chr19:42,095,735–42,096,278

chr19 : 42,095,735 – 42,096,278

543 bp 107 TFs 16 linked genes

This 543 bp open chromatin element is linked to 16 target genes and is bound by 107 transcription factors.

Linked Genes

16 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ZNF574		19.9 kb	Distal	Multiome
GRIK5		25.8 kb	Distal	Multiome
POU2F2		36.4 kb	Distal	Multiome
ATP1A3		101.9 kb	Distal	Multiome
DEDD2		121.7 kb	Distal	Multiome
ZNF526		124.3 kb	Distal	Multiome
RABAC1		136.7 kb	Distal	Multiome
GSK3A		146.6 kb	Distal	Multiome
ERF		159.1 kb	Distal	Multiome
CIC		173.2 kb	Distal	Multiome
PAFAH1B3		206.7 kb	Distal	Multiome
ARHGEF1		212.8 kb	Distal	Multiome
TMEM145		217.4 kb	Distal	Multiome
MEGF8		229.6 kb	Distal	Multiome
RPS19		235.8 kb	Distal	Multiome
CNFN		294.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

107 transcription factors

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 106 bp overlap

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 332 bp overlap

ARNTL 1 dataset

ChIP NSC_hNP1 GSE134972.ARNTL.NSC_hNP1 307 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 252 bp overlap

Ahr::Arnt 1 dataset

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 413 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 495 bp overlap

BRD4 7 datasets

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 216 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 191 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 186 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 543 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 57 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 420 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 148 bp overlap

CBFB 2 datasets

ChIP ME-1 GSE46044.CBFB.ME-1 140 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 305 bp overlap

ChIP hESC GSE133412.CBX7.hESC 172 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 285 bp overlap

CTCF 2 datasets

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 112 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 214 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 166 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 63 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 276 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 240 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 245 bp overlap

EGR1 2 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 212 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP HEK293 ENCFF336LFH 125 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 52 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 409 bp overlap

ESR1 5 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 106 bp overlap

ChIP Ishikawa GSE99905.ESR1.Ishikawa 256 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 189 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 194 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 231 bp overlap

FLI1 2 datasets

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 202 bp overlap

ChIP UAE GSE23730.FLI1.UAE 321 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 453 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 442 bp overlap

GABPA 1 dataset

ChIP K-562 ENCSR000BLO.GABPA.K-562 174 bp overlap

GATA2 1 dataset

ChIP ME-1 GSE46044.GATA2.ME-1 238 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 264 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 150 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 284 bp overlap

HMGN3 1 dataset

ChIP K-562 ENCSR000DOB.HMGN3.K-562 230 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 192 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 254 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 209 bp overlap

KLF1 4 datasets

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

ChIP HEK293 ENCFF159QSW 455 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 543 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 322 bp overlap

KLF12 1 dataset

ChIP HEK293 GSE76494.KLF12.HEK293 183 bp overlap

KLF14 1 dataset

ChIP HEK293 ENCSR780ESQ.KLF14.HEK293 452 bp overlap

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 384 bp overlap

KLF4 2 datasets

Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap

ChIP hiPSC GSE56567.KLF4.hiPSC 147 bp overlap

KLF5 2 datasets

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

ChIP KATO-III GSE51705.KLF5.KATO-III 141 bp overlap

KLF8 2 datasets

ChIP HEK293 ENCFF929IAJ 457 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 232 bp overlap

KLF9 3 datasets

ChIP GBM1A GSE62211.KLF9.GBM1A 164 bp overlap

ChIP HEK293 ENCFF588INF 451 bp overlap

ChIP HEK293 ENCSR076EZB.KLF9.HEK293 367 bp overlap

L3MBTL2 2 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 275 bp overlap

ChIP K562 ENCFF320EQC 373 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 112 bp overlap

ChIP H1 ENCFF914VQY 231 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 131 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 157 bp overlap

ChIP WTC11 ENCFF223QFY 190 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 398 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 208 bp overlap

ChIP K562 ENCFF140CEX 374 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 228 bp overlap

MYBL2 1 dataset

ChIP WTC11 ENCFF166TKT 412 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 92 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 228 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 204 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 293 bp overlap

NCAPH2 2 datasets

ChIP HEK293 GSE97540.NCAPH2.HEK293 543 bp overlap

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 543 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 543 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 526 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 495 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 457 bp overlap

PATZ1 1 dataset

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 231 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 79 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 237 bp overlap

ChIP esophagus muscularis mucosa ENCFF791ZXN 101 bp overlap

ChIP spleen ENCFF706IUS 543 bp overlap

POU2F1 1 dataset

ChIP T-47D GSE148277.POU2F1.T-47D 264 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 425 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 147 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 363 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 366 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 272 bp overlap

RBFOX2 2 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 195 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 181 bp overlap

Motif ES_0h ES_0h-REL_MA0101.1 10 bp overlap

RELA 4 datasets

ChIP HEK293 GSE89017.RELA.HEK293 292 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 543 bp overlap

ChIP HEK293_TNF-30min GSE75562.RELA.HEK293_TNF-30min 154 bp overlap

ChIP aortic-endothelial-cell_IL1B_D33 GSE139377.RELA.aortic-endothelial-cell_IL1B_D33 218 bp overlap

ChIP PANC-1 ENCSR000BJO.REST.PANC-1 100 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 250 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 543 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 543 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 204 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 140 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 274 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 427 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 245 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 329 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 264 bp overlap

SMAD3 1 dataset

ChIP WTC11 ENCFF815YYQ 357 bp overlap

SMARCA4 1 dataset

ChIP 22Rv1 GSE115615.SMARCA4.22Rv1 85 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 277 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 251 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 147 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 378 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 543 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 543 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 543 bp overlap

ChIP H1 ENCFF478SZO 306 bp overlap

TAF15 2 datasets

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 343 bp overlap

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 227 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 325 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 357 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 352 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 543 bp overlap

TGIF2 2 datasets

ChIP WTC11 ENCFF649SHI 380 bp overlap

ChIP WTC11 ENCFF649SHI 400 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 145 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 353 bp overlap

Tfcp2l1 1 dataset

Motif DE_24h DE_24h-Tfcp2l1_MA0145.2 14 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 543 bp overlap

ChIP GM12891 ENCSR000BKJ.YY1.GM12891 113 bp overlap

ChIP K-562 ENCSR000BKU.YY1.K-562 218 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 200 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 243 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 145 bp overlap

ChIP K562 ENCFF875HLX 204 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 111 bp overlap

ZBTB7A 4 datasets

Motif ES_0h ES_0h-ZBTB7A_MA0750.3 9 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 280 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 132 bp overlap

ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 333 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 461 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 446 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF143 1 dataset

ChIP WA01 ENCSR000EBW.ZNF143.WA01 117 bp overlap

ZNF232 1 dataset

ChIP WTC11 ENCFF901BGD 398 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 69 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 218 bp overlap

ZNF343 1 dataset

Motif DE_24h DE_24h-ZNF343_MA1711.2 16 bp overlap

ZNF449 1 dataset

Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap

ZNF558 1 dataset

ChIP HEK293T GSE78099.ZNF558.HEK293T 272 bp overlap

ZNF692 1 dataset

Motif ES_0h ES_0h-ZNF692_MA1986.2 8 bp overlap

Motif ES_0h ES_0h-Zfx_MA0146.3 10 bp overlap