chr18:79,960,055–79,960,750

chr18 : 79,960,055 – 79,960,750

695 bp 94 TFs 9 linked genes

This 695 bp open chromatin element is linked to 9 target genes and is bound by 94 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
HSBP1L1		3.8 kb	Proximal	Proximity
SLC66A2		8.4 kb	Proximal	Proximity
TXNL4A		73.5 kb	Distal	Multiome
RBFA		74.0 kb	Distal	Multiome
RBFADN		86.4 kb	Distal	Multiome
ADNP2		148.8 kb	Distal	Multiome
PARD6G-AS1		187.4 kb	Distal	Multiome
CTDP1		280.6 kb	Distal	Multiome
PARD6G		287.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

94 transcription factors

ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 145 bp overlap

ChIP breast-cancer_ENOB-2854 GSE128018.AR.breast-cancer_ENOB-2854 202 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 106 bp overlap

BHLHE40 6 datasets

ChIP GM12878 ENCFF521IZR 281 bp overlap

ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 190 bp overlap

ChIP IMR-90 ENCFF312JYK 147 bp overlap

ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 207 bp overlap

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 148 bp overlap

ChIP K562 ENCFF923NJI 311 bp overlap

ChIP HEK293T GSE39579.BRD3.HEK293T 76 bp overlap

BRD4 5 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 231 bp overlap

ChIP Jurkat GSE83777.BRD4.Jurkat 200 bp overlap

ChIP MDA-MB-231_MGSK2801 GSE116879.BRD4.MDA-MB-231_MGSK2801 193 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 258 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 108 bp overlap

CBFA2T2 1 dataset

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 371 bp overlap

ChIP K562 ENCFF673OEZ 273 bp overlap

CREBBP 1 dataset

ChIP keratinocyte GSE140991.CREBBP.keratinocyte 232 bp overlap

CTCF 44 datasets

ChIP 22Rv1 ENCFF466OXN 681 bp overlap

ChIP 22Rv1 ENCFF466OXN 474 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP H9 ENCFF152GTF 461 bp overlap

ChIP HeLa-S3 ENCFF255ASZ 425 bp overlap

ChIP IMR-90 ENCFF887MRH 245 bp overlap

ChIP K562 ENCFF400DFR 241 bp overlap

ChIP MCF-7 ENCFF494VXA 231 bp overlap

ChIP PC-3 ENCFF487TUI 485 bp overlap

ChIP Peyer's patch ENCFF701KWW 351 bp overlap

ChIP Peyer's patch ENCFF746TCR 152 bp overlap

ChIP Peyer's patch ENCFF828IDE 341 bp overlap

ChIP RWPE-2 ENCSR856JJB.CTCF.RWPE-2 331 bp overlap

ChIP RWPE2 ENCFF911IEE 593 bp overlap

ChIP RWPE2 ENCFF911IEE 593 bp overlap

ChIP astrocyte of the cerebellum ENCFF511OCS 345 bp overlap

ChIP bronchial epithelial cell ENCFF500SEA 271 bp overlap

ChIP choroid plexus epithelial cell ENCFF407YNR 277 bp overlap

ChIP endodermal cell ENCFF471YCZ 461 bp overlap

ChIP epithelial cell of esophagus ENCFF946GGT 305 bp overlap

ChIP epithelial cell of esophagus ENCFF946GGT 289 bp overlap

ChIP epithelial cell of prostate ENCFF086GTI 433 bp overlap

ChIP esophagus squamous epithelium ENCFF037IYT 100 bp overlap

ChIP esophagus squamous epithelium ENCFF571ODZ 365 bp overlap

ChIP esophagus squamous epithelium ENCFF683HYK 351 bp overlap

ChIP fibroblast of dermis ENCFF986DNJ 297 bp overlap

ChIP foreskin keratinocyte ENCFF980OWR 381 bp overlap

ChIP hepatocyte ENCFF263BLJ 345 bp overlap

ChIP keratinocyte ENCFF046PBT 185 bp overlap

ChIP keratinocyte ENCFF805QIE 361 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 181 bp overlap

ChIP keratinocyte ENCSR000ALJ.CTCF.keratinocyte 178 bp overlap

ChIP lower lobe of right lung ENCFF092XHT 457 bp overlap

ChIP mammary epithelial cell ENCFF164SPU 265 bp overlap

ChIP mammary epithelial cell ENCFF873ERE 271 bp overlap

ChIP retinal pigment epithelial cell ENCFF810AAG 257 bp overlap

ChIP thyroid gland ENCFF163TUI 477 bp overlap

ChIP thyroid gland ENCFF204HWS 218 bp overlap

ChIP thyroid gland ENCFF300RYK 445 bp overlap

ChIP thyroid gland ENCFF631QRY 457 bp overlap

ChIP thyroid gland ENCFF748ICQ 311 bp overlap

ChIP transverse colon ENCFF471AZS 417 bp overlap

ChIP upper lobe of left lung ENCFF277NLT 431 bp overlap

ChIP upper lobe of left lung ENCFF962AIJ 425 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 251 bp overlap

ChIP K-562 ENCSR219BXP.DPF2.K-562 145 bp overlap

ChIP K562 ENCFF136LTS 325 bp overlap

ChIP K562 ENCFF622HMZ 599 bp overlap

EP300 1 dataset

ChIP upper lobe of left lung ENCFF024QBJ 261 bp overlap

ChIP K562 ENCFF389WTI 361 bp overlap

FOSL1 1 dataset

ChIP K562 ENCFF455MKD 695 bp overlap

FOXA1 8 datasets

ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 279 bp overlap

ChIP PDAC GSE64557.FOXA1.PDAC 226 bp overlap

ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 213 bp overlap

ChIP breast-cancer_ENOB-2852 GSE128018.FOXA1.breast-cancer_ENOB-2852 111 bp overlap

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 265 bp overlap

ChIP breast-cancer_Veh-2858 GSE128018.FOXA1.breast-cancer_Veh-2858 210 bp overlap

ChIP breast-cancer_Veh-2860 GSE128018.FOXA1.breast-cancer_Veh-2860 185 bp overlap

ChIP prostate-cancer_PDX_189-3 GSE130408.FOXA1.prostate-cancer_PDX_189-3 80 bp overlap

FOXA2 4 datasets

ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 315 bp overlap

ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 236 bp overlap

ChIP DE DE-FOXA2-1 596 bp overlap

ChIP DE DE-FOXA2-2 559 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

GATA1 1 dataset

ChIP erythroblast ENCFF867JAR 463 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 551 bp overlap

ChIP DE DE-GATA4-2 613 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 234 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 577 bp overlap

ChIP DE DE-GATA6-2 611 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 664 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 667 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 616 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 618 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 315 bp overlap

HDAC1 2 datasets

ChIP K562 ENCFF928TKZ 457 bp overlap

ChIP K562 ENCFF968WBH 455 bp overlap

HDAC2 3 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 269 bp overlap

ChIP K562 ENCFF744ALD 175 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 204 bp overlap

HES1 2 datasets

ChIP K-562 ENCSR091JXL.HES1.K-562 344 bp overlap

ChIP K562 ENCFF919JVU 136 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 346 bp overlap

ChIP K562 ENCFF055GAZ 384 bp overlap

ChIP K562 ENCFF317JJX 521 bp overlap

HOXB13 1 dataset

ChIP prostate_P7_T GSE130408.HOXB13.prostate_P7_T 96 bp overlap

IKZF1 1 dataset

ChIP K562 ENCFF771OHZ 497 bp overlap

JMJD1C 1 dataset

ChIP HL-60 GSE63484.JMJD1C.HL-60 230 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 380 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 280 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 274 bp overlap

ChIP Karpas-299 GSE151413.JUN.Karpas-299 110 bp overlap

ChIP K562 ENCFF830LVJ 281 bp overlap

KDM1A 3 datasets

ChIP K562 ENCFF128TYE 206 bp overlap

ChIP K562 ENCFF133OLU 116 bp overlap

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 248 bp overlap

KLF1 2 datasets

ChIP HEK293 ENCFF159QSW 419 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 391 bp overlap

KLF17 2 datasets

ChIP HEK293 ENCFF658MHR 387 bp overlap

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 229 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 159 bp overlap

ChIP PDAC GSE64557.KLF4.PDAC 337 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 240 bp overlap

ChIP PDAC GSE64557.KLF6.PDAC 269 bp overlap

ChIP HEK293 ENCFF599UKL 359 bp overlap

L3MBTL2 2 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 297 bp overlap

ChIP K562 ENCFF320EQC 196 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 169 bp overlap

ChIP K562 ENCFF198WCP 457 bp overlap

ChIP islet ERP004003.MAFB.islet 59 bp overlap

MAML1 1 dataset

ChIP SCC_4h GSE156486.MAML1.SCC_4h 198 bp overlap

MAX 11 datasets

ChIP H1 ENCFF601FOM 325 bp overlap

ChIP H1 ENCFF914VQY 142 bp overlap

ChIP HepG2 ENCFF507HCX 505 bp overlap

ChIP HepG2 ENCFF507HCX 605 bp overlap

ChIP K562 ENCFF110LJS 351 bp overlap

ChIP K562 ENCFF398VJM 537 bp overlap

ChIP K562 ENCFF524IJO 168 bp overlap

ChIP MCF-7 ENCFF169IXS 437 bp overlap

ChIP MDA-MB-231 GSE127192.MAX.MDA-MB-231 337 bp overlap

ChIP NB4 ENCFF966MWB 277 bp overlap

ChIP WTC11 ENCFF223QFY 541 bp overlap

ChIP HepG2 ENCFF057YJE 591 bp overlap

ChIP K562 ENCFF140CEX 447 bp overlap

ChIP K-562 ENCSR512NLO.MNT.K-562 262 bp overlap

ChIP K-562 ENCSR390VGH.MNT.K-562 305 bp overlap

ChIP K562 ENCFF342DNS 519 bp overlap

ChIP K562 ENCFF450LDL 154 bp overlap

ChIP K562 ENCFF820IGH 399 bp overlap

ChIP RH4 GSE155861.MTA2.RH4 188 bp overlap

ChIP H1 ENCFF963FZS 337 bp overlap

ChIP GP5D GSE51234.MYC.GP5D 289 bp overlap

ChIP H1 ENCFF794ZJT 265 bp overlap

ChIP Jurkat GSE83777.MYC.Jurkat 187 bp overlap

ChIP K-562 ENCSR000FAG.MYC.K-562 109 bp overlap

ChIP K562 ENCFF988ZRU 400 bp overlap

NANOG 5 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 301 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 117 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 339 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 210 bp overlap

NCOA2 1 dataset

ChIP K562 ENCFF365JLH 405 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF788MPU 421 bp overlap

NR2C2 1 dataset

ChIP K562 ENCFF750AXF 695 bp overlap

NR2F1 1 dataset

ChIP K562 ENCFF221HJH 363 bp overlap

NR2F6 1 dataset

ChIP K562 ENCFF674RQA 457 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 222 bp overlap

OTX2 2 datasets

ChIP WTC11 ENCFF634NAO 72 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 225 bp overlap

ChIP H9_DOX GSE98976.PAX7.H9_DOX 192 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 119 bp overlap

POLR2A 9 datasets

ChIP Peyer's patch ENCFF767HVN 417 bp overlap

ChIP erythroblast ENCFF498VMR 695 bp overlap

ChIP esophagus squamous epithelium ENCFF708IOX 461 bp overlap

ChIP thyroid gland ENCFF979LRR 491 bp overlap

ChIP transverse colon ENCFF193UMS 571 bp overlap

ChIP transverse colon ENCFF607LKE 371 bp overlap

ChIP transverse colon ENCFF610RWV 178 bp overlap

ChIP transverse colon ENCFF840PXT 321 bp overlap

ChIP vagina ENCFF305NWS 477 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 453 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 260 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 228 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 387 bp overlap

RAD21 6 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP H1 ENCFF967OJF 245 bp overlap

ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 312 bp overlap

ChIP HeLa-S3 ENCFF775CHI 231 bp overlap

ChIP K562 ENCFF169SQI 171 bp overlap

ChIP K562 ENCFF634XYR 365 bp overlap

RAD51 2 datasets

ChIP K562 ENCFF133ELP 302 bp overlap

ChIP K562 ENCFF133ELP 405 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 123 bp overlap

ChIP SCC_4h GSE156486.RBPJ.SCC_4h 210 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP GM12878 ENCFF217ADF 552 bp overlap

RNF2 3 datasets

ChIP K562 ENCFF061ATI 445 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 209 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 194 bp overlap

SIN3A 1 dataset

ChIP H1 ENCFF896IJG 301 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 192 bp overlap

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 63 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 463 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 592 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 307 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 260 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 123 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 107 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 244 bp overlap

ChIP K562 ENCFF059YCJ 428 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP HEK293 ENCFF733RBE 537 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCFF827PZY 337 bp overlap

ChIP HL-60 ENCFF645GBT 264 bp overlap

TCF3 3 datasets

ChIP K562 ENCFF319QZT 381 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 234 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 155 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 405 bp overlap

USF1 4 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 121 bp overlap

ChIP WTC11 ENCFF699QGS 411 bp overlap

ChIP WTC11 ENCFF699QGS 425 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP HEK293 ENCFF906HIR 431 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 457 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 117 bp overlap

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 125 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 139 bp overlap

ZBTB48 2 datasets

ChIP HEK293 ENCFF809BPK 465 bp overlap

ChIP HEK293 ENCFF809BPK 457 bp overlap

ZNF263 2 datasets

ChIP HEK293 ENCFF336CWQ 483 bp overlap

ChIP HEK293 ENCFF336CWQ 591 bp overlap

ZNF281 2 datasets

ChIP K562 ENCFF594VNM 194 bp overlap

ChIP WTC11 ENCFF551GAV 377 bp overlap

ZNF501 1 dataset

ChIP HEK293 ENCSR461ZJT.ZNF501.HEK293 83 bp overlap

ZNF652 2 datasets

ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 95 bp overlap

ChIP HepG2 ENCFF331VPZ 368 bp overlap

ZSCAN4 1 dataset

ChIP HEK293 ENCFF381BKT 409 bp overlap

ZXDB 2 datasets

ChIP HEK293 ENCFF835SGA 456 bp overlap

ChIP HEK293 ENCFF835SGA 525 bp overlap