chr2:46,704,551–46,705,027

chr2 : 46,704,551 – 46,705,027

476 bp 109 TFs 8 linked genes

This 476 bp open chromatin element is linked to 8 target genes and is bound by 109 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SOCS5		5.3 kb	Proximal	Proximity
LINC01118		5.6 kb	Proximal	Proximity
PIGF		87.8 kb	Distal	Multiome
CRIPT		88.4 kb	Distal	Multiome
RHOQ		162.1 kb	Distal	Multiome
ATP6V1E2		162.2 kb	Distal	Multiome
MCFD2		211.0 kb	Distal	Multiome
TTC7A		211.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

109 transcription factors

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 476 bp overlap

ChIP H1 ENCFF399KAM 476 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 476 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 317 bp overlap

ATOH7 1 dataset

Motif DE_12h DE_12h-ATOH7_MA1468.1 10 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA0461.3 8 bp overlap

BHLHA15 1 dataset

Motif DE_12h DE_12h-BHLHA15_MA0607.2 10 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA0818.2 10 bp overlap

BHLHE23 1 dataset

Motif DE_12h DE_12h-BHLHE23_MA0817.2 10 bp overlap

BRD4 2 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 143 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

CASZ1 1 dataset

ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 109 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 59 bp overlap

CHD7 4 datasets

ChIP H1 ENCFF126NLU 455 bp overlap

ChIP H1 ENCFF126NLU 410 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 115 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 163 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 134 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 145 bp overlap

CTCF 2 datasets

Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap

ChIP breast_epithelium ENCSR697YIN.CTCF.breast_epithelium 195 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF460KDD 207 bp overlap

ChIP ProEs GSE59087.EED.ProEs 200 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 229 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 336 bp overlap

ChIP DE DE-FOXA2-2 370 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 380 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF939VKA 237 bp overlap

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HOXB4 1 dataset

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Motif DE_12h DE_12h-Hic1_MA0739.2 8 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 389 bp overlap

ChIP A549 ENCFF251BPG 201 bp overlap

JUND 2 datasets

ChIP H1 ENCFF468JZD 231 bp overlap

ChIP WA01 ENCSR000EBZ.JUND.WA01 137 bp overlap

KLF17 1 dataset

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

ChIP islet ERP004003.MAFB.islet 210 bp overlap

MAFK 2 datasets

ChIP H1 ENCFF854XWE 285 bp overlap

ChIP WA01 ENCSR000EBS.MAFK.WA01 193 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 259 bp overlap

MAX::MYC 1 dataset

Motif DE_12h DE_12h-MAXMYC_MA0059.2 10 bp overlap

MEF2A 1 dataset

Motif DE_12h DE_12h-MEF2A_MA0052.5 10 bp overlap

MEF2B 1 dataset

Motif DE_12h DE_12h-MEF2B_MA0660.1 12 bp overlap

MEF2C 1 dataset

Motif DE_12h DE_12h-MEF2C_MA0497.2 11 bp overlap

MEF2D 1 dataset

Motif DE_12h DE_12h-MEF2D_MA0773.1 12 bp overlap

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 148 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 239 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 476 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 446 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 153 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 476 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 476 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 301 bp overlap

ChIP hESC GSE20650.NANOG.hESC 187 bp overlap

ChIP hESC GSE18292.NANOG.hESC 156 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_G GSE118494.NCAPH2.IMR-90_FLAG_G 423 bp overlap

NEUROG1 1 dataset

Motif DE_12h DE_12h-NEUROG1_MA0623.2 10 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA0669.1 10 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NIPBL 4 datasets

ChIP hESC GSE64758.NIPBL.hESC 281 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 202 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 237 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 319 bp overlap

NKX6-1 1 dataset

Motif DE_12h DE_12h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_12h DE_12h-NKX6-3_MA1530.2 8 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

OLIG1 1 dataset

Motif DE_12h DE_12h-OLIG1_MA0826.1 10 bp overlap

OLIG2 1 dataset

Motif DE_12h DE_12h-OLIG2_MA0678.1 10 bp overlap

OLIG3 1 dataset

Motif DE_12h DE_12h-OLIG3_MA0827.1 10 bp overlap

ChIP AB32 GSE31129.PGR.AB32 118 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 449 bp overlap

ChIP H1 ENCFF566JSR 186 bp overlap

ChIP H1 ENCFF833NJP 84 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 136 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 9 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 287 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 476 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 237 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 245 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 421 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 333 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 209 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

RAD21 2 datasets

ChIP H1 ENCFF698EWO 231 bp overlap

ChIP WA09 GSE105028.RAD21.WA09 184 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 93 bp overlap

Motif DE_12h DE_12h-REL_MA0101.1 10 bp overlap

RELA 2 datasets

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

ChIP LNCaP_SICTR_TNFA GSE83860.RELA.LNCaP_SICTR_TNFA 150 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 204 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap

ChIP WTC11 ENCFF815YYQ 357 bp overlap

SMARCA4 3 datasets

ChIP TTC-1240_R377H GSE124903.SMARCA4.TTC-1240_R377H 186 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 159 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 405 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 258 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 368 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 422 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 101 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 382 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 474 bp overlap

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

STAT1 1 dataset

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

STAT3 2 datasets

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Motif DE_12h DE_12h-STAT3_MA0144.3 9 bp overlap

Stat4 1 dataset

Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_12h DE_12h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

TAF1 3 datasets

ChIP H1 ENCFF478SZO 383 bp overlap

ChIP H1 ENCFF478SZO 346 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 459 bp overlap

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP H1 ENCFF859IIO 362 bp overlap

ChIP H1 ENCFF859IIO 279 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 239 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 170 bp overlap

ChIP hESC GSE122298.TBP.hESC 247 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 178 bp overlap

TCF21 1 dataset

Motif DE_12h DE_12h-TCF21_MA1568.2 10 bp overlap

ChIP NPC GSE154479.TCF3.NPC 356 bp overlap

TCF7L2 1 dataset

Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 221 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 161 bp overlap

Thap11 1 dataset

Motif DE_12h DE_12h-Thap11_MA1573.2 14 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ZBTB33 1 dataset

ChIP WTC11 ENCFF048CFR 391 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 266 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 421 bp overlap

ZNF274 1 dataset

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 344 bp overlap

ZNF677 1 dataset

Motif DE_12h DE_12h-ZNF677_MA2101.1 12 bp overlap

ZSCAN21 1 dataset

Motif DE_12h DE_12h-ZSCAN21_MA2336.1 7 bp overlap