chr16:29,708,839–29,709,431

chr16 : 29,708,839 – 29,709,431

592 bp 96 TFs 16 linked genes

This 592 bp open chromatin element is linked to 16 target genes and is bound by 96 transcription factors.

Linked Genes

16 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000289181		at TSS	At TSS	Proximity
ENSG00000260719		36.2 kb	Distal	Multiome
QPRT		45.8 kb	Distal	Multiome
KIF22		81.7 kb	Distal	Multiome
MAZ		97.0 kb	Distal	Multiome
MVP-DT		102.9 kb	Distal	Multiome
PRRT2		103.1 kb	Distal	Multiome
PAGR1		107.1 kb	Distal	Multiome
CDIPT		154.1 kb	Distal	Multiome
SEZ6L2		190.5 kb	Distal	Multiome
ASPHD1		191.3 kb	Distal	Multiome
KCTD13		217.1 kb	Distal	Multiome
TMEM219		253.0 kb	Distal	Multiome
TAOK2		264.8 kb	Distal	Multiome
INO80E		286.6 kb	Distal	Multiome
HIRIP3		287.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

96 transcription factors

ARID4B 2 datasets

ChIP WTC11 ENCFF441HDK 276 bp overlap

ChIP WTC11 ENCFF441HDK 54 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 438 bp overlap

ChIP H1 ENCFF399KAM 592 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 82 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 173 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 183 bp overlap

BACH1 1 dataset

ChIP H1 ENCFF282VDB 251 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 102 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 264 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 96 bp overlap

Bcl11B 2 datasets

Motif DE_24h DE_24h-Bcl11B_MA1989.2 9 bp overlap

Motif ES_0h ES_0h-Bcl11B_MA1989.2 9 bp overlap

CHD1 3 datasets

ChIP H1 ENCFF998XEK 241 bp overlap

ChIP H1 ENCFF998XEK 241 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 238 bp overlap

ChIP H1 ENCFF991MKH 320 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 245 bp overlap

CREM 2 datasets

ChIP WTC11 ENCFF209ZUE 314 bp overlap

ChIP WTC11 ENCFF209ZUE 462 bp overlap

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 170 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 164 bp overlap

ChIP H1 ENCFF785DWK 360 bp overlap

ESRRA 1 dataset

ChIP WTC11 ENCFF591YCA 362 bp overlap

ChIP WTC11 ENCFF812SCD 388 bp overlap

FEZF2 2 datasets

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

FIGLA 2 datasets

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 345 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 248 bp overlap

GTF2F1 2 datasets

ChIP H1 ENCFF399TGL 345 bp overlap

ChIP WA01 ENCSR000EBP.GTF2F1.WA01 115 bp overlap

Gli1 2 datasets

Motif DE_24h DE_24h-Gli1_MA1990.2 10 bp overlap

Motif ES_0h ES_0h-Gli1_MA1990.2 10 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 97 bp overlap

HIC2 2 datasets

Motif DE_24h DE_24h-HIC2_MA0738.2 6 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 348 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 338 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 107 bp overlap

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

ChIP H1 ENCFF914VQY 218 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 165 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 285 bp overlap

ChIP WTC11 ENCFF223QFY 467 bp overlap

Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap

MEIS1 2 datasets

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MXI1 2 datasets

Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap

ChIP WA01 ENCSR000EBR.MXI1.WA01 169 bp overlap

ChIP H1 ENCFF794ZJT 265 bp overlap

ChIP WA01 ENCSR000EBY.MYC.WA01 118 bp overlap

MYOD1 2 datasets

Motif DE_24h DE_24h-MYOD1_MA0499.3 9 bp overlap

Motif ES_0h ES_0h-MYOD1_MA0499.3 9 bp overlap

MZF1 2 datasets

Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap

Motif ES_0h ES_0h-MZF1_MA0056.3 8 bp overlap

Msgn1 1 dataset

Motif DE_24h DE_24h-Msgn1_MA1524.3 10 bp overlap

NANOG 3 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 380 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 204 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 132 bp overlap

PATZ1 3 datasets

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

PAX4 2 datasets

Motif DE_24h DE_24h-PAX4_MA0068.2 8 bp overlap

Motif ES_0h ES_0h-PAX4_MA0068.2 8 bp overlap

PBX3 3 datasets

Motif DE_24h DE_24h-PBX3_MA1114.2 11 bp overlap

Motif ES_0h ES_0h-PBX3_MA1114.2 11 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 92 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 241 bp overlap

PHF8 3 datasets

ChIP H1 ENCFF427UFV 194 bp overlap

ChIP H1 ENCFF427UFV 92 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 200 bp overlap

PKNOX1 7 datasets

Motif DE_24h DE_24h-PKNOX1_MA0782.3 10 bp overlap

Motif ES_0h ES_0h-PKNOX1_MA0782.3 10 bp overlap

ChIP GM12878 ENCFF589FCY 223 bp overlap

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 267 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 291 bp overlap

ChIP K562 ENCFF236IUS 420 bp overlap

ChIP MCF-7 ENCFF116OCS 411 bp overlap

POLR2A 7 datasets

ChIP GM23338 ENCFF450WCS 374 bp overlap

ChIP H1 ENCFF566JSR 426 bp overlap

ChIP H1 ENCFF770YBQ 441 bp overlap

ChIP H1 ENCFF833NJP 264 bp overlap

ChIP H1 ENCFF833NJP 149 bp overlap

ChIP Raji ENCFF613VGX 185 bp overlap

ChIP Raji ENCFF613VGX 288 bp overlap

POU1F1 3 datasets

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1 3 datasets

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 4 datasets

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

ChIP GM12891 ENCFF166YPP 298 bp overlap

POU2F3 4 datasets

Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap

Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap

Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 592 bp overlap

POU3F1 3 datasets

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 3 datasets

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 3 datasets

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 3 datasets

Motif DE_24h DE_24h-POU3F4_MA0789.1 9 bp overlap

Motif DE_24h DE_24h-POU3F4_MA0789.1 9 bp overlap

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU5F1 9 datasets

Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap

Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 376 bp overlap

Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 390 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 200 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 232 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 560 bp overlap

POU5F1B 3 datasets

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 350 bp overlap

PRDM10 2 datasets

ChIP K-562 ENCSR120MPG.PRDM10.K-562 329 bp overlap

ChIP K562 ENCFF740YLK 417 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ptf1A 2 datasets

Motif DE_24h DE_24h-Ptf1A_MA1620.2 8 bp overlap

Motif ES_0h ES_0h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_24h DE_24h-RARA_MA0729.1 18 bp overlap

ChIP H1 ENCFF429RUE 245 bp overlap

RUNX2 2 datasets

Motif DE_24h DE_24h-RUNX2_MA0511.2 9 bp overlap

Motif ES_0h ES_0h-RUNX2_MA0511.2 9 bp overlap

Runx1 2 datasets

Motif DE_24h DE_24h-Runx1_MA0002.3 9 bp overlap

Motif ES_0h ES_0h-Runx1_MA0002.3 9 bp overlap

SAP30 3 datasets

ChIP H1 ENCFF149IOE 390 bp overlap

ChIP H1 ENCFF149IOE 136 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 321 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000EBO.SIN3A.WA01 264 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 171 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 229 bp overlap

SNAI2 3 datasets

Motif DE_24h DE_24h-SNAI2_MA0745.3 8 bp overlap

Motif ES_0h ES_0h-SNAI2_MA0745.3 8 bp overlap

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 74 bp overlap

SNAI3 2 datasets

Motif DE_24h DE_24h-SNAI3_MA1559.2 9 bp overlap

Motif ES_0h ES_0h-SNAI3_MA1559.2 9 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 401 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

TAF1 3 datasets

ChIP H1 ENCFF478SZO 317 bp overlap

ChIP H1 ENCFF478SZO 113 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 186 bp overlap

TAF7 2 datasets

ChIP H1 ENCFF061XZZ 193 bp overlap

ChIP WA01 ENCSR000BLU.TAF7.WA01 251 bp overlap

TBP 11 datasets

ChIP H1 ENCFF859IIO 256 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 416 bp overlap

ChIP hESC GSE122298.TBP.hESC 372 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 318 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 331 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 69 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 318 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 371 bp overlap

ChIP hiPSC_WTa_RNase-pos GSE128135.TBP.hiPSC_WTa_RNase-pos 322 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 371 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 279 bp overlap

TCF12 1 dataset

ChIP H1 ENCFF203EBH 251 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 394 bp overlap

TFAP2A 2 datasets

Motif DE_24h DE_24h-TFAP2A_MA0810.2 11 bp overlap

Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap

THAP1 2 datasets

Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

Motif ES_0h ES_0h-THRA_MA1969.2 18 bp overlap

TP53 2 datasets

ChIP H9 GSE142050.TP53.H9 445 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 340 bp overlap

ChIP foreskin GSE126390.TP63.foreskin 132 bp overlap

ChIP H1 ENCFF090WVU 241 bp overlap

VEZF1 1 dataset

Motif ES_0h ES_0h-VEZF1_MA1578.2 6 bp overlap

ChIP H1 ENCFF524BTL 227 bp overlap

ChIP K562 ENCFF660QRE 303 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 216 bp overlap

ChIP NT2/D1 ENCFF999MII 310 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 433 bp overlap

ZEB1 2 datasets

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap

ZFP42 1 dataset

Motif DE_24h DE_24h-ZFP42_MA1651.2 13 bp overlap

ZNF148 1 dataset

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ZNF281 1 dataset

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ZNF384 2 datasets

Motif DE_24h DE_24h-ZNF384_MA1125.2 8 bp overlap

Motif ES_0h ES_0h-ZNF384_MA1125.2 8 bp overlap

ZNF528 1 dataset

Motif DE_24h DE_24h-ZNF528_MA1597.1 17 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF532 1 dataset

ChIP WTC11 ENCFF373VBX 243 bp overlap

ZNF574 1 dataset

Motif ES_0h ES_0h-ZNF574_MA1982.2 14 bp overlap

ZNF770 2 datasets

Motif DE_24h DE_24h-ZNF770_MA2099.1 8 bp overlap

Motif ES_0h ES_0h-ZNF770_MA2099.1 8 bp overlap