

ChIP WTC11 ENCFF223QFY 411 bp overlap

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap

MEIS1 1 dataset

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

NANOG 6 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 550 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 159 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 165 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 325 bp overlap

ChIP hESC GSE18292.NANOG.hESC 180 bp overlap

NR2C2 2 datasets

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

Motif ES_0h ES_0h-NR2C2_MA0504.2 14 bp overlap

Nr2F6 1 dataset

Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap

PATZ1 2 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PAX3-FOXO1 1 dataset

ChIP Hs-352-Sk GSE83725.PAX3-FOXO1.Hs-352-Sk 198 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 405 bp overlap

PHOX2A 1 dataset

Motif ES_0h ES_0h-PHOX2A_MA0713.1 11 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU4F1 1 dataset

Motif ES_0h ES_0h-POU4F1_MA0790.2 12 bp overlap

POU4F3 1 dataset

Motif ES_0h ES_0h-POU4F3_MA0791.2 12 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 258 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 519 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 295 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 280 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 323 bp overlap

PPARA::RXRA 1 dataset

Motif ES_0h ES_0h-PPARARXRA_MA1148.2 17 bp overlap

PRDM9 2 datasets

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap

PROP1 1 dataset

Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

Prdm5 1 dataset

Motif ES_0h ES_0h-Prdm5_MA1999.2 11 bp overlap

RBBP5 3 datasets

ChIP H1 ENCFF905HFL 465 bp overlap

ChIP H1 ENCFF905HFL 304 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 550 bp overlap

Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap

Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 204 bp overlap

SIN3A 2 datasets

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 271 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 172 bp overlap

Motif ES_0h ES_0h-SIX1_MA1118.2 9 bp overlap

Motif ES_0h ES_0h-SIX2_MA1119.2 11 bp overlap

ChIP WTC11 ENCFF891HYW 95 bp overlap

SIX5 2 datasets

ChIP H1 ENCFF942SOJ 237 bp overlap

ChIP WA01 ENCSR000BIQ.SIX5.WA01 151 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 337 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 402 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 260 bp overlap

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 275 bp overlap

SMARCA4 2 datasets

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 215 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 325 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 288 bp overlap

SMARCC1 3 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 501 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 389 bp overlap

SOX10 1 dataset

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX11 1 dataset

ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 68 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 163 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 349 bp overlap

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

Motif ES_0h ES_0h-SP1_MA0079.5 9 bp overlap

ChIP H1 ENCFF263FUH 303 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 300 bp overlap

ChIP WTC11 ENCFF688PEU 420 bp overlap

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

Motif ES_0h ES_0h-SP2_MA0516.3 9 bp overlap

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

ChIP H1 ENCFF473YOB 515 bp overlap

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 429 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 220 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap

ChIP H1 ENCFF859IIO 377 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 274 bp overlap

ChIP hESC GSE122298.TBP.hESC 287 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 128 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 246 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 235 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 386 bp overlap

ChIP NPC GSE154479.TCF3.NPC 550 bp overlap

TCF7L1 1 dataset

Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 135 bp overlap

TP53 2 datasets

ChIP WTC11 ENCFF359JCU 426 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 344 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 486 bp overlap

USF1 2 datasets

ChIP WA01 ENCSR000BIU.USF1.WA01 193 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 206 bp overlap

ZFP14 2 datasets

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

Motif ES_0h ES_0h-ZFP14_MA1972.1 15 bp overlap

ZKSCAN5 2 datasets

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCFF631OSW 357 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 233 bp overlap

ZNF148 2 datasets

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF184 2 datasets

Motif ES_0h ES_0h-ZNF184_MA2120.1 13 bp overlap

ChIP WTC11 ENCFF352POG 411 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 256 bp overlap

ZNF257 2 datasets

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap

ZNF281 3 datasets

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ChIP WTC11 ENCFF551GAV 320 bp overlap

ZNF282 2 datasets

Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap

Motif ES_0h ES_0h-ZNF282_MA1154.2 15 bp overlap

ZNF317 1 dataset

Motif ES_0h ES_0h-ZNF317_MA1593.2 8 bp overlap

ZNF354A 1 dataset

Motif ES_0h ES_0h-ZNF354A_MA1978.2 20 bp overlap

ZNF418 1 dataset

Motif ES_0h ES_0h-ZNF418_MA1980.1 15 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 344 bp overlap

ZNF816 2 datasets

Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap

Motif ES_0h ES_0h-ZNF816_MA1719.2 15 bp overlap

ZSCAN4 1 dataset

Motif ES_0h ES_0h-ZSCAN4_MA1155.1 15 bp overlap