chr17:44,987,181–44,987,616

chr17 : 44,987,181 – 44,987,616

435 bp 93 TFs 12 linked genes

This 435 bp open chromatin element is linked to 12 target genes and is bound by 93 transcription factors.

Linked Genes

12 genes

Gene	Expression	Dist. to TSS	Distance	Link type
KIF18B		39.8 kb	Distal	Multiome
DCAKD		73.5 kb	Distal	Multiome
NMT1		73.7 kb	Distal	Multiome
EFTUD2		88.2 kb	Distal	Multiome
PLCD3		144.9 kb	Distal	Multiome
ACBD4		148.1 kb	Distal	Multiome
GJC1		156.8 kb	Distal	Multiome
HEXIM1		160.9 kb	Distal	Multiome
HEXIM2		173.5 kb	Distal	Multiome
HEXIM2-AS1		174.0 kb	Distal	Multiome
DBF4B		278.9 kb	Distal	Multiome
CCDC43		297.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

93 transcription factors

ARID1A 1 dataset

ChIP RMG-I GSE104545.ARID1A.RMG-I 187 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 210 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 287 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 262 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 256 bp overlap

BRD4 7 datasets

ChIP DND41_E GSE54379.BRD4.DND41_E 233 bp overlap

ChIP Jurkat GSE83777.BRD4.Jurkat 327 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 218 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 205 bp overlap

ChIP hESC GSE33281.BRD4.hESC 70 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 315 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 230 bp overlap

ChIP Jurkat GSE83777.CDK7.Jurkat 258 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 222 bp overlap

CTCF 2 datasets

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 219 bp overlap

ChIP gastroesophageal-sphincter ENCSR298ZPF.CTCF.gastroesophageal-sphincter 218 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 210 bp overlap

ChIP U-87MG_GBM GSE99171.E2F1.U-87MG_GBM 260 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 221 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 255 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 195 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 325 bp overlap

ETS1 2 datasets

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 147 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 331 bp overlap

EZH2 12 datasets

ChIP DND41 ENCSR000ASW.EZH2.DND41 404 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 135 bp overlap

ChIP H1 ENCFF232NZA 363 bp overlap

ChIP LNCaP GSE39459.EZH2.LNCaP 248 bp overlap

ChIP ProEs GSE59087.EZH2.ProEs 223 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 333 bp overlap

ChIP SU-DHL-6 GSE45982.EZH2.SU-DHL-6 164 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 177 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 276 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 396 bp overlap

ChIP keratinocyte ENCFF070STK 435 bp overlap

ChIP keratinocyte ENCSR000ARK.EZH2.keratinocyte 329 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 79 bp overlap

GABPA 2 datasets

ChIP H1 ENCFF739QFD 341 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 169 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 306 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 203 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 345 bp overlap

GLIS2 2 datasets

ChIP HEK293 ENCFF446EIF 405 bp overlap

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 331 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 194 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 164 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 280 bp overlap

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 298 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 190 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 279 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 271 bp overlap

KDM4A 3 datasets

ChIP H1 ENCFF078LED 402 bp overlap

ChIP H1 ENCFF078LED 201 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 256 bp overlap

KLF1 5 datasets

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

ChIP HEK293 ENCFF159QSW 342 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 353 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 275 bp overlap

KLF10 2 datasets

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

KLF12 2 datasets

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

KLF14 2 datasets

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

KLF15 2 datasets

Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap

Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap

KLF17 1 dataset

Motif DE_24h DE_24h-KLF17_MA1514.2 14 bp overlap

KLF2 2 datasets

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

KLF4 3 datasets

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 138 bp overlap

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap

KLF5 2 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

KLF7 2 datasets

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 143 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 364 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 277 bp overlap

ChIP HEK293 ENCFF994GSG 404 bp overlap

ChIP HEK293 ENCSR290SSQ.MAZ.HEK293 228 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 210 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 232 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 266 bp overlap

MYCN 2 datasets

ChIP Kelly GSE94822.MYCN.Kelly 180 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 196 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 205 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 188 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 193 bp overlap

ONECUT2 1 dataset

ChIP A-549 GSE102599.ONECUT2.A-549 293 bp overlap

PATZ1 2 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

POLR2A 1 dataset

ChIP H1 ENCFF566JSR 435 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 168 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 378 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 181 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 179 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 367 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 78 bp overlap

PRDM9 1 dataset

Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap

RAD21 1 dataset

ChIP hiPSC_IV8 GSE106870.RAD21.hiPSC_IV8 257 bp overlap

RBBP4 1 dataset

ChIP RH5 GSE155861.RBBP4.RH5 104 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 269 bp overlap

ChIP 786-O GSE86092.RELA.786-O 127 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 247 bp overlap

RUVBL2 1 dataset

ChIP Huh-7 GSE97411.RUVBL2.Huh-7 320 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 394 bp overlap

SIN3A 3 datasets

ChIP H1 ENCFF042ZSL 393 bp overlap

ChIP H1 ENCFF042ZSL 186 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 163 bp overlap

SMAD2 3 datasets

ChIP hESC GSE29422.SMAD2.hESC 193 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 369 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 264 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 376 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 415 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 405 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 435 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 396 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 395 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 435 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 377 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 199 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 383 bp overlap

SMAD3 5 datasets

ChIP BG03 GSE21614.SMAD3.BG03 142 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 207 bp overlap

ChIP H69_4TGF GSE145250.SMAD3.H69_4TGF 70 bp overlap

ChIP H69_5TGF GSE145250.SMAD3.H69_5TGF 99 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 250 bp overlap

SMAD4 1 dataset

ChIP hESC GSE29422.SMAD4.hESC 168 bp overlap

SMARCA4 7 datasets

ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 267 bp overlap

ChIP NGP GSE134626.SMARCA4.NGP 189 bp overlap

ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 75 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 156 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 267 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 291 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 196 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 258 bp overlap

SMARCC1 2 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 97 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 192 bp overlap

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

Motif DE_24h DE_24h-SP1_MA0079.5 9 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 186 bp overlap

ChIP WTC11 ENCFF688PEU 322 bp overlap

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

Motif DE_24h DE_24h-SP2_MA0516.3 9 bp overlap

ChIP HEK293 ENCFF181QXT 330 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 269 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 223 bp overlap

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 265 bp overlap

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 406 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 233 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 382 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 187 bp overlap

ChIP hESC GSE122298.TBP.hESC 142 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 159 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 227 bp overlap

TOP2A 1 dataset

ChIP KG-1_etoposide_VP16 GSE114048.TOP2A.KG-1_etoposide_VP16 114 bp overlap

ChIP WTC11 ENCFF359JCU 435 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 326 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 287 bp overlap

ZBED4 2 datasets

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

ZBTB17 2 datasets

ChIP HEK293 ENCFF865LIO 426 bp overlap

ChIP HEK293 ENCFF865LIO 435 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 223 bp overlap

ZNF148 2 datasets

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

Motif DE_24h DE_24h-ZNF148_MA1653.2 10 bp overlap

ZNF341 3 datasets

ChIP HEK293 ENCFF944VMC 327 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 378 bp overlap

ChIP HEK293 GSE76494.ZNF341.HEK293 290 bp overlap

ZNF354C 1 dataset

Motif DE_24h DE_24h-ZNF354C_MA0130.1 6 bp overlap

ZNF398 1 dataset

ChIP H9 GSE133630.ZNF398.H9 125 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 257 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 76 bp overlap

ZNF740 2 datasets

Motif DE_12h DE_12h-ZNF740_MA0753.3 10 bp overlap

Motif DE_24h DE_24h-ZNF740_MA0753.3 10 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 164 bp overlap

ZSCAN16 2 datasets

Motif DE_12h DE_12h-ZSCAN16_MA2100.1 18 bp overlap

Motif DE_24h DE_24h-ZSCAN16_MA2100.1 18 bp overlap