chr6 : 100,469,271 – 100,469,938
667 bp 114 TFs 1 linked gene
This 667 bp open chromatin element is linked to SIM1 and is bound by 114 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SIM1 4.3 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:100,464,271 – 100,474,938
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
114 transcription factors
Source
Cell type
AATF 1 dataset
ChIP NALM-6 GSE93626.AATF.NALM-6 208 bp overlap
AGO1 1 dataset
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 233 bp overlap
AR 1 dataset
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 256 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 645 bp overlap
ATF1 1 dataset
ChIP HCT-116 GSE130477.ATF1.HCT-116 400 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 102 bp overlap
BCL6 1 dataset
ChIP CD4 GSE59933.BCL6.CD4 171 bp overlap
BCOR 4 datasets
ChIP WA01 GSE104690.BCOR.WA01 517 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 332 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 490 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 667 bp overlap
BRD1 2 datasets
ChIP HUES-64 GSE104059.BRD1.HUES-64 59 bp overlap
ChIP HUES-64 GSE104059.BRD1.HUES-64 229 bp overlap
BRD4 3 datasets
ChIP COLO-741 GSE73319.BRD4.COLO-741 236 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 412 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 193 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap
CBFB 1 dataset
ChIP ME-1 GSE46044.CBFB.ME-1 219 bp overlap
CREB1 1 dataset
ChIP WA01 ENCSR000BSN.CREB1.WA01 121 bp overlap
CTBP2 3 datasets
ChIP H1 ENCFF329MAX 511 bp overlap
ChIP H1 ENCFF329MAX 547 bp overlap
ChIP WA01 ENCSR000EUO.CTBP2.WA01 436 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 428 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 212 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 419 bp overlap
ERG 1 dataset
ChIP MCF-7 GSE23730.ERG.MCF-7 266 bp overlap
ESR1 3 datasets
ChIP Ishikawa GSE99905.ESR1.Ishikawa 230 bp overlap
ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 281 bp overlap
ChIP MCF-7_estradiol-DHT_45min GSE99626.ESR1.MCF-7_estradiol-DHT_45min 243 bp overlap
ESRRA 1 dataset
Motif DE_12h DE_12h-ESRRA_MA0592.4 9 bp overlap
EZH2 30 datasets
ChIP B-cell ENCSR000AUZ.EZH2.B-cell 241 bp overlap
ChIP GM23338 ENCFF613YON 403 bp overlap
ChIP GM23338 ENCFF613YON 348 bp overlap
ChIP GM23338 ENCFF886DXX 84 bp overlap
ChIP GM23338 ENCFF886DXX 225 bp overlap
ChIP H1 ENCFF232NZA 667 bp overlap
ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 437 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 332 bp overlap
ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 344 bp overlap
ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 379 bp overlap
ChIP ProEs_SHCTR GSE59087.EZH2.ProEs_SHCTR 235 bp overlap
ChIP SK-N-SH ENCFF657FZK 284 bp overlap
ChIP astrocyte ENCFF365JTP 623 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 425 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 524 bp overlap
ChIP fibroblast of lung ENCFF479BAW 136 bp overlap
ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 174 bp overlap
ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 667 bp overlap
ChIP hESC GSE113817.EZH2.hESC 328 bp overlap
ChIP hepatocyte ENCFF118DKH 111 bp overlap
ChIP hepatocyte ENCFF118DKH 310 bp overlap
ChIP hepatocyte ENCFF552DZB 667 bp overlap
ChIP keratinocyte ENCFF070STK 244 bp overlap
ChIP keratinocyte ENCFF070STK 524 bp overlap
ChIP keratinocyte ENCFF070STK 555 bp overlap
ChIP keratinocyte ENCFF070STK 330 bp overlap
ChIP neural ENCSR511CUH.EZH2.neural 667 bp overlap
ChIP neural cell ENCFF610EPB 401 bp overlap
ChIP neural progenitor cell ENCFF018MKA 667 bp overlap
ChIP neural progenitor cell ENCFF472NFV 667 bp overlap
Esrrg 1 dataset
Motif DE_12h DE_12h-Esrrg_MA0643.2 9 bp overlap
FEZF2 1 dataset
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
FLI1 1 dataset
ChIP UAE GSE23730.FLI1.UAE 212 bp overlap
FOXP1 2 datasets
ChIP WTC11 ENCFF338WGC 472 bp overlap
ChIP WTC11 ENCFF338WGC 520 bp overlap
GATA6 3 datasets
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 288 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 56 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 298 bp overlap
GTF3C2 1 dataset
ChIP H9 GSE94418.GTF3C2.H9 204 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 354 bp overlap
HES7 1 dataset
Motif DE_12h DE_12h-HES7_MA0822.1 12 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 298 bp overlap
HNRNPLL 2 datasets
ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 194 bp overlap
ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 228 bp overlap
IRF4 1 dataset
ChIP T-cell GSE136853.IRF4.T-cell 399 bp overlap
JARID2 7 datasets
ChIP AMIPS6 GSE48516.JARID2.AMIPS6 554 bp overlap
ChIP AMIPS8 GSE48516.JARID2.AMIPS8 503 bp overlap
ChIP EDOMIPS2 GSE48516.JARID2.EDOMIPS2 667 bp overlap
ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 534 bp overlap
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 667 bp overlap
ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 595 bp overlap
ChIP UTEIPS4 GSE48516.JARID2.UTEIPS4 604 bp overlap
JUN 2 datasets
ChIP ESC S34-ESC-d0-JUN-exp2 336 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 350 bp overlap
JUND 2 datasets
Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap
ChIP H1 ENCFF468JZD 231 bp overlap
KDM4A 2 datasets
ChIP WA01 ENCSR000AVC.KDM4A.WA01 310 bp overlap
ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 247 bp overlap
KDM5B 1 dataset
ChIP Hep-G2 ENCSR227MRE.KDM5B.Hep-G2 186 bp overlap
KDM6B 1 dataset
ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 232 bp overlap
KLF10 1 dataset
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
KLF12 1 dataset
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
KLF15 1 dataset
Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap
KLF4 1 dataset
ChIP hiPSC GSE56567.KLF4.hiPSC 213 bp overlap
KLF5 1 dataset
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
MAX 1 dataset
ChIP H1 ENCFF914VQY 90 bp overlap
MEIS1 1 dataset
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MSC 1 dataset
Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap
MXI1 1 dataset
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
NANOG 2 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 606 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 296 bp overlap
NFE2L1 1 dataset
ChIP WTC11 ENCFF644BPU 377 bp overlap
NFIA 1 dataset
Motif ES_0h ES_0h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif ES_0h ES_0h-NFIX_MA0671.2 6 bp overlap
NFKB2 1 dataset
Motif DE_12h DE_12h-NFKB2_MA0778.2 11 bp overlap
NR5A1 1 dataset
Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap
NR6A1 1 dataset
Motif DE_12h DE_12h-NR6A1_MA1541.2 14 bp overlap
Nr5A2 1 dataset
Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap
OGG1 4 datasets
ChIP HEK293 GSE89017.OGG1.HEK293 470 bp overlap
ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 405 bp overlap
ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 465 bp overlap
ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 462 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH3 GSE83726.PAX3-FOXO1.RH3 208 bp overlap
PBX3 1 dataset
Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 120 bp overlap
PKNOX1 1 dataset
Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap
POU5F1 5 datasets
ChIP BG03 GSE21614.POU5F1.BG03 203 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 283 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 623 bp overlap
ChIP SKM-1 GSE93706.POU5F1.SKM-1 335 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 414 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 481 bp overlap
PRDM14 1 dataset
ChIP NCCIT GSE71675.PRDM14.NCCIT 324 bp overlap
PTBP1 2 datasets
ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 287 bp overlap
ChIP Hep-G2 GSE120104.PTBP1.Hep-G2 300 bp overlap
Pparg::Rxra 1 dataset
Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap
RARA 1 dataset
ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 240 bp overlap
RBPJ 1 dataset
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
RELA 1 dataset
ChIP HEK293_TNF-30min GSE75562.RELA.HEK293_TNF-30min 332 bp overlap
RNF2 4 datasets
ChIP H1 ENCFF239FFS 282 bp overlap
ChIP H1 ENCFF239FFS 400 bp overlap
ChIP HUES-64 GSE104059.RNF2.HUES-64 419 bp overlap
ChIP fibroblast GSE139053.RNF2.fibroblast 126 bp overlap
RORC 2 datasets
ChIP HCC70 GSE126380.RORC.HCC70 455 bp overlap
ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 316 bp overlap
RXR 1 dataset
ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 218 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 480 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 374 bp overlap
SMAD2 1 dataset
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 4 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 311 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 404 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 484 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 324 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 318 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 139 bp overlap
SMARCA4 2 datasets
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 667 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 189 bp overlap
SMARCC1 1 dataset
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 622 bp overlap
SP1 2 datasets
ChIP WA01 ENCSR000BIR.SP1.WA01 64 bp overlap
ChIP WTC11 ENCFF688PEU 500 bp overlap
SREBP2 2 datasets
ChIP HCC70 GSE126380.SREBP2.HCC70 332 bp overlap
ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 286 bp overlap
SS18 1 dataset
ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 568 bp overlap
STAT3 1 dataset
ChIP WA01 ERP004237.STAT3.WA01 182 bp overlap
SUZ12 7 datasets
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 290 bp overlap
ChIP GM12878 ENCSR091BOQ.SUZ12.GM12878 405 bp overlap
ChIP H1 ENCFF881NFR 667 bp overlap
ChIP K-562 ENCSR000AUC.SUZ12.K-562 122 bp overlap
ChIP NCCIT GSE71675.SUZ12.NCCIT 476 bp overlap
ChIP WA01 ENCSR000ATS.SUZ12.WA01 608 bp overlap
ChIP WA01 ENCSR000EUQ.SUZ12.WA01 525 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 188 bp overlap
TAF15 2 datasets
ChIP Hep-G2 GSE120104.TAF15.Hep-G2 185 bp overlap
ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 262 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 218 bp overlap
TBP 1 dataset
ChIP WA01 ENCSR000ECB.TBP.WA01 197 bp overlap
TCF12 2 datasets
ChIP WA01 ENCSR000BIT.TCF12.WA01 416 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 109 bp overlap
TCF7 1 dataset
ChIP breast-organoid_BRCA2-mut GSE113909.TCF7.breast-organoid_BRCA2-mut 411 bp overlap
TFAP2A 3 datasets
Motif DE_12h DE_12h-TFAP2A_MA0003.5 9 bp overlap
Motif DE_12h DE_12h-TFAP2A_MA0003.5 9 bp overlap
Motif ES_0h ES_0h-TFAP2A_MA0003.5 9 bp overlap
TFAP2B 5 datasets
Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap
Motif DE_12h DE_12h-TFAP2B_MA0812.2 9 bp overlap
Motif DE_12h DE_12h-TFAP2B_MA0812.2 9 bp overlap
Motif ES_0h ES_0h-TFAP2B_MA0811.2 11 bp overlap
Motif ES_0h ES_0h-TFAP2B_MA0812.2 9 bp overlap
TFAP2C 8 datasets
Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0814.3 9 bp overlap
Motif ES_0h ES_0h-TFAP2C_MA0524.3 11 bp overlap
Motif ES_0h ES_0h-TFAP2C_MA0814.3 9 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 660 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 359 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 249 bp overlap
TFAP2E 3 datasets
Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap
Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap
Motif ES_0h ES_0h-TFAP2E_MA1569.2 9 bp overlap
TFAP4::FLI1 1 dataset
Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap
TGIF2 1 dataset
ChIP WTC11 ENCFF649SHI 441 bp overlap
THRB 1 dataset
Motif DE_12h DE_12h-THRB_MA1575.2 17 bp overlap
TP63 1 dataset
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 235 bp overlap
TRIM25 1 dataset
ChIP BT-549 GSE79588.TRIM25.BT-549 175 bp overlap
ZBED4 1 dataset
Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap
ZBTB24 1 dataset
Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 480 bp overlap
ZBTB7C 1 dataset
Motif DE_12h DE_12h-ZBTB7C_MA0695.2 8 bp overlap
ZIC1 1 dataset
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
ZIC5 1 dataset
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
ZNF16 1 dataset
Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap
ZNF343 2 datasets
Motif DE_12h DE_12h-ZNF343_MA1711.2 16 bp overlap
Motif ES_0h ES_0h-ZNF343_MA1711.2 16 bp overlap
ZNF417 1 dataset
Motif DE_12h DE_12h-ZNF417_MA1727.2 7 bp overlap
ZNF423 1 dataset
ChIP WTC11 ENCFF574PBR 162 bp overlap
ZNF460 1 dataset
Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap
ZNF610 2 datasets
Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap
Motif ES_0h ES_0h-ZNF610_MA1713.2 10 bp overlap
ZNF692 1 dataset
Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap
ZNF701 1 dataset
Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap
ZNF816 1 dataset
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
Znf423 1 dataset
Motif DE_12h DE_12h-Znf423_MA0116.1 15 bp overlap
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