Enables identical protein binding activity. Located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for RABAC1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = RABAC1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of RABAC1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr19:41,706,740–41,707,217 | 252.3 kb | Distal (>10kb) Multiome | 420 | |
| chr19:41,859,455–41,860,753 | 99.4 kb | Distal (>10kb) Multiome HiCAR | 1018 | |
| chr19:41,883,883–41,884,651 | 75.0 kb | Distal (>10kb) Multiome HiCAR | 917 | |
| chr19:41,887,651–41,888,254 | 71.3 kb | Distal (>10kb) Multiome HiCAR | 553 | |
| chr19:41,927,700–41,928,620 | 31.1 kb | Distal (>10kb) Multiome | 277 | |
| chr19:41,930,462–41,931,200 | 28.3 kb | Distal (>10kb) Multiome | 147 | |
| chr19:41,951,721–41,952,145 | 7.2 kb | Proximal (<10kb) | 372 | |
| chr19:41,957,648–41,959,799 | 753 bp | At TSS Multiome | 839 | |
| chr19:41,993,779–41,994,412 | 34.9 kb | Distal (>10kb) Multiome | 360 | |
| chr19:41,998,577–41,999,349 | 39.5 kb | Distal (>10kb) Multiome | 292 | |
| chr19:42,075,557–42,076,657 | 116.7 kb | Distal (>10kb) Multiome | 846 | |
| chr19:42,095,735–42,096,278 | 136.7 kb | Distal (>10kb) Multiome | 107 | |
| chr19:42,132,949–42,133,545 | 174.0 kb | Distal (>10kb) Multiome | 447 | |
| chr19:42,176,787–42,177,398 | 217.8 kb | Distal (>10kb) Multiome | 381 | |
| chr19:42,216,521–42,218,719 | 258.4 kb | Distal (>10kb) Multiome | 841 | |
| chr19:42,219,693–42,220,678 | 260.9 kb | Distal (>10kb) Multiome | 735 | |
| chr19:42,241,985–42,243,820 | 283.6 kb | Distal (>10kb) Multiome | 891 | |
| chr19:42,244,086–42,245,258 | 285.5 kb | Distal (>10kb) Multiome | 768 | |
| chr19:42,253,030–42,256,178 | 294.6 kb | Distal (>10kb) Multiome | 900 |
Genomic view of the RABAC1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.