chr6:44,185,920–44,186,571

chr6 : 44,185,920 – 44,186,571

651 bp 95 TFs 8 linked genes

This 651 bp open chromatin element is linked to 8 target genes and is bound by 95 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC29A1		37.3 kb	Distal	Multiome
TMEM63B		58.6 kb	Distal	Multiome
MRPL14		58.8 kb	Distal	Multiome
HSP90AB1		60.9 kb	Distal	Multiome
SLC35B2		71.3 kb	Distal	Multiome
SCIRT		111.6 kb	Distal	Multiome
AARS2		127.1 kb	Distal	Multiome
CDC5L		201.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

95 transcription factors

ChIP MCF-7 GSE48930.AR.MCF-7 232 bp overlap

ARID2 1 dataset

ChIP K-562 ENCSR491EBY.ARID2.K-562 224 bp overlap

BHLHE40 1 dataset

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 136 bp overlap

BRD2 2 datasets

ChIP K-562 GSE140325.BRD2.K-562 143 bp overlap

ChIP K-562 GSE140325.BRD2.K-562 340 bp overlap

BRD3 2 datasets

ChIP K-562_DMSO GSE120715.BRD3.K-562_DMSO 232 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 201 bp overlap

BRD4 6 datasets

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 96 bp overlap

ChIP HUVEC-C GSE53998.BRD4.HUVEC-C 290 bp overlap

ChIP K-562_JQ1_2h GSE99178.BRD4.K-562_JQ1_2h 131 bp overlap

ChIP K-562_iBET GSE138084.BRD4.K-562_iBET 64 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 244 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 651 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 239 bp overlap

CREBBP 1 dataset

ChIP tonsil_GCBc_p4 GSE89688.CREBBP.tonsil_GCBc_p4 294 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 400 bp overlap

CTCF 3 datasets

ChIP Hep-G2 ENCSR000DUG.CTCF.Hep-G2 100 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 295 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DVP.CTCF.endothelial_umbilical-vein 141 bp overlap

ChIP K-562 ENCSR000EWL.E2F4.K-562 105 bp overlap

E2F6 5 datasets

ChIP K-562 ENCSR000BLI.E2F6.K-562 137 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 196 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 129 bp overlap

ChIP K562 ENCFF136LTS 325 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 311 bp overlap

ChIP ProEs GSE59087.EED.ProEs 132 bp overlap

ChIP HEK293 ENCFF336LFH 220 bp overlap

ELF1 2 datasets

ChIP K-562 ENCSR000BMD.ELF1.K-562 128 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 139 bp overlap

EP400 1 dataset

ChIP K562 ENCFF850OZQ 651 bp overlap

ERG 21 datasets

ChIP HAEC GSE89970.ERG.HAEC 185 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 247 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 360 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 410 bp overlap

ChIP aortic-endothelial-cell_D13 GSE139377.ERG.aortic-endothelial-cell_D13 172 bp overlap

ChIP aortic-endothelial-cell_D14 GSE139377.ERG.aortic-endothelial-cell_D14 250 bp overlap

ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 322 bp overlap

ChIP aortic-endothelial-cell_D17 GSE139377.ERG.aortic-endothelial-cell_D17 178 bp overlap

ChIP aortic-endothelial-cell_D19 GSE139377.ERG.aortic-endothelial-cell_D19 162 bp overlap

ChIP aortic-endothelial-cell_D21 GSE139377.ERG.aortic-endothelial-cell_D21 166 bp overlap

ChIP aortic-endothelial-cell_D24 GSE139377.ERG.aortic-endothelial-cell_D24 223 bp overlap

ChIP aortic-endothelial-cell_D28 GSE139377.ERG.aortic-endothelial-cell_D28 331 bp overlap

ChIP aortic-endothelial-cell_D33 GSE139377.ERG.aortic-endothelial-cell_D33 222 bp overlap

ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 235 bp overlap

ChIP aortic-endothelial-cell_D40 GSE139377.ERG.aortic-endothelial-cell_D40 245 bp overlap

ChIP aortic-endothelial-cell_D46 GSE139377.ERG.aortic-endothelial-cell_D46 205 bp overlap

ChIP aortic-endothelial-cell_D47 GSE139377.ERG.aortic-endothelial-cell_D47 320 bp overlap

ChIP aortic-endothelial-cell_D49 GSE139377.ERG.aortic-endothelial-cell_D49 331 bp overlap

ChIP aortic-endothelial-cell_D5 GSE139377.ERG.aortic-endothelial-cell_D5 213 bp overlap

ChIP aortic-endothelial-cell_D51 GSE139377.ERG.aortic-endothelial-cell_D51 387 bp overlap

ChIP aortic-endothelial-cell_D53 GSE139377.ERG.aortic-endothelial-cell_D53 163 bp overlap

ESR1 2 datasets

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 300 bp overlap

ChIP breast_mrnahist ERP002305.ESR1.breast_mrnahist 123 bp overlap

ETS1 7 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 254 bp overlap

ChIP HUVEC-C_12h GSE93030.ETS1.HUVEC-C_12h 588 bp overlap

ChIP HUVEC-C_4h GSE93030.ETS1.HUVEC-C_4h 244 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 301 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.ETS1.HUVEC-C_VEGF_12h 590 bp overlap

ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 247 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.ETS1.HUVEC-C_VEGF_4h 244 bp overlap

ChIP GIST-T1 GSE106624.ETV1.GIST-T1 117 bp overlap

EZH2 2 datasets

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 245 bp overlap

ChIP WSU-DLCL2 GSE45982.EZH2.WSU-DLCL2 228 bp overlap

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 323 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 472 bp overlap

ChIP DE DE-FOXA2-2 391 bp overlap

GABPB1 2 datasets

ChIP K-562 ENCSR138YYY.GABPB1.K-562 438 bp overlap

ChIP K562 ENCFF015GDS 465 bp overlap

GATA2 2 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 278 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 199 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 310 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-2 445 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 398 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 410 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 309 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 389 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 502 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 500 bp overlap

ChIP foregut GSE117136.GATA6.foregut 386 bp overlap

GRHL2 1 dataset

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 87 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR387UWP.HDAC1.K-562 195 bp overlap

HDAC8 2 datasets

ChIP K-562 ENCSR835TCD.HDAC8.K-562 317 bp overlap

ChIP K562 ENCFF784HCJ 310 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 252 bp overlap

HMGB2 1 dataset

ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 263 bp overlap

HNF1B 2 datasets

ChIP Hep-G2 ENCSR127XTZ.HNF1B.Hep-G2 158 bp overlap

ChIP HepG2 ENCFF928THX 313 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 56 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 503 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 330 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 339 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 328 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 293 bp overlap

ChIP HepG2 ENCFF890JFC 286 bp overlap

KMT2B-D 1 dataset

ChIP SW480 GSE115985.KMT2B-D.SW480 391 bp overlap

L3MBTL2 3 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 523 bp overlap

ChIP K562 ENCFF320EQC 523 bp overlap

ChIP K562 ENCFF320EQC 319 bp overlap

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 328 bp overlap

ChIP HepG2 ENCFF507HCX 592 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 420 bp overlap

ChIP K562 ENCFF398VJM 404 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 151 bp overlap

MED1 6 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 275 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 428 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 299 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 512 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 604 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 259 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 54 bp overlap

ChIP K-562 ENCSR710WLO.MGA.K-562 317 bp overlap

ChIP K562 ENCFF140CEX 527 bp overlap

ChIP RH4 GSE155861.MTA2.RH4 109 bp overlap

ChIP K-562 ENCSR914NEI.MTA3.K-562 433 bp overlap

MTERF4 1 dataset

ChIP HepG2 ENCFF831NAM 519 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 289 bp overlap

ChIP Hep-G2 ENCSR441KFW.MXD4.Hep-G2 167 bp overlap

ChIP K-562 ENCSR000EGJ.MYC.K-562 269 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DLU.MYC.endothelial_umbilical-vein 100 bp overlap

ChIP Hep-G2 ENCSR398TMP.MYNN.Hep-G2 153 bp overlap

MYOD1 2 datasets

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 161 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 135 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 263 bp overlap

NEUROD1 1 dataset

ChIP K-562 ENCSR986CDX.NEUROD1.K-562 207 bp overlap

NFATC1 1 dataset

ChIP HUVEC-C_VEGF GSE49428.NFATC1.HUVEC-C_VEGF 229 bp overlap

NFRKB 1 dataset

ChIP K-562 ENCSR657EOF.NFRKB.K-562 278 bp overlap

NR2C1 1 dataset

ChIP K562 ENCFF568JLK 364 bp overlap

NRF1 7 datasets

ChIP Hep-G2 ENCSR853ADA.NRF1.Hep-G2 160 bp overlap

ChIP HepG2 ENCFF694NVY 413 bp overlap

ChIP K-562 ENCSR837EYC.NRF1.K-562 157 bp overlap

ChIP K-562_Ab_R157-1-3D4 GSE97661.NRF1.K-562_Ab_R157-1-3D4 104 bp overlap

ChIP K-562_Ab_R157-1-3H3 GSE97661.NRF1.K-562_Ab_R157-1-3H3 135 bp overlap

ChIP K562 ENCFF130SGK 327 bp overlap

ChIP K562 ENCFF689EWI 531 bp overlap

PDX1 2 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 356 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 150 bp overlap

POU2F1 1 dataset

ChIP HepG2 ENCFF422JZU 238 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 448 bp overlap

PPARG 2 datasets

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 197 bp overlap

ChIP HUVEC-C_PPARG_HYPO GSE50144.PPARG.HUVEC-C_PPARG_HYPO 132 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

PRPF4 2 datasets

ChIP Hep-G2 GSE120104.PRPF4.Hep-G2 169 bp overlap

ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 184 bp overlap

RAD21 2 datasets

ChIP HCT-116 GSE131606.RAD21.HCT-116 194 bp overlap

ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 155 bp overlap

RELA 14 datasets

ChIP 786-O GSE86092.RELA.786-O 181 bp overlap

ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 215 bp overlap

ChIP aortic-endothelial-cell_IL1B_D2 GSE139377.RELA.aortic-endothelial-cell_IL1B_D2 165 bp overlap

ChIP aortic-endothelial-cell_IL1B_D27 GSE139377.RELA.aortic-endothelial-cell_IL1B_D27 238 bp overlap

ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 152 bp overlap

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 219 bp overlap

ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 165 bp overlap

ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 221 bp overlap

ChIP aortic-endothelial-cell_IL1B_D47 GSE139377.RELA.aortic-endothelial-cell_IL1B_D47 274 bp overlap

ChIP aortic-endothelial-cell_IL1B_D49 GSE139377.RELA.aortic-endothelial-cell_IL1B_D49 245 bp overlap

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 155 bp overlap

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 135 bp overlap

ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 298 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 365 bp overlap

RYBP 2 datasets

ChIP WA01 GSE104690.RYBP.WA01 395 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 68 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 275 bp overlap

SHOX2 1 dataset

ChIP K-562 ENCSR184IQF.SHOX2.K-562 247 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 525 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 321 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 554 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 346 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 360 bp overlap

ChIP HCAEC GSE101921.SMC1.HCAEC 590 bp overlap

SNAI2 2 datasets

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 126 bp overlap

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 225 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 447 bp overlap

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 108 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 182 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 263 bp overlap

ChIP hESC GSE122298.TBP.hESC 132 bp overlap

TFDP1 2 datasets

ChIP K562 ENCFF794ZXJ 651 bp overlap

ChIP K562 ENCFF794ZXJ 631 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 193 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 253 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 440 bp overlap

ZBTB7A 2 datasets

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 353 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 330 bp overlap

ZBTB7B 1 dataset

ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 296 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 423 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 263 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 110 bp overlap

ZNF263 1 dataset

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 88 bp overlap

ZNF276 1 dataset

ChIP Hep-G2 ENCSR076KLJ.ZNF276.Hep-G2 207 bp overlap

ZNF292 1 dataset

ChIP HepG2 ENCFF975MAJ 410 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 134 bp overlap

ZNF501 1 dataset

ChIP Hep-G2 ENCSR227PHM.ZNF501.Hep-G2 405 bp overlap

ZNF790 1 dataset

ChIP HepG2 ENCFF743NFR 533 bp overlap