chr12:120,668,575–120,669,135

chr12 : 120,668,575 – 120,669,135

560 bp 98 TFs 14 linked genes

This 560 bp open chromatin element is linked to 14 target genes and is bound by 98 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
MLEC		18.3 kb	Distal	Multiome
CABP1		28.2 kb	Distal	Multiome
CABP1-DT		28.3 kb	Distal	Multiome
UNC119B		41.6 kb	Distal	Multiome
POP5		87.5 kb	Distal	Multiome
RNF10		134.5 kb	Distal	Multiome
COQ5		139.7 kb	Distal	Multiome
DYNLL1		172.7 kb	Distal	Multiome
SRSF9		199.1 kb	Distal	Multiome
GATC		222.4 kb	Distal	Multiome
TRIAP1		222.4 kb	Distal	Multiome
COX6A1		230.7 kb	Distal	Multiome
SPPL3		235.5 kb	Distal	Multiome
MSI1		299.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 134 bp overlap

ChIP myofibroblast GSE90772.AR.myofibroblast 64 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 431 bp overlap

ChIP 501-mel GSE95280.ARNT.501-mel 279 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 560 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 431 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 190 bp overlap

Motif ES_0h ES_0h-ATF4_MA0833.3 10 bp overlap

ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 92 bp overlap

BCL6 2 datasets

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 323 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 155 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 288 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 112 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 193 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 155 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 201 bp overlap

BRD4 7 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 560 bp overlap

ChIP VCaP GSE148358.BRD4.VCaP 94 bp overlap

ChIP VCaP_R1881 GSE148358.BRD4.VCaP_R1881 78 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 93 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 169 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 84 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 560 bp overlap

ChIP K-562 ENCSR000ATW.CBX8.K-562 560 bp overlap

ChIP A-375_A771726 GSE57431.CDK9.A-375_A771726 150 bp overlap

CEBPA 1 dataset

Motif ES_0h ES_0h-CEBPA_MA0102.5 10 bp overlap

CEBPB 2 datasets

ChIP H1 ENCFF871PTR 181 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 148 bp overlap

CEBPG 1 dataset

Motif ES_0h ES_0h-CEBPG_MA1636.2 10 bp overlap

ChIP T-47D GSE62428.CHD8.T-47D 144 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 155 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 107 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 262 bp overlap

CTCF 11 datasets

ChIP H1 ENCFF764RHO 184 bp overlap

ChIP HAP1 GSE152721.CTCF.HAP1 125 bp overlap

ChIP HAP1_clone21 GSE152721.CTCF.HAP1_clone21 275 bp overlap

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 244 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 179 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 207 bp overlap

ChIP HAP1_clone21_TSS-CRISPR GSE152721.CTCF.HAP1_clone21_TSS-CRISPR 216 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 91 bp overlap

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 88 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 117 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 65 bp overlap

Cebpa 15 datasets

ChIP BLaER1 ENCFF031ISE 370 bp overlap

ChIP BLaER1 ENCFF093OYK 355 bp overlap

ChIP BLaER1 ENCFF250ODG 354 bp overlap

ChIP BLaER1 ENCFF274GAT 268 bp overlap

ChIP BLaER1 ENCFF335XTP 325 bp overlap

ChIP BLaER1 ENCFF341QPD 309 bp overlap

ChIP BLaER1 ENCFF346MCV 187 bp overlap

ChIP BLaER1 ENCFF364PUR 308 bp overlap

ChIP BLaER1 ENCFF399AYC 300 bp overlap

ChIP BLaER1 ENCFF460KDD 215 bp overlap

ChIP BLaER1 ENCFF508JZF 173 bp overlap

ChIP BLaER1 ENCFF798NMV 251 bp overlap

ChIP BLaER1 ENCFF844FIP 299 bp overlap

ChIP BLaER1 ENCFF858JKM 194 bp overlap

ChIP BLaER1 ENCFF896HSY 175 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 60 bp overlap

Ddit3::Cebpa 1 dataset

Motif ES_0h ES_0h-Ddit3Cebpa_MA0019.2 10 bp overlap

ChIP ASC GSE54889.EBF1.ASC 147 bp overlap

EGR1 3 datasets

ChIP K-562 ENCSR000BNE.EGR1.K-562 142 bp overlap

ChIP K562 ENCFF006PJY 245 bp overlap

ChIP fibroblast_DOX-24h GSE134924.EGR1.fibroblast_DOX-24h 213 bp overlap

ChIP HEK293 ENCFF336LFH 115 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 256 bp overlap

ESR1 8 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 158 bp overlap

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 103 bp overlap

ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 257 bp overlap

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 52 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 150 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 91 bp overlap

ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 301 bp overlap

ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 138 bp overlap

ChIP WTC11 ENCFF812SCD 338 bp overlap

ChIP WSU-DLCL2 GSE45982.EZH2.WSU-DLCL2 80 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 535 bp overlap

HDAC6 1 dataset

ChIP GM12878 ENCSR933EYC.HDAC6.GM12878 265 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 88 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 214 bp overlap

KDM4A 1 dataset

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 162 bp overlap

KLF4 2 datasets

ChIP HAP1 GSE130417.KLF4.HAP1 149 bp overlap

ChIP HAP1 GSE130417.KLF4.HAP1 208 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 54 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 170 bp overlap

ChIP melanocyte GSE115845.MAX.melanocyte 201 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 160 bp overlap

ChIP SEM GSE83671.MED.SEM 76 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 135 bp overlap

MEF2D 1 dataset

ChIP retina_Hu21 GSE137311.MEF2D.retina_Hu21 81 bp overlap

ChIP melanocyte_CTR GSE50681.MITF.melanocyte_CTR 160 bp overlap

Motif ES_0h ES_0h-MTF1_MA0863.1 14 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 149 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 96 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 167 bp overlap

NANOG 7 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 432 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 197 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 157 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 560 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 323 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 223 bp overlap

ChIP hESC GSE18292.NANOG.hESC 109 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 246 bp overlap

NR1H4::RXRA 1 dataset

Motif ES_0h ES_0h-NR1H4RXRA_MA1146.2 13 bp overlap

NR4A2::RXRA 1 dataset

Motif ES_0h ES_0h-NR4A2RXRA_MA1147.2 13 bp overlap

OLIG2 1 dataset

ChIP brain-prefrontal-cortex_2017014 GSE129039.OLIG2.brain-prefrontal-cortex_2017014 141 bp overlap

PATZ1 1 dataset

ChIP HEK293 ENCSR966ULI.PATZ1.HEK293 58 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 520 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 206 bp overlap

POLR2A 1 dataset

ChIP GM19193 ENCFF599VTO 465 bp overlap

POU5F1 10 datasets

ChIP BG03 GSE21614.POU5F1.BG03 136 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 329 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 302 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 560 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 121 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 261 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 164 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 491 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 455 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 253 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 291 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 274 bp overlap

RAD21 6 datasets

ChIP GP5D GSE51234.RAD21.GP5D 65 bp overlap

ChIP HAP1 GSE126634.RAD21.HAP1 560 bp overlap

ChIP HAP1 GSE152721.RAD21.HAP1 176 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 551 bp overlap

ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 202 bp overlap

ChIP HCT-116 GSE131606.RAD21.HCT-116 194 bp overlap

RBBP5 1 dataset

ChIP H1 ENCFF905HFL 560 bp overlap

ChIP HCC1599 GSE116871.RBPJ.HCC1599 75 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 148 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 70 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 272 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 223 bp overlap

SIN3A 1 dataset

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 77 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 105 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 139 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 184 bp overlap

SMARCA4 5 datasets

ChIP A-549_AG15690 GSE132290.SMARCA4.A-549_AG15690 102 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 75 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 227 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 560 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 263 bp overlap

SMARCB1 3 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 270 bp overlap

ChIP hiPSC GSE124903.SMARCB1.hiPSC 67 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 392 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 120 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 427 bp overlap

ChIP HAP1_WaplKO-33_SCC4KO GSE94992.SMC1.HAP1_WaplKO-33_SCC4KO 87 bp overlap

SOX2 4 datasets

ChIP HNSC GSE69479.SOX2.HNSC 278 bp overlap

ChIP OSKM GSE81899.SOX2.OSKM 149 bp overlap

ChIP hESC GSE18292.SOX2.hESC 108 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 252 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 110 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 199 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 153 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 150 bp overlap

TCF3 2 datasets

ChIP NPC GSE154479.TCF3.NPC 361 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 63 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 279 bp overlap

TFAP2A 3 datasets

Motif ES_0h ES_0h-TFAP2A_MA0003.5 9 bp overlap

Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap

Motif ES_0h ES_0h-TFAP2A_MA0872.1 13 bp overlap

TFAP2B 3 datasets

Motif ES_0h ES_0h-TFAP2B_MA0811.2 11 bp overlap

Motif ES_0h ES_0h-TFAP2B_MA0813.1 13 bp overlap

ChIP SK-N-SH ENCFF869XXQ 111 bp overlap

TFAP2C 5 datasets

Motif ES_0h ES_0h-TFAP2C_MA0524.3 11 bp overlap

Motif ES_0h ES_0h-TFAP2C_MA0814.3 9 bp overlap

Motif ES_0h ES_0h-TFAP2C_MA0815.1 13 bp overlap

ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 388 bp overlap

ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 171 bp overlap

THAP1 1 dataset

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 324 bp overlap

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 83 bp overlap

ZBTB20 1 dataset

ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 141 bp overlap

ZBTB48 1 dataset

ChIP HEK293 ENCSR781EQJ.ZBTB48.HEK293 67 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 291 bp overlap

ZBTB8A 1 dataset

ChIP HEK293 ENCSR481FEC.ZBTB8A.HEK293 224 bp overlap

ChIP GM12878 ENCSR000BND.ZEB1.GM12878 254 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 143 bp overlap

ZFP36 2 datasets

ChIP GM12878 ENCSR900XDB.ZFP36.GM12878 142 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 169 bp overlap

ZNF692 2 datasets

ChIP HEK293 ENCFF040AZE 236 bp overlap

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 114 bp overlap

ZNF770 3 datasets

ChIP HEK293 ENCFF468FCG 204 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 292 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 213 bp overlap

ZSCAN21 1 dataset

ChIP HEK293 ENCFF582WUP 146 bp overlap