chr8:22,176,636–22,177,193

chr8 : 22,176,636 – 22,177,193

557 bp 91 TFs 8 linked genes

This 557 bp open chromatin element is linked to 8 target genes and is bound by 91 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
BMP1		11.8 kb	Distal	Multiome
REEP4		35.1 kb	Distal	Multiome
POLR3D		68.1 kb	Distal	Multiome
FHIP2B		87.8 kb	Distal	Multiome
PIWIL2		98.3 kb	Distal	Multiome
SLC39A14		190.3 kb	Distal	Multiome
XPO7		257.3 kb	Distal	Multiome
PPP3CC		264.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

91 transcription factors

AGO1 4 datasets

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 61 bp overlap

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 198 bp overlap

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 194 bp overlap

ChIP K-562 ENCSR641BSL.AGO1.K-562 150 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 143 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 171 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 138 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 263 bp overlap

ARNTL 1 dataset

ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 178 bp overlap

ASH2L 2 datasets

ChIP WA01 ENCSR850KIP.ASH2L.WA01 110 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 247 bp overlap

BACH1 1 dataset

ChIP WA01 ENCSR000EBQ.BACH1.WA01 136 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 236 bp overlap

BRD4 10 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 185 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 192 bp overlap

ChIP HCT-15 GSE73319.BRD4.HCT-15 85 bp overlap

ChIP LNCaP-clone-FGC_DHT-Enzalutamide GSE118247.BRD4.LNCaP-clone-FGC_DHT-Enzalutamide 116 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 499 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 214 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 391 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 74 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 263 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 193 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 171 bp overlap

ChIP T-47D_ETOH_5 GSE62428.CHD8.T-47D_ETOH_5 115 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 140 bp overlap

CREBBP_M768 1 dataset

ChIP NCI-H3396_E2 GSE32349.CREBBP_M768.NCI-H3396_E2 96 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 237 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 237 bp overlap

ChIP BLaER1 ENCFF335XTP 121 bp overlap

DNMT3B 2 datasets

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 128 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 154 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP HEK293 ENCFF336LFH 75 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 151 bp overlap

ChIP PDAC GSE64557.ELF3.PDAC 122 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 355 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 178 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 54 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 190 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 149 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 213 bp overlap

ESR1 4 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 291 bp overlap

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 62 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 62 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 222 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 161 bp overlap

FLI1 4 datasets

ChIP ME-1 GSE46044.FLI1.ME-1 150 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 154 bp overlap

ChIP UAE GSE23730.FLI1.UAE 246 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 447 bp overlap

GABPA 2 datasets

ChIP K-562 ENCSR000BLO.GABPA.K-562 133 bp overlap

ChIP MCF-7 GSE72082.GABPA.MCF-7 72 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 202 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 236 bp overlap

GLIS2 2 datasets

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 309 bp overlap

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 557 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 557 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 121 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 51 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 225 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 447 bp overlap

ChIP HEK293 ENCSR803GYT.HIC1.HEK293 103 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 173 bp overlap

HMGN3 1 dataset

ChIP K-562 ENCSR000DOB.HMGN3.K-562 180 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 166 bp overlap

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 165 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 95 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 154 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 125 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 120 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 490 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 212 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 425 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 374 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 188 bp overlap

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 320 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 163 bp overlap

ChIP H1 ENCFF914VQY 101 bp overlap

ChIP Ishikawa ENCFF064TDQ 169 bp overlap

ChIP Ishikawa ENCSR000BTY.MAX.Ishikawa 79 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 207 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 214 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 255 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 106 bp overlap

NFIB 2 datasets

ChIP MCF-7 ENCFF925CGH 74 bp overlap

ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 60 bp overlap

NFIC 4 datasets

ChIP Ishikawa ENCFF029AAD 80 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 82 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 181 bp overlap

ChIP K562 ENCFF167YID 104 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 219 bp overlap

NR3C1 4 datasets

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 118 bp overlap

ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 212 bp overlap

ChIP BEAS-2B_shNR3C1_TNF_IA1 GSE125623.NR3C1.BEAS-2B_shNR3C1_TNF_IA1 112 bp overlap

ChIP breast_tumor_Male_15 GSE104399.NR3C1.breast_tumor_Male_15 104 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 205 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 228 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 155 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 321 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 367 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 316 bp overlap

POLR2A 3 datasets

ChIP spleen ENCFF044PYR 96 bp overlap

ChIP spleen ENCFF446ZGT 147 bp overlap

ChIP spleen ENCFF706IUS 163 bp overlap

POU2F1 2 datasets

ChIP T-47D GSE148277.POU2F1.T-47D 138 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 101 bp overlap

POU5F1 2 datasets

ChIP SKM-1 GSE93706.POU5F1.SKM-1 251 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 259 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 557 bp overlap

RAD21 2 datasets

ChIP HCT-116 GSE131606.RAD21.HCT-116 107 bp overlap

ChIP HCT-116 GSE131606.RAD21.HCT-116 187 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 230 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 137 bp overlap

RBFOX2 5 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 158 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 181 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 262 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 211 bp overlap

ChIP K562 ENCFF967GRF 470 bp overlap

ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 116 bp overlap

RFX1 2 datasets

ChIP K-562 ENCSR041AXL.RFX1.K-562 83 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 54 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 497 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 557 bp overlap

RUNX1 2 datasets

ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 98 bp overlap

ChIP epididymis_HEE GSE109061.RUNX1.epididymis_HEE 186 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 224 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

ChIP WTC11 ENCFF688PEU 333 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 158 bp overlap

SREBF2 1 dataset

ChIP HeLa-S3 ENCSR611WZO.SREBF2.HeLa-S3 96 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 477 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 390 bp overlap

STAT1 1 dataset

ChIP NCI-H358 GSE79707.STAT1.NCI-H358 188 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 295 bp overlap

ChIP H1 ENCFF478SZO 239 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 155 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 557 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 557 bp overlap

TP63 3 datasets

ChIP keratinocyte GSE33571.TP63.keratinocyte 353 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 230 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 90 bp overlap

TRIM24 1 dataset

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 382 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 429 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 139 bp overlap

VEZF1 2 datasets

ChIP K-562 ENCSR189YMA.VEZF1.K-562 240 bp overlap

ChIP K562 ENCFF053XDV 557 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 467 bp overlap

ChIP H1 ENCFF524BTL 232 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 119 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 185 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 283 bp overlap

ChIP K562 ENCFF875HLX 237 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 99 bp overlap

ZFHX2 2 datasets

ChIP HEK293 ENCFF167TUA 278 bp overlap

ChIP HEK293 ENCFF167TUA 74 bp overlap

ZMYND11 1 dataset

ChIP HeLa GSE51672.ZMYND11.HeLa 199 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 242 bp overlap

ZNF316 2 datasets

ChIP K-562 ENCSR200JYP.ZNF316.K-562 214 bp overlap

ChIP K562 ENCFF281INV 288 bp overlap

ZNF317 1 dataset

ChIP WTC11 ENCFF537KXI 245 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 218 bp overlap